A case of Klinefelter's syndrome with type 1 diabetes mellitus.

abstract：OBJECTIVE:To study the histopathological changes of relevant internal organs of Macaca mulatta infected with Plasmodium knowlesi (P. knowlesi). METHODS:Histopathological examination of 3 monkeys who died of P. knowlesi infection, 2 P. knowlesi infected monkeys who died of treatment failure with artesunate suppository ...

journal_title：Chinese medical journal

authors： Chen L,Li G,Lu Y,Luo Z

更新日期：2001-10-01 00:00:00

abstract：:102 patients with nasal polyps receiving ND: YAG laser surgery or routine surgery were followed up for 18-36 months. The postoperative recurrence rates were 40.6% (24/54) and 66.6% (32/48) respectively for the patients of the two groups. Laser surgery is marked by less bleeding, no postoperative packing of the nose an...

journal_title：Chinese medical journal

authors： Zhang BQ

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Prostate specific membrane antigen (PSMA) can facilitate the growth, migration, and invasion of the LNCaP prostate cancer cell lines, but the underlying molecular mechanisms have not yet been clearly defined. Here, we investigated whether PSMA serves as a novel regulator of the phosphatidylinositol 3-kinase ...

journal_title：Chinese medical journal

authors： Guo Z,Lai Y,Du T,Zhang Y,Chen J,Bi L,Lin T,Liu H,Wang W,Xu K,Jiang C,Han J,Zhang C,Dong W,Huang J,Huang H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Tbx1 is the major candidate gene for DiGeorge syndrome (DGS). Similar to defects observed in DGS patients, the structures disrupted in Tbx1(-/-) animal models are derived from the neural crest cells during development. Although the morphological phenotypes of some Tbx1 knock-down animal models have been well...

journal_title：Chinese medical journal

authors： Zhang LF,Gui YH,Wang YX,Jiang Q,Song HY

更新日期：2010-05-05 00:00:00

abstract：BACKGROUND:The effects of near-road pollution on lung function in China have not been well studied. We aimed to investigate the effects of long-term exposure to traffic-related air pollution on lung function, airway inflammation, and respiratory symptoms. METHODS:We enrolled 1003 residents aged 57.96 ± 8.99 years livi...

journal_title：Chinese medical journal

authors： Hu ZW,Zhao YN,Cheng Y,Guo CY,Wang X,Li N,Liu JQ,Kang H,Xia GG,Hu P,Zhang PJ,Ma J,Liu Y,Zhang C,Su L,Wang GF

更新日期：2016-09-20 00:00:00

abstract：OBJECTIVE:To investigate the mechanism of multidrug resistance (MDR) in a human glioma cell and methods for overcoming multi-drug resistance. METHODS:MDR cell line C(6)/adr was established. The expression of the mdr-1 gene and its P-glycoprotein (P-gp) in the C(6)/adr cell line was observed by RT-PCR and flow cytometr...

journal_title：Chinese medical journal

authors： Liu F,Wang C,Zhang Q,Li J,Zhang Y

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The myocardial ATP sensitive potassium channel (K(ATP) channel) has been known for more than two decades, the properties of this channel have been intensively investigated, especially the myocardial protection effect by opening this channel. Numerous studies, including hypothermic, using K(ATP) agonists to a...

journal_title：Chinese medical journal

authors： Jin SQ,Niu LJ,Deng CY,Yao ZB,Zhou YJ

更新日期：2006-10-20 00:00:00

abstract：BACKGROUND:Although there are several drugs and drug combinations for the treatment of Pneumocystis carinii (P. carinii) pneumonia, all drugs have the toxicity as well as low efficacy. Iron chelators have been proposed as a source of new drugs for combating these infections. We hypothesized that iron chelators would su...

journal_title：Chinese medical journal

authors： Ye B,Zheng YQ,Wu WH,Zhang J

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The molecular mechanisms underlying the endometriosis are still not completely understood. In order to test the hypothesis that the approaches in phosphoproteomics might contribute to the identification of key biomarkers to assess disease pathogenesis and drug targets, we carried out a phosphoproteomics anal...

journal_title：Chinese medical journal

authors： Xu HM,Deng HT,Liu CD,Chen YL,Zhang ZY

更新日期：2015-10-05 00:00:00

abstract：OBJECTIVE:To measure serum 7S collagen (7S-C) and type VI collagen (VI-C) levels by radioimmunoassay (RIA) in Chinese patients with various liver disorders and in CCl4-treated SD rats, and to investigate the significance of the elevated levels of serum 7S-C and VI-C. METHODS:Serum 7S-C and VI-C levels were measured in...

