当前位置： SCI文献检索 > PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA期刊下所有文献 > Visual cortex entrains to sign language.

Visual cortex entrains to sign language.

Abstract：

:Despite immense variability across languages, people can learn to understand any human language, spoken or signed. What neural mechanisms allow people to comprehend language across sensory modalities? When people listen to speech, electrophysiological oscillations in auditory cortex entrain to slow ([Formula: see text]8 Hz) fluctuations in the acoustic envelope. Entrainment to the speech envelope may reflect mechanisms specialized for auditory perception. Alternatively, flexible entrainment may be a general-purpose cortical mechanism that optimizes sensitivity to rhythmic information regardless of modality. Here, we test these proposals by examining cortical coherence to visual information in sign language. First, we develop a metric to quantify visual change over time. We find quasiperiodic fluctuations in sign language, characterized by lower frequencies than fluctuations in speech. Next, we test for entrainment of neural oscillations to visual change in sign language, using electroencephalography (EEG) in fluent speakers of American Sign Language (ASL) as they watch videos in ASL. We find significant cortical entrainment to visual oscillations in sign language <5 Hz, peaking at [Formula: see text]1 Hz. Coherence to sign is strongest over occipital and parietal cortex, in contrast to speech, where coherence is strongest over the auditory cortex. Nonsigners also show coherence to sign language, but entrainment at frontal sites is reduced relative to fluent signers. These results demonstrate that flexible cortical entrainment to language does not depend on neural processes that are specific to auditory speech perception. Low-frequency oscillatory entrainment may reflect a general cortical mechanism that maximizes sensitivity to informational peaks in time-varying signals.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Brookshire G,Lu J,Nusbaum HC,Goldin-Meadow S,Casasanto D

doi

10.1073/pnas.1620350114

subject

Has Abstract

pub_date

2017-06-13 00:00:00

pages

6352-6357

issue

24

eissn

0027-8424

issn

1091-6490

pii

1620350114

journal_volume

114

pub_type

杂志文章

相关文献

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA文献大全
  • MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.

    abstract：:The MLL (mixed-lineage leukemia) gene is involved in many chromosomal translocations associated with acute myeloid and lymphoid leukemia. We previously identified a transcriptional repression domain in MLL, which contains a region with homology to DNA methyltransferase. In chromosomal translocations, the MLL repressio...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1436338100

    authors： Xia ZB,Anderson M,Diaz MO,Zeleznik-Le NJ

    更新日期：2003-07-08 00:00:00

  • Discrete spiral modes in disk galaxies: Some numerical examples based on density wave theory.

    abstract：:Discrete growing spiral modes are calculated, on the basis of principles of stellar dynamics, according to the recently developed asymptotic theory of density waves for spiral structure in galaxies. From the growth rates obtained, it appears likely that several spiral modes coexist in a given disk galaxy. General prop...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.74.11.4726

    authors： Bertin G,Lau YY,Lin CC,Mark JW,Sugiyama L

    更新日期：1977-11-01 00:00:00

  • cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.

    abstract：:A human peripheral T-cell cDNA library was screened with two labeled synthetic oligonucleotides encoding regions of a human placenta protein-tyrosine-phosphatase (protein-tyrosine-phosphate phosphohydrolase, EC 3.1.3.48). One positive clone was isolated and the nucleotide sequence was determined. It contained 1305 bas...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.86.14.5257

    authors： Cool DE,Tonks NK,Charbonneau H,Walsh KA,Fischer EH,Krebs EG

    更新日期：1989-07-01 00:00:00

  • Ca2+-independent and Ca2+/GTP-binding protein-controlled exocytosis in a plant cell.

    abstract：:Exocytosis allows the release of secretory products and the delivery of new membrane material to the plasma membrane. So far, little is known about the underlying molecular mechanism and its control in plant cells. We have used the whole-cell patch-clamp technique to monitor changes in membrane capacitance to study ex...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.94.12.6565

    authors： Homann U,Tester M

    更新日期：1997-06-10 00:00:00

  • The derivation of ecological relationships from physical and chemical principles.

