Abstract：
:Alternaria species produce and excrete dimethyl coprogen siderophores to acquire iron. The Alternaria alternata gene AaNPS6, encoding a polypeptide analogous to fungal nonribosomal peptide synthetases, was found to be required for the production of siderophores and virulence on citrus. Siderophores purified from culture filtrates of the wild-type strain did not induce any phytotoxicity on the leaves of citrus. Fungal strains lacking AaNPS6 produced little or no detectable extracellular siderophores and displayed an increased sensitivity to H₂O₂, superoxide-generating compounds (KO₂ and menadione) and iron depletion. Δnps6 mutants were also defective for the production of melanin and conidia. The introduction of a wild-type AaNPS6 under the control of its endogenous promoter to a Δnps6 null mutant at least partially restored siderophore production and virulence to citrus, demonstrating a functional link between iron uptake and fungal pathogenesis. Elevated sensitivity to H₂O₂, seen for the Δnps6 null strain could be relieved by exogenous application of ferric iron. The expression of the AaNPS6 gene was highly up-regulated under low-iron conditions and apparently controlled by the redox-responsive yeast transcriptional regulator YAP1. Hence, the maintenance of iron homeostasis via siderophore-mediated iron uptake also plays an important role in resistance to toxic reactive oxygen species (ROS). Our results demonstrate further the critical role of ROS detoxification for the pathogenicity of A. alternata in citrus.
journal_name
Mol Plant Patholjournal_title
Molecular plant pathologyauthors
Chen LH,Lin CH,Chung KRdoi
10.1111/mpp.12021subject
Has Abstractpub_date
2013-06-01 00:00:00pages
497-505issue
5eissn
1464-6722issn
1364-3703journal_volume
14pub_type
杂志文章abstract：:Erwinia amylovora is the causal agent of fire blight, one of the most devastating diseases of apple and pear. Erwinia amylovora is thought to have originated in North America and has now spread to at least 50 countries worldwide. An understanding of the diversity of the pathogen population and the transmission to diff...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12647
更新日期：2018-07-01 00:00:00
abstract：:Plant viruses often harm their hosts, which have developed mechanisms to prevent or minimize the effects of virus infection. Resistance and tolerance are the two main plant defences to pathogens. Although resistance to plant viruses has been studied extensively, tolerance has received much less attention. Theory predi...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12629
更新日期：2018-06-01 00:00:00
abstract：:Natural and synthetic elicitors have contributed significantly to the study of plant immunity. Pathogen-derived proteins and carbohydrates that bind to immune receptors, allow the fine dissection of certain defence pathways. Lipids of a different nature that act as defence elicitors, have also been studied, but their ...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12252
更新日期：2015-12-01 00:00:00
abstract：:Crop diseases cause significant yield losses, and the use of resistant cultivars can effectively mitigate these losses and control many plant diseases. Most plant resistance (R) genes encode immune receptors composed of nucleotide-binding and leucine-rich repeat (NLR) domains. These proteins mediate the specific recog...
