Chronic fatigue is associated with increased disease-related worries and concerns in inflammatory bowel disease.

abstract：AIM:To investigate the mechanism of chaperone-mediated autophagy (CMA)-induced resistance to irradiation-triggered apoptosis through regulation of the p53 protein in hepatocellular carcinoma (HCC). METHODS:Firstly, we detected expression of lysosome-associated membrane protein 2a (Lamp-2a), which is the key protein of...

journal_title：World journal of gastroenterology

authors： Wu JH,Guo JP,Shi J,Wang H,Li LL,Guo B,Liu DX,Cao Q,Yuan ZY

更新日期：2017-04-07 00:00:00

abstract：AIM:To investigate the relationship between exercise-provoked esophageal motility disorders and the prognosis for patients with chest pain. METHODS:The study involved 63 subjects with recurrent angina-like chest pain non-responsive to empirical therapy with proton pump inhibitor (PPI). In all, a coronary artery angiog...

journal_title：World journal of gastroenterology

authors： Budzyński J

更新日期：2010-09-21 00:00:00

abstract：AIM:To investigate the intestinal anti-inflammatory effect and mechanism of a probiotic Lactobacillus salivarius ssp. salivarius CECT5713 in the TNBS model of rat colitis. METHODS:Female Wistar rats (180-200 g) were used in this study. A group of rats were administered orally the probiotic L. salivarius ssp. salivariu...

journal_title：World journal of gastroenterology

authors： Peran L,Camuesco D,Comalada M,Nieto A,Concha A,Diaz-Ropero MP,Olivares M,Xaus J,Zarzuelo A,Galvez J

更新日期：2005-09-07 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer and has a 5-year survival of < 5%. Only about 15% of the patients present with a resectable PDAC with potential to undergo "curative" surgery. After surgery, local and systemic recurrence, is though very common. The median survival ...

journal_title：World journal of gastroenterology

authors： Ansari D,Gustafsson A,Andersson R

更新日期：2015-03-21 00:00:00

abstract：BACKGROUND:The implementation of optical diagnosis (OD) of diminutive colorectal lesions in clinical practice has been hampered by differences in performance between community and academic settings. One possible cause is the lack of a standardized learning tool. Since the factors related to better learning are not well...

journal_title：World journal of gastroenterology

authors： Bustamante-Balén M,Satorres C,Puchades L,Navarro B,García-Morales N,Alonso N,Ponce M,Argüello L,Pons-Beltrán V

更新日期：2019-03-14 00:00:00

abstract：BACKGROUND:Intestinal inflammation is a common digestive tract disease, which is usually treated with hormone medicines. Hormone medicines are effective to some extent, but long-term use of them may bring about many complications. AIM:To explore the protective effects of panax notoginseng saponin (PNS) against dextran...

journal_title：World journal of gastroenterology

authors： Lu QG,Zeng L,Li XH,Liu Y,Du XF,Bai GM,Yan X

更新日期：2020-03-21 00:00:00

abstract：AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

journal_title：World journal of gastroenterology

authors： Ding LA,Li JS

更新日期：2003-06-01 00:00:00

abstract：:Alcoholic liver disease (ALD) is characterized by steatosis or fat deposition in the liver and inflammation, which leads to cirrhosis and hepatocellular carcinoma. Induction of target genes without involving changes in DNA sequence seems to contribute greatly to liver injury. Chromatin modifications including alterati...

journal_title：World journal of gastroenterology

authors： Mandrekar P

更新日期：2011-05-28 00:00:00

abstract：:A variety of inflammatory diseases of the colon, which can be differentiated from inflammatory bowel disease (IBD) and infectious colitis by their clinical, endoscopic and histological characteristics, are reported as non-IBD and non-infectious colitis. These diseases include microscopic colitis, ischemic colitis, seg...

journal_title：World journal of gastroenterology

authors： Koutroubakis IE

更新日期：2008-12-28 00:00:00

abstract：AIM:To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn's disease (CD) intestinal fibrosis. METHODS:First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and select the optimal conc...

journal_title：World journal of gastroenterology

authors： Yang BL,Zhu P,Li YR,Xu MM,Wang H,Qiao LC,Xu HX,Chen HJ

更新日期：2018-08-14 00:00:00

abstract：AIM:To compare two tests for exocrine pancreatic function (EPF) for use in M-ANNHEIM staging for pancreatitis. METHODS:One hundred and ninety four consecutive patients with acute pancreatitis (AP; n = 13), recurrent acute pancreatitis (RAP; n = 65) and chronic pancreatitis (CP; n = 116) were enrolled. EPF was assessed...

