Adaptive changes in the dopamine system produced by chronic ethanol feeding.

abstract：BACKGROUND:North Carolina, like much of the U.S. South, is disproportionately affected by HIV and hepatitis. This persistently high disease burden may be driven in part by laws that criminalize the possession and distribution of syringes for illicit drug use. Legal change to decriminalize syringes may reduce infection ...

journal_title：Drug and alcohol dependence

authors： Davis CS,Johnston J,de Saxe Zerden L,Clark K,Castillo T,Childs R

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Studies of drinking drivers in alcohol-related crashes have shown that high breath-alcohol concentrations (BrACs) are associated with illegal drug use. Until the 2007 National Roadside Survey (NRS), the prevalence of drugs among drinking drivers on U.S. roads was unknown. Using NRS data, we explore how many ...

journal_title：Drug and alcohol dependence

authors： Voas RB,Lacey JH,Jones K,Scherer M,Compton R

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Smoking, especially nicotine dependence is associated with more severe symptoms of depression and anxiety disorders. However, the mechanisms underlying this association are unclear. We investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive an...

journal_title：Drug and alcohol dependence

authors： Jamal M,Van der Does W,Penninx BW

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To investigate the association of major depressive episode (MDE) with nonmedical prescription opioid use (NMPOU) and opioid abuse/dependence among adolescents aged 12 to 17. METHODS:We analyzed 5 years of data from the National Survey on Drug Use and Health (NSDUH). We used logistic regressions to study the ...

journal_title：Drug and alcohol dependence

authors： Edlund MJ,Forman-Hoffman VL,Winder CR,Heller DC,Kroutil LA,Lipari RN,Colpe LJ

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Opioid use and abuse in the United States continues to expand at an alarming rate. In this study, we examine the county-level determinants of the availability and abuse of prescription opioids to better understand the socio-ecological context, and in particular the role of the healthcare delivery system, on ...

journal_title：Drug and alcohol dependence

authors： Wright ER,Kooreman HE,Greene MS,Chambers RA,Banerjee A,Wilson J

更新日期：2014-05-01 00:00:00

abstract：:Propylhexedrine, a sympathomimetic with varied medicinal uses, is one of the compounds to be reviewed by the Expert Committee convened by the World Health Organization (WHO) to determine whether the compound should be scheduled under the Convention on Psychotropic Substances. This paper reviews the pharmacology, medic...

journal_title：Drug and alcohol dependence

authors： Wesson DR

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:The theoretical benefits of naltrexone as a treatment for opioid use disorder (e.g., safety, non-addictive, low risk of diversion) stand in sharp contrast to its disappointing record on retention in most samples. The relationship of uncomfortable physical and dysphoric symptoms to retention on naltrexone is ...

journal_title：Drug and alcohol dependence

authors： Carroll KM,Nich C,Frankforter TL,Yip SW,Kiluk BD,DeVito EE,Sofuoglu M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Methamphetamine has become one of the most widely used illicit substances in the world. We measured the prevalence and identified the correlates of methamphetamine use amongst current injection drug users (IDUs) in a China-Myanmar border region. METHODS:A cross-sectional survey including interviews and sero...

journal_title：Drug and alcohol dependence

authors： Li L,Assanangkornchai S,Duo L,McNeil E,Li J

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:Boys with serious conduct and substance problems (Antisocial Substance Dependence (ASD)) repeatedly make impulsive and risky decisions in spite of possible negative consequences. Because prefrontal cortex (PFC) is involved in planning behavior in accord with prior rewards and punishments, structural abnormal...

journal_title：Drug and alcohol dependence

authors： Dalwani M,Sakai JT,Mikulich-Gilbertson SK,Tanabe J,Raymond K,McWilliams SK,Thompson LL,Banich MT,Crowley TJ

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that opioid overdose and HIV infection are burgeoning intertwined epidemics among people who inject drugs (PWID) in Central Asia. To date, however, research on overdose and its associations with HIV risks among PWID in Central Asia remains virtually absent. This paper aims to p...

journal_title：Drug and alcohol dependence

authors： Gilbert L,Primbetova S,Nikitin D,Hunt T,Terlikbayeva A,Momenghalibaf A,Ruziev M,El-Bassel N

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have demonstrated gender-related differences in the associations between problem-gambling severity and substance-use disorders; however, these associations have not been examined longitudinally. We aimed to examine the prospective associations between problem-gambling severity and inc...