journal_title：Chinese medical journal

authors： Ji X,Li S,Kong X,Xu G,Chen J,Dai X

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Intratracheal instillation of blood induces self-repaired acute lung injury. However, the mechanism of repair has been unclear. Heme-oxygenase (HO)-1, which catalyzes heme breakdown, acts as an inducible defense against oxidative stress and plays an important role in inflammation. The objective of this study...

journal_title：Chinese medical journal

authors： Pang QF,Zhou QM,Zeng S,Dou LD,Ji Y,Zeng YM

更新日期：2008-09-05 00:00:00

abstract：:The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widene...

journal_title：Chinese medical journal

authors： Dai LY,Jia LS

更新日期：1994-06-01 00:00:00

abstract：:In this study, we observed the endotoxin induced platelet aggregation, 5-HT and beta-g releases, cellular cAMP decrease, and also the changes of morphology and membrane fluidity of platelet. These changes play an important role in septic shock, especially in disseminated intravascular coagulation (DIC) and respiratory...

journal_title：Chinese medical journal

authors： Xu SH,Zhu GJ,Wu QX,Chen HC

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Roux-en-Y gastric bypass (GBP) is the main surgical procedure used in type 2 diabetes. The objective of this study was to evaluate the different types of GBP in treatment of type 2 diabetes. METHODS:Patients with type 2 diabetes were randomly divided into two groups: those who underwent gastrojejunal loop a...

journal_title：Chinese medical journal

authors： Pu YD,Li JQ,Cao ZY,Wang L,Hu X,Dong LG,Li YM,Zhao HZ,Qin R,Yang B,He JM,Wu YJ,Wang Y,Lü G,Zhang B,Wang Y,Liu WP,Weng JF

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Postoperative preablative stimulated thyroglobulin (ps-Tg) has been evaluated in predicting prognosis and success of ablation regarding differentiated thyroid cancer (DTC); however, its relationship with recurrence risk and radioiodine decision-making remains uncertain, especially in Chinese DTC patients. We...

journal_title：Chinese medical journal

authors： Yang X,Liang J,Li TJ,Yang K,Liang DQ,Yu Z,Lin YS

更新日期：2015-04-20 00:00:00

abstract：BACKGROUND:Surgical resection is generally considered the main curative treatment for intrahepatic biliary cystadenocarcinoma (IBCA) or suspected IBCAs, but controversy exists regarding the prognosis for IBCAs. This study aimed to describe the clinicopathological characteristics of IBCA and identify prognostic factors ...

journal_title：Chinese medical journal

authors： Xu MY,Shi XJ,Wan T,Liang YR,Wang HG,Zhang WZ,He L,Chen MY,Lyu SC,Zhang WW,Li HX

更新日期：2015-05-05 00:00:00

abstract：:The long-term results of total meniscectomy in 60 patients were reviewed. The patients were followed up to 10 to 33 years. 58.3% of the patients had excellent or good results. Statistical analysis showed that the late results were related to the time of follow-up and not associated with the duration of disease before ...

journal_title：Chinese medical journal

authors： Dai L,Zhang W,Zhou Z,Xu Y

更新日期：1995-08-01 00:00:00

abstract：:The effects of the extracts of 20 Chinese medicinal herbs and an antiviral drug foscarnet on duck hepatitis B virus (DHBV) endogenous DNA polymerase (DNAp) activity were compared. The extracts of P. urinaria showed a dose-dependent inhibition on DHBV DNAp. And those of other herbs showed little inhibition effect. Prim...

journal_title：Chinese medical journal

authors： Mi Z,Chen H,Zhang X,Shao X,Li Z,Wu X

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To summarize the progress of surgical treatment of hepatocellular carcinoma (HCC) and related basic research at the Liver Cancer Institute of Shanghai Medical University in the recent years, with special reference to recurrence and metastasis. METHODS:Published and unpublished update clinical and experimenta...

journal_title：Chinese medical journal

authors： Tang Z,Zhou X,Lin Z,Yang B,Ma Z,Ye S,Wu Z,Fan J,Liu Y,Liu K,Qin L,Tian J,Sun H,He B,Xia J,Qiu S,Zhou J

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVE:To study the preventive effect of artemether (Art) in protecting the people from schistosome infection during flood fighting in schistosomiasis endemic area of Poyang Lake, Jiangxi Province. METHODS:From mid July to mid August in 1996, the water level in Poyang Lake rose due to torrential rains and 2 embankm...

