Abstract：
:The hypothesis is proposed that pre-biotic bacterial cell(s) and the first cells capable of growth/division did not require a cytoplasmic membrane. A gel-like microscopic structure less than a cubic micrometer may have had a dual role as both an ancient pre-cytoplasm and a boundary layer to the higher-entropy external environment. The gel pre-cytoplasm exposed to radiant energy, especially in the infrared (IR) region of the EM spectrum resulted in the production of an exclusion zone (EZ) with a charge differential (-100 to -200 mV) and boundary that may have been a possible location for the latter organization of the first cytoplasmic membrane. Pre-biotic cells and then-living cells may have used hydrogen as the universal energy source, and thermosynthesis in their bioenergetic processes. These components will be discussed as to how they are interconnected, and their hypothesized roles in the origin of life.
journal_name
Biochimiejournal_title
Biochimieauthors
Trevors JT,Pollack GHdoi
10.1016/j.biochi.2011.10.002subject
Has Abstractpub_date
2012-01-01 00:00:00pages
258-62issue
1eissn
0300-9084issn
1638-6183pii
S0300-9084(11)00381-6journal_volume
94pub_type
杂志文章相关文献
BIOCHIMIE文献大全abstract：:The kinetoplastid protozoan Leishmania encodes major surface glycoprotein GP63, a zinc metallo-peptidase (EC.3.4.24.36) expressed both in promastigote and amastigote life stages. In the present study, we explored for the first time the role of C-terminal domain (CTD) in proteinase activity by serial truncation of Leis...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2010.07.014
更新日期：2010-12-01 00:00:00
abstract：:Labeling of 21-kDa material was observed when bovine brain soluble fraction was incubated with [adenylate-32P]NAD+ in the presence of GTP. The 21-kDa substrate, slightly smaller than C3 substrate in size, was labeled even without C3 exoenzyme. GTP could be replaced by nucleoside triphosphates other than ATP while ATP ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(97)86150-0
更新日期：1997-07-01 00:00:00
abstract：:A discriminating system capable of recognizing the oxygenated sterols was investigated in human lymphocytes. After labelling entire cells with 25-hydroxy [3H] cholesterol (10 nM) the cytosol was ultracentrifuged on a linear sucrose density gradient. Bound 25-hydroxy [3H] cholesterol was located in a single peak with a...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(82)80437-9
更新日期：1982-05-01 00:00:00
abstract：:The genus Populus is an effective model in tree genetics. This genus includes dioecious species and, recently, whole genome resequencing of P. trichocarpa and P. balsamifera enabled the identification of sex-linked regions and sex-associated single nucleotide polymorphisms (SNPs). These results created new opportuniti...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2019.03.018
更新日期：2019-07-01 00:00:00
abstract：:Betaine aldehyde dehydrogenase from the human opportunistic pathogen Pseudomonas aeruginosa (PaBADH) catalyzes the irreversible, NAD(P)(+)-dependent oxidation of betaine aldehyde, producing glycine betaine, an osmoprotectant. PaBADH participates in the catabolism of choline and likely in the defense against the osmoti...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2010.09.022
更新日期：2011-02-01 00:00:00
abstract：:Sequence analysis of the Lutzomyia (Lu.) ayacuchensis salivary gland cDNA library identified a short peptide containing an RGD (Arg-Gly-Asp) sequence flanked by two cysteine residues in the C-terminal end as the most abundant transcript. In the present study, a recombinant protein of the RGD-containing peptide, design...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2015.02.011
更新日期：2015-05-01 00:00:00
abstract：:Hemorrhage is the most potent manifestation of envenomation by Vipera ammodytes ammodytes (V. a. ammodytes) venom in man. A detailed description of the venom components contributing to this effect is thus medically very important. We have characterized a novel component, termed here VaH3, as a potently hemorrhagic sna...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2013.01.003
更新日期：2013-06-01 00:00:00
abstract：:Autotaxin (ATX) is a secreted lysophospholipase D involved in synthesis of lysophosphatidic acid (LPA), a phospholipid growth factor acting via specific receptors (LPA1R to LPA6R) and involved in several pathologies including obesity. ATX is secreted by adipocytes and contributes to circulating LPA. ATX expression is ...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2013.04.010
更新日期：2014-01-01 00:00:00
