Assessment of reproductive biomarkers in three-spined stickleback (Gasterosteus aculeatus) from sewage effluent recipients.

abstract：:Toxins in cyanobacteria are a recognized risk in the treatment of drinking-water treatment. Cyanotoxins can occur in two modifications: cell bound and dissolved in water. The process of toxin release may occur naturally, but it also may be induced through the processes of drinking-water treatment. Both causes of relea...

journal_title：Environmental toxicology

authors： Schmidt W,Willmitzer H,Bornmann K,Pietsch J

更新日期：2002-01-01 00:00:00

abstract：:The present study was designed to understand the oxidative stress potential of fenthion, an organophosphate (OP) pesticide and its involvement in glutathione metabolism modulated buthionine sulfoximine (BSO, 50 mg/kg) and N-acetylcysteine (NAC, 100 mg/kg) in the brain of fish, Oreochromis niloticus. A sublethal fenthi...

journal_title：Environmental toxicology

authors： Piner P,Sevgiler Y,Uner N

更新日期：2007-12-01 00:00:00

abstract：:Ecological risk assessments are, in part, based on results of toxicity tests conducted under standard exposure conditions. Global climate change will have a wide range of effects on estuarine habitats, including potentially increasing water temperature and salinity, which may alter the risk assessment of estuarine pol...

journal_title：Environmental toxicology

authors： DeLorenzo ME,Danese LE,Baird TD

更新日期：2013-07-01 00:00:00

abstract：:The risk presented by β-blockers on aquatic organisms remains uncertain, particularly given the enantiospecific differences in toxicity of chiral β-blockers. In this study, the toxicity of two β-blockers, propranolol and metoprolol, was determined. The 96-h LC50 of propranolol in the zebrafish larvae was 2.48 mg/L, wh...

journal_title：Environmental toxicology

authors： Sun L,Xin L,Peng Z,Jin R,Jin Y,Qian H,Fu Z

更新日期：2014-12-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is the most common type of chronic inflammatory disease which is triggered by dysfunction in the immune system which in turn affects synovial joints. Current treatment of RA with NSAIDs and DMRDs is limited by their side effect. As a result, the interest in alternative, well tolerated anti-in...

journal_title：Environmental toxicology

authors： Neha,Ansari MM,Khan HA

更新日期：2017-02-01 00:00:00

abstract：:2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) are persistent organic pollutants which coexist in environment, and human are co-exposed to these chemicals. Our present study was aimed to investigate the possible enhanced nonalcoholic fatty liver disease (NAFLD) in ApoE(-/-) mice co-exp...

journal_title：Environmental toxicology

authors： Shan Q,Huang F,Wang J,Du Y

更新日期：2015-12-01 00:00:00

abstract：:Ouabain, a cardiotonic steroid, was used for the treatment of heart failure and atrial fibrillation and induces cancer cell apoptosis in many human cancer cells including human leukemia cells. However, there are no reports to show the effects on immune responses in a leukemia mouse model. In this study, WEHI-3 cell ge...

journal_title：Environmental toxicology

authors： Shih YL,Shang HS,Chen YL,Hsueh SC,Chou HM,Lu HF,Lee MZ,Hou HT,Chuang YY,Lee MH,Chen KW,Chung JG

更新日期：2019-05-01 00:00:00

abstract：:In the present study, responses of the Chinese brown frog (Rana chensinensis) to exposure to di-2-ethylhexyl phthalate (DEHP), a common plasticizer, during the larval period were characterized. The effects of DEHP on metamorphosis rate, thyroid hormone, thyroid histology and the expression of genes involved in the ste...

journal_title：Environmental toxicology

authors： Zhang Y,Li X,Gao J,Wang H

更新日期：2018-01-01 00:00:00

abstract：:Interspecies differences in the accumulation of dietary tributyltin (TBT) between sea perch, Lateolabrax japonicus, and red sea bream, Pagrus major, were studied. Although TBTs in both species reached steady-state condition in low-concentration group (L-group, 200 ng/g nominal concentration) by 1 week, it increased up...

journal_title：Environmental toxicology

authors： Uno S,Murakami M,Kokushi E,Koyama J

更新日期：2011-02-01 00:00:00

abstract：:Cyanotoxins are a group of compounds produced by cyanobacteria that can have severe physiological effects on other organisms, including humans. The potential allelopathic effects of Microcystis aeruginosa, a toxic cyanobacterium, on the duckweed plant, Lemna gibba L., were examined using three experimental methods: (1...