journal_title：Chinese medical journal

authors： Song Y,Xiao S,Wu W,Zhang S,Xie H,Xu X,Hu X,Cui Q,Chen M,Zheng J

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Preeclampsia, characterized by hypertension and proteinuria, is a multifactorial disease associated with shallow invasion of trophoblast cells and inadequate spiral artery remodeling. Trophoblast and tumor cells have similar invasion mechanism. Prostasin is closely related to tumor development, invasion and ...

journal_title：Chinese medical journal

authors： Luo D,Zhang Y,Bai Y,Liu X,Gong Y,Zhou B,Zhang L,Luo L,Zhou R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To review the advances of studies on vitamin D receptor and its role in the pathogenesis of diabetic nephropathy. DATA SOURCES:A comprehensive search of the PubMed literatures without restriction on the publication date was carried out using keywords such as vitamin D receptor and diabetic nephropathy. STUD...

journal_title：Chinese medical journal

authors： Guan X,Yang H,Zhang W,Wang H,Liao L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:In China the ginseng root began to be used in medicine over 2000 years ago. Ginsenosides are the most important component isolated from ginseng. The authors investigated the effect of ginsenoside Rg1 on the spectrum of gene expression in the endothelial cells stimulated by TNF-alpha and further explored the ...

journal_title：Chinese medical journal

authors： Lü JP,Ma ZC,Yang J,Huang J,Wang SR,Wang SQ

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To study the mode of presentation, the tumor, nodes, metastasis (TNM) staging and the efficacy of multimodal treatment of breast cancer among Chinese women treated in Queen Mary Hospital. METHODS:The available records of all breast cancer patients treated between January 1980 and December 1994 were reviewed....

journal_title：Chinese medical journal

authors： Chow LW,Ting AC,Cheung KL,Au GK,Alagaratnam TT

更新日期：1997-06-01 00:00:00

abstract：:The depth and area-percentage of Alcian blue (AB) staining of glomeruli, the ability of RBC to bind AB and the onset of proteinuria in adriamycin nephrosis in rats were studied. The results showed that the negative charge (NC) on RBC and glomeruli decreased significantly after injection of adriamycin and there was a p...

journal_title：Chinese medical journal

authors： Chen ZY,Jiang XY

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVE:The objective was to provide a brief history of J wave syndromes and to summarize our current understanding of their molecular, ionic, cellular mechanisms, and clinical features. We will also discuss the existing debates and further direction in basic and clinical research for J wave syndromes. DATA SOURCES:...

journal_title：Chinese medical journal

authors： Li GL,Yang L,Cui CC,Sun CF,Yan GX

更新日期：2015-04-05 00:00:00

abstract：Background:Patients with major depressive disorder (MDD) usually have high risk of suicidality. Few studies have investigated the effects of stressful life events (SLEs) on the risk of suicide in Chinese patients who have developed MDD. This study aimed to investigate the impact of SLEs on suicidal risk in Chinese pati...

journal_title：Chinese medical journal

authors： Lin JY,Huang Y,Su YA,Yu X,Lyu XZ,Liu Q,Si TM

更新日期：2018-04-20 00:00:00

abstract：OBJECTIVE:To review the implications for diagnosis, pathogenesis and potential for new therapeutic option for chronic neutrophilic leukemia (CNL). DATA SOURCES:Data cited in this review were obtained mainly from PubMed and Medline from 1993 to 2013 and highly regarded older publications were also included. The terms "...

journal_title：Chinese medical journal

authors： Otgonbat A,Zhao M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate changes in intestinal microflora in patients with chronic severe hepatitis (CSH), and their role in this life-threatening disease. METHODS:We classified nineteen patients with chronic severe hepatitis as the CSH group, thirty patients with chronic hepatitis (CH) as the CH group and thirty-one ...

journal_title：Chinese medical journal

authors： Li L,Wu Z,Ma W,Yu Y,Chen Y

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To explore the methods of lens-sparing (without lensectomy), non-silicone oil tamponade and no scleral buckling for treatment of early giant retinal tears. METHODS:Thirteen cases of early retinal detachment of proliferative vitreoretinopathy (PVR) grade C2-D1, with giant tear extending from 135 degrees to 27...

journal_title：Chinese medical journal

authors： Xu X,Zhang X,Wu N,Ho PC

更新日期：1999-03-01 00:00:00