Laminar differences in gamma and alpha coherence in the ventral stream.

abstract：:The aggregation of the amyloid-β (Aβ) peptide is linked to the pathogenesis of Alzheimer's disease (AD). In particular, some point mutations within Aβ are associated with early-onset familial Alzheimer's disease. Here we set out to explore how the physical properties of the altered side chains, including their sizes a...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yang X,Meisl G,Frohm B,Thulin E,Knowles TPJ,Linse S

更新日期：2018-06-26 00:00:00

abstract：:It has recently been recognized that human serum contains a protein that specifically binds human growth hormone (hGH). This protein has the same restricted specificity for hGH as the membrane-bound GH receptor. To determine whether the GH-binding protein is a derivative of, or otherwise related to, the GH receptor, w...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Daughaday WH,Trivedi B

更新日期：1987-07-01 00:00:00

abstract：:The harvest of wildlife for human consumption is valued at several billion dollars annually and provides an essential source of meat for hundreds of millions of rural people living in poverty. This harvest is also considered among the greatest threats to biodiversity throughout Africa, Asia, and Latin America. Economi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Brashares JS,Golden CD,Weinbaum KZ,Barrett CB,Okello GV

更新日期：2011-08-23 00:00:00

abstract：:We advance a theory of resilience as it applies to the challenges of international development. The conceptualization we advance for development resilience focuses on the stochastic dynamics of individual and collective human well-being, especially on the avoidance of and escape from chronic poverty over time in the f...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Barrett CB,Constas MA

更新日期：2014-10-07 00:00:00

abstract：:The nucleotide-binding domain and leucine-rich repeats containing proteins (NLRs) serve as immune receptors in both plants and animals. Overaccumulation of NLRs often leads to autoimmune responses, suggesting that the levels of these immune receptors must be tightly controlled. However, the mechanism by which NLR prot...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cheng YT,Li Y,Huang S,Huang Y,Dong X,Zhang Y,Li X

更新日期：2011-08-30 00:00:00

abstract：:Major breakthroughs have recently been reported that can help overcome two inherent drawbacks of NMR: the lack of sensitivity and the limited memory of longitudinal magnetization. Dynamic nuclear polarization (DNP) couples nuclear spins to the large reservoir of electrons, thus making it possible to detect dilute endo...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vasos PR,Comment A,Sarkar R,Ahuja P,Jannin S,Ansermet JP,Konter JA,Hautle P,van den Brandt B,Bodenhausen G

更新日期：2009-11-03 00:00:00

abstract：:Tracheal antimicrobial peptide (TAP) is a member of the beta-defensin family of antibiotic peptides found in the tracheal mucosa of the cow. TAP gene expression in the bovine airway is inducible by lipopolysaccharide and inflammatory mediators, suggesting that it functions to protect the upper airway from infection. L...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yarus S,Rosen JM,Cole AM,Diamond G

更新日期：1996-11-26 00:00:00

abstract：:Sensory receptor neurons match their dynamic range to ecologically relevant stimulus intensities. How this tuning is achieved is poorly understood in most receptors. The roundworm Caenorhabditis elegans avoids 21% O2 and hypoxia and prefers intermediate O2 concentrations. We show how this O2 preference is sculpted by ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Oda S,Toyoshima Y,de Bono M

更新日期：2017-06-06 00:00:00

abstract：:Prenatal unilateral enucleation in mammals causes an extensive anatomical reorganization of visual pathways. The remaining eye innervates the entire extent of visual subcortical and cortical areas. Electrophysiological recordings have shown that the retino-geniculate connections are retinotopically organized and genic...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bisti S,Trimarchi C

更新日期：1993-12-01 00:00:00

abstract：:China has experienced rapid urbanization and dramatic economic growth since its reform process started in late 1978. In this article, we present evidence for a significant urbanization effect on climate based on analysis of impacts of land-use changes on surface temperature in southeast China, where rapid urbanization...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Zhou L,Dickinson RE,Tian Y,Fang J,Li Q,Kaufmann RK,Tucker CJ,Myneni RB

更新日期：2004-06-29 00:00:00

abstract：:Parasponia, a woody member of the elm family, is the only nonlegume genus whose members are known to form an effective nitrogen-fixing symbiosis with a Rhizobium species. The bacterial strain RP501 is a slow-growing strain of Rhizobium isolated from Parasponia nodules. Strain RP501 also nodulates the legumes siratro (...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Marvel DJ,Kuldau G,Hirsch A,Richards E,Torrey JG,Ausubel FM

