Influences on adolescent substance dependence: conduct disorder, depression, attention deficit hyperactivity disorder, and gender.

Abstract:

OBJECTIVE:In adolescents, conduct disorder (CD), attention deficit hyperactivity disorder (ADHD), and depression are frequently comorbid with substance dependence (SD). We hypothesized that the prevalence and severity of CD, major depressive disorder (MDD), and ADHD would differ by gender, and that these conditions would associate differentially with severity of SD in males and females. METHODS:We examined these issues, using standardized diagnostic interviews, in 285 male and 82 female adolescents referred for comorbid CD and SD. RESULTS:Males and females did not differ significantly in severity of substance involvement, MDD, or ADHD, but males had more severe CD. MDD severity was the only variable significantly associated with SD severity for females, while for males, severity of CD combined with MDD and ADHD was significantly associated with SD severity. CONCLUSIONS:Among referred adolescents, CD, MDD, and ADHD may all be important concomitants of SD in males, while in females, depression may be the primary variable related to SD.

journal_name

Drug Alcohol Depend

authors

Whitmore EA,Mikulich SK,Thompson LL,Riggs PD,Aarons GA,Crowley TJ

doi

10.1016/s0376-8716(97)00074-4

subject

Has Abstract

pub_date

1997-08-25 00:00:00

pages

87-97

issue

2

eissn

0376-8716

issn

1879-0046

pii

S0376871697000744

journal_volume

47

pub_type

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