Effect of an Ilex asprella root decoction on the related genes of lipid metabolism from chronic stress and hyperlipidemic fatty liver in rats.

abstract：OBJECTIVE:To assess whether Angiotensin II (Ang II) and carbon tetrachloride (CCl(4)) used in combination could accelerate the process of fibrosis and whether Ang II play a role in exagerating hepatic fibrosis in rats. METHODS:Ang II was injected into the abdominal cavity of Sprague-Dawley (SD) rats together with subc...

journal_title：Chinese medical journal

authors： Zhou X,Li D,Li X,Lu H,Zhang W

更新日期：2003-01-01 00:00:00

abstract：:The phenotypes of mononuclear cells in 16 patients with mycosis fungoides (MF) (8 were in tumor stage and 8 in pretumor stage) were tested by ABC immunochemical technique. The results showed that the percentage of CD38 and Leu6(+) cells in tumor stage was higher than that in pretumor stage. CD38 was identified to be a...

journal_title：Chinese medical journal

authors： Liu JH,Zhang Q,Shi YF,Zeng XS,Wang XH,Li J,Chen Z,Shen DC

更新日期：1993-05-01 00:00:00

abstract：:Cogan’s syndrome (CS) is a rare inflammatory disorder characterized by interstitial keratitis and vestibuloauditory abnormalities often associated with various systemic manifestations. Involvement of cardiovascular system resembling systemic vasculitis may lead to severe complications and death. The present report des...

journal_title：Chinese medical journal

authors： Branislava I,Marijana T,Nemanja D,Dragan S,Maja Z

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To have a better understanding of genetic contributions to the development of obstructive sleep apnea hypopnea syndrome (OSAHS) by reviewing studies on its genetic basis. DATA SOURCES:A comprehensive search of the PubMed literature without restriction on the publication date was carried out using terms "obst...

journal_title：Chinese medical journal

authors： Zhang D,Xiao Y,Luo J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The medium-to-long-term use of antimuscarinics alone or in combination with an α-blocker in men with an enlarged prostate is still controversial. This double-blind, placebo-controlled, randomized clinical trial aimed to investigate the efficacy and safety of medium-to-long-term use of tolterodine extended re...

journal_title：Chinese medical journal

authors： Cai JL,Zhou Z,Yang Y,Yan YF,Jing S,Na YQ

更新日期：2016-12-20 00:00:00

abstract：BACKGROUND:With the development of magnetic resonance (MR) technologies, whole-body 3D contrast-enhanced MR angiography (3D CE MRA) has become possible. The purpose of this study was to introduce and evaluate this technique in demonstration of various systemic arterial diseases. METHODS:Thirty-seven patients underwent...

journal_title：Chinese medical journal

authors： Lin J,Chen B,Wang JH

更新日期：2006-11-05 00:00:00

abstract：:Enhanced recovery after cesarean (ERAC) delivery is an evidence-based, multi-disciplinary approach throughout pre-, intra-, post-operative period. The ultimate goal of ERAC is to enhance recovery and improve the maternal and neonatal outcomes. This review highlights the role of anesthesiologist in ERAC protocols. This...

journal_title：Chinese medical journal

authors： Liu ZQ,Du WJ,Yao SL

更新日期：2020-03-05 00:00:00

abstract：OBJECTIVE:To assess the therapeutic effects of long-term albendazole therapy in intraabdominal cystic echinococcosis. METHODS:Fifteen patients with a total of 45 cysts were treated with albendazole with dosage regimen of 20 mg.kg-1.d-1 for an average of 2.5 years. Repeated CT and ultrasound scannings (US) were perform...

journal_title：Chinese medical journal

authors： Liu Y,Wang X,Wu J

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To evaluate whether hypermethylation of calcitonin (CT) gene could serve as a transforming signal of myelodysplastic syndrome (MDS) to leukemia. METHODS:Bone marrow aspirates from 35 MDS patients, including 25 refractory anemia (RA), 10 refractory anemia with excess of blasts (RAEB) or refractory anemia with...

journal_title：Chinese medical journal

authors： Wu S,Xie G,Bai R,Wang Y,Zhu P

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer is a highly malignant tumor affecting an ever increasing number of patients with a mean 5-year survival rate below 4%. Therefore, gene therapy for cancer has become a potential novel therapeutic modality. In this study we sought to determine the inhibitory effects of adenovirus-mediated hum...