更新日期：1985-09-01 00:00:00

abstract：:The anti-hapten responses to the dinitrophenyl (Dnp) conjugate of the random linear terpolymers poly(L-Glu,LLys,LPhe), GLphi, or poly(LGlu,LLys,LAla), GLA, are of highly restricted heterogeneity. Thus, individual mice of most responder strains express an average of two to four anti-Dnp clones to Dnp-GLphi or Dnp-GLA, ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kipps TJ,Benacerraf B,Dorf ME

更新日期：1978-06-01 00:00:00

abstract：:RNA interference (RNAi) is being used to develop methods to control pests and disease vectors. RNAi is robust and systemic in coleopteran insects but is quite variable in other insects. The determinants of efficient RNAi in coleopterans, as well as its potential mechanisms of resistance, are not known. RNAi screen ide...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yoon JS,Mogilicherla K,Gurusamy D,Chen X,Chereddy SCRR,Palli SR

更新日期：2018-08-14 00:00:00

abstract：:Dual-color fluorescence cross-correlation spectroscopy (dual-color FCS) has previously been shown to be a suitable tool not only for binding but also for catalytic rate studies. In this work, its application as a rapid method for high-throughput screening (HTS) and evolutionary biotechnology is described. This applica...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Koltermann A,Kettling U,Bieschke J,Winkler T,Eigen M

更新日期：1998-02-17 00:00:00

abstract：:Prostate cancer is a leading cause of cancer death in men over 50 years of age, and there is a characteristic marked decrease in Zn content in the malignant prostate cells. The cause and consequences of this loss have thus far been unknown. We found that in middle-aged rats a Zn-deficient diet reduces prostatic Zn lev...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Fong LY,Jing R,Smalley KJ,Wang ZX,Taccioli C,Fan S,Chen H,Alder H,Huebner K,Farber JL,Fiehn O,Croce CM

更新日期：2018-11-20 00:00:00

abstract：:Despite immense variability across languages, people can learn to understand any human language, spoken or signed. What neural mechanisms allow people to comprehend language across sensory modalities? When people listen to speech, electrophysiological oscillations in auditory cortex entrain to slow ([Formula: see text...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Brookshire G,Lu J,Nusbaum HC,Goldin-Meadow S,Casasanto D

更新日期：2017-06-13 00:00:00

abstract：:The protein CopC from Pseudomonas syringae has been found capable of binding copper(I) and copper(II) at two different sites, occupied either one at a time or simultaneously. The protein, consisting of 102 amino acids, is known to bind copper(II) in a position that is now found consistent with a coordination arrangeme...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Arnesano F,Banci L,Bertini I,Mangani S,Thompsett AR

更新日期：2003-04-01 00:00:00

abstract：:The fractionation of cells of a parsley suspension culture [Petroselinum crispum (Mill.) A. Hill] by protoplasting and subsequent removal of the vacuoles led to physiologically intact evacuolated protoplasts retaining light inducibility of chalcone synthase expression. Lysis of the evacuolated protoplasts permitted th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Harter K,Frohnmeyer H,Kircher S,Kunkel T,Mühlbauer S,Schäfer E

更新日期：1994-05-24 00:00:00

abstract：:Sleep is recognized as a physiological state associated with learning, with studies showing that knowledge acquisition improves with naps. Little work has examined sleep-dependent learning in people with developmental disorders, for whom sleep quality is often impaired. We examined the effect of natural, in-home naps ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Spanò G,Gómez RL,Demara BI,Alt M,Cowen SL,Edgin JO

更新日期：2018-11-13 00:00:00

abstract：:We introduce a family of fast ordered upwind methods for approximating solutions to a wide class of static Hamilton-Jacobi equations with Dirichlet boundary conditions. Standard techniques often rely on iteration to converge to the solution of a discretized version of the partial differential equation. Our fast method...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Sethian JA,Vladimirsky A

更新日期：2001-09-25 00:00:00

abstract：:Emerging evidence suggests that tissue plasminogen activator (tPA), currently the only FDA-approved medication for ischemic stroke, exerts important biological actions on the CNS besides its well-known thrombolytic effect. In this study, we investigated the role of tPA on primary neurons in culture and on brain recove...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pu H,Shi Y,Zhang L,Lu Z,Ye Q,Leak RK,Xu F,Ma S,Mu H,Wei Z,Xu N,Xia Y,Hu X,Hitchens TK,Bennett MVL,Chen J