journal_title：World journal of gastroenterology

authors： Kamath MG,Pai CG,Kamath A,Kurien A

更新日期：2017-03-28 00:00:00

abstract：:Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by the intake of pyrrolizidine alkaloids (PAs). To date, PAs-induced HSOS has not been extensively studied. In view of the difference in etiology of HSOS between the West and China, clinical profiles, imaging findings, treatment, and outcomes of HSOS associa...

journal_title：World journal of gastroenterology

authors： Yang XQ,Ye J,Li X,Li Q,Song YH

更新日期：2019-07-28 00:00:00

abstract：:Cholelithiasis occurs infrequently in the paediatric age group. Hereditary spherocytosis, sickle cell anaemia and thalassemia are the haemolytic disorders most commonly associated with development of gall stones in paediatric age group. The question is whether an isolated episode of haemolysis can cause gallstones. ...

journal_title：World journal of gastroenterology

authors： Kejariwal D

更新日期：2006-04-14 00:00:00

abstract：AIM:To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels. METHODS:Ten male patients with HCV-related chronic hepatitis and 16 healthy male volunteers were studied. In all subjects seminal parameters (nemaspermic concentration...

journal_title：World journal of gastroenterology

authors： Durazzo M,Premoli A,Di Bisceglie C,Bertagna A,Faga E,Biroli G,Manieri C,Bo S,Pagano G

更新日期：2006-05-21 00:00:00

abstract：AIM:To investigate anti-apoptotic effects of glycyrrhizic acid (GA) against fibrosis in carbon tetrachloride (CCl4)-induced liver injury and its contributing factors. METHODS:Liver fibrosis was induced by administration of CCl4 for 8 wk. Pathological changes in the liver of rats were examined by hematoxylin-eosin stai...

journal_title：World journal of gastroenterology

authors： Liang B,Guo XL,Jin J,Ma YC,Feng ZQ

更新日期：2015-05-07 00:00:00

abstract：AIM:To investigate the differences in injury patterns caused by arterial, venous or arteriovenous mesenteric occlusion. METHODS:Male Wistar rats were separated equally into four groups. Occlusion was performed by clamping the superior mesenteric artery (A), the mesenteric vein (V) or both (AV) for 30 min, followed by ...

journal_title：World journal of gastroenterology

authors： Guzmán-de la Garza FJ,Cámara-Lemarroy CR,Alarcón-Galván G,Cordero-Pérez P,Muñoz-Espinosa LE,Fernández-Garza NE

更新日期：2009-08-21 00:00:00

abstract：AIM:To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. METHODS:A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclat...

journal_title：World journal of gastroenterology

authors： Hayes SJ,Hng KN,Clark P,Thistlethwaite F,Hawkins RE,Ang Y

更新日期：2014-04-14 00:00:00

abstract：:Bacterial colonization of the gut shapes both the local and the systemic immune response and is implicated in the modulation of immunity in both healthy and disease states. Recently, quantitative and qualitative changes in the composition of the gut microbiota have been detected in Crohn's disease and ulcerative colit...

journal_title：World journal of gastroenterology

authors： Rapozo DC,Bernardazzi C,de Souza HS

更新日期：2017-03-28 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：AIM:To evaluate the association between acid suppressive drug use and the development of gastric cancer. METHODS:A systematic search of relevant studies that were published through June 2012 was conducted using the MEDLINE (PubMed), EMBASE, and Cochrane Library databases. The search included observational studies on t...

journal_title：World journal of gastroenterology

authors： Ahn JS,Eom CS,Jeon CY,Park SM

更新日期：2013-04-28 00:00:00

abstract：:AIM:To clone core gene cDNA of Chinese hepatitis C virus (HCV) into eukaryotic expression vector cosmid pTM3 and to express HCV core antigen in HepG2 cells.METHODS:Core gene cDNA of HCV was introduced into eukaryotic expression vector cosmid pTM3.Using vaccinia virus/bacteriophage T7 hybrid expression system, HepG2 ce...

journal_title：World journal of gastroenterology

authors： Jiang RL,Lu QS,Luo KX

更新日期：2000-04-01 00:00:00

abstract：AIM:To evaluate the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be avoided. METHODS:A total of 324 patients with celiac disease (CD; 97 children and 227 adults) were recruited prospectively at two tertiary cente...

