Abstract:
:The aim of this study was to establish whether an independent relationship exists between CD4 count and hypertension and if this relationship is modified or confounded by the body mass index (BMI). Methods. A secondary data analysis of a cross-sectional study on 200 HIV/AIDS patients at a referral hospital in Cameroon was conducted. Linear and logistic regression models were used as appropriate to explore the association between the variables of interest. Results. There was no linear association between log CD4 count and both systolic (p = 0.200; r = 0.12) and diastolic blood pressures (p = 0.123; r = 0.14), respectively. After adjusting for BMI, patients with CD4 count ≥ 350 cells/μl were more likely to have hypertension than those with CD4 count < 350 cells/μl (AOR: 2.50, 95% CI: 1.05-5.93, and p = 0.032). There was no effect modification from BMI (test of homogeneity, p = 0.721). There was no independent relationship between CD4 count and hypertension after controlling for age, sex, family history of hypertension, BMI-defined overweight, HAART use, and duration of HIV infection (AOR: 1.66, 95% CI: 0.48-5.71, and p = 0.419). Conclusion. This study did not identify any independent relationship between CD4 count and hypertension. Large prospective studies are recommended to better explore this relationship between hypertension and CD4 count.
journal_name
Int J Hypertensjournal_title
International journal of hypertensionauthors
Dimala CA,Kadia BM,Kemah BL,Tindong M,Choukem SPdoi
10.1155/2018/1691474subject
Has Abstractpub_date
2018-01-22 00:00:00pages
1691474eissn
2090-0384issn
2090-0392journal_volume
2018pub_type
杂志文章abstract::Accumulating evidence from animal models and human studies of essential hypertension suggest that brain regulation of the vasculature is impacted by the disease. Human neuroimaging findings suggest that the brain may be an early target of the disease. This observation reinforces earlier research suggesting that psycho...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/701385
更新日期:2012-01-01 00:00:00
abstract::Objectives. To determine the changes in blood pressure levels and antihypertensive medication use in the postrenal transplantation period compared to pretransplantation one. Methods. A comparative cross-sectional study was carried out on renal transplant recipients at the Kenyatta National Hospital, a national referra...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2016/8450596
更新日期:2016-01-01 00:00:00
abstract:Background:Angiopoietin-like protein 3 (ANGPTL3) plays a pivotal role in lipid metabolism and angiogenesis, and there is growing interest regarding the association between ANGPTL3 and coronary artery disease (CAD). This study aims to investigate whether ANGPTL3 levels can be used to predict the future occurrence of maj...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/2980954
更新日期:2020-03-27 00:00:00
abstract::Essential hypertension has a high incidence worldwide, and patients with essential hypertension endure a lifetime of medication, leading to a heavy economic burden on the patient's family and causing serious impacts on the patient's quality of life. Much evidence has demonstrated that acupuncture as an adjunctive ther...
journal_title:International journal of hypertension
pub_type: 杂志文章,评审
doi:10.1155/2019/8676490
更新日期:2019-03-07 00:00:00
abstract:Background:Epoxide hydrolase 2 (EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of hypertension. Objectives:We aimed to assess the association of a missense mutation, R287Q, in EPHX2) gene coding for soluble epoxide hydrolase is a potential candidate in the pathogenesis of...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/2351547
更新日期:2020-02-28 00:00:00
abstract:Background:White-coat hypertension (HT), masked HT, HT with white-coat effect, and masked uncontrolled HT are well-recognized problems of over- and undertreatment of high blood pressure in real-life practice. However, little is known about the true prevalence in Thailand. Objectives:To examine the prevalence and chara...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/3261408
更新日期:2020-04-09 00:00:00
abstract:Objectives:Prevalence of hypertension has not been studied in the Ethiopian HIV-infected population, which represents 60% of the patients in our AIDS unit. Our aim was to identify risk factors and characterize the prevalence of hypertension in the population monitored at our unit. Methods:A retrospective chart review ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8637101
更新日期:2018-01-29 00:00:00
abstract::Organic nitrates are a group of very effective anti-ischemic drugs. They are used for the treatment of patients with stable angina, acute myocardial infarction, and chronic congestive heart failure. A major therapeutic limitation inherent to organic nitrates is the development of tolerance, which occurs during chronic...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/842632
更新日期:2012-01-01 00:00:00
abstract::Myocardial fibrosis is characterized by excessive deposition of myocardial interstitial collagen, abnormal distribution, and excessive proliferation of fibroblasts. According to the researches in recent years, myocardial fibrosis, as the pathological basis of various cardiovascular diseases, has been proven to be a co...
journal_title:International journal of hypertension
pub_type: 杂志文章,评审
doi:10.1155/2020/3014693
更新日期:2020-01-31 00:00:00
abstract::Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and centra...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2015/742658
更新日期:2015-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2019/6709817.]. ...
journal_title:International journal of hypertension
pub_type: 已发布勘误
doi:10.1155/2019/2907675
更新日期:2019-10-13 00:00:00
abstract::Angiotensin II increases blood pressure and stimulates thirst and sodium appetite in the brain. It also stimulates secretion of aldosterone from the adrenal zona glomerulosa and epinephrine from the adrenal medulla. The rat has 3 subtypes of angiotensin II receptors: AT1a, AT1b, and AT2. mRNAs for all three subtypes o...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/175428
更新日期:2013-01-01 00:00:00
abstract::Increasing blood pressure has a continuum of adverse risk for cardiovascular events. Traditionally this single measure was used to determine who to treat and how vigorously. However, estimating absolute risk rather than measurement of a single risk factor such as blood pressure is a superior method to identify who is ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/595791
更新日期:2011-01-01 00:00:00
abstract::Hypertension is known as the major risk factor for cardiovascular mortality and morbidity. Antihypertensive agents are directed to prevent many of the harmful effects of elevated blood pressure, yet medication nonadherence hinders the effectiveness of these therapies. Nowadays the use of mobile phone has vastly spread...