更新日期：2019-04-30 00:00:00

abstract：:X-ray absorption spectra near the Kalpha edge have been measured in various iron group compounds using the intense synchrotron radiation at the Stanford Synchrotron Research Project. In the cubic compounds KMF3 where M = Mn+2, Fe+2, Co+2, Ni+2, and Zn+2, well resolved lines were observed and assigned to the 1s leads t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Shulman GR,Yafet Y,Eisenberger P,Blumberg WE

更新日期：1976-05-01 00:00:00

abstract：:Since the demonstration that the sequence of a protein encodes its structure, the prediction of structure from sequence remains an outstanding problem that impacts numerous scientific disciplines, including many genome projects. By iteratively fixing secondary structure assignments of residues during Monte Carlo simul...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： DeBartolo J,Colubri A,Jha AK,Fitzgerald JE,Freed KF,Sosnick TR

更新日期：2009-03-10 00:00:00

abstract：:The H2O2-requiring ligninase of the basidiomycete Phanerochaete chrysosporium oxidatively cleaves both lignin and lignin model compounds between C alpha and C beta (C-1 and C-2) of their aliphatic side chains. Previous work has demonstrated a reaction mechanism by which ligninase oxidizes aromatic substrates to their ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hammel KE,Kalyanaraman B,Kirk TK

更新日期：1986-06-01 00:00:00

abstract：:Climate models show that particles formed by nucleation can affect cloud cover and, therefore, the earth's radiation budget. Measurements worldwide show that nucleation rates in the atmospheric boundary layer are positively correlated with concentrations of sulfuric acid vapor. However, current nucleation theories do ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chen M,Titcombe M,Jiang J,Jen C,Kuang C,Fischer ML,Eisele FL,Siepmann JI,Hanson DR,Zhao J,McMurry PH

更新日期：2012-11-13 00:00:00

abstract：:Tumor hypoxia reduces the effectiveness of radiation therapy by limiting the biologically effective dose. An acute increase in tumor oxygenation before radiation treatment should therefore significantly improve the tumor cell kill after radiation. Efforts to increase oxygen delivery to the tumor have not shown positiv...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Benej M,Hong X,Vibhute S,Scott S,Wu J,Graves E,Le QT,Koong AC,Giaccia AJ,Yu B,Chen CS,Papandreou I,Denko NC

更新日期：2018-10-16 00:00:00

abstract：:Low phosphate (Pi) availability is one of the major constraints for plant productivity in natural and agricultural ecosystems. Plants have evolved a myriad of developmental and biochemical mechanisms to increase internal Pi uptake and utilization efficiency. One important biochemical pathway leading to an increase in ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Cruz-Ramírez A,Oropeza-Aburto A,Razo-Hernández F,Ramírez-Chávez E,Herrera-Estrella L

更新日期：2006-04-25 00:00:00

abstract：:The matrix 2 (M2) protein from influenza A virus is a proton channel that uses His37 as a selectivity filter. Here we report high-resolution (1.10 Å) cryogenic crystallographic structures of the transmembrane domain of M2 at low and high pH. These structures reveal that waters within the pore form hydrogen-bonded netw...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Thomaston JL,Alfonso-Prieto M,Woldeyes RA,Fraser JS,Klein ML,Fiorin G,DeGrado WF

更新日期：2015-11-17 00:00:00

abstract：:An RNA-directed DNA polymerase was isolated from the peripheral blood leukocytes of a patient with acute myelomonocytic leukemia by successive purification of a particulate cytoplasmic fraction with endogenous, ribonuclease-sensitive DNA polymerase activity. Like RNA-directed DNA polymerase from mammalian type-C virus...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gallagher RE,Todaro GJ,Smith RG,Livingston DM,Gallo RC

更新日期：1974-04-01 00:00:00

abstract：:In RBL-2H3 rat tumor mast cells, cross-linking the high-affinity IgE receptor Fc epsilon RI causes tyrosine phosphorylation of multiple proteins. These phosphoproteins include phospholipase C gamma 1, the beta and gamma subunits of the Fc epsilon RI, the Src family protein-tyrosine kinase Lyn, and a 72-kDa protein tha...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hutchcroft JE,Geahlen RL,Deanin GG,Oliver JM

更新日期：1992-10-01 00:00:00