journal_title：Molecular plant pathology
pub_type： 杂志文章,评审
doi：10.1111/mpp.12723
更新日期：2018-11-01 00:00:00
abstract：UNLABELLED:summary Mycosphaerella graminicola is an important pathogen of wheat, causing septoria leaf blotch disease. This review summarizes the current knowledge on disease development and control of the fungus, and discusses how molecular tools and genomics are being employed to uncover the genetic basis of pathogen...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1046/j.1464-6722.2002.00100.x
更新日期：2002-03-01 00:00:00
abstract：:SUMMARY A new BglII satellite DNA has been isolated, cloned and sequenced from the coffee root-knot nematode, Meloidogyne exigua (Nematoda: Tylenchida). It is represented as tandemly repeated sequences with a monomeric unit of 277 bp. The monomers are present at approximately 17 900 copies per haploid genome, and repr...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1046/j.1364-3703.2002.00134.x
更新日期：2002-11-01 00:00:00
abstract：:Phytophthora sojae is a destructive pathogen of soybean [Glycine max (L.) Merr.] which causes stem and root rot on soybean plants worldwide. However, the pathogenesis and molecular mechanism of plant defence responses against P. sojae are largely unclear. Herein, we document the underlying mechanisms and function of a...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12741
更新日期：2019-01-01 00:00:00
abstract：:Xanthomonas albilineans, the causal agent of sugarcane leaf scald, is a bacterial plant pathogen that is mainly spread by infected cuttings and contaminated harvesting tools. However, some strains of this pathogen are known to be spread by aerial means and are able to colonize the phyllosphere of sugarcane before ente...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12276
更新日期：2016-02-01 00:00:00
abstract：:Sweet potato chlorotic stunt virus (SPCSV; genus Crinivirus, family Closteroviridae) is one of the most important pathogens of sweet potato (Ipomoea batatas L.). It can reduce yields by 50% by itself and cause various synergistic disease complexes when co-infecting with other viruses, including sweet potato feathery m...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2008.00480.x
更新日期：2008-09-01 00:00:00
abstract：:Nicotiana benthamiana is an important model plant for plant-microbe interaction studies. Here, we compared ribosome profiles and riboproteomes of healthy and infected N. benthamiana plants. We affinity purified ribosomes from transgenic leaves expressing a FLAG-tagged ribosomal large subunit protein RPL18B of Arabidop...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12764
更新日期：2019-03-01 00:00:00
abstract：:Abstract In prokaryotes, a diverse set of physiological processes is regulated by transcription factors which belong to the well-conserved, enhancer-binding protein (EBP) family. These regulatory proteins function together with the alternate sigma factor (sigma(54)). Structurally, the EBPs are characterized by a centr...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1046/j.1364-3703.2000.00028.x
更新日期：2000-07-01 00:00:00
abstract：:SUMMARY Pathogenic fungi have successfully attacked a wide range of hosts, which has forced them into ambient-adaptation. pH is one of the major ambient traits affecting the activity of pathogenicity factors secreted by the pathogen, hence, a pH sensing-response system was developed to enable the pathogen to tailor it...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1046/j.1364-3703.2003.00196.x
更新日期：2003-11-01 00:00:00
abstract：:Genetic and genomics tools to characterize host-pathogen interactions are disproportionately directed to the host because of the focus on resistance. However, understanding the genetics of pathogen virulence is equally important and has been limited by the high cost of de novo genotyping of species with limited marker...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12214
更新日期：2015-08-01 00:00:00
abstract：:Bacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is not only a disease devastating rice production worldwide, but also an ideal model system for the study of the interaction between plants and their bacterial pathogens. The rice near-isogenic line (NIL) CBB23, derived from a cross between a wild r...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12092
更新日期：2014-05-01 00:00:00
abstract：:The life cycle of the plant pathogen Erwinia amylovora comprises periods inside and outside the host in which it faces oxidative stress caused by hydrogen peroxide (H2 O2 ) and other compounds. The sources of this stress are plant defences, other microorganisms and/or exposure to starvation or other environmental chal...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12577
更新日期：2018-04-01 00:00:00
abstract：:In order to facilitate infection, the rice blast pathogen Magnaporthe oryzae secretes an abundance of proteins, including avirulence effectors, to diminish its host's defences. Avirulence effectors are recognized by host resistance proteins and trigger the host's hypersensitive response, which is a rapid and effective...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12468
更新日期：2017-10-01 00:00:00
abstract：:RNA interference (RNAi), a conserved RNA-mediated gene regulatory mechanism in eukaryotes, plays an important role in plant growth and development, and as an antiviral defence system in plants. As a counter-strategy, plant viruses encode RNAi suppressors to suppress the RNAi pathways and consequently down-regulate pla...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12229