    abstract：:Organic reaction networks are formalized by representing chemical species as points in a space and representing reactions by connectivity rules. Using the generalized network, the behavior of the system is investigated under conditions of electronically exciting input and output to a thermal reservoir. Under steady-st...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.71.6.2335

    authors： Morowitz HJ

    更新日期：1974-06-01 00:00:00

  • Double-core-hole spectroscopy for chemical analysis with an intense X-ray femtosecond laser.

    abstract：:Theory predicts that double-core-hole (DCH) spectroscopy can provide a new powerful means of differentiating between similar chemical systems with a sensitivity not hitherto possible. Although DCH ionization on a single site in molecules was recently measured with double- and single-photon absorption, double-core hole...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1111380108

    authors： Berrah N,Fang L,Murphy B,Osipov T,Ueda K,Kukk E,Feifel R,van der Meulen P,Salen P,Schmidt HT,Thomas RD,Larsson M,Richter R,Prince KC,Bozek JD,Bostedt C,Wada S,Piancastelli MN,Tashiro M,Ehara M

    更新日期：2011-10-11 00:00:00

  • Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer.

    abstract：:This article extends our previous quantitative analysis of the relationship between the dynamics of the primary structure of DNA and mutagenesis associated with single-strand lesions to an analysis of the production and processing of endogenous double-strand breaks (EDSBs) and to their implications for oncogenesis. We...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.2135498100

    authors： Vilenchik MM,Knudson AG

    更新日期：2003-10-28 00:00:00

  • Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.

    abstract：:Complementary DNA (cDNA) clones encoding the adult human liver flavin-containing monooxygenase (FMO; dimethylaniline N-oxidase, EC 1.14.13.8) were isolated from lambda gt10 and lambda gt11 libraries. The cDNA libraries were screened with three synthetic 36-mer oligonucleotide probes derived from the nucleic acid seque...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.89.5.1685

    authors： Lomri N,Gu Q,Cashman JR

    更新日期：1992-03-01 00:00:00

  • Alignment of a 1.2-Mb chromosomal region from three strains of Rhodobacter capsulatus reveals a significantly mosaic structure.

    abstract：:High-resolution physical maps of the genomes of three Rhodobacter capsulatus strains, derived from ordered cosmid libraries, were aligned. The 1.2-Mb segment of the SB1003 genome studied here is adjacent to a 1-Mb region analyzed previously [Fonstein, M., Nikolskaya, T. & Haselkorn, H. (1995) J. Bacteriol. 177, 2368-2...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.92.23.10609

    authors： Nikolskaya T,Fonstein M,Haselkorn R

    更新日期：1995-11-07 00:00:00

  • LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.

    abstract：:TAL1 is a critical transcription factor required for hematopoiesis. However, perturbation of its activity often leads to T cell leukemia. Whether and how its transcriptional activities are regulated during hematopoiesis remains to be addressed. Here, we show that TAL1 is associated with histone demethylase complexes c...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0900437106

    authors： Hu X,Li X,Valverde K,Fu X,Noguchi C,Qiu Y,Huang S

    更新日期：2009-06-23 00:00:00

  • Murine hematopoietic reconstitution after tagging and selection of retrovirally transduced bone marrow cells.

    abstract：:A major problem facing the effective treatment of patients with cancer is how to get the specific antitumor agent into every tumor cell. In this report we describe the use of a strategy that, by using retroviral vectors encoding a truncated human CD5 cDNA, allows the selection of only the infected cells, and we show t...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.94.24.13239

    authors： García-Hernández B,Castellanos A,López A,Orfao A,Sánchez-García I

    更新日期：1997-11-25 00:00:00

  • Transcription program of the chloroplast genome of Euglena gracilis during chloroplast development.

    abstract：:RNA transcription in Euglena gracilis chloroplasts has been characterized by hybridization of RNA from cells at different stages of chloroplast development to (3)H-labeled chloroplast DNA restriction endonuclease fragments. Chloroplast DNA was digested into five fragments of 53,000, 35,000, 25,000, 10,000, and 6900 ba...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.76.5.2258

    authors： Chelm BK,Hallick RB,Gray PW

    更新日期：1979-05-01 00:00:00

  • Complex role of NK cells in regulation of oncolytic virus-bortezomib therapy.