journal_title：Environmental toxicology

authors： LeBlanc S,Pick FR,Aranda-Rodriguez R

更新日期：2005-02-01 00:00:00

abstract：:The 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidized nucleoside of DNA, not only is a widely used biomarker for the measurement of endogenous oxidative DNA damage, but might also be a risk factor for many diseases including cancer. Elevated level of urinary 8-OHdG has been detected in patients with various malignanci...

journal_title：Environmental toxicology

authors： Yang Y,Tian Y,Yan C,Jin X,Tang J,Shen X

更新日期：2009-10-01 00:00:00

abstract：:Petroleum products-petrol, kerosene, and diesel-composed of volatile organic constituents contribute to air pollution. Exposure of gas station attendants (GSAs) to petroleum products fumes (PPFs) may account for occupation-related predisposition to respiratory toxicity and disease pathogenesis. We simulated GSA exposu...

journal_title：Environmental toxicology

authors： Owumi SE,Elebiyo TC,Oladimeji BN

更新日期：2020-09-07 00:00:00

abstract：:Particulate matter 2.5 (PM2.5)-induced pulmonary inflammation has become a public concern in recent years. In which, the activation of the NLRP3/caspase-1 pathway was closely related to the inflammatory response of various diseases. However, the promotion effect of the NLRP3/caspase-1 pathway on PM2.5-induced pulmonar...

journal_title：Environmental toxicology

authors： Jia H,Liu Y,Guo D,He W,Zhao L,Xia S

更新日期：2020-09-30 00:00:00

abstract：:Microcystin-LR (MC-LR) is the most commonly encountered of the toxic cyclic peptide hepatotoxins occurring in China. It is a model compound for toxicological studies. In this study, the toxicity of MC-LR (50 and 500 micrograms/L) on isolated carp hepatocytes was determined and the ultrastructural alterations of cells ...

journal_title：Environmental toxicology

authors： Li X,Liu Y,Song L

更新日期：2001-01-01 00:00:00

abstract：:Tris (1,3-dichloro-2-propyl) phosphate (TDCIPP) is one of the widely used organophosphorus flame retardants (OPFRs), which are regarded as suitable substitutes for brominated flame retardants (BFRs). Previously, we have validated the toxicity of TDCIPP in PC12 cells owing to the induced alterations in GAP43, NF-H, CaM...

journal_title：Environmental toxicology

authors： Li C,Li L,Lin B,Fang Y,Yang H,Liu H,Xi Z

更新日期：2017-06-01 00:00:00

abstract：:Sick building syndrome (SBS) is a set of several clinically recognizable symptoms reported by occupants of a building without a clear cause. Neuropathy target esterase (NTE) is a membrane bound serine esterase and its reaction with organophosphates (OPs) can lead to OP-induced delayed neuropathy (OPIDN) and nerve axon...

journal_title：Environmental toxicology

authors： Matsuzaka Y,Ohkubo T,Kikuti YY,Mizutani A,Tsuda M,Aoyama Y,Kakuta K,Oka A,Inoko H,Sakabe K,Ishikawa S,Kulski JK,Kimura M

更新日期：2014-10-01 00:00:00

abstract：:Dicrotophos is a systemic insecticide with a wide range of applications. We investigated the genotoxicity of dicrotophos using the Ames test, the chromosome aberration test in CHO-K1 cells, and the comet assay in the Hep G2 cells, while this chemicals' toxicity to both the cell lines was evaluated with the MTT assay. ...

journal_title：Environmental toxicology

authors： Wu JC,Chye SM,Shih MK,Chen CH,Yang HL,Chen SC

更新日期：2012-05-01 00:00:00

abstract：:Multi-walled carbon nanotubes (MWCNTs) have many applications in industry and used as additives in polymers, catalysts, anodes in lithium-battery and drug delivery. There is little information about MWCNTs' (210 nm) genotoxic potential on juvenile freshwater fish Channa punctatus. Therefore, in this study, we have det...

journal_title：Environmental toxicology

authors： Ali D,Falodah FA,Almutairi B,Alkahtani S,Alarifi S

更新日期：2020-03-01 00:00:00

abstract：:The environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is known to affect bone metabolism. We evaluated the protective effects of the triterpene glycoside actein from the herb black cohosh against TCDD-induced toxicity in MC3T3-E1 osteoblastic cells. We found that TCDD significantly reduced cell viabil...

journal_title：Environmental toxicology

authors： Choi EM,Suh KS,Jung WW,Park SY,Chin SO,Rhee SY,Pak YK,Chon S

更新日期：2017-12-01 00:00:00

abstract：:Water bodies are routinely monitored for the presence of potentially toxic cyanobacteria; however, the methodology for confirming toxicity is currently complex and expensive. Here we describe the application of gene-based technology to rapidly identify cylindrospermopsin-producing cyanobacteria, specifically, Cylindro...

