Cognitive remediation improves executive functions, self-regulation and quality of life in residents of a substance use disorder therapeutic community.

Abstract:

BACKGROUND:Executive dysfunction is common in substance use disorder (SUD) populations and hinders treatment. We previously found that 50% of residents in SUD therapeutic communities had been hospitalized for head injuries; this was a significant determinant of cognitive impairment. The current study aimed to establish whether cognitive remediation improves executive functions (EFs) and self-regulation in an ecologically valid sample of female residents attending SUD therapeutic community treatment, including those with past head injuries and psychiatric comorbidities. METHODS:Controlled sequential groups design with residents (N=33, all female) receiving treatment as usual (TAU). The intervention group (n=16) completed four weeks of cognitive remediation (CR) and the control, TAU only (n=17). Outcome measures assessed pre- and post-intervention included both performance- and inventory-based measures of EFs, and self-reported self-regulation and quality of life. RESULTS:CR relative to TAU significantly improved performance-based assessment of inhibition (Color-Word Interference Test; F=4.29, p=0.047), inventory-based assessment of EFs (Behavior Rating Inventory of Executive Function - Adult Version: Global Executive Composite; F=6.38, p=0.017), impulsivity (Barratt Impulsiveness Scale; F=4.61, p=0.040), self-control (Brief Self-Control Scale; F=5.53, p=0.026), and quality of life (Quality of Life Enjoyment and Satisfaction Questionnaire - Short Form; F=7.68, p=0.010). CONCLUSIONS:Findings suggest that CR improves EFs in a heterogeneous sample of female residents in therapeutic community SUD treatment. Future research may explore the possibility of tailoring CR interventions for various SUD subgroups.

journal_name

Drug Alcohol Depend

authors

Marceau EM,Berry J,Lunn J,Kelly PJ,Solowij N

doi

10.1016/j.drugalcdep.2017.04.023

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

150-158

eissn

0376-8716

issn

1879-0046

pii

S0376-8716(17)30265-X

journal_volume

178

pub_type

杂志文章
  • Perceived discrimination in addiction recovery: Assessing the prevalence, nature, and correlates using a novel measure in a U.S. National sample.

    abstract:BACKGROUND:Alcohol and other drug (AOD) problems are among the most stigmatized conditions globally diminishing help-seeking due to fear of discrimination. Discrimination is common also among people already in AOD recovery, but little is known about the prevalence and nature of perceived discrimination. Greater knowled...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.107667

    authors: Vilsaint CL,Hoffman LA,Kelly JF

    更新日期:2020-01-01 00:00:00

  • Age trends in alcohol use behavior patterns among U.S. adults ages 18-65.

    abstract:INTRODUCTION:Although much of the work on risky alcohol use behaviors, such as heavy drinking, focuses on adolescence and young adulthood, these behaviors are associated with negative health consequences across all ages. Existing studies on age trends have focused on a single alcohol use behavior across many ages, usin...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.107689

    authors: Bray BC,Dziak JJ,Lanza ST

    更新日期:2019-12-01 00:00:00

  • Predictors of positive drinking outcomes among youth receiving an alcohol brief intervention in the emergency department.

    abstract:BACKGROUND:Reducing underage drinking is a public health priority given increased risk for injury and other consequences. Emergency department (ED) visits offer a potential "teachable moment" to initiate interventions among youth engaged in risky drinking. Given mixed findings for alcohol brief interventions (BIs), thi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2018.03.044

    authors: Davis AK,Arterberry BJ,Bonar EE,Chermack ST,Blow FC,Cunningham RM,Walton MA

    更新日期:2018-07-01 00:00:00

  • Transdermal nicotine alters some of marihuana's effects in male and female volunteers.

    abstract::Despite the fact that tobacco and marihuana are often used together, relatively little is known about the effects of this combination. In order to investigate the effects of the principal psychoactive component in tobacco smoke, nicotine, on marihuana-induced intoxication, we conducted a double blind, cross-over exper...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2005.01.008

    authors: Penetar DM,Kouri EM,Gross MM,McCarthy EM,Rhee CK,Peters EN,Lukas SE

    更新日期:2005-08-01 00:00:00

  • Epidemiologic trends and geographic patterns of fatal opioid intoxications in Connecticut, USA: 1997-2007.

    abstract:BACKGROUND:The leading cause of injury death among adults in Connecticut (CT), USA is drug poisonings. We analyzed the epidemiology and geographic distribution of opioid-involved accidental drug-involved intoxication deaths ("overdoses") in CT over an 11-year period. METHODS:We reviewed data from 1997 to 2007 on all a...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2010.11.007

    authors: Green TC,Grau LE,Carver HW,Kinzly M,Heimer R

    更新日期:2011-06-01 00:00:00

  • Cotinine replacement levels for a 21 mg/day transdermal nicotine patch in an outpatient treatment setting.