    abstract：:In the present work, we investigated the role of natural killer (NK) cells in combination therapy with oncolytic virus (OV) and bortezomib, a proteasome inhibitor. NK cells display rapid and potent immunity to metastatic and hematological cancers, and they overcome immunosuppressive effects of tumor microenvironment. ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1715295115

    authors： Kim Y,Yoo JY,Lee TJ,Liu J,Yu J,Caligiuri MA,Kaur B,Friedman A

    更新日期：2018-05-08 00:00:00

  • Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein.

    abstract：:The human immunodeficiency virus 1 (HIV-1) long terminal repeat (LTR) sequences were inserted into adenovirus in place of the E1 region. The HIV-1 LTR contained in this recombinant adenovirus responds to trans-activation by tatIII in a HeLa cell line constitutively expressing that HIV-1 gene product. In addition, the ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.85.12.4200

    authors： Rice AP,Mathews MB

    更新日期：1988-06-01 00:00:00

  • The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model.

    abstract：:Smallpox has played an unparalleled role in human history and remains a significant potential threat to public health. Despite the historical significance of this disease, we know little about the underlying pathophysiology or the virulence mechanisms of the causative agent, variola virus. To improve our understanding...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0405759101

    authors： Rubins KH,Hensley LE,Jahrling PB,Whitney AR,Geisbert TW,Huggins JW,Owen A,Leduc JW,Brown PO,Relman DA

    更新日期：2004-10-19 00:00:00

  • Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist.

    abstract：:In the present study we have observed that interleukin (IL) 1 alpha or IL-1 beta directly induced expression of human immunodeficiency virus (HIV) in the latently infected human promonocytic cell line U1. In addition, IL-1 synergized with IL-6, but not with tumor necrosis factor, in the upregulation of virus expressio...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.91.1.108

    authors： Poli G,Kinter AL,Fauci AS

    更新日期：1994-01-04 00:00:00

  • Behavioral thermoregulation by turtle embryos.

    abstract：:Mobile ectothermic animals can control their body temperatures by selecting specific thermal conditions in the environment, but embryos--trapped within an immobile egg and lacking locomotor structures--have been assumed to lack that ability. Falsifying that assumption, our experimental studies show that even early sta...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1102965108

    authors： Du WG,Zhao B,Chen Y,Shine R

    更新日期：2011-06-07 00:00:00

  • A difference in the architecture of the surface membrane of normal and virally transformed cells.

    abstract：:Several tissue culture cell lines that were transformed by a tumor virus have been found to react with an agglutinin, while under identical conditions their untransformed parent cell lines did not agglutinate. Since a short treatment of the parent cell line with low concentrations of proteases exposed the same aggluti...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.62.3.994

    authors： Burger MM

    更新日期：1969-03-01 00:00:00

  • Bombyx prothoracicostatic peptides activate the sex peptide receptor to regulate ecdysteroid biosynthesis.

    abstract：:Insect molting and metamorphosis are induced by steroid hormones named ecdysteroids, whose production is regulated by various neuropeptides. We cloned the gene and analyzed the expression of the prothoracicostatic peptide, a unique neuropeptide shown to suppress the production of ecdysteroids in the prothoracic gland ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0907471107

    authors： Yamanaka N,Hua YJ,Roller L,Spalovská-Valachová I,Mizoguchi A,Kataoka H,Tanaka Y

    更新日期：2010-02-02 00:00:00

  • Light-induced psbA translation in plants is triggered by photosystem II damage via an assembly-linked autoregulatory circuit.

    abstract：:The D1 reaction center protein of photosystem II (PSII) is subject to light-induced damage. Degradation of damaged D1 and its replacement by nascent D1 are at the heart of a PSII repair cycle, without which photosynthesis is inhibited. In mature plant chloroplasts, light stimulates the recruitment of ribosomes specifi...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.2007833117

    authors： Chotewutmontri P,Barkan A

    更新日期：2020-09-01 00:00:00

  • CRISPR-Cas9-guided oncogenic chromosomal translocations with conditional fusion protein expression in human mesenchymal cells.

    abstract：:Gene editing techniques have been extensively used to attempt to model recurrent genomic rearrangements found in tumor cells. These methods involve the induction of double-strand breaks at endogenous loci followed by the identification of breakpoint junctions within a population, which typically arise by nonhomologous...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1700622114

    authors： Vanoli F,Tomishima M,Feng W,Lamribet K,Babin L,Brunet E,Jasin M

    更新日期：2017-04-04 00:00:00

  • Biological spectra analysis: Linking biological activity profiles to molecular structure.

