Prophylaxis of hepatitis B infection in solid organ transplant recipients.

abstract：Objective:i-Scan is a digital image enhancement technology, reported to improve diagnostic performance during endoscopy. Previous studies have investigated the accuracy of i-scan for distinguishing between neoplastic and non-neoplastic colonic polyps and suggested diagnostic accuracy close to that required for use in r...

journal_title：Therapeutic advances in gastroenterology

authors： Glover B,Patel N,Ashrafian H,Teare J

更新日期：2018-12-06 00:00:00

abstract：BACKGROUND:Mast cells (MCs) can stimulate angiogenesis, releasing several proangiogenic cytokines stored in their cytoplasm. In particular, MCs can release tryptase, a potent in vivo and in vitro proangiogenic factor via protease-activated receptor-2 (PAR-2) activation and mitogen-activated protein kinase (MAPK) phosph...

journal_title：Therapeutic advances in gastroenterology

authors： Ammendola M,Sacco R,Vescio G,Zuccalà V,Luposella M,Patruno R,Zizzo N,Gadaleta C,Marech I,Ruggieri R,Kocak IF,Ozgurtas T,Gadaleta CD,Sammarco G,Ranieri G

更新日期：2017-04-01 00:00:00

abstract：:The wireless motility capsule (WMC) is an ambulatory noninvasive and nonradioactive diagnostic sensor that continuously samples intraluminal pH, temperature, and pressure as it moves through the gastrointestinal (GI) tract. This review summarizes the data obtained in clinical trials with the WMC and discusses its role...

journal_title：Therapeutic advances in gastroenterology

authors： Tran K,Brun R,Kuo B

更新日期：2012-07-01 00:00:00

abstract：:Crohn's disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal tract with no known cure. The inflammation that drives the disease can lead to debilitating symptoms and a number of complications that may lead to surgery. The introduction of biologic therapy a decade ago has offered a new opt...

journal_title：Therapeutic advances in gastroenterology

authors： Panaccione R,Ghosh S

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Self-expandable metal stent (SEMS) placement is a minimally invasive treatment for palliation of malignant colorectal strictures and as a bridge to surgery. However, the use of SEMS for benign colorectal diseases is controversial. The purpose of this retrospective study is to evaluate the efficacy and safety...

journal_title：Therapeutic advances in gastroenterology

authors： Cereatti F,Fiocca F,Dumont JL,Ceci V,Vergeau BM,Tuszynski T,Meduri B,Donatelli G

更新日期：2016-03-01 00:00:00

abstract：Background and Aims:Efficacy of adalimumab in Crohn's disease (CD) has not been shown in China. The aim of this study was to evaluate the efficacy and safety of adalimumab in Chinese patients with CD. Methods:This 26-week, multicenter, phase III study evaluated patients with moderately to severely active CD and elevat...

journal_title：Therapeutic advances in gastroenterology

authors： Chen B,Gao X,Zhong J,Ren J,Zhu X,Liu Z,Wu K,Kalabic J,Yu Z,Huang B,Kwatra N,Doan T,Robinson AM,Chen MH

更新日期：2020-07-16 00:00:00

abstract：:In this article we provide a contemporary overview of available clinical data on certolizumab pegol, a pegylated anti-tumor necrosis factor (TNF) alpha agent that comprises a uniquely small protein, and its emerging role as a therapy for Crohn's disease (CD). The results from a comprehensive clinical trial program sug...

journal_title：Therapeutic advances in gastroenterology

authors： Schreiber S

更新日期：2011-11-01 00:00:00

abstract：:Severe acute pancreatitis (SAP) is a critical abdominal disease associated with high death rates. A systemic inflammatory response promotes disease progression, resulting in multiple organ dysfunction. The functions of neutrophils in the pathology of SAP have been presumed traditionally to be activation of chemokine a...

journal_title：Therapeutic advances in gastroenterology

authors： Hu J,Kang H,Chen H,Yao J,Yi X,Tang W,Wan M

更新日期：2020-11-24 00:00:00

abstract：:In 2010, four independent groups almost simultaneously reported the association of the novel interleukin-1 (IL-1) family member, IL-33, with inflammatory bowel disease (IBD). The findings were remarkably consistent and demonstrated that IL-33 is markedly upregulated in, and specific to, ulcerative colitis (UC). In add...

journal_title：Therapeutic advances in gastroenterology

authors： Pastorelli L,De Salvo C,Cominelli MA,Vecchi M,Pizarro TT

更新日期：2011-09-01 00:00:00

abstract：Background:Recently the American Society for Gastrointestinal Endoscopy addressed the 'resect and discard' strategy, determining that accurate in vivo differentiation of colorectal polyps (CP) is necessary. Previous studies have suggested a promising application of artificial intelligence (AI), using deep learning in o...

