Abstract：
BACKGROUND:The ability to predict potential for relapse to substance use following treatment could be very useful in targeting aftercare strategies. Recently, a number of investigators have focused on using neural activity measured by fMRI to predict relapse propensity. The purpose of the present study was to use fMRI to investigate prospective associations between brain reactivity to cocaine and response inhibition cues and relapse to cocaine use. METHODS:Thirty cocaine-dependent participants with clean cocaine urine drug screens (UDS) completed a baseline fMRI scan, including a cocaine-cue reactivity task and a go no-go response inhibition task. After participating in a brief clinical trial of d-cycloserine for the facilitation of cocaine-cue extinction, they returned for a one-week follow-up UDS. Associations between baseline activation to cocaine and inhibition cues and relapse to cocaine use were explored. RESULTS:Positive cocaine UDS was significantly associated with cocaine-cue activation in the right putamen and insula, as well as bilateral occipital regions. Associations between positive cocaine UDS and activation to no-go cues were concentrated in the postcentral gyri, a region involved in response execution. CONCLUSIONS:Although preliminary, these results suggest that brain imaging may be a useful tool for predicting risk for relapse in cocaine-dependent individuals. Further, larger-scale naturalistic studies are needed to corroborate and extend these findings.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Prisciandaro JJ,Myrick H,Henderson S,McRae-Clark AL,Brady KTdoi
10.1016/j.drugalcdep.2013.04.008subject
Has Abstractpub_date
2013-07-01 00:00:00pages
44-9issue
1-2eissn
0376-8716issn
1879-0046pii
S0376-8716(13)00136-1journal_volume
131pub_type
杂志文章,随机对照试验abstract：:This study examined the predictors of self-reported health status at follow-up in the Drug Abuse Treatment Outcomes Study (DATOS), a longitudinal study of drug abuse treatment programs and patients in 1991-1993. Baseline and follow-up interviews of 2966 patients in 75 programs were performed. The follow-up assessment ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/s0376-8716(02)00323-x
更新日期：2003-04-01 00:00:00
abstract：:The relative and combined health effects of cigarette smoking, heroin use, and depression were examined in 322 clinically depressed smokers and 117 opioid-dependent smokers participating in two studies of the San Francisco Treatment Research Center. Opioid-dependent smokers averaged 16 years (S.D.=9) of heroin use; 3%...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2004.10.012
更新日期：2005-05-09 00:00:00
abstract：BACKGROUND:Many young adults engage in simultaneous alcohol and marijuana (SAM) use so that their effects overlap. Little is known about motivations for dual substance use and associations with use and consequences. This study examined daily-level associations between cross-fading motives and levels of alcohol and mari...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
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abstract：BACKGROUND:In recent years, scientific evidence has emerged that wastewater-based epidemiology can deliver complementary information concerning the use of different substances of abuse. In this study, the potential of wastewater-based epidemiology in monitoring spatial and temporal trends in alcohol consumption in diff...
journal_title：Drug and alcohol dependence
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2008.03.025
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journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2008.03.026
更新日期：2008-09-01 00:00:00
abstract：:There is a considerable disparity between the number of individuals who need substance abuse treatment and the number who actually receive it. This is partly due to the fact that many individuals with substance use disorders do not perceive a need for formal treatment. Another contributing factor, however, is a discre...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2009.05.014
更新日期：2009-10-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章,评审
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更新日期：2020-01-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(91)90011-m
更新日期：1991-05-01 00:00:00
abstract：AIMS:The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) is a screening instrument to detect substance use in primary care (PC). To screen for illicit substances (excluding tobacco and alcohol), the ASSIST consists of 8-57 questions and requires complicated scoring. To improve the efficiency of scree...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2016.03.029
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Substance use treatment is rarely a one-time event for individuals with substance use disorders. Sustained reductions in substance use and its related symptoms may result from multiple treatment episodes. METHODS:We use a marginal structural model with inverse-probability-of-treatment weighting to estimate ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.12.017
更新日期：2014-03-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2014.02.011
更新日期：2014-05-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(93)90033-m
更新日期：1993-06-01 00:00:00
abstract：BACKGROUND:Amphetamine abuse is increasing worldwide, and the occurrence of amphetamine-induced (AI) psychiatric issues further complicates treatment. In response, the DSM 5 has introduced the classification of amphetamine-induced obsessive-compulsive disorders (AI-OCD), though little has been published on either its p...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.12.034
更新日期：2016-03-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2015.04.010
更新日期：2015-07-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/0376-8716(79)90007-3
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journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2002-09-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2015-05-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2019.01.035
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journal_title：Drug and alcohol dependence
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2002-01-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章,随机对照试验
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更新日期：2011-01-01 00:00:00
abstract：:Serum alcohol dehydrogenase (ADH) activity in some individuals contains a fraction that is not inhibited by pyrazole. This might be due to the presence in those sera of pi-ADH, a unique isoenzyme found recently in human liver, and which, according to one hypothesis, could be co-responsible for the development of alcoh...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
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更新日期：1980-09-01 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2014.04.009
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:Both HIV infection and chronic cocaine use alter the neural circuitry of decision making, but the interactive effects of these commonly comorbid conditions have not been adequately examined. This study tested how cocaine moderates HIV-related neural activation during an intertemporal decision-making task. M...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2017.05.043
更新日期：2017-09-01 00:00:00
abstract：AIMS:This study aimed at examining a possible association between cannabis use in adolescence and future disability pension (DP). DP can be granted to any person in Sweden aged 16-65 years if working capacity is judged to be permanently reduced due to long-standing illness or injury. METHODS:Data were obtained from a ...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2014.07.038
更新日期：2014-10-01 00:00:00
abstract：:Impulsivity appears to play an important role in suicidal behaviors and drug abuse, which are two psychiatric problems that may interact with one another. Interpretation of the literature on impulsivity in these behaviors may be complicated by the variety of measurement techniques for the assessment of impulsivity. Th...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2004.08.010
更新日期：2004-12-07 00:00:00
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journal_title：Drug and alcohol dependence
pub_type： 杂志文章,多中心研究
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更新日期：2007-05-11 00:00:00
abstract：AIMS:To develop an Opioid Overdose Knowledge Scale (OOKS) and an Opioid Overdose Attitudes Scale (OOAS) to evaluate take-home naloxone training. METHODS:Psychometric instrument development study conducted in England using convenience samples. Forty-five items were selected for the OOKS organised in four sub-scales (ri...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
doi：10.1016/j.drugalcdep.2013.02.007
更新日期：2013-09-01 00:00:00
abstract：INTRODUCTION:The objective of this study was to understand how adolescent substance use patterns may lead to negative mental health outcomes. METHODS:Data from adolescents (12-17 years old at baseline, Wave 1) who participated in the first 3 waves of the Population Assessment of Health and Tobacco (PATH) study were us...
journal_title：Drug and alcohol dependence
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
