A preliminary study of the inhibiting mechanism of anisodamine on rabbit platelets activated by E. coli endotoxin.

abstract：OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

journal_title：Chinese medical journal

authors： Zhou Z,Li L,Yu Y,Ma Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Antiphospholipid syndrome (APS)-related immune factors are considered as an important cause of recurrent spontaneous abortion (RSA). Anticoagulant and anti-inflammatory treatments are believed to effectively improve adverse pregnancy outcomes by affecting the abnormal autoimmune response of the maternal-feta...

journal_title：Chinese medical journal

authors： Ye SL,Gu XK,Tao LY,Cong JM,Wang YQ

更新日期：2017-06-20 00:00:00

abstract：BACKGROUND:The Medtronic InSync Sentry is the first available cardiac resynchronization therapy defibrillator (CRT-D) which can monitor fluid status by measuring intrathoracic impedance. This study was designed to observe the effectiveness of intrathoracic impedance monitoring on detecting aggravation of heart failure....

journal_title：Chinese medical journal

authors： Qiao Q,Hua W,Ding LG,Chen KP,Wang J,Wang FZ,Zhang S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Most cardiac regenerative approaches can restore injured heart muscles. In this study, we investigated if fibrin sealant could help neonatal cardiomyocytes restore myocardial function in a rat model of myocardial infarction. METHODS:The left anterior descending artery in adult female Sprague-Dawley (SD) rat...

journal_title：Chinese medical journal

authors： Li YS,Gao BR

更新日期：2007-11-20 00:00:00

abstract：:100 women ranging in age from 26-34 years were followed up for 4-21 months after undergoing sterilization by tubal occlusion using intraluminal threads and silver clips. The number of children/woman ranged from 1-5 with 80% having 2. 31 women underwent sterilization postmenstrually, 11 midmenstrually, 28 premenstrua...

journal_title：Chinese medical journal

authors： Ding SL

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The patients with unprotected left main coronary artery (ULMCA) stenosis and chronic total occlusion (CTO) lesions at the left anterior descending (LAD) artery are often recommended for bypass surgery. However, some of these patients are deemed inoperable or are at high risk for surgery. In this study, we ex...

journal_title：Chinese medical journal

authors： Yang GT,Han YL,Jing QM,Wang SL,Li Y,Ma YY,Wang G,Luan B,Wang XZ,Wang B,Wang ZL,Wang DM

更新日期：2010-04-05 00:00:00

abstract：:Apolipoprotein (a) [Lp(a)] phenotypes of 69 myocardial infarction survivor and 56 stroke patients were reported and compared to those of 190 healthy Chinese. The results revealed that the distributions of apo(a) phenotype frequency in patients with cardio-cerebrovascular disease (CCVD) were different from those of con...

journal_title：Chinese medical journal

authors： Zhuang YY,Li JJ,Wang JJ

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:To investigate the role of bax in a vincristine (VCR)-induced multidrug-resistant (MDR) human gastric cancer cell line, SGC7901/VCR, in which the Bax protein expression level was significantly lower compared with that in parent cells. METHODS:A bax eukaryotic expression vector was constructed and transfected...

journal_title：Chinese medical journal

authors： Zhao Y,Xiao B,Chen B,Qiao T,Fan D

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The most typical cardiac abnormality is conotruncal defects (CTDs) in patients with 22q11 deletion syndrome (22q11DS). HIRA (histone cell cycle regulator) gene, as one of the candidate genes located at the critical region of 22q11DS, was reported as possibly relevant to CTD in animal models. This study aimed...

journal_title：Chinese medical journal

authors： Ju ZR,Wang HJ,Ma XJ,Ma D,Huang GY

更新日期：2016-10-20 00:00:00

abstract：BACKGROUND:Primary systemic light chain amyloidosis (AL) is a rare plasma cell disease, our purpose was to analyze the immunophenotypic characteristics of the plasma cells in bone marrow in AL patients, and explore whether the detection of abnormal plasma cell clones in bone marrow by flow cytometry (FCM) could be used...

journal_title：Chinese medical journal

authors： Hu Y,Wang M,Chen Y,Chen X,Fang F,Liu S,Zhang Y,Wu X,Zhu P

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To determine antiganglioside antibodies (AGA) in cerebrospinal fluid (CSF) of children with neuropsychiatric lupus erythematosus (NPLE), and to investigate their association with clinical manifestations and other laboratory tests. METHODS:An enzyme linked immunoabsorbent assay was used to detect AGA in 22 CS...

