Exercise training in recently hospitalized heart failure patients enrolled in a disease management programme: design of the EJECTION-HF randomized controlled trial.

Abstract:

AIMS:The Exercise Joins Education: Combined Therapy to Improve Outcomes in Newly-discharged Heart Failure (EJECTION-HF) study will evaluate the impact of a supervised exercise training programme (ETP) on clinical outcomes in recently hospitalized heart failure patients attending a disease management programme (DMP). Methods This multisite, pragmatic randomized controlled trial enrols patients discharged from participating hospitals with clinical evidence of heart failure who are willing and able to participate in a DMP and considered clinically safe to exercise. Enrolment includes participants with impaired and preserved left ventricular systolic function. Baseline assessment and programme commencement occur within 6 weeks of hospital discharge. The control group DMP includes individualized education and follow-up from a multidisciplinary heart failure team; a weekly education programme for 12 weeks; self-management advice; and medical follow-up. Home exercise is recommended for all participants. In addition, intervention participants are offered 36 supervised, structured gym-based 1 h exercise sessions over 24 weeks. Sessions are tailored to exercise capacity and include aerobic, resistance, and balance exercises. Enrolment target is 350 participants. Primary outcome is 12-month mortality and readmissions. Secondary outcomes include blinded evaluation of depressive symptoms, sleep quality, cognition, and functional status (activities of daily living, 6 min walk distance, grip strength) at 3 and 6 months. A cost-utility analysis will be conducted. CONCLUSION:This study will enrol a representative group of hospitalized heart failure patients and measure a range of patient and health service outcomes to inform the design of post-hospital DMPs for heart failure. Enrolment will be completed in 2013. ACTRN12608000263392.

journal_name

Eur J Heart Fail

authors

Mudge AM,Denaro CP,Scott AC,Atherton JJ,Meyers DE,Marwick TH,Adsett JA,Mullins RW,Suna JM,Scuffham PA,O'Rourke PK

doi

10.1093/eurjhf/hfr139

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1370-5

issue

12

eissn

1388-9842

issn

1879-0844

pii

hfr139

journal_volume

13

pub_type

杂志文章,多中心研究,随机对照试验
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    pub_type: 临床试验,杂志文章,随机对照试验

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    pub_type: 杂志文章

    doi:10.1002/ejhf.1974

    authors: Rosenblum H,Masri A,Narotsky DL,Goldsmith J,Hamid N,Hahn RT,Kodali S,Vahl T,Nazif T,Khalique OK,Bokhari S,Soman P,Cavalcante JL,Maurer MS,Castaño A

    更新日期:2020-07-30 00:00:00

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    pub_type: 杂志文章

    doi:10.1002/ejhf.1984

    authors: Selvaraj S,Claggett BL,Pfeffer MA,Desai AS,Mc Causland FR,McGrath MM,Anand IS,van Veldhuisen DJ,Kober L,Janssens S,Cleland JGF,Pieske B,Rouleau JL,Zile MR,Shi VC,Lefkowitz MP,McMurray JJV,Solomon SD

    更新日期:2020-11-01 00:00:00

  • Short-term effects of sinus rhythm restoration in patients with lone atrial fibrillation: a hormonal study.

    abstract::It is well known that atrial fibrillation can lead to heart failure, and is attributed to rapid ventricular rate (tachycardia-induced cardiomyopathy). Some recent studies suggest the possible existence of an intrinsic left-ventricular factor related to atrial fibrillation, irrespective of other elements. In order to d...

    journal_title:European journal of heart failure

    pub_type: 杂志文章

    doi:10.1016/s1388-9842(02)00004-1

    authors: Jourdain P,Bellorini M,Funck F,Fulla Y,Guillard N,Loiret J,Thebault B,Sadeg N,Desnos M

    更新日期:2002-06-01 00:00:00