Associations between oxidative parameters in pregnancy and birth anthropometry in a cohort of women and children in rural Bangladesh: the MINIMat-cohort.

abstract：:We have determined the effects of chronic vitamin C intake on neutrophil and lymphocyte antioxidant defences during the acute phase immune response induced by intense exercise. Blood samples were taken from 16 voluntary athletes in basal conditions, both immediately after and 1 h after a duathlon competition. Sportsme...

journal_title：Free radical research

authors： Tauler P,Aguiló A,Gimeno I,Noguera A,Agustí A,Tur JA,Pons A

更新日期：2003-09-01 00:00:00

abstract：:Effects of 12 wk exercise training on oxidative stress were examined in elderly humans. We measured oxidative stress during a 45 min cycling test by using antipyrine hydroxylation products. Antipyrine breakdown is independent of blood flow to the liver, which is important during exercise. Furthermore, antipyrine react...

journal_title：Free radical research

authors： Meijer EP,Coolen SA,Bast A,Westerterp KR

更新日期：2001-10-01 00:00:00

abstract：:Melatonin is an endogenous indolamine, classically known as a light/dark regulator. Besides classical functions, melatonin has also showed to have a wide range of antitumoral effects in numerous cancer experimental models. However, no definite mechanism has been described to explain the whole range of antineoplasic ef...

journal_title：Free radical research

authors： Sánchez-Sánchez AM,Martín V,García-Santos G,Rodríguez-Blanco J,Casado-Zapico S,Suarez-Garnacho S,Antolín I,Rodriguez C

更新日期：2011-11-01 00:00:00

abstract：:γ-Tocopherol (γ-T) scavenges reactive nitrogen species (RNS) to form 5-NO2-γ-T (NGT). However, α-T supplementation decreases circulating γ-T, which could limit its RNS scavenging activities. We hypothesized that α-T supplementation would mitigate NGT accumulation by impairing γ-T status. Healthy smokers (21 ± 1 y, n =...

journal_title：Free radical research

authors： Pei R,Mah E,Leonard SW,Traber MG,Bruno RS

更新日期：2015-01-01 00:00:00

abstract：:The response of HeLa cells to subcellular spatially localized two-photon irradiation of a singlet oxygen photosensitizer (protoporphyrin IX, PpIX) using a focused laser was assessed. Upon irradiation under these conditions, a localized population of PpIX excited states can be produced with meaningful intracellular spa...

journal_title：Free radical research

authors： Gollmer A,Besostri F,Breitenbach T,Ogilby PR

更新日期：2013-09-01 00:00:00

abstract：:The toxic effect of copper was evaluated in sunflower plants by means of root elongation, lipid peroxidation and antioxidative enzyme activities. Plants were grown under controlled environmental conditions in hydroponic culture for two weeks and exposed to different copper concentrations for an additional week. Determ...

journal_title：Free radical research

authors： García A,Baquedano FJ,Navarro P,Castillo FJ

更新日期：1999-12-01 00:00:00

abstract：:Reactive oxygen species (ROS) released from polymorphonuclear leukocytes and macrophages could cause DNA damage, but also induce cell death. Therefore inhibition of cell death must be an important issue for accumulation of genetic changes in lymphoid cells in inflammatory foci. Scavengers in the post culture medium of...

journal_title：Free radical research

authors： Miwa H,Fujii J,Kanno H,Taniguchi N,Aozasa K

更新日期：2000-07-01 00:00:00

abstract：:A zinc(II) phthalocyanine compound, tetra-alpha-(2,2,4-tirmethyl-3-pentoxy) Phthalocyanine Zinc (ZnPc(OR)(4)) was synthesized in this paper and this zinc (II) phthalocyanine compound was used as the photosensitizer in the photoinduced chemiluminescence (PCL) of lucigenin in N,N-dimethylformamide (DMF). The photoexcite...

journal_title：Free radical research

authors： Wang J,Jiang Z,Huang L,Huang J,Chen G

更新日期：2008-02-01 00:00:00

abstract：:Manganese superoxide dismutase (MnSOD) levels have been found to be low in human pancreatic cancer [Pancreas 26, (2003), 23] and human pancreatic cancer cell lines [Cancer Res. 63, (2003), 1297] when compared to normal human pancreas. We hypothesized that stable overexpression of pancreatic cancer cells with MnSOD cDN...

journal_title：Free radical research

authors： Ough M,Lewis A,Zhang Y,Hinkhouse MM,Ritchie JM,Oberley LW,Cullen JJ

更新日期：2004-11-01 00:00:00

abstract：:Carotenoids scavenge simple lipid-like alkylperoxyl radicals. However, the rate constant is too low to be determined directly and the mechanism is likewise not known with certainty [Mortensen, A. and Skibsted, L.H. (1998) FEBS Lett. 426, 392-396]. It is demonstrated that carotenoids react with peroxyl radicals only sl...

