When DAWN went dark: Can the Nationwide Emergency Department Sample (NEDS) fill the surveillance gap left by the discontinued Drug Abuse Warning Network (DAWN)?


BACKGROUND:This study assessed whether the Nationwide Emergency Department Sample (NEDS) could reliably fill the national drug surveillance gap caused by the discontinuation of the Drug Abuse Warning Network (DAWN). METHODS:Estimates of the drug-related emergency department (ED) visits derived from DAWN (2004-2011) and NEDS (2006-2013). Estimates of the underlying reason for the drug-related ED visit, patient characteristics, and the specific drugs involved were compared for 2011, the most recent overlapping data year in DAWN and NEDS. Trends in ED visits for major drugs of abuse were then compared over the period 2004-2013. RESULTS:In 2011, DAWN and NEDS produced statistically similar estimates of the overall number of drug-related ED visits (5.1 vs. 4.9 million) and those involving drug misuse or abuse (2.65 vs. 2.77 million). Among the latter, estimates by gender, age group, and patient disposition were generally consistent across data systems, suggesting that NEDS and DAWN samples draw from a similar population. Main analyses reveal statistically similar estimates across data systems in both levels and trends for cocaine, amphetamines, and narcotic pain relievers. In contrast, the number of ED visits for sedatives and heroin was significantly undercounted in NEDS, whereas marijuana-related ED visits were undercounted in DAWN. CONCLUSIONS:This study demonstrates the utility of NEDS for conducting post-DAWN drug surveillance. Because NEDS cannot provide targeted surveillance of certain established (e.g., heroin) and emerging (e.g., fentanyl) drugs, however, it is critical that a data system that employs medical record-based reviews be implemented to augment the known weaknesses of NEDS.


Drug Alcohol Depend


Sevigny EL,Caces MF




Has Abstract


2018-11-01 00:00:00












  • Smokeless tobacco brand switching: a means to reduce toxicant exposure?

    abstract::The purpose of this study was to examine the effects of smokeless tobacco (ST) brand switching on biomarkers of ST exposure and on ST use. Subjects seeking treatment to reduce their use were randomized to ST brand switching with controlled ST topography, brand switching with ad libitum ST use, or a waitlist control wi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: Hatsukami DK,Ebbert JO,Anderson A,Lin H,Le C,Hecht SS

    更新日期:2007-03-16 00:00:00

  • Efficacy of the Community Reinforcement and Family Training for concerned significant others of treatment-refusing individuals with alcohol dependence: A randomized controlled trial.

    abstract:BACKGROUND:The Community Reinforcement and Family Training (CRAFT) is a promising approach for Concerned Significant Others (CSOs) of alcohol-dependent individuals (ADI) that aims to engage treatment-refusing patients in alcohol treatment and to improve CSO functioning. To date, only two randomized controlled trials (R...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: Bischof G,Iwen J,Freyer-Adam J,Rumpf HJ

    更新日期:2016-06-01 00:00:00

  • The changes in sulfhydryl compounds in plasma, liver and brain after acute and chronic ethanol administration in rats.

    abstract::The content of sulfhydryl compounds in proteins and non-proteins of plasma, liver and brain after acute and chronic ethanol administration was investigated in rats. After ethanol ingestion for 4 weeks (6 g/kg, day 30% w/v) significant changes were observed in plasma proteins and in liver proteins and non-proteins. In ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Farbiszewski R,Holownia A,Chwiecko M

    更新日期:1987-11-01 00:00:00

  • Trusting the source: The potential role of drug dealers in reducing drug-related harms via drug checking.

    abstract:OBJECTIVES:Drug checking technologies (DCTs) have been implemented as a response to the ongoing opioid overdose epidemic. We examined the level of trust people who use drugs (PWUD) have in their drug dealers as well as their perspectives on the potential for drug dealers to use DCTs to provide knowledge of drug content...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Bardwell G,Boyd J,Arredondo J,McNeil R,Kerr T

    更新日期:2019-05-01 00:00:00

  • Initiation into methamphetamine use for young gay and bisexual men.

    abstract::Research over the past 10 years has suggested that methamphetamine use has become a significant problem and is associated with risky sexual behaviors among gay and bisexual men. In order to better understand initiation into methamphetamine use among gay and bisexual men, qualitative analyses were performed on a sample...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Parsons JT,Kelly BC,Weiser JD

    更新日期:2007-10-08 00:00:00

  • Resting state synchrony in long-term abstinent alcoholics with versus without comorbid drug dependence.