journal_title：World journal of gastroenterology

authors： Vivas S,Ruiz de Morales JG,Riestra S,Arias L,Fuentes D,Alvarez N,Calleja S,Hernando M,Herrero B,Casqueiro J,Rodrigo L

更新日期：2009-10-14 00:00:00

abstract：AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn's disease (CD) and ulcerative colitis (UC). METHODS:The data from 41 patients with CD and 22 patients w...

journal_title：World journal of gastroenterology

authors： Farkas K,Lakatos PL,Szűcs M,Pallagi-Kunstár É,Bálint A,Nagy F,Szepes Z,Vass N,Kiss LS,Wittmann T,Molnár T

更新日期：2014-03-21 00:00:00

abstract：AIM:To evaluate the association of pre-treatment (13)C-urea breath test (UBT) results with H pylori density and efficacy of eradication therapy in patients with active duodenal ulcers. METHODS:One hundred and seventeen consecutive outpatients with active duodenal ulcer and H pylori infection were recruited. H pylori d...

journal_title：World journal of gastroenterology

authors： Lai YC,Yang JC,Huang SH

更新日期：2004-04-01 00:00:00

abstract：AIM:To clarify the pathogenesis of gastroesophageal reflux disease symptoms in non-erosive reflux disease (NERD) patients. METHODS:Thirty-five NERD patients with persistent symptoms, despite taking rabeprazole 10 mg twice daily for at least 8 wk, were included in this study. All patients underwent 24 h combined impeda...

journal_title：World journal of gastroenterology

authors： Nakagawa K,Koike T,Iijima K,Saito M,Kikuchi H,Hatta W,Ara N,Uno K,Asano N,Shimosegawa T

更新日期：2015-12-21 00:00:00

abstract：:Surgical resection offers the best opportunity for survival in patients with colorectal cancer metastatic to the liver, with five-year survival rates up to 58% in selected cases. However, only a minority are resectable at the time of diagnosis. Continuous research in this field aims at increasing the percentage of pat...

journal_title：World journal of gastroenterology

authors： Misiakos EP,Karidis NP,Kouraklis G

更新日期：2011-09-28 00:00:00

abstract：AIM:To investigate the prevalence and clinical significance of "anti-HBc alone" in an unselected population of patients and employees of a university hospital in southern Germany. METHODS:All individuals with the pattern "anti-HBc alone" were registered over a time span of 82 mo. HBV-DNA was measured in serum and live...

journal_title：World journal of gastroenterology

authors： Knöll A,Hartmann A,Hamoshi H,Weislmaier K,Jilg W

更新日期：2006-02-28 00:00:00

abstract：AIM:To investigate the effect of APOBEC3G mediated antiviral activity against hepatitis B virus (HBV) in cell cultures and replication competent HBV vector-based mouse model. METHODS:The mammalian hepatoma cells Huh7 and HepG2 were cotransfected with various amounts of CMV-driven expression vector encoding APOBEC3G an...

journal_title：World journal of gastroenterology

authors： Lei YC,Hao YH,Zhang ZM,Tian YJ,Wang BJ,Yang Y,Zhao XP,Lu MJ,Gong FL,Yang DL

更新日期：2006-07-28 00:00:00

abstract：:Poorly differentiated endocrine carcinoma (PDEC) of the pancreas is a rare and aggressive tumor. First-line treatment is commonly a combination of etoposide and cisplatin, but there is no consensus regarding further treatment recommendations. In this report, we describe a case of pancreatic PDEC treated with gemcitabi...

journal_title：World journal of gastroenterology

authors： Nakazuru S,Yoshio T,Suemura S,Itoh M,Araki M,Yoshioka C,Ohta M,Sueyoshi Y,Ohta T,Hasegawa H,Morita K,Toyama T,Kuzushita N,Kodama Y,Mano M,Mita E

更新日期：2010-08-14 00:00:00

abstract：:Our goal is to provide a detailed review of veno-occlusive disease (VOD), Budd-Chiari syndrome (BCS), and congestive hepatopathy (CH), all of which results in hepatic venous outflow obstruction. This is the first article in which all three syndromes have been reviewed, enabling the reader to compare the characteristic...

journal_title：World journal of gastroenterology

authors： Bayraktar UD,Seren S,Bayraktar Y

更新日期：2007-04-07 00:00:00