journal_title：Chinese medical journal

authors： Chen Y,Wu F,Hou L,Ma S,He X

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Whether antibody to myelin oligodendrocyte glycoprotein (MOG) can be a diagnostic marker for multiple sclerosis (MS) is still controversial. Recent studies suggested that serum specific anti-MOG epitope antibody might be an MS specific marker. However, these studies did not include neuromyelitis optica (NMO)...

journal_title：Chinese medical journal

authors： Xu Y,Zhang Y,Liu CY,Peng B,Wang JM,Zhang XJ,Li HF,Cui LY

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To study the status of cochlear mitochondrial DNA (mtDNA) and to determine the location of mtDNA deletion in aged mice. METHODS:We detected cochlear mtDNA in 2, 7 - 10 and 17 - 19 month old mice by nested polymerase chain reaction (PCR) and DNA sequencing. RESULTS:mtDNA3867bp deletions were found in the co...

journal_title：Chinese medical journal

authors： Zhang X,Han D,Ding D,Dai P,Yang W,Jiang S,Salvi RJ

更新日期：2002-09-01 00:00:00

abstract：:Ten Chinese Leishmania isolates from different endemic areas and hosts are characterized by isoenzyme electrophoresis for 9 enzymes. Seven were isolated from visceral leishmaniasis patients, one from an infected dog, one from a sandfly and one from a naturally infected racoon dog. Eight of the 10 isolates were indisti...

journal_title：Chinese medical journal

authors： Xu ZB,Liu ZT,Long JY,Chai JJ,Chen WK

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Although previous reports had reported the use of temporary internal distraction as an aid to correct severe scoliosis, two-stage surgery strategy (less invasive internal distraction followed by posterior correction and instrumentation) has never been reported in the treatment of patients with severe spinal ...

journal_title：Chinese medical journal

authors： Tan R,Ma HS,Zou DW,Wu JG,Chen ZM,Zhou XF,Zhou JW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The risk of clinical deterioration still exists in the acute phase despite the fact that patients with minor stroke may display less severe symptoms. The impact of this clinical deterioration on long-term outcomes is unknown. We characterized the clinical features of neurological deterioration (ND) in the ac...

journal_title：Chinese medical journal

authors： Ju Y,Zhao XQ,Wang CX,Wang YL,Liu GF,Wang YJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Combination paclitaxel and carboplatin is currently a first-line regimen for ovarian cancer. However, many patients develop tumor recurrence or drug resistance to this regimen. The study aims to investigate the effectiveness and safety of an oxaliplatin + epirubicin + ifosfamide regimen for the treatment of ...

journal_title：Chinese medical journal

authors： Zhang G,Li XP,Liu BJ,Wang JL,Wang SJ,Cui H,Wei LH

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence and features of active human cytomegalovirus (HCMV) infection in children with systemic lupus erythematosus (SLE) and evaluate the diagnostic value of the HCMV using antigenemia assay, serum polymerase chain reaction (PCR) and serology test. METHODS:Twenty-one SLE children under...

journal_title：Chinese medical journal

authors： Zhang C,Shen K,Jiang Z,He X

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Myocardial apoptosis is involved in the pathogenesis of sepsis-related myocardial depression. However, the underlying mechanism remains unknown. This study investigated the role of mitochondrial damage and mitochondria-induced oxidative stress during cardiac apoptosis in septic rats. METHODS:Seventy-two Spr...

journal_title：Chinese medical journal

authors： Li L,Hu BC,Chen CQ,Gong SJ,Yu YH,Dai HW,Yan J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The offspring of women with gestational diabetes mellitus (GDM) are prone to macrosomia. However, birth weight is difficult to be correctly estimated by ultrasound because of fetal asymmetric growth characteristics. This study aimed to investigate the correlations between fetal hemodynamics, fetal growth ind...

journal_title：Chinese medical journal

authors： Liu F,Liu Y,Lai YP,Gu XN,Liu DM,Yang M

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:As a Chinese Traditional Medicine product, Kuntai capsule could improve the peri-menopausal symptoms in postmenopausal women. But it is still not clear whether Kuntai capsule has a good effect on alleviating peri-menopausal symptoms induced by gonadotropin releasing hormone agonist (GnRH-a) treatment. The pu...