abstract：:The cartilage tissue has a limited self-regenerative capacity. Tissue-engineering represents a promising trend for cartilage repair. The present study was aimed to develop a biomaterial formulation by combining fragments of chitosan hydrogel with isolated rabbit or human chondrocytes. We first reported the properties ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2006.03.002
更新日期：2006-05-01 00:00:00
abstract：:pH-Dependence of hydrolytic activity of trypsin has been studied in cationic reverse micellar system of cetyltrimethylammonium bromide (CTAB) in (50% v/v) chloroform/isooctane using a positively charged substrate N(alpha)-benzoyl-L-arginine ethyl ester (BAEE). The pH of the medium was varied from 4.0 to 8.5 with addit...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(99)80007-8
更新日期：1998-12-01 00:00:00
abstract：:The imprinted gene Grb10 influences fetal growth, adult behavior and tumor formation. Investigating this gene often involves consecutive passaging of cells in vitro. We analyzed changes in Grb10 DNA methylation and histone modifications in serially passaged adult mouse tail-tip fibroblast cells with bisulfite genomic ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2012.08.009
更新日期：2012-12-01 00:00:00
abstract：:The effect of curing agents (salt, nitrate, ascorbic acid and glucose) and processing parameters (pH, water activity and drying and cooking temperatures) on pork muscle cathepsins B, D, H and L as well as leucyl, arginyl and tyrosyl hydrolysing activities is reported. Salt (60 g/l) showed a powerful inhibitory effect,...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(92)90128-2
更新日期：1992-03-01 00:00:00
abstract：:The mechanism of action on rabbit red cells of Treponema hyodysenteriae hemolysin was studied using volume analysis and release of hemoglobin. While fixation of the hemolysin on the erythrocytes is temperature independent, it appears that hemolysis is temperature dependent. The kinetics of hemolysis proceed according ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(80)80134-9
更新日期：1980-01-01 00:00:00
abstract：:Adipose tissue is an endocrine organ that plays an essential role in regulating several metabolic functions through the secretion of biological mediators called "adipokines". Dysregulation of adipokines plays a crucial role in obesity-related diseases. Adiponectin (APN) is the most abundant adipokine accounting for th...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2012.06.030
更新日期：2012-10-01 00:00:00
abstract：:The gene for the ribosomal protein L5 from the archaebacterium Sulfolobus acidocaldarius has been isolated and sequenced. The gene codes for a basic protein of molecular weight 29 165 Da. This protein shows substantial similarity to the equivalent protein from other archaebacteria as well as from yeast, and considerab...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(91)90047-5
更新日期：1991-06-01 00:00:00
abstract：:Coenzymes are small organic molecules that supply a varied set of reactive groups to protein enzymes, thereby diversifying catalysis beyond the chemistries of amino acid sidechains. As RNA structures begin with a more limited chemical diversity than proteins, it seems likely that RNA enzymes would also use functional ...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/s0300-9084(02)01404-9
更新日期：2002-09-01 00:00:00
abstract：:A depletion in long-chain polyunsaturated omega3 fatty acids may affect fuel homeostasis. In such a perspective, the present study deals mainly with the in vitro fate of D-[U-(14)C]glucose in hemidiaphragms, stretched soleus and plantaris muscle pieces obtained from normal and omega3-depleted rats (second generation) ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2006.10.004
更新日期：2007-03-01 00:00:00
abstract：:The yeast Saccharomyces cerevisiae strain LB332 bearing a mutation in the ERG20 gene encoding farnesyl diphosphate synthase (FPPS) synthesizes significantly longer dolichols than the wild type strain FL100 (14-31 and 14-19 isoprene units, respectively). The measurement of the short chain prenyl alcohols excreted into ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(00)01155-x
更新日期：2000-08-01 00:00:00
abstract：:Isovaleryl-CoA dehydrogenase (IVD) catalyzes the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA and the transfer of electrons to the electron transfer flavoprotein (ETF). Recombinant human IVD purifies with bound CoA-persulfide. A modified purification protocol was developed to isolate IVD without bound CoA-pers...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2014.11.007
更新日期：2015-01-01 00:00:00