    abstract:BACKGROUND:We previously reported that when long-term abstinent alcoholics (LTAA; with no drug comorbidity) are compared to controls, they show increased resting state synchrony (RSS) in the executive control network and reduced RSS in the appetitive drive network suggestive of compensatory mechanisms that may facilita...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Camchong J,Stenger VA,Fein G

    更新日期:2013-07-01 00:00:00

  • ART uptake and adherence among women who use drugs globally: A scoping review.

    abstract:OBJECTIVE:To assess the state of peer-reviewed literature surrounding uptake and adherence of antiretroviral therapy (ART) among HIV-positive women who use drugs (WWUD). METHODS:Consistent with PRISMA-ScR guidelines, we conducted a scoping literature review on ART uptake and adherence among WWUD, searching PubMed, Emb...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,评审


    authors: Glick JL,Huang A,Russo R,Jivapong B,Ramasamy V,Rosman L,Pelaez D,Footer KHA,Sherman SG

    更新日期:2020-10-01 00:00:00

  • Prolactin and thyrotropin pituitary response to thyrotropin releasing hormone in young female heroin addicts.

    abstract::Prolactin (PRL) and thyrotropin (TSH) serum levels were determined in a group of young female heroin addicts treated in hospital with methadone in tapered doses. At admission, from 24 to 3 h after the last dose of 'street' heroin, basal PRL values were 21 +/- 2.6 ng/ml, i.e. significantly higher (P less than 0.001) th...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Spagnolli W,De Venuto G,Mattarei M,Dal Ri P,Miori R

    更新日期:1987-11-30 00:00:00

  • Higher pretreatment blood pressure is associated with greater alcohol drinking reduction in alcohol-dependent individuals treated with doxazosin.

    abstract:BACKGROUND:Preclinical and clinical research suggest that the α1 receptor antagonist prazosin reduces alcohol consumption. Furthermore, clinical studies indicate a role for prazosin in treating Post-Traumatic Stress Disorder (PTSD) symptoms and a recent trial suggested that pre-treatment blood pressure (BP) predicts th...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: Haass-Koffler CL,Goodyear K,Zywiak WH,Magill M,Eltinge SE,Wallace PM,Long VM,Jayaram-Lindström N,Swift RM,Kenna GA,Leggio L

    更新日期:2017-08-01 00:00:00

  • Baclofen administration for the treatment of affective disorders in alcoholic patients.

    abstract::Ninety alcoholic patients with the secondary affective disorders (anxiety, depression) were divided into four groups. Patients in the first group received GABAB receptor ligands (baclofen), those in the second group, diazepam, those in the third group, amitriptyline and those in the fourth group, placebo. The results ...

    journal_title:Drug and alcohol dependence

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Krupitsky EM,Burakov AM,Ivanov VB,Krandashova GF,Lapin IP,Grinenko AJa,Borodkin YuS

    更新日期:1993-09-01 00:00:00

  • Protective behavioral strategies predict alcohol-related problems among injured patients following a brief intervention.

    abstract:BACKGROUND:Alcohol protective behavioral strategies (PBS) have been proposed as mechanisms of change underlying interventions for reducing alcohol use and alcohol-related problems. Few studies have examined PBS use among non-college student populations and no study has examined PBS use among adult injured patients. The...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Richards DK,Pearson MR,Morera OF,Field CA

    更新日期:2019-12-01 00:00:00

  • Early onset of cannabis use: does personality modify the relation with changes in perceived parental involvement?

    abstract:BACKGROUND:The present study examined (1) the association between changes in perceived parental control and support from age 13 to 15 and early onset of cannabis use (before age 16), and (2) whether personality modifies the association between a decline in perceived parental control and support and early onset of canna...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Creemers HE,Buil JM,van Lier PA,Keijsers L,Meeus W,Koot HM,Huizink AC

    更新日期:2015-01-01 00:00:00

  • Evaluation of a brief intervention to reduce the negative consequences of drug misuse among adult emergency department patients.

    abstract:OBJECTIVES:Determine if a brief intervention (BI) reduces the negative consequences of drug use/misuse among adult emergency department (ED) patients, and identify patients more likely to benefit from the BI. METHODS:This randomized, controlled trial enrolled 1026 18-64 year-old ED patients whose drug misuse indicated...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验


    authors: Guan W,Liu T,Baird JR,Merchant RC

    更新日期:2015-12-01 00:00:00

  • Effects of priming injections of MDMA and cocaine on reinstatement of MDMA- and cocaine-seeking in rats.

