Abstract:
:Objectives. To determine the changes in blood pressure levels and antihypertensive medication use in the postrenal transplantation period compared to pretransplantation one. Methods. A comparative cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital, a national referral hospital in Kenya. Sociodemographic details, blood pressure levels, and antihypertensive medication use before and after renal transplantation were noted. Changes in mean blood pressure levels and mean number of antihypertensive medications after renal transplantation were determined using paired t-test. Results. 85 subjects were evaluated. Mean age was 42.4 (SD ± 12.2) years, with a male : female ratio of 1.9 : 1. Compared to the pretransplant period, significantly lower mean systolic and diastolic blood pressure levels after transplantation were noted (mean SBP 144.5 mmHg versus 131.8 mmHg; mean DBP 103.6 mmHg versus 83.5 mmHg in the pre- and posttransplant periods, respectively, p < 0.001). Mean number of antihypertensive medications also reduced significantly after transplantation, with an average of 3.3 (±1.6) versus 2.1 (±0.9) in the pre- and posttransplant periods, respectively (p < 0.001). Conclusion. There is a significant reduction in blood pressure levels and number of antihypertensive medications used after renal transplantation. The positive impact of renal transplantation on blood pressure control should be confirmed using prospective cohort studies of patients with end stage renal disease who then undergo renal transplantation.
journal_name
Int J Hypertensjournal_title
International journal of hypertensionauthors
Kubo MN,Kayima JK,Were AJ,Ezzi MS,McLigeyo SO,Ogola ENdoi
10.1155/2016/8450596subject
Has Abstractpub_date
2016-01-01 00:00:00pages
8450596eissn
2090-0384issn
2090-0392journal_volume
2016pub_type
杂志文章abstract::The brain renin-angiotensin system (RAS) has been highlighted as having a pathological role in stroke, dementia, and neurodegenerative disease. Particularly, in dementia, epidemiological studies indicate a preventive effect of RAS blockade on cognitive impairment in Alzheimer disease (AD). Moreover, basic experiments ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/169649
更新日期:2012-01-01 00:00:00
abstract:Background:Hypertension imposes stresses on many organs like heart and kidney. However, studies that show the effect of hypertension on the lungs are limited. Objective:To assess pulmonary function status of hypertensive patients aged 30-64 years at Zewditu Memorial Hospital, 2017. Methods:Hospital based comparative ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/5492680
更新日期:2018-11-12 00:00:00
abstract::Sodium transport through various nephron segments is quite important in regulating sodium reabsorption and blood pressure. Among several regulators of this process, insulin acts on almost all the nephron segments and is a strong enhancer of sodium reabsorption. Sodium-proton exchanger type 3 (NHE3) is a main regulator...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/391762
更新日期:2011-01-01 00:00:00
abstract::Our aim was to investigate factors predicting blood pressure (BP) variability during diagnostic cerebral angiography and associations between BP variability and clinical outcomes in patients with acute and subacute ischemic stroke and intracranial artery stenosis. 114 patients with ischemic stroke and intracranial art...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/6214581
更新日期:2020-09-01 00:00:00
abstract::Objective. The purpose of this study was to investigate whether short sleepers (<6 hrs) who worked the non-day-shift were at greater likelihood of reporting hypertension and if these associations varied by individuals' ethnicity. Methods. Analysis was based on the 2010 National Health Interview Survey (NHIS). A total ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2015/697275
更新日期:2015-01-01 00:00:00
abstract::This study examined the relationships between SES and diabetes and hypertension for Korean adults using the Korean National Health and Nutritional Examination Survey. To handle the four dummy dependent variables: Diabetes and Hypertension, Diabetes alone, Hypertension alone, and Diabetes or Hypertension, four differen...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/410794
更新日期:2010-06-21 00:00:00
abstract:Background:Hypertension is a major cardiovascular risk factor that is linked with fatal complications and is an overwhelming global challenge. Primary prevention is a key to control hypertension with identification of major risk factors. This study was aimed at assessing the prevalence and factors associated with hyper...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/9878437
更新日期:2019-05-15 00:00:00
abstract::Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of a...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8163824
更新日期:2018-09-18 00:00:00
abstract::Blood pressure (BP) tracking from childhood to adulthood has two aspects: the ranking stability relative to others over time and the prediction of future values. This study investigates BP tracking in children and adolescents in Germany in the context of hypertension risk factors. BP was measured and analyzed in 2542 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8429891
更新日期:2018-09-26 00:00:00
abstract::Background. Effective antihypertensive treatment depends on patient compliance regarding prescribed medications. We assessed the impact of beliefs related towards antihypertensive medication on blood pressure control in a population-based sample treated for hypertension. Methods. We used data from the Characteristics ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/9385397
更新日期:2019-07-28 00:00:00
abstract::Hypertension is known as the major risk factor for cardiovascular mortality and morbidity. Antihypertensive agents are directed to prevent many of the harmful effects of elevated blood pressure, yet medication nonadherence hinders the effectiveness of these therapies. Nowadays the use of mobile phone has vastly spread...