journal_title：Drug and alcohol dependence

authors： Pilver CE,Libby DJ,Hoff RA,Potenza MN

更新日期：2013-11-01 00:00:00

abstract：:Plasma cyclic AMP levels were determined in a group of 36 male chronic alcoholics during a period of their usual alcohol intake and compared to 29 normal controls. Significantly lower values (P less than 0.005) were found in the patient group. The possible influence of age, chronicity of drinking, family history of al...

journal_title：Drug and alcohol dependence

authors： Lykouras L,Markianos M,Moussas G

更新日期：1988-02-01 00:00:00

abstract：:4-MTA (p-methylthioamphetamine) is a new synthetic sulphur derivative of amphetamine that has been associated with six deaths since it was first identified in Europe in 1997. Sold as 'ecstasy' or 'Flatliners', the drug like MDMA is a potent serotonin releaser. Using a self-nominated sampling methodology we accessed ov...

journal_title：Drug and alcohol dependence

authors： Winstock AR,Wolff K,Ramsey J

更新日期：2002-07-01 00:00:00

abstract：:This paper reports on the results of group therapy for the wives of alcoholics where the alcoholics themselves were offered no treatment. The reason for running such a group is based on the idea that wives might seek help before their husbands, might attend sessions regularly and by acquiring better knowledge of alcoh...

journal_title：Drug and alcohol dependence

authors： Farid B,el Sherbini M,Raistrick D

更新日期：1986-07-01 00:00:00

abstract：:Impulsivity appears to play an important role in suicidal behaviors and drug abuse, which are two psychiatric problems that may interact with one another. Interpretation of the literature on impulsivity in these behaviors may be complicated by the variety of measurement techniques for the assessment of impulsivity. Th...

journal_title：Drug and alcohol dependence

authors： Dougherty DM,Mathias CW,Marsh DM,Moeller FG,Swann AC

更新日期：2004-12-07 00:00:00

abstract：BACKGROUND:Adults with mood and anxiety disorders have an increased likelihood of being prescribed opioids. The influence of other mental disorders, such as psychotic and attention disorders, on opioid prescribing patterns is less known. METHODS:We studied a population-representative sample of 166,927 outpatient visit...

journal_title：Drug and alcohol dependence

authors： Taylor MT,Horton DB,Juliano T,Olfson M,Gerhard T

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Alcohol cues can precipitate the desire to drink and cause relapse in recovering alcohol-dependent patients. Serotonin and dopamine may play a role in alcohol cue-induced craving. Acute combined tryptophan (Trp), tyrosine (Tyr), and phenylalanine (Phe) depletion (CMD) in the diet attenuates the synthesis of ...

journal_title：Drug and alcohol dependence

authors： Sun HQ,Liu Y,Li P,Bao YP,Sheng LX,Zhang RL,Cao YJ,Di XL,Yang FD,Wang F,Luo YX,Lu L

更新日期：2012-08-01 00:00:00

abstract：:A group of adolescent drug "experimenters" as defined by the frequency of use (N = 496) were compared to non-users (N = 2417) and to "regular" users (N = 125) on a number of variables. These covered the patterns of use, attitudes to drug use, exposure to drugs and to drug use, and other behavioural correlates. Experim...

journal_title：Drug and alcohol dependence

authors： Swadi H

更新日期：1990-10-01 00:00:00

abstract：:This study measured effectiveness of behavioral day treatment plus abstinence contingent housing and work therapy (DT+) versus behavioral day treatment alone (DT). A randomized controlled trial assessed participants at baseline, 2 and 6 months. Participants (N=110) met criteria for cocaine abuse or dependence, non-psy...

journal_title：Drug and alcohol dependence

authors： Milby JB,Schumacher JE,McNamara C,Wallace D,Usdan S,McGill T,Michael M

更新日期：2000-07-01 00:00:00

abstract：RATIONALE:Acute doses of buprenorphine can precipitate withdrawal in opioid dependent persons. The likelihood of this withdrawal increases as a function of the level of physical dependence. OBJECTIVES:To test the acute effects of sublingual buprenorphine/naloxone tablets in volunteers with a higher level of physical d...

journal_title：Drug and alcohol dependence

authors： Rosado J,Walsh SL,Bigelow GE,Strain EC

更新日期：2007-10-08 00:00:00

abstract：BACKGROUND:There is some debate whether smoking during pregnancy causes or is only a risk factor for negative academic outcomes and increased risk of psychopathology in offspring. This study evaluated whether maternal smoking cessation would reduce the risk of adverse outcomes in school-aged children. METHODS:Women co...

