The structure of the gene for ribosomal protein L5 in the archaebacterium Sulfolobus acidocaldarius.

abstract：:Isolation and properties of B. subtilis ts 19 mutant, isolated as thermosensitive for sporulation, are described. At the non permissive temperature (42degreesC), the mutant cells are blocked at stage zero of sporulation and do not excrete extracellular enzymes such as serylprotease and esterase. At the permissive temp...

journal_title：Biochimie

authors： Millet J,Larribe M,Aubert JP

更新日期：1976-01-01 00:00:00

abstract：:We have purified, by a three step procedure, a yeast C-nitrosoreductase and studied its action on p-nitroso-N,N-dimethylaniline. Microcalorimetric measurements performed on the microcalorimeter LKB "batch", have been given the number of protons exchanged during the reaction : four protons are involved. Two are given b...

journal_title：Biochimie

authors： Huynh CH

更新日期：1975-01-01 00:00:00

abstract：:Cell cycle-related and expression elevated protein in tumor (CREPT) is emerging as a novel cancer-related gene that is dysregulated in many kinds of malignancies. However, the expression and biological role of CREPT in glioma remains unclear. In the present study, we aimed to explore the potential function and regulat...

journal_title：Biochimie

authors： Wei M,Cao Y,Jia D,Zhao H,Zhang L

更新日期：2019-07-01 00:00:00

abstract：:Datura stramonium contains a compound that impairs learning retention in mice. It has been purified to homogeneity and its structure has been established as that of a gamma-L-glutamyl-L-aspartate. The biological activity of this pseudodipeptide has been found to be identical with that of the corresponding synthetic on...

journal_title：Biochimie

authors： Schmitz-Bourgeois M,Amiri I,Reinbolt J,Boulanger Y,Ungerer A

更新日期：1988-09-01 00:00:00

abstract：:The misfolding of amyloid proteins is closely correlated with the pathogenesis of protein conformation-related diseases, such as Alzheimer's disease (AD), prion disease, and type 2 diabetes mellitus (T2DM). The deposition of human islet amyloid polypeptide (hIAPP) and amyloid-β (Aβ) protein is entangled in AD and diab...

journal_title：Biochimie

authors： Xu J,Zhao C,Huang X,Du W

更新日期：2020-07-01 00:00:00

abstract：:Human α(1)-acid glycoprotein (AGP) is a positive acute phase plasma protein containing two disulfide bridges. Structural studies have shown that under specific conditions AGP undergoes aggregation. In this study, we analysed the nature of AGP's aggregates formed under reducing and non-reducing conditions at pH 5.5 and...

journal_title：Biochimie

authors： Scirè A,Baldassarre M,Galeazzi R,Tanfani F

更新日期：2013-02-01 00:00:00

abstract：:We present here, a new method for coupling sulfhydryl groups (SH) to low-density lipoprotein (LDL) surface. This method uses homocysteine thiolactone (HCTL) which reacts with lysine residues in a very mild manner, and permits the selection of the number of SH bound per LDL. Under our experimental conditions (8 SH/LDL)...

journal_title：Biochimie

authors： Vidal M,Sainte-Marie J,Philippot J,Bienvenue A

更新日期：1986-05-01 00:00:00

abstract：:We have studied the kinetics of erythromycin inhibition of translation in growing bacteria. In order to simplify the interpretation of our data, we have used a mutant (envA), known to have an increased permeability to several antibiotics, including erythromycin. The data clearly show that an initial stage of translati...

journal_title：Biochimie

authors： Andersson S,Kurland CG

更新日期：1987-08-01 00:00:00

abstract：:Mitochondrial membranes are essential for the good functioning of the organelle. For instance, the inner mitochondrial membrane contains the oxidative phosphorylation system that permits ATP synthesis. Phospholipids environment and especially cardiolipin are crucial for the mitochondrial energy metabolism. Indeed, car...

journal_title：Biochimie

authors： Dumas JF,Peyta L,Couet C,Servais S

更新日期：2013-01-01 00:00:00

abstract：:New strains of basidiomycetes producing extracellular laccases (Trametes ochracea 92-78, and Trametes hirsuta 56) have been found by screening of isolates of Trametes fungi. The laccases from T. hirsuta 56 and T. ochracea 92-78 as well as two laccases from previously found and described strains of basidiomycetes, name...

journal_title：Biochimie

authors： Shleev SV,Morozova OV,Nikitina OV,Gorshina ES,Rusinova TV,Serezhenkov VA,Burbaev DS,Gazaryan IG,Yaropolov AI

