Abstract：
INTRODUCTION:Iron overload is a major problem in patients with b-thalassemia major, and it has many structural and metabolic consequences. In this study, we aimed to consider the prevalence of endocrine abnormalities in patients with β-thalassemia major and thalassemia intermedia. MATERIALS AND METHODS:We ordered following tests for consideration endocrine abnormalities: fasting plasma glucose, oral glucose tolerance, iron, total iron binding capacity, ferritin, thyroid-stimulating hormone (TSH), free thyroxin (fT4), free triiodothyronine (fT3), parathyroid hormone levels. RESULTS:According to our study including 70 patients with thalassemia major, 7 (10%) had diabetes, 5 (7.1%) had impaired glucose tolerance, 9 (12.8%) had hypothyroidism, 2 (2.8%) had hypoparathyroidism, 2 (2.8%) had hyperparathyroidism. Of 22 patients with thalassemia intermedia, 1 (4.5%) had diabetes. CONCLUSIONS:These findings reinforce the importance of regular follow-up of patients with b-thalassemia major and thalassemia intermedia for early detection and management of associated complications. In this way, the prevalence of endocrine abnormalities can be decreased in future.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Kurtoglu AU,Kurtoglu E,Temizkan AKsubject
Has Abstractpub_date
2012-01-01 00:00:00pages
260-3issue
4eissn
0423-104Xissn
2299-8306journal_volume
63pub_type
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
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journal_title：Endokrynologia Polska
pub_type： 杂志文章,评审
doi：
更新日期：2009-09-01 00:00:00
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更新日期：2010-07-01 00:00:00
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journal_title：Endokrynologia Polska
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pub_type： 杂志文章
doi：
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journal_title：Endokrynologia Polska
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
doi：
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pub_type： 杂志文章
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journal_title：Endokrynologia Polska
pub_type： 杂志文章
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journal_title：Endokrynologia Polska
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