journal_title:International journal of hypertension
pub_type: 杂志文章,评审
doi:10.1155/2019/9021017
更新日期:2019-04-07 00:00:00
abstract:Background:Hypertension remains a cause of morbidity and mortality in the Ashanti Region of Ghana. It has been featured in the top ten causes of OPD attendance, admissions, and deaths since 2012. We investigated the sociodemographic characteristics and spatial distribution of inpatient hypertensives and factors associa...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2017/6537956
更新日期:2017-01-01 00:00:00
abstract::We investigated the effects of resistance exercise under hypoxia on postexercise hemodynamics in eight healthy young males. The subjects belonged to a track & field club (sprinters, hurdlers, and long jumpers) and engage in regular physical training (1-2 h per day, 3-5 days per week). Each participant performed eight ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/1456972
更新日期:2018-07-26 00:00:00
abstract::Hypertension frequently complicates chronic kidney disease (CKD), with studies showing clinical benefit from blood pressure lowering. Subgroups of patients with severe hypertension exist. We aimed to identify patients with the greatest mortality risk from uncontrolled hypertension to define the prevalence and phenotyp...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/597906
更新日期:2013-01-01 00:00:00
abstract::Sodium transport through various nephron segments is quite important in regulating sodium reabsorption and blood pressure. Among several regulators of this process, insulin acts on almost all the nephron segments and is a strong enhancer of sodium reabsorption. Sodium-proton exchanger type 3 (NHE3) is a main regulator...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/391762
更新日期:2011-01-01 00:00:00
abstract::This study aimed to determine the prevalence of Self-Monitoring Blood Pressure amongst people with hypertension using a cross-sectional survey. Of the 955 who replied (53%), 293 (31%) reported that they self-monitored blood pressure. Nearly 60% (198/331) self-monitored at least monthly. Diabetic patients monitoring th...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/582068
更新日期:2012-01-01 00:00:00
abstract::Silent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. There is a body of evidence that supports the idea that WMLs in asymptomatic hypertensive ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/478710
更新日期:2011-01-01 00:00:00
abstract::The brain renin-angiotensin system (RAS) has been highlighted as having a pathological role in stroke, dementia, and neurodegenerative disease. Particularly, in dementia, epidemiological studies indicate a preventive effect of RAS blockade on cognitive impairment in Alzheimer disease (AD). Moreover, basic experiments ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/169649
更新日期:2012-01-01 00:00:00
abstract::Hypertension remains a public health burden despite advances in its management. Hence, the search for further risk stratification tools and prevention and new treatment approaches continues. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is associated with hypertension. Interestingly, riboflavin, as a ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/4267246
更新日期:2020-02-13 00:00:00
abstract::Our aim was to investigate factors predicting blood pressure (BP) variability during diagnostic cerebral angiography and associations between BP variability and clinical outcomes in patients with acute and subacute ischemic stroke and intracranial artery stenosis. 114 patients with ischemic stroke and intracranial art...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2020/6214581
更新日期:2020-09-01 00:00:00
abstract::Alterations in the autonomic cardiovascular control have been implicated to play an important etiologic role in preeclampsia. The present study was designed to evaluate autonomic functions in preeclamptic pregnant women and compare the values with normotensive pregnant and healthy nonpregnant controls. Assessment of a...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2018/8163824
更新日期:2018-09-18 00:00:00
abstract::In 2005, the International Society of Nephrology (ISN) established the Global Outreach Program (GO) aimed at building a capacity for detecting and managing chronic kidney disease and its complications in low- and middle-income countries. Here we report data from the 2006-2007 screening program (1025 subjects from the ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2012/951734
更新日期:2012-01-01 00:00:00
abstract::Aim. To evaluate whether body fat distribution, birth weight, and family history for diabetes (FHD) were associated with metabolic syndrome (MetS) in children and adolescents. Methods. A total of 439 Italian obese children and adolescents (5-18 years) were enrolled. Subjects were divided into 2 groups: prepubertal and...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2011/257168
更新日期:2011-02-22 00:00:00
abstract::Mitochondrial dysfunction is implicated in many cardiovascular diseases, including hypertension, and may be associated with an overactive renin-angiotensin system (RAS). Angiotensin (Ang) II, a potent vasoconstrictor hormone of the RAS, also impairs baroreflex and mitochondrial function. Most deleterious cardiovascula...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/136028
更新日期:2013-01-01 00:00:00
abstract::This study examined the relationships between SES and diabetes and hypertension for Korean adults using the Korean National Health and Nutritional Examination Survey. To handle the four dummy dependent variables: Diabetes and Hypertension, Diabetes alone, Hypertension alone, and Diabetes or Hypertension, four differen...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/410794
更新日期:2010-06-21 00:00:00
abstract::African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation. The purpose of this study was to determine the effects of a 6-month aerobic exercise training (AEXT) intervention on the inflammatory biomarkers interleukin-10 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.1155/2013/538017
更新日期:2013-01-01 00:00:00
abstract::We investigated the relationship between renal function, blood pressure variability (BPV), and nitric oxide (NO) in a group of African Americans with normal or mildly impaired renal function. 24-hour ambulatory blood pressure monitoring was performed, NO measured, and glomerular filtration rate (GFR) calculated in 38 ...
journal_title:International journal of hypertension
pub_type: 杂志文章
doi:10.4061/2010/137206
更新日期:2011-01-09 00:00:00