Abstract:
PURPOSE:To reanalyze results reported in 2008, using propensity score matching, to test the treatment effect of non-leisure physical activity on survival. METHODS:McCullagh's ordinal logit model was used to estimate propensity scores, separately for adults aged 35-59 and 60-74 years at baseline in the National Health and Nutrition Examination Survey I Epidemiologic Followup Study, for three levels of non-leisure activity. Each untreated adult (low non-leisure activity) was matched to two treated adults from the same age group, one with moderate and one with high non-leisure activity. Multivariable Cox proportional hazard regressions were fitted to the matched samples and compared with regressions fitted to unmatched samples. RESULTS:Except for moderate leisure-time activity and age, observed covariates were well balanced after matching. For adults aged 35-59 years, matched regressions showed smaller mortality reductions: 23% for moderate and 32% for high non-leisure activity, compared with low non-leisure activity. For adults aged 60-74 years, matched regressions showed a smaller mortality reduction for moderate non-leisure activity (29%) but a larger reduction for high non-leisure activity (47%). CONCLUSIONS:In line with published reviews of conventional multivariable analysis versus propensity score matching, Cox regressions on matched and unmatched samples produced similar estimates of treatment effects for non-leisure activity, but the estimates from matched regressions were usually smaller.
journal_name
Ann Epidemioljournal_title
Annals of epidemiologyauthors
Park J,Russell LBdoi
10.1016/j.annepidem.2012.04.019subject
Has Abstractpub_date
2012-08-01 00:00:00pages
575-80issue
8eissn
1047-2797issn
1873-2585pii
S1047-2797(12)00113-5journal_volume
22pub_type
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