journal_title：Chinese medical journal

authors： Pan XT,Zhu QY,Li DC,Yang JC,Zhang ZX,Zhu XG,Zhao H

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Extracellular matrix (ECM) orchestrates cell behaviour including growth, death, apoptosis, adhesion, migration, and invasion by activating several signalling pathways. Certain components of ECM, such as integrins, may act as receptors or co-receptors of enterovirus. ECM-activated gene expressions in myocardi...

journal_title：Chinese medical journal

authors： Zhang ZC,Li SJ,Yang YZ,Chen RZ,Ge JB,Chen HZ

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

journal_title：Chinese medical journal

authors： Zhou Z,Li L,Yu Y,Ma Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Ischemic disease is one of the leading causes of death in the world. In order to further study gene therapy for ischemic disease, we constructed a recombinant plasmid for co-expression of human angiopoietin-1 and vascular endothelial growth factor 165(VEGF165) gene in adeno-associated virus (AAV) gene delive...

journal_title：Chinese medical journal

authors： Chen DJ,Tan Z,Xie YL,Liu F

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to prospectively study the changes in neutrophil elastase (NE), fibroblast growth factor 9 (Fgf9), matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase 1 (TIMP-1) in sputum induced during the early period after lung volume reduction surgery (LVRS). METHODS:From...

journal_title：Chinese medical journal

authors： Miao JB,Hou SC,Li H,Hu B,Wang TY

更新日期：2008-09-20 00:00:00

abstract：OBJECTIVE:To study the interaction between oncogene mdm2 and wp53 in human glandular lung cancer cell line GLC-82. METHODS:By lipofectamine-mediated DNA transfection, wp53 and mdm2 were transfected separately or co-transfected into GLC-82 cells via retrovival vector pDOR-neo, a carrier of wp53 and mdm2. RESULTS:The g...

journal_title：Chinese medical journal

authors： Li P,Rao G,Chen Y,Ding Z,Yu W

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Urine output (UO) is an essential criterion of the Kidney Disease Improving Global Outcomes (KDIGO) definition and classification system for acute kidney injury (AKI), of which the diagnostic value has not been extensively studied. We aimed to determine whether AKI based on KDIGO UO criteria (KDIGOUO) could ...

journal_title：Chinese medical journal

authors： Qin JP,Yu XY,Qian CY,Li SS,Qin TH,Chen EZ,Lin JD,Ai YH,Wu DW,Liu DX,Sun RH,Hu ZJ,Cao XY,Zhou FC,He ZY,Zhou LH,An YZ,Kang Y,Ma XC,Zhao MY,Jiang L,Xu Y,Du B,China Critical Care Clinical Trial Group (CCCCTG).

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel re...

journal_title：Chinese medical journal

authors： Tang XF,Zhang JH,Wang J,Han YL,Xu B,Qiao SB,Wu YJ,Chen J,Wu Y,Chen JL,Gao RL,Yang YJ,Yuan JQ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Cigarette smoke induces an acute but persisting inflammation in peripheral blood and airway in chronic obstructive pulmonary disease (COPD), and CD8(+) Tc-lymphocytes are considered as a key role in this process. We aimed to investigate the Tc-lymphocytes immunodeviation in system and local airway of COPD pa...

journal_title：Chinese medical journal

authors： Yu MQ,Liu XS,Wang JM,Xu YJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The long-term safety and efficacy of drug-eluting stents (DES) versus bare metal stents (BMS) are unclear and controversial issues in patients with acute ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The purpose of this study was to compare the long-t...

journal_title：Chinese medical journal

authors： Wang CH,Fang Q,Zhang SY,Shen ZJ,Fan ZJ,Jin XF,Zeng Y,Liu ZY,Xie HZ,Yang M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Hypoxic pulmonary hypertension (HPH) is initiated by inhibition of O2-sensitive, voltage-gated (Kv) channels in pulmonary arterial smooth muscle cells (PASMCs). The mechanism of hypoxic pulmonary hypertension has not yet been fully elucidated. The mitochondrial ATP-sensitive K+ channel (MitoKATP) is extremel...

journal_title：Chinese medical journal

authors： Wang T,Zhang ZX,Xu YJ

更新日期：2005-01-05 00:00:00

abstract：BACKGROUND:Serum antinuclear antibodies (ANAs) are positive in some patients with chronic lymphocytic leukemia (CLL), but the prognostic value of ANAs remains unknown. The aim of this study was to evaluate the role of ANAs as a prognostic factor in CLL. METHODS:This study retrospectively analyzed clinical data from 21...

