Abstract:
:In 288 men and women from general population in a cross-sectional survey, all neuropsychological tests were negatively associated with age; memory and executive function were also positively related with education. The hypertensives (HT) were less efficient than the normotensives (NT) in the test of memory with interference at 10 sec (MI-10) (-33%, P = 0.03), clock drawing test (CLOX) (-28%, P < 0.01), and mini-mental state examination (MMSE) (-6%, P = 0.02). Lower MMSE, MI-10, and CLOX were predicted by higher systolic (odds ratio, OR, 0.97, P = 0.02; OR 0.98, P < 0.005; OR 0.95, P < 0.001) and higher pulse blood pressure (BP) (OR 0.97, P = 0.02; OR 0.97, P < 0.01; and 0.95, P < 0.0001). The cognitive reserve index (CRI) was 6% lower in the HT (P = 0.03) and was predicted by higher pulse BP (OR 0.82, P < 0.001). The BP vectors of lower MMSE, MI-10, and CLOX were directed towards higher values of systolic and diastolic BP, that of low CRI towards higher systolic and lower diastolic. The label of hypertension and higher values of systolic or pulse BP are associated to worse memory and executive functions. Higher diastolic BP, although insufficient to impair cognition, strengthens this association. CRI is predicted by higher systolic BP associated to lower diastolic BP.
journal_name
Int J Hypertensjournal_title
International journal of hypertensionauthors
Giordano N,Tikhonoff V,Palatini P,Bascelli A,Boschetti G,De Lazzari F,Grasselli C,Martini B,Caffi S,Piccoli A,Mazza A,Bisiacchi P,Casiglia Edoi
10.1155/2012/274851subject
Has Abstractpub_date
2012-01-01 00:00:00pages
274851eissn
2090-0384issn
2090-0392journal_volume
2012pub_type
杂志文章abstract::African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation. The purpose of this study was to determine the effects of a 6-month aerobic exercise training (AEXT) intervention on the inflammatory biomarkers interleukin-10 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:International journal of hypertension
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更新日期:2020-02-28 00:00:00
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journal_title:International journal of hypertension
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更新日期:2011-01-09 00:00:00
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journal_title:International journal of hypertension
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journal_title:International journal of hypertension
pub_type: 杂志文章,评审
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journal_title:International journal of hypertension
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journal_title:International journal of hypertension
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journal_title:International journal of hypertension
pub_type: 杂志文章
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更新日期:2011-01-20 00:00:00
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journal_title:International journal of hypertension
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journal_title:International journal of hypertension
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更新日期:2012-01-01 00:00:00
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更新日期:2013-01-01 00:00:00
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journal_title:International journal of hypertension
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更新日期:2013-01-01 00:00:00
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journal_title:International journal of hypertension
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更新日期:2020-09-01 00:00:00
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journal_title:International journal of hypertension
pub_type: 杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:International journal of hypertension
pub_type: 杂志文章
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abstract::The spontaneously hypertensive rat model with reduced NO synthesis (SHRLN) shares features with aging and hypertension in humans, among other a severe aortic stiffening. The present in vivo study aimed to compare thoracic (TA) and abdominal (AA) aortic stiffness in the SHRLN (treated 5 weeks with L-NAME), SHR, and nor...
journal_title:International journal of hypertension
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更新日期:2019-03-19 00:00:00
abstract::[This corrects the article DOI: 10.1155/2019/6709817.]. ...
journal_title:International journal of hypertension
pub_type: 已发布勘误
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journal_title:International journal of hypertension
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journal_title:International journal of hypertension
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journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/597906
更新日期:2013-01-01 00:00:00
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