abstract：:Protein 3D structures support their biological functions. As the number of protein structures is negligible in regards to the number of available protein sequences, prediction methodologies relying only on protein sequences are essential tools. In this field, protein secondary structure prediction (PSSPs) is a mature ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2020.09.006
更新日期：2020-12-01 00:00:00
abstract：:We describe a method to compare two fluorescence anisotropy decay curves. After numerical deconvolution of both decays by a non a priori method [1], their difference, D, is considered. The variance is computed for each point of D. A confidence interval is defined which allows a decision to be made as to the significan...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(84)90117-2
更新日期：1984-09-01 00:00:00
abstract：:The ascomycete Cladosporium herbarum is a prominent fungal inducer of Type I allergy. The only major allergen identified so far is Cla h 8, a NADP-dependent mannitol dehydrogenase (MtDH). MtDH, a cytoplasmic protein of 28.5kDa, belongs to the Short chain Dehydrogenases/Reductases (SDR), acting as a NADP-dependent oxid...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2010.04.012
更新日期：2010-08-01 00:00:00
abstract：:Cell-to-cell movement of Poa semilatent virus (genus Hordeivirus) in infected plants is mediated by three viral 'triple gene block' (TGB) proteins. One of those termed TGBp3 is an integral membrane protein essential for intracellular transport of other TGB proteins and viral genomic RNA to plasmodesmata. TGBp3 targeti...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2011.01.002
更新日期：2011-04-01 00:00:00
abstract：:Coumarins are a group of natural compounds widely distributed in plants. Of late, coumarins and their derivatives have grabbed much attention from the pharmacological and pharmaceutical arena due to their broad range of therapeutical qualities. A coumarin derivative 4-methylesculetin (4-ME) has known to possess effect...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2013.02.014
更新日期：2013-06-01 00:00:00
abstract：:Experimental Lyme arthritis provides a mouse model for exploring the development of pathology following infection of C3H mice with Borrelia burgdorferi. Infected mice develop a reliable inflammatory arthritis of the ankle joint with severity that typically peaks around two to three weeks post-infection and then underg...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2017.06.010
更新日期：2017-10-01 00:00:00
abstract：:Cell walls of flocculent strains (0006) and non flocculent strains (0019) of Saccharomyces uvarum (Carlsbergensis), grown in different media and taken in both growth and stationary phases, were treated with water and with 2 per cent (W/V) potassium hydroxide. This treatment yielded four fractions (FI, FII, FIII and FR...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/s0300-9084(81)80055-7
更新日期：1981-07-01 00:00:00
abstract：:Hyper- (450 mOsm/l) and hypoosmotic exposure (150 mOsm/l) of Caco-2 cells, a human intestinal epithelial cell line, induced a twofold- and a fivefold increase in the production of IL-8, a constitutively expressed cytokine, respectively. This was observed both in the presence or in the absence of added proinflammatory ...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2004.07.009
更新日期：2004-08-01 00:00:00
abstract：:The poisonous bite by Hippasa partita, a funnel web spider from the Indian subcontinent has been demonstrated to give rise to severe dermo- and myonecrosis. In this work a hemorrhagic metalloprotease, Partitagin was purified from H. partita venom by successive chromatography on Sephadex G-100, DEAE Sephadex A-50 and B...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/j.biochi.2007.04.005
更新日期：2007-11-01 00:00:00
abstract：:The present review deals with the place of single chain oligonucleotide ligands (aptamers) in affinity chromatography applied to proteins. Aptamers are not the only affinity ligands available but they represent an emerging and highly promising route that advantageously competes with antibodies in immunopurification pr...
journal_title：Biochimie
pub_type： 杂志文章,评审
doi：10.1016/j.biochi.2017.10.008
更新日期：2018-02-01 00:00:00
abstract：:Peptides with hormonal or neuronal activity are derived by enzymatic processing from pro-hormones, which by themselves are biologically inert. Processing and other enzymatic conversions may occur step-wise, leading to the formation of a cascade of biologically active (or inactive) peptides. The neurokin in substance P...
journal_title：Biochimie
pub_type： 杂志文章
doi：10.1016/0300-9084(88)90159-9
更新日期：1988-01-01 00:00:00