    abstract::Exposure to self-administered drugs is sufficient to produce drug-seeking in animal models. In many cases priming injections of drugs that share discriminative stimulus properties with the self-administered drug also can lead to drug-seeking, suggesting that exposure might precipitate relapse. The present investigatio...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Schenk S,Hely L,Gittings D,Lake B,Daniela E

    更新日期:2008-08-01 00:00:00

  • Historical trends in the grade of onset and sequence of cigarette, alcohol, and marijuana use among adolescents from 1976-2016: Implications for "Gateway" patterns in adolescence.

    abstract:INTRODUCTION:In the past decade, marijuana use prevalence among adolescents has remained relatively steady while cigarette and alcohol prevalence has declined. We examined historical trends in: average grade of onset of marijuana, alcohol, and cigarette use by 12th grade; proportion who try alcohol/cigarettes before fi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Keyes KM,Rutherford C,Miech R

    更新日期:2019-01-01 00:00:00

  • Concurrent treatment for alcohol and tobacco dependence: are patients ready to quit both?

    abstract::The prevalence of smoking among alcohol abusers is high, yet little is known about this dual-dependency. This study examines mechanisms involved in changing both alcohol and tobacco use concurrently using the transtheoretical model (TTM) measures of change. Alcohol and tobacco dependent outpatients (N=115) entering a ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Stotts AL,Schmitz JM,Grabowski J

    更新日期:2003-01-24 00:00:00

  • Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats.

    abstract:BACKGROUND:Kratom (Mitragyna speciosa Korth.) has been used in Southeast Asia for hundreds of years to increase energy, for relaxation, and to diminish opioid withdrawal. Kratom use has recently spread to Western countries. Kratom could potentially be used for the treatment of opioid withdrawal and pain, but more insig...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Behnood-Rod A,Chellian R,Wilson R,Hiranita T,Sharma A,Leon F,McCurdy CR,McMahon LR,Bruijnzeel AW

    更新日期:2020-10-01 00:00:00

  • Sites of action of naloxone in precipitating withdrawal jumping in morphine-dependent mice: investigations by the ED50 value and CNS content of naloxone.

    abstract::The sites of action of naloxone and the possible interaction between supraspinally and spinally administered naloxone in precipitating withdrawal jumping were investigated by comparing the ED50 value and central nervous system (CNS) content of naloxone after three different administration routes in morphine-dependent ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Miyamoto Y,Takemori AE

    更新日期:1993-04-01 00:00:00

  • The two-faceted nature of impulsivity in patients with borderline personality disorder and substance use disorder.

    abstract:BACKGROUND:Impulsivity, which has been the subject of extensive debate in psychiatric research, is a clinically important concept, especially with respect to Borderline Personality Disorder (BPD) and Substance Use Disorders (SUD). The current study aims to examine the presence of two aspects of impulsivity (self-report...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Maraz A,Andó B,Rigó P,Harmatta J,Takách G,Zalka Z,Boncz I,Lackó Z,Urbán R,van den Brink W,Demetrovics Z

    更新日期:2016-06-01 00:00:00

  • Genetic factors in substance abuse based on studies of Tourette syndrome and ADHD probands and relatives. I. Drug abuse.

    abstract::There have been relatively few studies of genetic factors in drug abuse. Childhood Attention Deficit Hyperactivity Disorder (ADHD) has been implicated as a risk factor, and pedigree studies of Tourette Syndrome (TS), a hereditary impulse disorder closely related to ADHD, show an increased prevalence of substance abuse...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Comings DE

    更新日期:1994-03-01 00:00:00

  • Marijuana use trajectories during the post-college transition: health outcomes in young adulthood.

    abstract:BACKGROUND:Despite the relatively high prevalence of marijuana use among college students, little information exists regarding health outcomes associated with different use patterns or trajectories. METHODS:Seven annual personal interviews (years 1-7) were administered to 1253 individuals, beginning in their first yea...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Caldeira KM,O'Grady KE,Vincent KB,Arria AM

    更新日期:2012-10-01 00:00:00

  • Generalised inhibitory impairment to appetitive cues: From alcoholic to non-alcoholic visual stimuli.

    abstract:BACKGROUND:Prior research demonstrates that individuals who consume alcohol show diminished inhibitory control towards alcohol-related cues. However, such research contrasts predominantly alcoholic appetitive cues with non-alcoholic, non-appetitive cues (e.g., stationary items). As such, it is not clear whether it is s...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Monk RL,Qureshi A,Pennington CR,Hamlin I

