Abstract：
:Pontine parabrachial neurons have been suggested to play a regulatory role in both respiratory and sleep cycle control. Encouraged by the finding that microinjections of the cholinergic agonist carbachol into the medial pontine reticular formation (mPRF) of the cat produced respiratory changes paralleling those observed during rapid eye movement (REM) sleep (Neurosci. Lett., 102 (1989) 211-216), this study tested the hypothesis that cholinergic mechanisms in the mPRF can also cause state-dependent changes in the discharge of parabrachial neurons. This paper describes extracellular recordings of parabrachial neurons during REM sleep and during the carbachol-induced REM sleep-like state (DCarb). Cells which were activated (REM-on) or inactivated (REM-off) during REM maintained the same state-dependent firing patterns during the DCarb state. These results support the hypothesis that cholinergic mechanisms in the mPRF can cause state-dependent changes in the discharge of parabrachial neurons.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Gilbert KA,Lydic Rdoi
10.1016/0304-3940(90)90049-fsubject
Has Abstractpub_date
1990-12-11 00:00:00pages
241-4issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(90)90049-Fjournal_volume
120pub_type
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journal_title：Neuroscience letters
pub_type： 杂志文章,评审
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
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pub_type： 杂志文章
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更新日期：2009-11-06 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.10.109
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journal_title：Neuroscience letters
pub_type： 杂志文章
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journal_title：Neuroscience letters
pub_type： 杂志文章
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