journal_title：Therapeutic advances in gastroenterology

authors： Ozawa T,Ishihara S,Fujishiro M,Kumagai Y,Shichijo S,Tada T

更新日期：2020-03-20 00:00:00

abstract：OBJECTIVES:Clinical evidence regarding radiological-endoscopic management of intrahepatic bile duct stones is currently lacking. Our aim is to report our 18-year experience in combined radiological-endoscopic management of intrahepatic difficult bile duct stones. METHODS:From June 1994 to June 2012, 299 symptomatic pa...

journal_title：Therapeutic advances in gastroenterology

authors： Cannavale A,Bezzi M,Cereatti F,Lucatelli P,Fanello G,Salvatori FM,Fanelli F,Fiocca F,Donatelli G

更新日期：2015-11-01 00:00:00

abstract：:Sex-based differences in inflammatory bowel disease (IBD) pathogenesis, disease course, and response to therapy have been increasingly recognized, however, not fully understood. Experimental and translational models have been leveraged to investigate hypothesized mechanisms for these observed differences, including th...

journal_title：Therapeutic advances in gastroenterology

authors： Rustgi SD,Kayal M,Shah SC

更新日期：2020-04-28 00:00:00

abstract：:Several clinical trials and experimental studies strongly suggest a place for Saccharomyces boulardii as a biotherapeutic agent for the prevention and treatment of several gastrointestinal diseases. S. boulardii mediates responses resembling the protective effects of the normal healthy gut flora. The multiple mechanis...

journal_title：Therapeutic advances in gastroenterology

authors： Kelesidis T,Pothoulakis C

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Few studies have compared early gastric cancer (EGC) outcomes according to sex and age. METHODS:We retrospectively reviewed 2085 patients who underwent curative gastrectomy for EGC between 1989 and 2000. Prognosis and risk factors for nodal involvement were evaluated according to sex and age. RESULTS:Male ...

journal_title：Therapeutic advances in gastroenterology

authors： Suh DD,Oh ST,Yook JH,Kim BS,Kim BS

更新日期：2017-02-01 00:00:00

abstract：Background:The environment surrounding Helicobacter pylori eradication treatment is dramatically changing. Recently, vonoprazan, a first-in-class potassium-competitive acid blocker (P-CAB), was introduced onto the market in 2015. The aging of Japan's demographic structure is becoming pronounced. In this study, we exami...

journal_title：Therapeutic advances in gastroenterology

authors： Mori H,Suzuki H,Omata F,Masaoka T,Asaoka D,Kawakami K,Mizuno S,Kurihara N,Nagahara A,Sakaki N,Ito M,Kawamura Y,Suzuki M,Shimada Y,Sasaki H,Matsuhisa T,Torii A,Nishizawa T,Mine T,Ohkusa T,Kawai T,Tokunaga K,Tak

更新日期：2019-07-04 00:00:00

abstract：:Clostridium difficile was first described as a cause of diarrhea in 1978 and in the last three decades has reached an epidemic state with increasing incidence and severity in both healthcare and community settings. There also has been a rise in severe outcomes from C. difficile infection (CDI). There have been tremend...

journal_title：Therapeutic advances in gastroenterology

authors： Khanna S,Pardi DS

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Diarrhea-predominant irritable bowel syndrome (IBS-D) impairs patient quality of life (QOL). Rifaximin is an oral, nonsystemic antibiotic indicated for IBS-D. The objective of this secondary analysis was to evaluate rifaximin retreatment on IBS-related QOL in patients with IBS-D. METHODS:Patients received o...

journal_title：Therapeutic advances in gastroenterology

authors： Cash BD,Pimentel M,Rao SSC,Weinstock L,Chang L,Heimanson Z,Lembo A

更新日期：2017-09-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common arrhythmia worldwide and is associated with significant morbidity and mortality. A number of risk factors have been associated with AF, though few studies have explored the association between gastrointestinal and liver diseases and AF. Additionally, AF and treatment for AF ...

journal_title：Therapeutic advances in gastroenterology

authors： Long MT,Ko D,Arnold LM,Trinquart L,Sherer JA,Keppel SS,Benjamin EJ,Helm RH

更新日期：2019-04-02 00:00:00

abstract：:Monoclonal antibodies to tumor necrosis factor (TNF) have become a mainstay of the therapeutic armamentarium in inflammatory bowel disease (IBD) over the last 15 years. Although highly effective, primary and secondary nonresponse are common and associated with poor clinical outcomes and significant costs. Multiple cli...

journal_title：Therapeutic advances in gastroenterology

authors： Kopylov U,Seidman E

更新日期：2016-07-01 00:00:00

abstract：METHODS:Suboptimal bowel preparation, present in over 20% of colonoscopies, can severely compromise the effectiveness of the colonoscopy procedure. We surveyed 93 primarily urban minority men and women who underwent asymptomatic 'screening' colonoscopy regarding their precolonoscopy bowel-preparation experience. RESUL...

journal_title：Therapeutic advances in gastroenterology

authors： Basch CH,Basch CE,Wolf RL,Zybert P,Lebwohl B,Shmukler C,Neugut AI,Shea S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Dual red imaging (DRI), a novel image-enhanced endoscopic technique, is expected to improve visibility of thin vessels, but no reports of the clinical use of DRI in colorectal endoscopic submucosal dissection (ESD) have been published. We aimed to compare the visibility of vessels, demarcation line between t...