更新日期：2004-09-01 00:00:00

abstract：:Three Plasmodium falciparum serine repeat antigen (SERA) protein peptides were studied by NMR and structure calculations being done in 70:30 water:trifluoroethanol solution. Peptide 22834 was shown to be immunogenic and protective against malaria in Aotus monkeys, whilst native peptide 6737 and its analogue 14096 did ...

journal_title：Biochimie

authors： Cubillos M,Alba MP,Bermúdez A,Trujillo M,Patarroyo ME

更新日期：2003-07-01 00:00:00

abstract：:Kex2 is a Ca2+-dependent serine protease from S. cerevisiae. Characterization of the substrate specificity of Kex2 is of particular interest because this protease serves as the prototype of a large family of eukaryotic subtilisin-related proprotein-processing proteases that cleave sites consisting of pairs or clusters...

journal_title：Biochimie

authors： Manfredi MA,Antunes AA,Jesus LO,Juliano MA,Juliano L,Judice WA

更新日期：2016-12-01 00:00:00

abstract：:The variable manifestation of phenotypes that occur in patients with neurofibromatosis type 1 (NF1) includes benign and malignant neurocutaneous tumors for which no adequate treatment exists. Cell-based screening of known bioactive compounds library identified the protein phosphatase 2A (PP2A) inhibitor Cantharidin an...

journal_title：Biochimie

authors： Semenova G,Stepanova DS,Deyev SM,Chernoff J

更新日期：2017-04-01 00:00:00

abstract：:The amino acid sequence of rat thymus histone obtained in highly purified form by preparative electrophoresis, was determined. This sequence is identical to the sequence of calf thymus histone H2B. The in vitro phosphorylation of the rat histone with a cyclic AMP-dependent protein kinase isolated from rat pancreas led...

journal_title：Biochimie

authors： Martinage A,Mangeat P,Sautière P,Marchis-Mouren G,Biserte G

更新日期：1979-01-01 00:00:00

abstract：:We isolated and purified the main lipids of the rat sciatic nerve. After methanolysis, fatty acids were isolated and purified by thin layer chromatography, and studied by gas chromatography. C 16 and C 18 fatty acids are the most abundant. Among the long-chain fatty acids, arachidonic acid (20:4) is present in some li...

journal_title：Biochimie

authors： Klein F,Mandel P

更新日期：1978-01-01 00:00:00

abstract：:The cholesterol lowering drug lovastatin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, blocks DNA synthesis and proliferation of thyrotropin (TSH) primed FRTL-5 rat thyroid cells. The blockade can be completely prevented and/or reversed by mevalonate and largely prevented and/o...

journal_title：Biochimie

authors： Bifulco M,Laezza C,Aloj SM

更新日期：1999-04-01 00:00:00

abstract：:An immunological demonstration of alpha-fetoprotein (AFP) in uterine cytosol from immature rats is reported. The identity between serum AFP and the estrogen binding 4.5 S macromolecular complex of uterine cytosol was demonstrated by the use of a specific immunoadsorbent to AFP. Analysis of the sedimentation profile ...

journal_title：Biochimie

authors： Aussel C,Uriel J,Michel G,Baulieu EE

更新日期：1974-01-01 00:00:00

abstract：:A 3-D model of the tyrosylable tRNA-like domain of the genomic brome mosaic virus RNAs was built by computer modelling based on solution probing of the molecule with different chemical and enzymatic reagents. This model encompasses four major structural domains, including two peculiar substructures oriented perpendicu...

journal_title：Biochimie

authors： Felden B,Florentz C,Westhof E,Giegé R

更新日期：1993-01-01 00:00:00

abstract：:A novel approach to genetic sequence analysis is presented. This approach, based on compression of algorithms, has been launched simultaneously by Grumbach and Tahi, Milosavljevic and Rivals. To reduce the description of an object, a compression algorithm replaces some regularities in the description by special codes....

journal_title：Biochimie

authors： Rivals E,Dauchet M,Delahaye JP,Delgrange O

更新日期：1996-01-01 00:00:00

abstract：:The lipoprotein complex from human gallbladder bile was challenged with anti-IgA and anti-IgG antisera in order to determine whether the apolipoprotein complex isolated from the detergent-free form of bile lipoprotein contains IgA and IgG. The apolipoprotein complex indeed crossreacts with anti-IgA and anti-IgG. In ad...

journal_title：Biochimie

authors： Vigne JL,Nalbone G,Lafont H,Lairon D,Chabert C,Domingo N,Hauton JC

更新日期：1981-10-01 00:00:00

abstract：:Conformational changes induced by the binding of nickel to horseradish peroxidase C (HRPC) were studied by electronic absorption spectroscopy, fluorescence spectroscopy and circular dichroism spectroscopy. Incubation of HRPC with various concentrations of Ni(2+) for 5 minutes resulted in changes in the enzyme absorpti...