journal_title：Environmental toxicology

authors： Fergusson KM,Saint CP

更新日期：2003-04-01 00:00:00

abstract：:The cytotoxic and genotoxic effects induced by alachlor and dichlorvos, two pesticides broadly used, were studied on RTG-2 fish cell line. As measure of cytotoxicity, neutral red assay was used to determine the cellular viability. Toxicity ranking based on IC(50) values found that alachlor was more cytotoxic than dich...

journal_title：Environmental toxicology

authors： Parra JM,Sánchez-Fortún S,Castaño A

更新日期：2012-03-01 00:00:00

abstract：:Acute toxicities of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) were tested on four freshwater species and three plant species. PFOS was more toxic than PFOA for all species tested in this study. Similar time-response patterns of PFOS and PFOA toxicity were observed for each tested species. Valu...

journal_title：Environmental toxicology

authors： Li MH

更新日期：2009-02-01 00:00:00

abstract：:Contamination of the urban aquatic environment with chemical and biological substances could have a long-term impact on human health because these substances threaten the integrity of the urban ecosystem and the availability of high-quality water for recreation and consumption. In light of this, the aim of the present...

journal_title：Environmental toxicology

authors： Wichmann G,Daegelmann C,Herbarth O,Strauch G,Schirmer K,Wöstemeyer J,Lehmann I

更新日期：2004-12-01 00:00:00

abstract：:An enormous quantity of pharmacologically active principles are currently being introduced into the environment, with consequent escalation of environmental problems, but only a small number of studies are focusing on an assessment of their genotoxic effects. The aim of this article is to assess the genotoxic effects ...

journal_title：Environmental toxicology

authors： Rocco L,Peluso C,Stingo V

更新日期：2012-10-01 00:00:00

abstract：:Cancer cell stemness results in the occurrence and progression of tumors and Oct4 (octamer-binding transcription factor) has been confirmed to be a critical contributor and marker of cancer cell stemness. Here, we aimed to explore the underlying mechanisms contributing to Oct4 protein stability, which is necessary for...

journal_title：Environmental toxicology

authors： Xu Y,Xu G,Dang H,Qu W,Chang D,He X,Li M,Wang Q

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVES:We evaluated the role of oxidative stress in Sudan IV-induced DNA damage, using human liver-derived HepG2 cells. METHODS:The DNA damaging effects of Sudan IV in HepG2 cells were evaluated by alkaline single cell gel electrophoresis assay and micronucleus test (MNT). To clarify the underlying mechanisms, we ...

journal_title：Environmental toxicology

authors： Zhang Y,An Y,Jiang L,Geng C,Cao J,Jiang L,Zhong L

更新日期：2011-06-01 00:00:00

abstract：:Deguelin, a naturally occurring rotenoid of the flavonoid family, is known to be an Akt inhibitor, to have chemopreventive activities and anti-tumor effect on several cancers. In this study, investigation to elucidate the effect of deguelin on apoptotic pathways in human lung cancer cells and on the anti-tumor effect ...

journal_title：Environmental toxicology

authors： Hsu YC,Chiang JH,Yu CS,Hsia TC,Wu RS,Lien JC,Lai KC,Yu FS,Chung JG

更新日期：2017-01-01 00:00:00

abstract：:Long-term exposure of agriculturally used organochloride and organophosphate pesticides have been shown to cause long-lasting hematotoxicity and increased incidence of aplastic anemia in humans. The mechanisms involved in pesticide induced hematotoxicity and the features of toxicity that may play a major role in bone ...

journal_title：Environmental toxicology

authors： Chatterjee S,Basak P,Chaklader M,Das P,Pereira JA,Chaudhuri S,Law S

更新日期：2014-01-01 00:00:00

abstract：:Adrenomedullin (AdM) is synthesized and secreted by a number of cells and tissue. AdM is a potent vasodilator but it is also considered a neuromodulator, an angiogenic factor, and a hormone regulator. AdM possess antiapoptotic, antioxidant, and antimicrobial properties. Heavy metals such as cadmium and lead are found ...

journal_title：Environmental toxicology

authors： Yurekli M,Esrefoglu M,Ilker Doğru M,Doğru A,Gul M,Whidden M

更新日期：2009-06-01 00:00:00

abstract：:Casticin, a polymethoxyflavone, is one of the major active components obtained from Fructus viticis, which have been shown to have anticancer activities including induce cell apoptosis in human cancer cells. The aim of this study was to investigate the molecular mechanisms by which casticin inhibits cell migration and...

journal_title：Environmental toxicology

authors： Shih YL,Chou HM,Chou HC,Lu HF,Chu YL,Shang HS,Chung JG

更新日期：2017-09-01 00:00:00