Targeting mucosal healing in Crohn's disease: what the clinician needs to know.

Abstract:

:In recent years, mucosal healing has emerged as a key therapeutic goal in the clinical management of patients with Crohn's disease, as it has been associated with improved long-term clinical outcomes. With the vast improvements in endoscopic imaging techniques and the increase in available treatment options, which reportedly are able to induce mucosal healing, the practising physician is left to wonder: how is endoscopic mucosal healing exactly defined in Crohn's disease, and how can it effectively be achieved and monitored in daily clinical practice? Within this review, we will give an overview of the ongoing debate about the definition of mucosal healing and the modalities to monitor inflammation, and finally present available therapies with the capacity to induce mucosal healing.

authors

Klenske E,Bojarski C,Waldner M,Rath T,Neurath MF,Atreya R

doi

10.1177/1756284819856865

subject

Has Abstract

pub_date

2019-06-14 00:00:00

pages

1756284819856865

eissn

1756-283X

issn

1756-2848

pii

10.1177_1756284819856865

journal_volume

12

pub_type

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