Abstract:
:Because of ever-increasing throughput requirements of sequencing data, most existing short-read aligners have been designed to focus on speed at the expense of accuracy. The Genome Multitool (GEM) mapper can leverage string matching by filtration to search the alignment space more efficiently, simultaneously delivering precision (performing fully tunable exhaustive searches that return all existing matches, including gapped ones) and speed (being several times faster than comparable state-of-the-art tools).
journal_name
Nat Methodsjournal_title
Nature methodsauthors
Marco-Sola S,Sammeth M,Guigó R,Ribeca Pdoi
10.1038/nmeth.2221subject
Has Abstractpub_date
2012-12-01 00:00:00pages
1185-8issue
12eissn
1548-7091issn
1548-7105pii
nmeth.2221journal_volume
9pub_type
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