journal_title：Chinese medical journal

authors： Sun Q,Wang L,Zhu HY,Miao Y,Wu W,Liang JH,Cao L,Xia Y,Wu JZ,Wang Y,Wang R,Fan L,Xu W,Li JY

更新日期：2019-03-05 00:00:00

abstract：OBJECTIVE:To study if the functions of C gene and its promotor are related to the pathogenesis of hepatitis B and to describe their hot spot mutations in Chinese patients. DATA SOURCES:We have studied this subject in recent years. A mini-review is based on some unpublished works. DATA SELECTION:The sequence data of C...

journal_title：Chinese medical journal

authors： Luo K

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drug-resistant epilepsy. Acupuncture is also used to treat epilepsy. This study was designed to examine the safety and effectiveness of transcutaneous auricular vagus nerve stimulation (ta-VNS) for patients with drug...

journal_title：Chinese medical journal

authors： Rong P,Liu A,Zhang J,Wang Y,Yang A,Li L,Ben H,Li L,Liu R,He W,Liu H,Huang F,Li X,Wu P,Zhu B

更新日期：2014-01-01 00:00:00

abstract：:In present study, we examined the effects of NG-nitro-L-arginine (LNNA), an inhibitor of nitric oxide synthase (NOS), and/or methylene blue (MB), a blocker of guanylate cyclase on the vasodilator response of isolated rat arteries including aorta and mesenteric artery to calcitonin gene-related peptide (CGRP) by in vit...

journal_title：Chinese medical journal

authors： Tan DY,Zhang LZ,Zhao YT,Zhao D,Tang J

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To characterize the mRNA expression of CXC chemokine IL-8, CC chemokine monocyte chemothractant protein-1 (MCP-1) and regulated on activation, normal T cell expressed and secreted (RANTES), and a newly defined DC chemokine DC-CK1 as well as the expression of IL-8 receptor, MCP-1 receptor and RANTES receptor i...

journal_title：Chinese medical journal

authors： Zhu K,Shen Q,Ulrich M,Zheng M

更新日期：2000-12-01 00:00:00

abstract：:Type 2 diabetes mellitus and metabolic disorders have become an epidemic globally. However, the pathogenesis remains largely unclear and the prevention and treatment are still limited. In addition to environmental factors during adulthood, early life is the critical developmental window with high tissue plasticity, wh...

journal_title：Chinese medical journal

authors： Zhou LY,Deng MQ,Zhang Q,Xiao XH

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Multiple neonatal characteristics and adult cardiovascular risk factors are associated with the development of atherosclerosis, however little conclusive evidence exists characterizing the relative strength of these factors. In a large retrospective study, we investigated the association between both objecti...

journal_title：Chinese medical journal

authors： Lin X,Zhu WL,Tan L,Xu T,Xu RY,Fang Q,Zhang SY,Zhang ZX

更新日期：2010-09-01 00:00:00

abstract：Background:Technical aspects of the correct placement of medial support locking screws in the locking plate for proximal humerus fractures remain incompletely understood. This study was to evaluate the clinical relationship between the number of medial support screws and the maintenance of fracture reduction after lock...

journal_title：Chinese medical journal

authors： Zeng LQ,Zeng LL,Jiang YW,Wei HF,Zhang W,Chen YF

更新日期：2018-08-05 00:00:00

abstract：OBJECTIVE:To analysis the pathological demography in Chinese patients undergoing renal biopsy from our nephrology center. METHODS:Between January 1979 and October 2000 in Jinling Hospital, Nanjing, China, 10,002 attempts of percutaneous renal were performed in patients with renal disease from 33 provinces of China. Th...

journal_title：Chinese medical journal

authors： Chen H,Tang Z,Zeng C,Hu W,Wang Q,Yu Y,Yao X,Wang J,Zhu M,Zhou H,Liu H,Liu Z,Li L

更新日期：2003-09-01 00:00:00

abstract：:Twin pregnancy with mosaic partial hydatidiform mole (PHM) and survival of two healthy fetuses following in vitro fertilization and embryos transfer (IVF-ET) is a rare situation and is considered a challenge for management. A 32-year-old Chinese woman conceived twin pregnancy following IVF-ET. At 22 weeks' gestation, ...

journal_title：Chinese medical journal

authors： Sun CJ,Zhao YP,Yu S,Fan L,Wu QQ,Li GH,Zhang WY

更新日期：2012-12-01 00:00:00