Abstract：
:Antioxidants play a vital role in protecting the skin from environmental distress. As the skin is constantly exposed to harmful UV radiation, endogenous antioxidants present in the superficial layers of the skin neutralize reactive oxygen species. Over time, antioxidants become depleted and loss their protective effect on the skin. Therefore, supplementing skin with topical antioxidant can help replenish this loss and fight the oxidative stress. The objective of this study was to deliver antioxidants topically and quantify the amount permeated in the stratum corneum and underlying skin. Polyphenols (catechin, resveratrol and curcumin) and vitamin (retinol) with various lipophilic properties were delivered via porcine ear skin, using propylene glycol as a vehicle. The amount in the stratum corneum and underlying skin was quantified using tape stripping and skin extraction methods, respectively, and samples were analysed via HPLC. All four antioxidants permeated into the skin from the propylene glycol vehicle. The order of the amount of antioxidant in the stratum corneum was catechin > resveratrol~ retinol> curcumin, whereas that in the underlying skin was retinol > catechin~ resveratrol~ curcumin. Of the total amount of polyphenols in the skin, approximately 90% was retained in the stratum corneum whereas 10% was quantified in the underlying skin. In contrast, 10% of retinol was retained in the stratum corneum whereas 90% permeated in the underlying skin. Polyphenols (catechin, resveratrol and curcumin) showed high concentration in the stratum corneum whereas retinol showed high accumulation in the underlying layers of the skin.
journal_name
Int J Cosmet Scijournal_title
International journal of cosmetic scienceauthors
Abla MJ,Banga AKdoi
10.1111/j.1468-2494.2012.00728.xsubject
Has Abstractpub_date
2013-02-01 00:00:00pages
19-26issue
1eissn
0142-5463issn
1468-2494journal_volume
35pub_type
杂志文章abstract：OBJECTIVE:Equol has been shown to improve skin health and regeneration, due to its antioxidative, phytoestrogenic and epigenetic characteristics. The effects of a topical intervention on skin structure, telomere length and epigenetic markers in skin cells were analysed. METHODS:Sixty-four participants were divided in ...
journal_title：International journal of cosmetic science
pub_type： 杂志文章,随机对照试验
doi：10.1111/ics.12408
更新日期：2017-10-01 00:00:00
abstract：:This study was a pilot project, set up to assess ageing skin using a multi-disciplinary approach. The main aim of this study was to evaluate whether the use of more radical ('medical') treatments in the management of skin ageing would bring superior results and ultimately make people look younger, than the use of cosm...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1468-2494.2012.00741.x
更新日期：2012-10-01 00:00:00
abstract：:Synopsis An investigation has been carried out into the synthesis of quaternary ammonium salts of triglycerides. The aim of this work was to produce such compounds without breaking the triglyceride skeleton. The reaction of chloracetyl chloride with the triglyceride of ricinoleic acid which is the major constituent (8...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1991.tb00560.x
更新日期：1991-08-01 00:00:00
abstract：:Synopsis The influence of the following hydrophilic polymers on the stability of emulsions has been studied: sodium carboxymethyl cellulose, hydroxyethyl cellulose, agar-agar, water dispersible clay, and a neutralized polyethylene acid. The oil phases used were paraffin oil, olive oil and a synthetic C(8)-C(12) trigly...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1984.tb00374.x
更新日期：1984-08-01 00:00:00
abstract：OBJECTIVE:The aim of this work was to investigate an alternative hair-dyeing method with vegetable colourants as the tannins, as well as the impact of pre-treatment as the bleaching process. METHODS:Untreated, 1, 2 and 3 times bleached hair tresses that were dyed with tannins in combination with metal salts were chara...