journal_title：Drug and alcohol dependence

authors： Piper BJ,Gray HM,Birkett MA

更新日期：2012-02-01 00:00:00

abstract：:The relative and combined health effects of cigarette smoking, heroin use, and depression were examined in 322 clinically depressed smokers and 117 opioid-dependent smokers participating in two studies of the San Francisco Treatment Research Center. Opioid-dependent smokers averaged 16 years (S.D.=9) of heroin use; 3%...

journal_title：Drug and alcohol dependence

authors： Prochaska JJ,Sorensen JL,Hall SM,Rossi JS,Redding CA,Rosen AB,Eisendrath SJ,Meisner MR

更新日期：2005-05-09 00:00:00

abstract：:This double-blind, randomized, placebo-controlled clinical trial evaluated the impact on withdrawal symptoms of (i) combining naltrexone with a 4-day buprenorphine taper for short opioid detoxification (NB Group), compared to (ii) using a 4-day buprenorphine taper alone, followed by naltrexone on day 8 (PB Group). Sub...

journal_title：Drug and alcohol dependence

authors： Umbricht A,Montoya ID,Hoover DR,Demuth KL,Chiang CT,Preston KL

更新日期：1999-10-01 00:00:00

abstract：:Research has identified children of alcoholics (COAs) as a population at increased risk for developing substance use problems. Genetic studies support the Al allele of the D2 dopamine receptor gene (DRD2) as a risk marker for alcoholism and substance use disorders. In this study, substance use was assessed in 48 adole...

journal_title：Drug and alcohol dependence

authors： Conner BT,Noble EP,Berman SM,Ozkaragoz T,Ritchie T,Antolin T,Sheen C

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:HIV transmission risk among non-injection drug users is high due to the co-occurrence of drug use and sexual risk behaviors. The purpose of the current study was to identify patterns of drug use among polysubstance users within a high HIV prevalence population. METHODS:The study sample included 409 substanc...

journal_title：Drug and alcohol dependence

authors： Trenz RC,Scherer M,Duncan A,Harrell PT,Moleko AG,Latimer WW

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Reducing underage drinking is a public health priority given increased risk for injury and other consequences. Emergency department (ED) visits offer a potential "teachable moment" to initiate interventions among youth engaged in risky drinking. Given mixed findings for alcohol brief interventions (BIs), thi...

journal_title：Drug and alcohol dependence

authors： Davis AK,Arterberry BJ,Bonar EE,Chermack ST,Blow FC,Cunningham RM,Walton MA

更新日期：2018-07-01 00:00:00

abstract：:Replacement therapy with the synthetic mu-opioid agonist methadone is an efficacious treatment for opioid abuse. While much is known about methadone's pharmacology, its discriminative stimulus properties remain largely unexplored. The present study sought to establish methadone discrimination in rats. Moreover, some r...

journal_title：Drug and alcohol dependence

authors： Vann RE,Wise LE,Varvel SA,Philibin SD,Walentiny DM,Porter JH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Addiction is associated with dorso-lateral prefrontal cortex (DLPFC) dysfunction and altered brain-oscillations. High frequency repetitive transcranial magnetic stimulation (HFrTMS) over DLPFC reportedly reduces drug craving. Its effects on neuropsychological, behavioural and neurophysiological are unclear. ...

journal_title：Drug and alcohol dependence

authors： Del Felice A,Bellamoli E,Formaggio E,Manganotti P,Masiero S,Cuoghi G,Rimondo C,Genetti B,Sperotto M,Corso F,Brunetto G,Bricolo F,Gomma M,Serpelloni G

更新日期：2016-01-01 00:00:00

abstract：:In this paper we estimate the risk of becoming cannabis dependent within 24 months after first use of cannabis and examine subgroup variation in this risk. The study estimates are based on the National Household Survey on Drug Abuse conducted during 2000-2001, with a representative sample of U.S. residents ages 12 and...

journal_title：Drug and alcohol dependence

authors： Chen CY,O'Brien MS,Anthony JC

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Nutrition is a prerequisite for health; yet, there is no special nutritional assessment or guidance for drug and alcohol dependent individuals, despite the fact that their food consumption is often very limited, risking malnutrition. Further, the premise is examined that malnutrition may promote drug seeking...

journal_title：Drug and alcohol dependence

authors： Jeynes KD,Gibson EL

更新日期：2017-10-01 00:00:00