    abstract::This study examined plasma cotinine replacement levels of 56 outpatient smokers administered a 21 mg/day transdermal nicotine patch (Nicoderm CQ ). The percentage of cotinine replacement ranged from 35 to 232% (mean 107%; median 90.5%). Four subject variables were found to be significantly correlated with percentage o...

    journal_title:Drug and alcohol dependence

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0376-8716(98)00163-x

    authors: Gariti P,Alterman AI,Barber W,Bedi N,Luck G,Cnaan A

    更新日期:1999-04-01 00:00:00

  • Cocaine use disorders and suicidal ideation.

    abstract::The goal of this study was to determine the contribution of substance abuse to the expression of suicidal ideation in a sample of patients referred for evaluation of chemical dependency in a large urban Psychiatric Emergency Service (PES). Records from 777 consecutive patients referred to the chemical dependency servi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/s0376-8716(02)00337-x

    authors: Garlow SJ,Purselle D,D'Orio B

    更新日期:2003-05-01 00:00:00

  • Prevalence and correlates of waterpipe tobacco smoking by college students in North Carolina.

    abstract:BACKGROUND:Known most commonly in the U.S. as "hookah," waterpipe tobacco smoking appears to be growing among college students. Despite beliefs that waterpipe use is safer than cigarette smoking, research to date (albeit limited) has found health risks of waterpipe smoking are similar to those associated with cigarette...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.drugalcdep.2011.01.018

    authors: Sutfin EL,McCoy TP,Reboussin BA,Wagoner KG,Spangler J,Wolfson M

    更新日期:2011-05-01 00:00:00

  • A review of alcohol's effects on sex and reproduction.

    abstract::Alcohol increases libido, inhibits sexual physiological responses and adversely affects reproductive processes in men and women. The mechanisms that underlie these effects are examined and the implications of these effects are discussed. ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,评审

    doi:10.1016/0376-8716(80)90158-1

    authors: Abel EL

    更新日期:1980-05-01 00:00:00

  • Platelet monoamine oxidase and erythrocyte catechol-o-methyltransferase activity in alcoholism and controlled abstinence.

    abstract::This study substantiates previous reports that low platelet monoamine oxidase (MAO) activity is associated with alcoholism. Catechol-o-methyltransferase (COMT) activity in erythrocytes of alcoholics did not differ from that of controls. In 20 male alcoholics low platelet MAO activity was found during the first 3 days ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(83)90056-x

    authors: Agarwal DP,Philippu G,Milech U,Ziemsen B,Schrappe O,Goedde HW

    更新日期:1983-08-01 00:00:00

  • Poly-club-drug use among gay and bisexual men: a longitudinal analysis.

    abstract:OBJECTIVE:We sought to delineate patterns of poly-club-drug use among gay and bisexual men. Data were drawn from a large-scale 12-month longitudinal investigation of club drug use and sexual behavior among 450 racially, ethnically, and geographically diverse sample of gay and bisexual men in New York City. METHODS:Usi...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2006.12.028

    authors: Halkitis PN,Palamar JJ,Mukherjee PP

    更新日期:2007-07-10 00:00:00

  • JUUL electronic cigarettes: Nicotine exposure and the user experience.

    abstract:BACKGROUND:As of March 2019, JUUL electronic cigarettes are the most popular e-cigarette on the U.S. market, but little is known of nicotine exposure and dependence on JUUL and user experience. METHODS:JUUL users participated in a community-based study involving questionnaires, saliva collection and a qualitative inte...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.05.019

    authors: Nardone N,Helen GS,Addo N,Meighan S,Benowitz NL

    更新日期:2019-10-01 00:00:00

  • Exposure to the Lebanon War of 2006 and effects on alcohol use disorders: the moderating role of childhood maltreatment.

    abstract:BACKGROUND:Civilian populations now comprise the majority of casualties in modern warfare, but effects of war exposure on alcohol disorders in the general population are largely unexplored. Accumulating literature indicates that adverse experiences early in life sensitize individuals to increased alcohol problems after...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2013.10.014

    authors: Keyes KM,Shmulewitz D,Greenstein E,McLaughlin K,Wall M,Aharonovich E,Weizman A,Frisch A,Spivak B,Grant BF,Hasin D

    更新日期:2014-01-01 00:00:00

  • Barriers to seeking help for physicians with substance use disorder: A review.