journal_title：International journal of cosmetic science
pub_type： 杂志文章,评审
doi：10.1111/ics.12624
更新日期：2020-08-01 00:00:00
abstract：:Synopsis The synthesis of 5-alkoxy and 5-aryloxymethylene-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ones by reaction of (+)-5-hydroxymethylene-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-one with a number of saturated or unsaturated alcohols and phenols in order to check how substituents affected the fragrance, is des...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1995.tb00108.x
更新日期：1995-04-01 00:00:00
abstract：:Lecithin has an antioxidative potential that depends directly on the content of phospholipids. Purified lecithin with a higher phospholipid content exerts better antioxidative properties. Furthermore, due to its specific physico-chemical properties, amphiphility in particular, the phospholipid the largest portion of t...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1046/j.1467-2494.1999.181682.x
更新日期：1999-08-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to develop formulations to deliver physiological lipids into skin in an attempt to repair defective barrier function. METHODS:Physiological cholesterol and linoleic acid were incorporated into basic cream and non-ionic cream to prepare skin repair formulations. Homogeneity and storag...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/ics.12491
更新日期：2018-10-01 00:00:00
abstract：:Synopsis In this study a compact, hand-held, solid state erythema meter using light emitting diodes is described. This device has been constructed and used to compare with visual assessments of ultraviolet radiation in human subjects. A statistically significant correlation was obtained between erythema index and visu...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1990.tb00521.x
更新日期：1990-04-01 00:00:00
abstract：:Microbiological quality control of personal care products using traditional methods can take between 5 and 7 days to complete. This is frequently the rate limiting step in product release. Companies are looking to improve manufacturing efficiencies and to maximize resources by releasing products faster. ATP biolumines...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1046/j.1467-2494.1998.171736.x
更新日期：1998-02-01 00:00:00
abstract：OBJECTIVE:A comprehensive methodology for the simultaneous determination of 15 multiclass organic UV filters in sunscreen cosmetics was developed using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). METHODS:Sunscreen cosmetics of various matrices,...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/ics.12387
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Bromelain is a mixture of proteolytic enzymes found in various tissues of the pineapple plant (Ananas comosus) and other species of Bromeliaceae. Owing to its proteolytic activity, bromelain has been used in the food, medical, pharmaceutical and cosmetic industries, for its cell renewal, anti-ageing, whiteni...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/ics.12308
更新日期：2016-10-01 00:00:00
abstract：:The stratum corneum is the outermost layer of the skin. It constitutes a permeability barrier that keeps micro-organisms and toxic agents from entering the skin, while retaining water and electrolytes. In order to preserve its colour and elasticity, the skin needs lipids and water. Certain occlusive products in contac...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.2007.00357.x
更新日期：2007-04-01 00:00:00
abstract：:Synopsis This report utilizes a new procedure based on epidermal stripping to analyse unlabelled skin fatty acids. This technique was applied to the study of human dry skin treated with blackcurrant seed oil, an essential fatty acid rich lipid also containing gamma linolenic acid. In human dry skin the usual fatty aci...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1988.tb00014.x
更新日期：1988-08-01 00:00:00
abstract：:Synopsis In the last few years a lot of attention has been paid to the development of the in vitro models which would substitute for animals in cutaneous irritancy studies. These models explore either organ or explant cultures using freshly excised skin or serial cultures of isolated skin cells (epidermal keratinocyte...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1992.tb00058.x
更新日期：1992-12-01 00:00:00
abstract：:Cutaneous irritation is a stereotyped response of the skin to any physical or chemical insult. Its main manifestations encompass inflammatory erythema and an alteration of the cutaneous microrelief showing increased roughness, dehydration and erratic desquamation. Several instrumental methods can indirectly assess the...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1046/j.1467-2494.2003.00170.x
更新日期：2003-04-01 00:00:00
abstract：:Summary The activity of thioglycolic acid, incorporated in a microemulsion, towards cystine residues present in keratin proteins has been investigated. In an attempt to relate the structural state of the microemulsions to cystine reactivity, an appropriate model system showing a large microemulsion domain with diverse...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1987.tb00476.x
更新日期：1987-10-01 00:00:00
abstract：:Cocamidopropyl betaine (CAPB) has been the most important secondary surfactant for personal-cleansing products for a long time. Its excellent toxicological profile is an important reason for its increasing use in oral-care products. Recently it has gained interest for further applications such as household cleaners, d...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1046/j.1467-2494.1997.171719.x