journal_title：Chinese medical journal

authors： Chen JM,Gao HY,Ding Y,Yuan X,Wang Q,Li Q,Jiang GH

更新日期：2015-02-20 00:00:00

abstract：BACKGROUND:It is important to determine prognostic factors for the outcome of amyotrophic lateral sclerosis (ALS) at an early stage. The time taken for symptoms to spread from spinal or bulbar regions to both (time to generalization; TTG) is considered a strong predictor of survival; however, this has rarely been studi...

journal_title：Chinese medical journal

authors： Sun QH,Li YR,Lan WJ,Yang F,Cui F,Huang XS

更新日期：2019-05-05 00:00:00

abstract：BACKGROUND:The change of glucose transporter 4 (GLUT4) expression could influence glucose uptake in the myocardial cells and then effect myocardial metabolism, which maybe one of the factor for the diabetes cardiovascular disease. This study aimed to explore the influence of glucose and insulin at different concentrati...

journal_title：Chinese medical journal

authors： Liu Q,Huang QX,Lou FC,Zhang L,Wang K,Yu S,Xu H,Wang Q,Zhang Y,Hou WK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:One of the major causes of death in severe acute pancreatitis (SAP) is severe infection owing to bacterial translocation. Some clinical studies suggested that ecoimmunonutrition (EIN) as a new strategy had better treatment effect on SAP patients. But the experiment studies on the precise mechanism of the eff...

journal_title：Chinese medical journal

authors： Xu GF,Lu Z,Gao J,Li ZS,Gong YF

更新日期：2006-04-20 00:00:00

abstract：BACKGROUND:A simple, safe and effective therapeutic strategy for traumatic instability of the subaxial cervical spine, as well as its prognostic assessment, is still controversial. METHODS:The therapeutic options for 83 patients of traumatic instability of the subaxial cervical spine, whose average age was 35 years, w...

journal_title：Chinese medical journal

authors： Cao P,Liang Y,Gong YC,Zheng T,Zhang XK,Wu WJ

更新日期：2008-08-05 00:00:00

abstract：:Immunohistochemical and ultrastructural findings in a primary intracranial endodermal sinus tumor are reported in this paper. The tumor cells exhibited AFP, CEA and anti-alpha-1-trypsin positive immunoreactivity immunocytochemically. Aggregates of electron-dense material in the extra- and intracellular spaces and amor...

journal_title：Chinese medical journal

authors： Shi QL,Jin XZ,Zhou XJ,Qian YC,Shi Q

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:To avoid the irritation of tendons and soft tissues as well as hardware-related problems, we designed an intramedullary fixation with bioabsorbable rods for the treatment of the metacarpal shaft fractures. METHODS:Five patients with nine shaft fractures of the fourth and fifth metacarpi were treated with in...

journal_title：Chinese medical journal

authors： Xiong G,Xiao ZR,Guo SG,Zheng W,Dai LF

更新日期：2015-11-05 00:00:00

abstract：BACKGROUND:Vascular rings are uncommon anomalies in which preferred strategies for diagnosis and management may vary among institutions. In this study, we reported our approach and a review of our 5-year experience. METHODS:From May 2006 to April 2011, 45 children (31 boys) with vascular rings underwent surgical repai...

journal_title：Chinese medical journal

authors： Bai S,Li XF,Liu CX,Peng Y,Yuan F,Guo J,Song ZJ,Novick WM,Li ZZ

更新日期：2012-04-01 00:00:00

abstract：:Patients whose routine MRI were negative but were clinically highly suspected of having intra-cranial or intra-spinal canal space-occupying lesions, and those whose routine MRI were positive but presented difficulties in defining the contour or the nature of the lesion, or difficulty in distinguishing the lesion from ...

journal_title：Chinese medical journal

authors： Shen TZ,Mei H,Huang XL,Chen XR

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Our previous studies have shown that regulatory factor X5 (RFX5), a classical transcription regulator of MHCII genes, was obviously overexpressed in hepatocellular carcinoma (HCC) tumors. However, the role of RFX5 in the carcinogenesis and progress of HCC remains unknown. This study aimed to reveal its biolo...

journal_title：Chinese medical journal

authors： Chen DB,Zhao YJ,Wang XY,Liao WJ,Chen P,Deng KJ,Cong X,Fei R,Wu X,Shao QX,Wei L,Xie XW,Chen HS

更新日期：2019-07-05 00:00:00