    abstract:BACKGROUND:Substance use disorders (SUD) might concern as many as 8-15% of physicians. Previous studies suggest that self-diagnosis and self-medication are common practices among physicians. The aim of this review was to identify if barriers to seeking help and medical care for impaired physicians exist. We also aimed ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,评审

    doi:10.1016/j.drugalcdep.2019.04.004

    authors: Vayr F,Herin F,Jullian B,Soulat JM,Franchitto N

    更新日期:2019-06-01 00:00:00

  • Prescription drug misuse among homeless youth.

    abstract:BACKGROUND:Prescription drug misuse (PDM) is highly prevalent among youth in the U.S., and can have serious health consequences. Homeless youth are a particularly vulnerable population with high rates of substance use. However, PDM has not been studied in a sample comprised exclusively of homeless youth. METHODS:A sam...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2014.02.011

    authors: Rhoades H,Winetrobe H,Rice E

    更新日期:2014-05-01 00:00:00

  • The temporal relationship between per capita alcohol consumption and harm: a systematic review of time lag specifications in aggregate time series analyses.

    abstract:BACKGROUND:Changes in per capita alcohol consumption are temporally linked to changes in rates of alcohol-related harm. Methodological approaches for analysing this relationship have been suggested, however, the problem of time lags is not well-addressed. This study provides a review of time lag specifications, looking...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.drugalcdep.2011.12.005

    authors: Holmes J,Meier PS,Booth A,Guo Y,Brennan A

    更新日期:2012-06-01 00:00:00

  • Individual-level syringe coverage among Needle and Syringe Program attendees in Australia.

    abstract:BACKGROUND:Harm associated with injecting drug use is a significant public health issue and a major cause of morbidity and mortality, with global estimates of 3 million injectors infected with HIV and 8 million living with chronic hepatitis C virus (HCV) infection. Estimates of program coverage are widely used in the c...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2011.09.030

    authors: Iversen J,Topp L,Wand H,Maher L

    更新日期:2012-05-01 00:00:00

  • The relationships of HIV status and HIV risky behavior with readiness for treatment.

    abstract::We investigated the associations of self-reported HIV status and risky injection practices with dependent variables measuring readiness and motivation for treatment and depression among 550 clients at two residential drug abuse treatment programs. The results suggest that a positive HIV status may be associated with m...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(94)90133-3

    authors: McCusker J,Bigelow C,Frost R,Hindin R,Vickers-Lahti M,Zorn M

    更新日期:1994-01-01 00:00:00

  • Area-level disadvantage and alcohol use disorder in northern Mexico.

    abstract:BACKGROUND:In Mexico, the Northern States are highly impacted by alcohol consumption and associated problems. Little is known about the association between contextual social disadvantage and alcohol use disorder in this region. METHODS:Information from 1265 current drinkers surveyed in the U.S.-Mexico Study on Alcohol...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2017.02.011

    authors: Orozco R,Benjet C,Ruiz Velasco-Acosta S,Moreno Altamirano L,Karriker-Jaffe KJ,Zemore S,Cherpitel C,Borges G

    更新日期:2017-06-01 00:00:00

  • Prevalence of depressive symptoms and associated factors among people who inject drugs in China.

    abstract:BACKGROUND:People who inject drugs (PWID) have a high prevalence of mental health problems (e.g., depression) which compromise the effects of HIV prevention. We investigated the prevalence of depression and associated factors among PWID in Dazhou, China. METHODS:Anonymous face-to-face interviews were administered to e...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2015.03.028

    authors: Li J,Gu J,Lau JT,Chen H,Mo PK,Tang M

    更新日期:2015-06-01 00:00:00

  • The pharmacokinetics of methamphetamine self-administration in male and female rats.

    abstract:BACKGROUND:Because methamphetamine (METH) pharmacokinetics after single iv doses show significant differences between male and female rats, we hypothesized that pharmacokinetic differences in METH disposition could be a contributing factor to the patterns of METH self-administration behaviors in rats. METHODS:For the ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2015.02.032

    authors: Milesi-Hallé A,Hambuchen MD,McMillan DE,Michael Owens S

    更新日期:2015-05-01 00:00:00

  • Gender-based differences in injecting drug use by young adults who experienced maltreatment in childhood: Findings from an Australian birth cohort study.

    abstract:BACKGROUND:Childhood maltreatment has been associated with a range of adverse mental and psychosocial outcomes, but its association with subsequent injecting drug use (IDU) is less clear. This study investigates the associations between specific and multiple forms of substantiated childhood maltreatment and IDU reporte...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2016.12.027

    authors: Abajobir AA,Kisely S,Williams G,Clavarino A,Strathearn L,Najman JM

    更新日期:2017-04-01 00:00:00

  • Cytotoxic effect of alcohol-withdrawal on primary cultures of cortical neurones.

