Coexisting ankylosing spondylitis and rheumatoid arthritis: a case report with literature review.

Abstract:

:A 30-year-old female patient with coexisting ankylosing spondylitis and rheumatoid arthritis was diagnosed and treated. The human leukocyte antigen (HLA)-B27 is a predisposing factor of ankylosing spondylitis and HLA-DR4 is a predisposing factor of rheumatoid arthritis. This patient was HLA-B27 and HLA-DR4 positive, and ankylosing spondylitis manifested before rheumatoid arthritis. After disease modifying anti-rheumatic drugs successfully arrested ankylosing spondylitis activity the patient conceived and delivered a healthy baby. One year later, she developed peripheral polyarthritis and was diagnosed with rheumatoid arthritis. We hypothesized that pregnancy may be one of the environmental factors that can activate rheumatoid arthritis, and that disease modifying anti-rheumatic drugs play an important role in keeping the disease under control.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Guo YY,Yang LL,Cui HD,Zhao S,Zhang N

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

3430-2

issue

20

eissn

0366-6999

issn

2542-5641

journal_volume

124

pub_type

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