journal_title：Free radical research

authors： Mortensen A

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Measurement of urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) has recently become more popular as a means of assessing oxidative stress in the human body. The aim of this study is to compare the levels of urine 8-OHdG in patients with type 2 diabetes with and without nephropathy and to evaluate its role as a b...

journal_title：Free radical research

authors： Serdar M,Sertoglu E,Uyanik M,Tapan S,Akin K,Bilgi C,Kurt I

更新日期：2012-10-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a lung disease caused by an inflammatory response to various inhaled toxins, especially cigarette smoke. Reactive oxygen species (ROS) and epigenetic abnormality are intimately related to the pathology of COPD, and the overproduction of ROS results in a decrease of histo...

journal_title：Free radical research

authors： Chikuma K,Arima K,Asaba Y,Kubota R,Asayama S,Sato K,Kawakami H

更新日期：2019-12-06 00:00:00

abstract：:Glutathione plays a central role in the maintenance of cellular antioxidant defense. The alterations in the glutathione and associated recyclic enzymes caused by both exercise training and ethanol are well documented; however, their interactive effects with age are not well understood. Therefore, the influence of agei...

journal_title：Free radical research

authors： Kakarla P,Kesireddy S,Christiaan L

更新日期：2008-05-01 00:00:00

abstract：:Anxiety disorders are the most common mental illness in the USA affecting 18% of the population. The cause(s) of anxiety disorders is/are not completely clear, and research in the neurobiology of anxiety at the molecular level is still rather limited. Although mounting clinical and preclinical evidence now indicates t...

journal_title：Free radical research

authors： Fedoce ADG,Ferreira F,Bota RG,Bonet-Costa V,Sun PY,Davies KJA

更新日期：2018-07-01 00:00:00

abstract：:After minimal sample preparation, two different HPLC methodologies, one based on a single gradient reversed-phase HPLC step, the other on multiple HPLC runs each optimised for specific components, were used to investigate the composition of flavonoids and phenolic acids in apple and tomato juices. The principal compon...

journal_title：Free radical research

authors： Bremner PD,Blacklock CJ,Paganga G,Mullen W,Rice-Evans CA,Crozier A

更新日期：2000-06-01 00:00:00

abstract：:Enhanced oxidative stress partly resulting from an over-production of superoxide anion (O(2)(•-)) represents a novel and particular risk factor in chronic kidney disease (CKD) patients. This study was therefore designed to evaluate O(2)(•-) determinants in this population. O(2)(•-) production was evaluated using chemi...

journal_title：Free radical research

authors： Morena M,Patrier L,Jaussent I,Bargnoux AS,Dupuy AM,Badiou S,Leray-Moragues H,Klouche K,Canaud B,Cristol JP

更新日期：2011-06-01 00:00:00

abstract：:Epidemiology studies have shown that consumption of fruits and vegetables is associated with the prevention of chronic diseases such as cancer and cardiovascular disease. Induction of cellular phase II detoxifying enzymes is associated with cancer preventive potential. Phenolsulfotransferases (PSTs) are traditionally ...

journal_title：Free radical research

authors： Yeh CT,Yen GC

更新日期：2005-08-01 00:00:00

abstract：:We describe an altered membrane band 3 protein-mediated anion transport in erythrocytes exposed to peroxynitrite, and relate the loss of anion transport to cell damage and to band 3 oxidative modifications. We found that peroxynitrite down-regulate anion transport in a dose dependent relation (100-300 micromoles/l). H...

journal_title：Free radical research

authors： Celedón G,González G,Pino J,Lissi EA

更新日期：2007-03-01 00:00:00

abstract：:We investigated hepatoprotective activity and antioxidant effect of the 2,5-dihydroxy-4,3'-di(beta-D-glucopyranosyloxy)-trans-stilbene that purified from Morus bombycis Koidzumi roots against CCl4-induced liver damage in rats. The 2,5-dihydroxy-4,3'-di(beta-D-glucopyranosyloxy)-trans-stilbene displayed dose-dependent ...

journal_title：Free radical research

authors： Jin YS,Lee MJ,Han W,Heo SI,Sohn SI,Wang MH

更新日期：2006-09-01 00:00:00

abstract：:The markers 3-nitrotyrosine and 3-chlorotyrosine are measured as surrogates for reactive nitrogen species and hypochlorous acid respectively, which are both elevated in inflamed human tissues. Previous studies reported a loss of 3-nitrotyrosine when exposed to hypochlorous acid, suggesting that observations of 3-nitro...