    更新日期:2017-11-01 00:00:00

  • Attention and memory in illicit amphetamine users: comparison with non-drug-using controls.

    abstract::The purpose of this study was to clarify the extent of neuropsychological impairment previously found among amphetamine users (McKetin and Mattick, 1997) by comparing them with a non-drug-using control group. Amphetamine users who were classified as low dependence (n = 15) or high dependence (n = 11) according to the ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: McKetin R,Mattick RP

    更新日期:1998-04-01 00:00:00

  • High HIV prevalence and risk factors among injection drug users in Tashkent, Uzbekistan, 2003-2004.

    abstract:OBJECTIVES:To determine HIV prevalence and potential associations with sociodemographic and behavioral factors among injection drug users (IDUs) in Tashkent, Uzbekistan. METHODS:Subjects in this cross-sectional study provided sociodemographic and risk behavior data and were tested for HIV antibody with a saliva-based ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Sanchez JL,Todd CS,Bautista CT,Botros BA,Khakimov MM,Giyasova GM,Yakubov SK,Abdulaeva MA,Saad MD,Graham RR,Carr JK,Earhart KC

    更新日期:2006-04-01 00:00:00

  • Precursors to heroin: a pilot study of young heroin addicts and their nonaddicted friends.

    abstract::To determine whether differences in life styles and patterns of drug use may help to account for willingness to try heroin and/or likelihood of becoming addicted, personal history interviews were conducted with 15 young heroin addict, 15 experimenters who used the drug but did not become addicts, and 15 nonusers who n...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Crawford GA

    更新日期:1978-05-01 00:00:00

  • Characteristics and circumstances of death related to new psychoactive stimulants and hallucinogens in Australia.

    abstract:BACKGROUND:New psychoactive stimulants and hallucinogens comprise a range of "designer drugs" that have risen to prominence in the 21st century. The study aimed to: 1. Determine the characteristics, and circumstances of death, of all recorded cases of new psychoactive stimulant and hallucinogen-related death in Austral...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Darke S,Duflou J,Peacock A,Farrell M,Lappin J

    更新日期:2019-11-01 00:00:00

  • Predictors of follow-up health status in the Drug Abuse Treatment Outcome Study (DATOS).

    abstract::This study examined the predictors of self-reported health status at follow-up in the Drug Abuse Treatment Outcomes Study (DATOS), a longitudinal study of drug abuse treatment programs and patients in 1991-1993. Baseline and follow-up interviews of 2966 patients in 75 programs were performed. The follow-up assessment ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Friedmann PD,Lemon SC,Anderson BJ,Stein MD,Drug Abuse Treatment Outcome Study (DATOS.

    更新日期:2003-04-01 00:00:00

  • Short-term stability of different drinking patterns over the course of four weeks among adults. A latent transition analysis.

    abstract:OBJECTIVE:The purpose of the present study was to identify drinking patterns and determine their intraindividual stability over the course of four weeks among a sample of adults from the general population. METHODS:The sample comprised 288 adults who reported drinking alcohol at least once per month (49% female; mean ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Staudt A,Freyer-Adam J,Meyer C,John U,Baumann S

    更新日期:2018-10-01 00:00:00

  • Introduction to the College on Problems of Drug Dependence special issue: contemporary advances in opioid neuropharmacology.

    abstract::Opioid receptors are critical therapeutic targets for medications development relevant to the treatment of drug dependence and pain. With recent advances in molecular neurobiology, it has become evident that the functional activity of opioid receptors, as ligand-regulated protein complexes, is modulated by multifariou...

    journal_title:Drug and alcohol dependence

    pub_type: 社论


    authors: Walsh SL,Unterwald EM,Izenwasser S

    更新日期:2010-05-01 00:00:00

  • Comparison of urinary 5-hydroxytryptophol, breath ethanol, and self-report for detection of recent alcohol use during outpatient treatment: a study on methadone patients.

    abstract::This study compared urinary 5-hydroxytryptophol (5HTOL) with breath-ethanol testing as objective ways to disclose recent drinking by outpatients attending a methadone maintenance treatment clinic. Information about quantity and frequency of alcohol use was obtained by confidential self-reports. Random screening was pe...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章


    authors: Helander A,von Wachenfeldt J,Hiltunen A,Beck O,Liljeberg P,Borg S

    更新日期:1999-08-02 00:00:00