Pyrazole-insensitive alcohol dehydrogenase activity in human serum.

abstract：:The Wide Range Achievement Test (Revised) (WRAT-R) reading test, demographic variables and drug use severity were used to develop prediction equations to estimate premorbid ability in 92 cocaine abusers. WRAT-R reading was correlated significantly with full scale, verbal and performance IQ. Stepwise regression indicat...

journal_title：Drug and alcohol dependence

authors： Ollo C,Lindquist T,Alim TN,Deutsch SI

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Few studies of the natural history of DSM-IV inhalant substance use disorders (I-SUDs) have been conducted. This investigation examined the prevalence, timing, and predictors of transitions from inhalant use to formal I-SUDs among inhalant users within a nationally representative sample. METHODS:Participant...

journal_title：Drug and alcohol dependence

authors： Perron BE,Howard MO,Maitra S,Vaughn MG

更新日期：2009-03-01 00:00:00

abstract：:Working memory (WM) is a major cognitive function that is altered by chronic alcohol consumption. This impairment has been linked to alterations in the hippocampus and prefrontal cortex (PFC). Animal and human studies have shown that the adolescent brain is more sensitive to the neurotoxic effects of alcohol than the ...

journal_title：Drug and alcohol dependence

authors： Crego A,Rodriguez-Holguín S,Parada M,Mota N,Corral M,Cadaveira F

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:In August 2013, a naloxone distribution program was implemented in North Carolina (NC). This study evaluated that program by quantifying the association between the program and county-level opioid overdose death (OOD) rates and conducting a cost-benefit analysis. METHODS:One-group pre-post design. Data incl...

journal_title：Drug and alcohol dependence

authors： Naumann RB,Durrance CP,Ranapurwala SI,Austin AE,Proescholdbell S,Childs R,Marshall SW,Kansagra S,Shanahan ME

更新日期：2019-11-01 00:00:00

abstract：:Olfactory evoked potentials (OEP) were elicited by odorous and nonodorous stimuli in 50 adult subjects: 26 subjects with histories of either cocaine (n = 19) or alcohol (n = 7) dependence, 10 with histories of nicotine but no other drug dependence, 2 with clinical anosmia of peripheral origin, and 12 subjects without ...

journal_title：Drug and alcohol dependence

authors： Bauer LO,Mott AE

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Cannabidiol, a therapeutic with potential serotonin (5-hydroxytryptamine; 5-HT) 5-HT1A receptor agonist activity, is the second most prevalent cannabinoid in Cannabis after Δ(9)-THC. The extent to which cannabidiol modifies the effects of Δ(9)-THC has not been firmly established, especially with respect to a...

journal_title：Drug and alcohol dependence

authors： McMahon LR

更新日期：2016-08-01 00:00:00

abstract：:To explore the mechanisms mediating the effects of acute morphine on the immune system, effects of ganglionic blockade with chlorisondamine on acute high dose morphine-induced alterations in blood lymphocyte proliferation, white blood cell counts, spleen lymphocyte proliferation and splenic natural killer (NK) cell cy...

journal_title：Drug and alcohol dependence

authors： Mellon RD,Bayer BM

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:The implementation of evidence-based practices to reduce opioid overdose deaths within communities remains suboptimal. Community engagement can improve the uptake and sustainability of evidence-based practices. The HEALing Communities Study (HCS) aims to reduce opioid overdose deaths through the Communities ...

journal_title：Drug and alcohol dependence

authors： Sprague Martinez L,Rapkin BD,Young A,Freisthler B,Glasgow L,Hunt T,Salsberry PJ,Oga EA,Bennet-Fallin A,Plouck TJ,Drainoni ML,Freeman PR,Surratt H,Gulley J,Hamilton GA,Bowman P,Roeber CA,El-Bassel N,Battaglia T

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Methamphetamine (MA) abuse is a worldwide problem. Little is known about the co-morbidity of substance use disorders (SUD) and other psychiatric disorders of mothers who use MA prenatally. The Infant Development, Environment and Lifestyle (IDEAL) Study is a prospective, investigation of prenatal MA use and c...

journal_title：Drug and alcohol dependence

authors： Wouldes TA,LaGasse LL,Derauf C,Newman E,Shah R,Smith LM,Arria AM,Huestis MA,DellaGrotta S,Wilcox T,Neal CR Jr,Lester BM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The actions of endogenous opioid peptides are mediated by 3 main classes of opioid receptors; mu (MOR), kappa (KOR), and delta (DOR). METHODS:We developed an absolute quantitative real-time reverse transcriptase PCR (AQ-rt-RT-PCR) assay to quantify MOR, DOR, and KOR mRNA in 22 human tissues. RESULTS:MOR mR...

