The GEM mapper: fast, accurate and versatile alignment by filtration.

Abstract:

:Because of ever-increasing throughput requirements of sequencing data, most existing short-read aligners have been designed to focus on speed at the expense of accuracy. The Genome Multitool (GEM) mapper can leverage string matching by filtration to search the alignment space more efficiently, simultaneously delivering precision (performing fully tunable exhaustive searches that return all existing matches, including gapped ones) and speed (being several times faster than comparable state-of-the-art tools).

journal_name

Nat Methods

journal_title

Nature methods

authors

Marco-Sola S,Sammeth M,Guigó R,Ribeca P

doi

10.1038/nmeth.2221

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

1185-8

issue

12

eissn

1548-7091

issn

1548-7105

pii

nmeth.2221

journal_volume

9

pub_type

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