journal_title：Therapeutic advances in gastroenterology

authors： Ninomiya Y,Oka S,Tanaka S,Hirano D,Sumimoto K,Tamaru Y,Asayama N,Shigita K,Nishiyama S,Hayashi N,Chayama K

更新日期：2016-09-01 00:00:00

abstract：Background:The clinical outcome of patients with obscure gastrointestinal bleeding (OGIB) during antithrombotic drug therapy has not been fully investigated. Methods:Patients who underwent video capsule endoscopy (VCE) for the investigation of OGIB at Okayama University Hospital from January 2009 to March 2016 were en...

journal_title：Therapeutic advances in gastroenterology

authors： Kono Y,Kawano S,Okamoto Y,Obayashi Y,Baba Y,Sakae H,Abe M,Gotoda T,Inokuchi T,Kanzaki H,Iwamuro M,Kawahara Y,Okada H

更新日期：2018-01-14 00:00:00

abstract：Aims:Gastric cancer (GC) is the third leading cause of cancer death worldwide, but the burden of disease is not distributed evenly. GC screening routinely occurs in some high-incidence regions/countries and is generally cost-effective, which is attributed largely to the associated GC mortality reduction. In regions of ...

journal_title：Therapeutic advances in gastroenterology

authors： Canakis A,Pani E,Saumoy M,Shah SC

更新日期：2020-07-16 00:00:00

abstract：:The human gastrointestinal tract comprises a series of complex and dynamic organs ranging from the stomach to the distal colon, which harbor immense microbial assemblages that are known to be vital for human health. Until recently, most of the details concerning our gut microbiota remained obscure. Over the past sever...

journal_title：Therapeutic advances in gastroenterology

authors： Kovatcheva-Datchary P,Zoetendal EG,Venema K,de Vos WM,Smidt H

更新日期：2009-07-01 00:00:00

abstract：:Chronic hepatitis C (CHC) affects over 185 million individuals worldwide, approximately 3% of the world's population. CHC can lead to quality of life impairment, cirrhosis, hepatocellular carcinoma (HCC), liver failure and liver-related death. While CHC has been associated with increases in HCC, liver-related mortalit...

journal_title：Therapeutic advances in gastroenterology

authors： Lam BP,Jeffers T,Younoszai Z,Fazel Y,Younossi ZM

更新日期：2015-09-01 00:00:00

abstract：:In recent years, mucosal healing has emerged as a key therapeutic goal in the clinical management of patients with Crohn's disease, as it has been associated with improved long-term clinical outcomes. With the vast improvements in endoscopic imaging techniques and the increase in available treatment options, which rep...

journal_title：Therapeutic advances in gastroenterology

authors： Klenske E,Bojarski C,Waldner M,Rath T,Neurath MF,Atreya R

更新日期：2019-06-14 00:00:00

abstract：Background:Pharmacotherapy, including prokinetics and proton pump inhibitors for functional dyspepsia (FD) have limited effectiveness, and their safety has been recently questioned. Chinese herbal medicine (CHM) could be considered as an alternative. A systematic review (SR) of SRs was performed to evaluate the potenti...

journal_title：Therapeutic advances in gastroenterology

authors： Chu MHK,Wu IXY,Ho RST,Wong CHL,Zhang AL,Zhang Y,Wu JCY,Chung VCH

更新日期：2018-07-16 00:00:00

abstract：Introduction:Hepatocholangiocarcinoma (HCC-ICC) is a rare tumor presenting the histologic characteristics of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). As there is no consensus on it management, the therapeutic strategy rests on the specific treatments for HCC or ICC. Programmed cell...

journal_title：Therapeutic advances in gastroenterology

authors： Saint A,Benchetrit M,Novellas S,Ouzan D,Falk AT,Leysalle A,Barriere J

更新日期：2020-06-20 00:00:00

abstract：:Gut microbiota is a compilation of microorganisms dwelling in the entire mammalian gastrointestinal tract. They display a symbiotic relationship with the host contributing to its intestinal health and disease. Even a slight fluctuation in this equipoise may be deleterious to the host, leading to many pathological cond...

journal_title：Therapeutic advances in gastroenterology

authors： Bien J,Palagani V,Bozko P

更新日期：2013-01-01 00:00:00

abstract：Background:Vedolizumab (VDZ) is a gut-specific α4-β7 integrin antagonist that has demonstrated efficacy in Crohn's disease (CD) and ulcerative colitis (UC). The safety of VDZ in the perioperative period remains unclear. The aim of this study was to evaluate postoperative complications and perioperative safety in VDZ-tr...

journal_title：Therapeutic advances in gastroenterology

authors： Kotze PG,Ma C,Mckenna N,Almutairdi A,Kaplan GG,Raffals LE,Loftus EV Jr,Panaccione R,Lightner AL

更新日期：2018-06-21 00:00:00