journal_title：Biochimie

authors： Tayefi-Nasrabadi H,Keyhani E,Keyhani J

更新日期：2006-09-01 00:00:00

abstract：:Flavodoxins are one domain alpha/beta electron transfer proteins that participate in photosynthetic reactions. All flavodoxins carry a molecule of flavin mononucleotide (FMN), non-covalently bound, that confers redox properties to the protein. There are two structurally distinct flavodoxins, short ones and long flavod...

journal_title：Biochimie

authors： Maldonado S,Lostao A,Irún MP,Férnandez-Recio J,Gustavo Genzor C,Begoña González E,Rubio JA,Luquita A,Daoudi F,Sancho J

更新日期：1998-10-01 00:00:00

abstract：:A variety of species of GPDH undergo acylation at two of the four active cystein sites per mole of tetrameric enzyme. This reaction requires tightly bound NAD+, a situation restricted to two of the four NAD sites per tetramer. S leads to N acyl transfer from cysteins to lysine in the diacyl enzyme yields an inactive e...

journal_title：Biochimie

authors： Malhotra OP,Bernhard SA,Seydoux F

更新日期：1981-02-01 00:00:00

abstract：:Snake venom phospholipases A2 (PLA2) share high sequence identities and a conserved structural scaffold, but show important functional differences. Only a few PLA2s have been purified and characterized from coral snake (Micrurus spp.) venoms, and their role in envenomation remains largely unknown. In this report, we d...

journal_title：Biochimie

authors： Rey-Suárez P,Núñez V,Saldarriaga-Córdoba M,Lomonte B

更新日期：2017-06-01 00:00:00

abstract：:The effect of curing agents (salt, nitrate, ascorbic acid and glucose) and processing parameters (pH, water activity and drying and cooking temperatures) on pork muscle cathepsins B, D, H and L as well as leucyl, arginyl and tyrosyl hydrolysing activities is reported. Salt (60 g/l) showed a powerful inhibitory effect,...

journal_title：Biochimie

authors： Toldrá F,Rico E,Flores J

更新日期：1992-03-01 00:00:00

abstract：:Five 4-arylcoumarins (1c-g) and twelve 3,4-dihydro-4-arylcoumarins (2a-l) were synthesized and tested for antioxidant activity, antitumor activity, toxicity and structure-activity relationships analysis. 4-Arylcoumarins and 3,4-dihydro-4-arylcoumarins that possess two hydroxyl groups in ortho position, such as 1d, 1f,...

journal_title：Biochimie

authors： Zhang K,Ding W,Sun J,Zhang B,Lu F,Lai R,Zou Y,Yedid G

更新日期：2014-12-01 00:00:00

abstract：:The published literature contains a number of examples of normally non-cytoplasmic proteins whose transport out of the cytoplasm is not completely abolished by drastic alterations to their routing signals (signal sequences, etc). Furthermore, there are numerous examples of cytoplasmic proteins that can be routed to an...

journal_title：Biochimie

authors： Pugsley AP

更新日期：1990-02-01 00:00:00

abstract：:NikR proteins are bacterial metallo-regulatory transcription factors that control the expression of the nickel uptake system and/or nickel containing enzymes such as urease, and are involved in the acid stress response. Here, a comparative study is reported on NikR from Helicobacter pylori (HpNikR) and Escherichia col...

journal_title：Biochimie

authors： Fauquant C,Diederix RE,Rodrigue A,Dian C,Kapp U,Terradot L,Mandrand-Berthelot MA,Michaud-Soret I

更新日期：2006-11-01 00:00:00

abstract：:Mammalian chymotrypsin-like serine proteases (SPs) are one of the best-studied family of enzymes with roles in a wide range of physiological processes, including digestion, blood coagulation, fibrinolysis and humoral immunity. Extracellular SPs can form cascades, in which one protease activates the zymogen of the next...

journal_title：Biochimie

authors： Veillard F,Troxler L,Reichhart JM

更新日期：2016-03-01 00:00:00

abstract：:Two-dimensional J-resolved and correlated 1H NMR spectra with complete water suppression have been obtained to further characterize a metabolic pattern for normal and pathological human plasma samples. 1H COSY spectra have been recorded on plasma from 12 patients with cancer in order to check for the possible presence...

journal_title：Biochimie

authors： Kriat M,Confort-Gouny S,Vion-Dury J,Viout P,Cozzone PJ

更新日期：1992-09-01 00:00:00