journal_title:International journal of hypertension
pub_type: 杂志文章,评审
doi:10.1155/2019/9021017
更新日期:2019-04-07 00:00:00
abstract:Aim:The aim of present study was to determine the safety and efficacy of a new renal artery denervation system for treatment of hypertensive patients. Methods:Hypertensive patients with mean office systolic blood pressure ≥150mmHg and ≤180mmHg or an average of 24-hour ambulatory systolic blood pressure ≥145mmHg and ≤1...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/7929706
更新日期:2019-02-14 00:00:00
abstract:Background:Angiopoietin-like protein 3 (ANGPTL3) plays a pivotal role in lipid metabolism and angiogenesis, and there is growing interest regarding the association between ANGPTL3 and coronary artery disease (CAD). This study aims to investigate whether ANGPTL3 levels can be used to predict the future occurrence of maj...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/2980954
更新日期:2020-03-27 00:00:00
abstract:Background:White-coat hypertension (HT), masked HT, HT with white-coat effect, and masked uncontrolled HT are well-recognized problems of over- and undertreatment of high blood pressure in real-life practice. However, little is known about the true prevalence in Thailand. Objectives:To examine the prevalence and chara...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/3261408
更新日期:2020-04-09 00:00:00
abstract::Essential hypertension has a high incidence worldwide, and patients with essential hypertension endure a lifetime of medication, leading to a heavy economic burden on the patient's family and causing serious impacts on the patient's quality of life. Much evidence has demonstrated that acupuncture as an adjunctive ther...
journal_title:International journal of hypertension
pub_type: 杂志文章,评审
doi:10.1155/2019/8676490
更新日期:2019-03-07 00:00:00
abstract:Objective:There is poor adherence to antihypertensive therapies among women in India. To determine its socioeconomic barriers we performed a qualitative study on Indian rural women with hypertension. Methods:In-depth interviews with women having hypertension and presenting to outpatient department at a teaching hospit...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2019/5749648
更新日期:2019-01-23 00:00:00
abstract:Background:Epoxide hydrolase 2 (EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of hypertension. Objectives:We aimed to assess the association of a missense mutation, R287Q, in EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/2351547
更新日期:2020-02-28 00:00:00
abstract:Introduction:Hypertension, particularly pulse pressure [PP] is a major risk factor for end-stage renal disease. However, the effect of individual components of hypertension namely PP, systolic [SBP] and diastolic blood pressure [DBP] on kidney function, in the general African population is unknown. Methods:Data were c...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/7864564
更新日期:2018-10-04 00:00:00
abstract::Introduction. Dahl salt-resistant (SR) animal models are similar to peritoneal dialysis patients with fluid volumes overload with normal blood pressure in hemodynamic profiles. We will verify the roles of UII in the regulation of blood pressure in these animal models. Methodology. The Dahl salt-sensitive (SS) and SR r...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2016/9146870
更新日期:2016-01-01 00:00:00
abstract::Increasing blood pressure has a continuum of adverse risk for cardiovascular events. Traditionally this single measure was used to determine who to treat and how vigorously. However, estimating absolute risk rather than measurement of a single risk factor such as blood pressure is a superior method to identify who is ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/595791
更新日期:2011-01-01 00:00:00
abstract::We report on the first survey of hypertension in undergraduates in Sierra Leone. Levels of hypertension (12%) and obesity (4%) appear low compared to the general population but given the rapid increase of both and the expectation that many graduates will enter the formal employment sector and a sedentary lifestyle, th...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2017/8196362
更新日期:2017-01-01 00:00:00
abstract::We investigated the relationship between renal function, blood pressure variability (BPV), and nitric oxide (NO) in a group of African Americans with normal or mildly impaired renal function. 24-hour ambulatory blood pressure monitoring was performed, NO measured, and glomerular filtration rate (GFR) calculated in 38 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/137206
更新日期:2011-01-09 00:00:00
abstract::It has been previously documented that carotid intima-media thickness (cIMT) is a predictor of cardiovascular disease. The aim of this study was to identify clinical parameters associated with an increased cIMT treated hypertensive women. Female patients (n = 116) with essential hypertension, aged 40-65 years, were in...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/257501
更新日期:2012-01-01 00:00:00
abstract:Background:Given that hypertension in adulthood has its onset in childhood, it is not surprising that the prevalence of hypertension among adolescents has also increased in recent years. However, there are limited data on the prevalence of hypertension and also the new AAP guideline has not yet been applied to the Indo...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/4262034
更新日期:2020-09-16 00:00:00
abstract::Mitochondrial dysfunction is implicated in many cardiovascular diseases, including hypertension, and may be associated with an overactive renin-angiotensin system (RAS). Angiotensin (Ang) II, a potent vasoconstrictor hormone of the RAS, also impairs baroreflex and mitochondrial function. Most deleterious cardiovascula...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/136028
更新日期:2013-01-01 00:00:00
abstract::Sympathetic activation in chronic renal failure (CRF) is a major mechanism leading to the progression of renal disease and hypertension. In the present study, we tested the hypothesis that in CRF increased reactive oxygen species (ROS) production in the RVLM mediated by enhanced circulating Angiotensin II (Ang II) is ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/219358
更新日期:2011-01-04 00:00:00
abstract::Hypertension frequently complicates chronic kidney disease (CKD), with studies showing clinical benefit from blood pressure lowering. Subgroups of patients with severe hypertension exist. We aimed to identify patients with the greatest mortality risk from uncontrolled hypertension to define the prevalence and phenotyp...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/597906
更新日期:2013-01-01 00:00:00
abstract::Objective. This study aimed to assess the prevalence and associated factors of hypertension in newly declared municipalities of Kathmandu, Nepal. Design, Settings, and Participants. This was a community-based cross-sectional study conducted in the municipalities of Kathmandu District, Nepal, between January and July 2...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2016/1656938
更新日期:2016-01-01 00:00:00
abstract::Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and centra...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2015/742658
更新日期:2015-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2019/6709817.]. ...
journal_title:International journal of hypertension
pub_type: 已发布勘误
doi:10.1155/2019/2907675
更新日期:2019-10-13 00:00:00