journal_title：Drug and alcohol dependence

authors： Peng J,Sarkar S,Chang SL

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:In Mexico, the Northern States are highly impacted by alcohol consumption and associated problems. Little is known about the association between contextual social disadvantage and alcohol use disorder in this region. METHODS:Information from 1265 current drinkers surveyed in the U.S.-Mexico Study on Alcohol...

journal_title：Drug and alcohol dependence

authors： Orozco R,Benjet C,Ruiz Velasco-Acosta S,Moreno Altamirano L,Karriker-Jaffe KJ,Zemore S,Cherpitel C,Borges G

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Although prenatal cocaine exposure (PCE) has been linked with greater externalizing behavior, no studies have investigated heterogeneity of developmental trajectories in children with PCE to date. The present study aimed to: (1) identify developmental trajectories of externalizing problems in childhood by us...

journal_title：Drug and alcohol dependence

authors： Min MO,Minnes S,Park H,Ridenour T,Kim JY,Yoon M,Singer LT

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The theoretical benefits of naltrexone as a treatment for opioid use disorder (e.g., safety, non-addictive, low risk of diversion) stand in sharp contrast to its disappointing record on retention in most samples. The relationship of uncomfortable physical and dysphoric symptoms to retention on naltrexone is ...

journal_title：Drug and alcohol dependence

authors： Carroll KM,Nich C,Frankforter TL,Yip SW,Kiluk BD,DeVito EE,Sofuoglu M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Stressful life events (SLEs) play a key role in suicidal behavior among adults with alcohol use disorders (AUD), yet there are meager data on the severity of SLEs preceding suicidal behavior or the timing of such events. METHOD:Patients in residential substance use treatment who made a recent suicide attemp...

journal_title：Drug and alcohol dependence

authors： Conner KR,Houston RJ,Swogger MT,Conwell Y,You S,He H,Gamble SA,Watts A,Duberstein PR

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:There is concern that recreational marijuana legalization (RML) may lead to increased cannabis use disorder (CUD) among youth due to increased marijuana use. This study investigates whether adolescent substance use disorder treatment admissions for marijuana use increased in Colorado and Washington followi...

journal_title：Drug and alcohol dependence

authors： Mennis J,Stahler GJ

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:This study assessed whether the Nationwide Emergency Department Sample (NEDS) could reliably fill the national drug surveillance gap caused by the discontinuation of the Drug Abuse Warning Network (DAWN). METHODS:Estimates of the drug-related emergency department (ED) visits derived from DAWN (2004-2011) an...

journal_title：Drug and alcohol dependence

authors： Sevigny EL,Caces MF

更新日期：2018-11-01 00:00:00

abstract：AIMS:The primary aim of the present study is to determine the one year periodic prevalence of dispension of different analgesics to patients in long term opioid maintenance therapy (OMT). The secondary aim is to determine to which extent non-opioid analgesics are used as first line analgesics. DESIGN:The study is a ph...

journal_title：Drug and alcohol dependence

authors： Fredheim OM,Borchgrevink PC,Nordstrand B,Clausen T,Skurtveit S

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To determine the patterns of acquisitive crime during methadone maintenance treatment among chronic, treatment-resistant heroin users eligible for heroin assisted treatment in the Netherlands. METHODS:We retrospectively assessed the type and number of illegal activities during 1 month of standard methadone m...

journal_title：Drug and alcohol dependence

authors： van der Zanden BP,Dijkgraaf MG,Blanken P,van Ree JM,van den Brink W

更新日期：2007-01-05 00:00:00

abstract：:The purpose of this study was to determine if a modified version of the Contemplation Ladder, a measure of motivation to change marijuana use among incarcerated adolescents (Marijuana Ladder; ML), was related to marijuana use and treatment engagement. Participants (N=122) in this study were all incarcerated at a state...

journal_title：Drug and alcohol dependence

authors： Slavet JD,Stein LA,Colby SM,Barnett NP,Monti PM,Golembeske C Jr,Lebeau-Craven R