更新日期：1997-10-01 00:00:00
abstract：:Many cosmetics contain keratolytic hydroxy acids to correct the effects of photoageing on human skin. Although methods exist for quantifying the alpha-hydroxy acid, glycolic acid in aqueous media, accurate methods for quantification in mixed hydrophobic and aqueous cosmetic creams and lotions are lacking. Glycolic aci...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1046/j.1467-2494.2002.00128.x
更新日期：2002-04-01 00:00:00
abstract：OBJECTIVE:To study the effects of addition of a redox metal, copper, antioxidants and metal chelators on the formation of free radicals in natural white Caucasian hair subsequently exposed to UV light. Three different methods, electron paramagnetic resonance (EPR), a fluorescent probe for hydroxyl radical formation (te...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/ics.12601
更新日期：2020-04-01 00:00:00
abstract：:The causative substances for axillary osmidrosis, which are often found in apocrine sweat, are the decomposed/denatured products of short-chain fatty acid and other biological metabolite compounds produced by axillary-resident bacteria. Conventional underarm deodorants suppress the process of odour production mostly b...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.2006.00322.x
更新日期：2006-08-01 00:00:00
abstract：:Kajal and surma are eye cosmetics extensively used in Indian subcontinent. Kajal is prepared by burning of vegetable oil and butter oil while surma by grinding of the stones. High performance liquid chromatography and gas chromatography-mass spectrometry instruments were used for quantification and confirmation of 16 ...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1468-2494.2009.00497.x
更新日期：2009-06-01 00:00:00
abstract：:Synopsis The ability of baseline transepidermal water loss (TEWL) measurements to predict the response of healthy subjects to a standard soap chamber irritation insult was evaluated. Chambers containing surfactant solutions were applied to the forearms of normal volunteers for five consecutive days. TEWL was measured ...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1986.tb00452.x
更新日期：1986-10-01 00:00:00
abstract：OBJECTIVE:The present investigation is based on the formulation of water-in-oil (w/o) cream preparations of ascorbic acid (AA) at pH 4-6 using different emollients and humectants. METHODS:The preparations were stored in the dark at 30°C for a period of 3 months and were studied for their chemical and physical stabilit...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/ics.12152
更新日期：2014-10-01 00:00:00
abstract：:Variable skin pH values are being reported in literature, all in the acidic range but with a broad range from pH 4.0 to 7.0. In a multicentre study (N = 330), we have assessed the skin surface pH of the volar forearm before and after refraining from showering and cosmetic product application for 24 h. The average pH d...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.2006.00344.x
更新日期：2006-10-01 00:00:00
abstract：:In the present study, we tested a new device called skin phototype diagnosis (SPD) built for the purpose of objectively determining skin phototype. We compared its performance with that of phototype determinations according to Fitzpatrick method and on tristimulus colorimetry (Minolta CR-200). Our population consisted...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1046/j.1467-2494.2002.00136.x
更新日期：2002-08-01 00:00:00
abstract：:Synopsis The non-saponifiable lipidic fractions of avocado and soya bean applied percutaneously to hairless rats for 15 days had been shown to produce biochemical modifications of dermal connective tissue components: increases of soluble collagen and of the ratio soluble collagen/insoluble collagen. In this present st...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.1982.tb00310.x
更新日期：1982-08-01 00:00:00
abstract：:There is an increasing demand in general population regarding skin healthiness and improvement of aesthetical appearance, indicating that people require more information about how to treat healthy skin and to prevent skin disease. This study is the result of a campaign on healthy skin organized by the International So...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.2005.00287.x
更新日期：2005-12-01 00:00:00
abstract：:Cutaneous ageing is the result of two distinct, biological processes which may occur concurrently: (i) the passage of time, termed intrinsic ageing and (ii) environmental influences, termed extrinsic ageing. Intrinsic ageing of the skin is a slow process which causes changes in tissue structure and impairs function in...
journal_title：International journal of cosmetic science
pub_type： 杂志文章,评审
doi：10.1111/j.1468-2494.2010.00574.x
更新日期：2010-10-01 00:00:00
abstract：:In recent years the importance of sphingolipids (cerebrosides, sphingomyelin, ceramides, sphingosine-1-phospate, etc.) in skin biology is receiving an increasing interest. Not only are ceramides essential for the barrier function of the skin, especially through their phytosphingosine, sphingosine and 6-hydroxysphingos...
journal_title：International journal of cosmetic science
pub_type： 杂志文章
doi：10.1111/j.1467-2494.2007.00394.x
更新日期：2007-08-01 00:00:00