    abstract::Physical dependence on alcohol was observed previously at the cellular level in cultured IM-9 human lymphoblast cells. To answer the question whether physical dependence can also develop in neurones and to investigate the neuronal processes involved in the development of alcohol dependence and withdrawal symptoms, cul...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/s0376-8716(00)00132-0

    authors: Nagy J,Müller F,László L

    更新日期:2001-01-01 00:00:00

  • Exposure opportunity as a mechanism linking youth marijuana use to hallucinogen use.

    abstract::The aim of this study is to shed light upon an observed association between the use of marijuana and hallucinogens (e.g. LSD), with a specific focus on the idea that two separate mechanisms might link marijuana use to hallucinogen use: (1) greater hallucinogen exposure opportunity for marijuana users versus nonusers; ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/s0376-8716(01)00191-0

    authors: Wilcox HC,Wagner FA,Anthony JC

    更新日期:2002-04-01 00:00:00

  • Problem drinking is associated with increased prevalence of sexual risk behaviors among men who have sex with men (MSM) in Lima, Peru.

    abstract:BACKGROUND:Alcohol use is an important but understudied HIV risk factor among men who have sex with men (MSM), particularly in Latin America. We studied the relationship between problem drinking and sexual risk among MSM in Lima, Peru. METHODS:We recruited 718 participants from 24 neighborhoods for a study on sexually...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2013.01.011

    authors: Deiss RG,Clark JL,Konda KA,Leon SR,Klausner JD,Caceres CF,Coates TJ

    更新日期:2013-09-01 00:00:00

  • Drinking and driving among American youth: beliefs and behaviors.

    abstract::Data from research on traffic accident populations clearly indicate that a large proportion of accidents involve drivers under the age of twenty-five. Even after differential exposure to traffic accidents has been controlled for, young drivers remain over-represented in both alcohol-related and non-alcohol-related tra...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/0376-8716(82)90084-9

    authors: Cameron TL

    更新日期:1982-09-01 00:00:00

  • DRD2 and DRD4 in relation to regular alcohol and cannabis use among adolescents: does parenting modify the impact of genetic vulnerability? The TRAILS study.

    abstract:AIMS:The aims of the present study were to determine the direct effect of DRD2 and DRD4, as well as their interaction with parenting (i.e. rejection, overprotection and emotional warmth), on the development of regular alcohol and cannabis use in 1192 Dutch adolescents from the general population. METHODS:Information w...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2010.10.008

    authors: Creemers HE,Harakeh Z,Dick DM,Meyers J,Vollebergh WA,Ormel J,Verhulst FC,Huizink AC

    更新日期:2011-05-01 00:00:00

  • Prescriber responses to a pain clinic law: Cease or modify?

    abstract:BACKGROUND:Pain clinic laws are designed to cease or modify high-risk prescribing behavior. However, prior evaluations have not differentiated between these types of prescriber responses in their analysis, even though they may have different implications for patients. The purpose of this analysis is to investigate the ...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2019.107591

    authors: Yenerall J,Buntin MB

    更新日期:2020-01-01 00:00:00

  • A vaccine against methamphetamine attenuates its behavioral effects in mice.

    abstract:BACKGROUND:Vaccines have treatment potential for methamphetamine (MA) addiction. We tested whether a conjugate vaccine against MA (succinyl-methamphetamine-keyhole limpet hemocyanin carrier protein; SMA-KLH) would generate MA antibodies and alter MA-induced behaviors. METHODS:Mice were injected with SMA-KLH and receiv...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2012.09.007

    authors: Shen XY,Kosten TA,Lopez AY,Kinsey BM,Kosten TR,Orson FM

    更新日期:2013-04-01 00:00:00

  • Craving predicts time to cocaine relapse: further validation of the Now and Brief versions of the cocaine craving questionnaire.

    abstract:BACKGROUND:The 10-item version of the cocaine craving questionnaire (CCQ-Brief) has not been validated in a mixed-gender sample, and predictive validity of the CCQ-Now and CCQ-Brief in terms of their relationship with cocaine relapse has not been demonstrated. OBJECTIVE:To further validate the CCQ-Brief in a mixed gen...

    journal_title:Drug and alcohol dependence

    pub_type: 杂志文章

    doi:10.1016/j.drugalcdep.2007.10.002

    authors: Paliwal P,Hyman SM,Sinha R

    更新日期:2008-03-01 00:00:00