更新日期：2006-06-09 00:00:00

abstract：BACKGROUND:Little is known about the sequence of onsets in patients affected by comorbid alcohol use and bipolar disorder. This study examines the risk factors associated with their co-occurrence and order of onset. METHOD:The demographic, clinical, and temperament characteristics as well as the course of illness were...

journal_title：Drug and alcohol dependence

authors： Azorin JM,Perret LC,Fakra E,Tassy S,Simon N,Adida M,Belzeaux R

更新日期：2017-10-01 00:00:00

abstract：:In a therapeutic workplace business, drug abuse patients are hired as data entry operators and paid to perform data entry work contingent upon documented drug abstinence. Reliable attendance has been difficult to maintain despite the opportunity for operators to earn a living wage, 6 h per day, 5 days per week. A with...

journal_title：Drug and alcohol dependence

authors： Wong CJ,Dillon EM,Sylvest C,Silverman K

更新日期：2004-06-11 00:00:00

abstract：:Exposure to self-administered drugs is sufficient to produce drug-seeking in animal models. In many cases priming injections of drugs that share discriminative stimulus properties with the self-administered drug also can lead to drug-seeking, suggesting that exposure might precipitate relapse. The present investigatio...

journal_title：Drug and alcohol dependence

authors： Schenk S,Hely L,Gittings D,Lake B,Daniela E

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Drug addiction researchers have begun to study dopamine partial agonists as potential therapeutic agents. The partial dopamine D(2) receptor agonist aripiprazole has recently been tested as a treatment for stimulant and alcohol dependence in both animal and clinical studies. METHODS:A randomized and placebo...

journal_title：Drug and alcohol dependence

authors： Liu Y,Sun HQ,Bao YP,Li SX,Beveridge TJ,Di XL,Yang FD,Lu L

更新日期：2009-04-01 00:00:00

abstract：:Intranasal cocaine (COC) and oral ethanol (ETOH) were administered to one group of seven research volunteers during daily experimental sessions. Following the determination of baseline subjective and performance measures, an ETOH cocktail (0, 19.4, 38.7 or 58.1 g of ETOH in lemonade) was consumed over a 10-min period....

journal_title：Drug and alcohol dependence

authors： Foltin RW,Fischman MW,Pippen PA,Kelly TH

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:We examined the effects of baseline drug use and dependence on alcohol use outcomes following brief motivational intervention for at-risk drinking (BMI-ETOH). METHODS:HLM models were developed to test the interaction of drug use and dependence with BMI-ETOH for alcohol use among Hispanic (n=539), Caucasian ...

journal_title：Drug and alcohol dependence

authors： Field CA,Cochran G,Caetano R

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Executive dysfunction is common in substance use disorder (SUD) populations and hinders treatment. We previously found that 50% of residents in SUD therapeutic communities had been hospitalized for head injuries; this was a significant determinant of cognitive impairment. The current study aimed to establish...

journal_title：Drug and alcohol dependence

authors： Marceau EM,Berry J,Lunn J,Kelly PJ,Solowij N

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Both cannabis use and alcohol use are elevated among people living with HIV, but few studies have investigated the relationship between cannabis use and alcohol use in this population. This study examined the longitudinal association between cannabis use and alcohol use among people living with HIV and explo...

journal_title：Drug and alcohol dependence

authors： Wardell JD,Shuper PA,Hendershot CS

更新日期：2018-12-01 00:00:00

abstract：:Premature termination of treatment by the client has been a pervasive problem in the alcohol treatment field. This drop-out problem is compounded in conjoint therapy for alcoholic couples since most clients typically do not view the drinking problem from a systemic, interactional perspective. Within a short-term commu...

journal_title：Drug and alcohol dependence

authors： Zweben A,Pearlman S,Li S

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:The present study examined (1) the association between changes in perceived parental control and support from age 13 to 15 and early onset of cannabis use (before age 16), and (2) whether personality modifies the association between a decline in perceived parental control and support and early onset of canna...

journal_title：Drug and alcohol dependence

authors： Creemers HE,Buil JM,van Lier PA,Keijsers L,Meeus W,Koot HM,Huizink AC

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Healthcare professionals are crucial in the identification and accessibility to treatment for people with substance use disorders. Our objective was to assess health professionals' attitudes towards patients with substance use disorders and examine the consequences of these attitudes on healthcare delivery f...

journal_title：Drug and alcohol dependence

authors： van Boekel LC,Brouwers EP,van Weeghel J,Garretsen HF

更新日期：2013-07-01 00:00:00