journal_title：Free radical research

authors： Curtis MP,Neidigh JW

更新日期：2014-11-01 00:00:00

abstract：:In the present study we isolated proteasome complexes from control, mild cognitive impairment (MCI), and Alzheimer's disease (AD) subjects. No significant difference in the amount of proteasomes was detected across the different groups, although impairments in chymotrypsin-like proteasome activity was observed in AD s...

journal_title：Free radical research

authors： Cecarini V,Ding Q,Keller JN

更新日期：2007-06-01 00:00:00

abstract：:Rabbits were fed a diet containing 1% cholesterol for 8 weeks and the levels of iron and oxidized lipids in liver analysed using atomic absorption spectroscopy and gas chromatography-mass spectrometry. A non-significant trend to an increase in iron level, but significant increases in the lipid peroxidation products, F...

journal_title：Free radical research

authors： Ong WY,Jenner AM,Pan N,Ong CN,Halliwell B

更新日期：2009-03-01 00:00:00

abstract：:The purpose of this study was to investigate the absorption and metabolism of hydroxycinnamates from artichoke extract by determining the urinary excretion of the conjugates. Ten healthy, non smoking volunteers (5 female, 5 male) were given three capsules containing artichoke extract every 4 h (0, 4, 8 h) following tw...

journal_title：Free radical research

authors： Rechner AR,Pannala AS,Rice-Evans CA

更新日期：2001-08-01 00:00:00

abstract：:Copper Fenton systems (Cu(II)/H2O2 and Cu(II)/Asc) inactivated the lipoamide reductase and enhanced the diaphorase activity of pig-heart lipoamide dehydrogenase (LADH). Cupric ions alone were less effective. As a result of Cu(II)/H2O2 treatment, the number of titrated thiols in LADH decreased from 6 to 1 per subunit. ...

journal_title：Free radical research

authors： Gutierrez-Correa J,Stoppani AO

更新日期：1995-03-01 00:00:00

abstract：:Adriamycin (ADR) is a chemotherapeutic agent useful in treating various cancers. ADR is a quinone-containing anthracycline chemotherapeutic and is known to produce reactive oxygen species (ROS) in heart. Application of this drug can have serious side effects in various tissues, including brain, apart from the known ca...

journal_title：Free radical research

authors： Joshi G,Sultana R,Tangpong J,Cole MP,St Clair DK,Vore M,Estus S,Butterfield DA

更新日期：2005-11-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) induces expression of the proinflammatory and profibrotic cytokine monocyte chemoattractant protein-1 (MCP-1) in tubular epithelial cells (TECs) and thereby contributes to the tubular epithelial-mesenchymal transition (EMT), which in turn leads to the progression of tubulointerst...

journal_title：Free radical research

authors： Li A,Wang J,Zhu D,Zhang X,Pan R,Wang R

更新日期：2015-01-01 00:00:00

abstract：:The European Standards Committee on Oxidative DNA Damage (ESCODD) was set up in 1997 to resolve methodological problems and to reach agreement on the basal level of 8-oxo-2'-deoxyguanosine (8-oxodG) in biological samples. In the present ESCODD trial 6 samples of 8-oxodG-containing oligonucleotides with different ratio...

journal_title：Free radical research

authors： Riis B

更新日期：2002-06-01 00:00:00

abstract：:Creatol (CTL) is a product resulting from the reaction of creatinine (Cr) with the hydroxyl radical and is identified as a precursor of methylguanidine (MG), a uremic toxin. In this study, we investigated serum CTL levels together with those of Cr and MG in 66 patients who were on maintenance hemodialysis (HD). Prior ...

journal_title：Free radical research

authors： Tomida C,Aoyagi K,Nagase S,Gotoh M,Yamagata K,Takemura K,Koyama A

更新日期：2000-01-01 00:00:00

abstract：:An iodoacetamide azaadamantyl spin label was studied in fluid solution and in 9:1 trehalose:sucrose glass. In 9:1 toluene:CH2Cl2 solution at 293 K, the isotropic nitrogen hyperfine coupling is 19.2 G, T1 is 0.37 µs and T2 is 0.30-0.35 µs. Between about 80 and 150 K 1/Tm in 9:1 trehalose:sucrose is approximately indepe...

journal_title：Free radical research

authors： Eaton SS,Rajca A,Yang Z,Eaton GR

更新日期：2018-03-01 00:00:00

abstract：:Peroxiredoxin 1 (PRDX1) is an antioxidant enzyme that, when secreted, can act as a proinflammatory signal. Here we studied the regulation of intracellular PRDX1 by lipopolysaccharide (LPS) and interferon-gamma (IFN-γ) in the RAW 264.7 mouse macrophage cell line. While LPS or IFN-γ alone did not affect PRDX1 protein le...

journal_title：Free radical research

authors： Ingram S,Mengozzi M,Heikal L,Mullen L,Ghezzi P

更新日期：2019-08-01 00:00:00