更新日期：2015-09-01 00:00:00
abstract：:Fusarium oxysporum f. sp. radicis-cucumerinum (Forc) causes severe root rot and wilt in several cucurbit species, including cucumber, melon, and watermelon. Previously, a pathogenicity chromosome, chrRC , was identified in Forc. Strains that were previously nonpathogenic could infect multiple cucurbit species after ob...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12927
更新日期：2020-06-01 00:00:00
abstract：:SUMMARY We sought to identify Fusarium oxysporum f. sp. vasinfectum (Fov) genes that may be associated with pathogenicity. Initially we utilized microarray and Q-PCR technology to identify Fov genes expressed in root and hypocotyl tissues during a compatible infection of cotton. We identified 218 fungal clones represe...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2006.00327.x
更新日期：2006-03-01 00:00:00
abstract：:Amongst the universal diseases affecting apples, blue mould caused by Penicillium expansum is a major concern, resulting in yield and quality losses as a result of the production of the mycotoxin patulin. Despite the characterization of the patulin biosynthetic gene cluster at both the molecular and chemical levels, t...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12734
更新日期：2018-12-01 00:00:00
abstract：:The effector gene Avr1b-1 of Phytophthora sojae determines the efficacy of the resistance gene Rps1b in soybean. The sequences of the Avr1b-1 locus in 34 Chinese isolates of P. sojae were obtained and analysed by polymerase chain reaction (PCR) and inverse PCR. Four different alleles and a complete deletion mutation o...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2011.00733.x
更新日期：2012-02-01 00:00:00
abstract：:RXLR effectors encoded by Phytophthora species play a central role in pathogen-plant interactions. An understanding of the biological functions of RXLR effectors is conducive to the illumination of the pathogenic mechanisms and the development of disease control strategies. However, the virulence function of Phytophth...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12760
更新日期：2019-03-01 00:00:00
abstract：:The fungal cereal pathogen Fusarium graminearum produces deoxynivalenol (DON) during infection. The mycotoxin DON is associated with Fusarium head blight (FHB), a disease that can cause vast grain losses. Whilst investigating the suitability of Brachypodium distachyon as a model for spreading resistance to F. graminea...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12203
更新日期：2015-06-01 00:00:00
abstract：:Efficient and sustainable control of plant viruses may be achieved using genetically resistant crop varieties, although resistance genes are not always available for each pathogen; in this regard, the identification of new genes that are able to confer broad-spectrum and durable resistance is highly desirable. Recentl...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2012.00785.x
更新日期：2012-09-01 00:00:00
abstract：:Knowledge of the structure of a viroid is critically important to elucidate the roles played by the various RNA motifs in the steps of the viroid's life cycle. A new technique, RNA-selective 2'-hydroxyl acylation analysed by primer extension (SHAPE), has recently been shown to be fast, reliable and applicable to the s...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2010.00703.x
更新日期：2011-09-01 00:00:00
abstract：:The vascular pathogen Xanthomonas oryzae pv. oryzae (Xoo) and nonvascular pathogen Xanthomonas oryzae pv. oryzicola (Xoc) cause bacterial blight (BB) and bacterial leaf streak (BLS) diseases of rice, respectively. We have previously identified the avirulence gene avrXa27 from Xoo PXO99(A), which specifically induces t...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2008.00509.x
更新日期：2009-01-01 00:00:00
abstract：:MicroRNAs (miRNAs) play essential roles in plant development. There is increasing evidence that changed expression of miRNAs in virus-infected plants contributes to the development of viral symptoms. Here, we analysed the altered expression of miRNAs of Nicotiana benthamiana in response to Potato virus X (PVX) by Illu...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12717
更新日期：2018-11-01 00:00:00
abstract：:SUMMARY The phytotoxin coronatine (COR) contributes to the virulence of Pseudomonas syringae pv. tomato (Pst) strain DC3000 on Arabidopsis thaliana and tomato. However, little is known regarding the role of COR in the virulence of DC3000 on cultivated Brassica spp. In this study, the role of COR and its precursors, co...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/j.1364-3703.2006.00372.x
更新日期：2007-01-01 00:00:00
abstract：:Meloidogyne enterolobii is one of the most important plant-parasitic nematodes that can overcome the Mi-1 resistance gene and damage many economically important crops. Translationally controlled tumour protein (TCTP) is a multifunctional protein that exists in various eukaryotes and plays an important role in parasiti...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12374
更新日期：2017-01-01 00:00:00
abstract：:Black spot disease, which is caused by the ascomycete Diplocarpon rosae, is the most severe disease in field-grown roses in temperate regions and has been distributed worldwide, probably together with commercial cultivars. Here, we present data indicating that muRdr1A is the active Rdr1 gene, a single-dominant TIR-NBS...
journal_title：Molecular plant pathology
pub_type： 杂志文章
doi：10.1111/mpp.12589
更新日期：2018-05-01 00:00:00