    abstract：:Establishing quantitative relationships between molecular structure and broad biological effects has been a longstanding challenge in science. Currently, no method exists for forecasting broad biological activity profiles of medicinal agents even within narrow boundaries of structurally similar molecules. Starting fro...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0407790101

    authors： Fliri AF,Loging WT,Thadeio PF,Volkmann RA

    更新日期：2005-01-11 00:00:00

  • Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas.

    abstract：:Effective therapies for most solid cancers, especially those that have progressed to metastasis, remain elusive because of inherent and acquired resistance of tumor cells to conventional treatments. Additionally, the effective therapeutic window for many protocols can be very narrow, frequently resulting in toxicity. ...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0700042104

    authors： Lebedeva IV,Washington I,Sarkar D,Clark JA,Fine RL,Dent P,Curiel DT,Turro NJ,Fisher PB

    更新日期：2007-02-27 00:00:00

  • A method for high-sensitivity peptide sequencing using postsource decay matrix-assisted laser desorption ionization mass spectrometry.

    abstract：:A method has been developed for de novo peptide sequencing using matrix-assisted laser desorption ionization mass spectrometry. This method will facilitate biological studies that require rapid determination of peptide or protein sequences, e.g., determination of posttranslational modifications, identification of acti...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.96.13.7131

    authors： Keough T,Youngquist RS,Lacey MP

    更新日期：1999-06-22 00:00:00

  • Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease.

    abstract：:Canavan's disease (CD) is a fatal, hereditary disorder of CNS development that has been linked to mutations in the gene for the enzyme aspartoacylase (ASPA) (EC 3.5.1.15). ASPA acts to hydrolyze N-acetylaspartate (NAA) into l-aspartate and acetate, but the connection between ASPA deficiency and the failure of proper C...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0409184102

    authors： Madhavarao CN,Arun P,Moffett JR,Szucs S,Surendran S,Matalon R,Garbern J,Hristova D,Johnson A,Jiang W,Namboodiri MA

    更新日期：2005-04-05 00:00:00

  • Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.

    abstract：:Establishment, specification, and validation of synaptic connections are thought to be mediated by interactions between pre- and postsynaptic cell-adhesion molecules. Arguably, the best-characterized transsynaptic interactions are formed by presynaptic neurexins, which bind to diverse postsynaptic ligands. In a proteo...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1621321114

    authors： Sterky FH,Trotter JH,Lee SJ,Recktenwald CV,Du X,Zhou B,Zhou P,Schwenk J,Fakler B,Südhof TC

    更新日期：2017-02-14 00:00:00

  • An archaeal primase functions as a nanoscale caliper to define primer length.

    abstract：:The cellular replicative DNA polymerases cannot initiate DNA synthesis without a priming 3' OH. During DNA replication, this is supplied in the context of a short RNA primer molecule synthesized by DNA primase. The primase of archaea and eukaryotes, despite having varying subunit compositions, share sequence and struc...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1806351115

    authors： Yan J,Holzer S,Pellegrini L,Bell SD

    更新日期：2018-06-26 00:00:00

  • Discovery and characterization of an epithelial-specific galectin in the endometrium that forms crystals in the trophectoderm.

    abstract：:Secretions of the uterus support survival and growth of the conceptus (embryo/fetus and associated membranes) during pregnancy. Galectin-15, also known as OVGAL11 and a previously uncharacterized member of the galectin family of secreted beta-galactoside lectins containing a conserved carbohydrate recognition domain a...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.0402669101

    authors： Gray CA,Adelson DL,Bazer FW,Burghardt RC,Meeusen EN,Spencer TE

    更新日期：2004-05-25 00:00:00

  • Mitochondrial DNA sequence evolution in the Arctoidea.

    abstract：:Some taxa in the superfamily Arctoidea, such as the giant panda and the lesser panda, have presented puzzles to taxonomists. In the present study, approximately 397 bases of the cytochrome b gene, 364 bases of the 12S rRNA gene, and 74 bases of the tRNA(Thr) and tRNA(Pro) genes from the giant panda, lesser panda, kink...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.90.20.9557

    authors： Zhang YP,Ryder OA

    更新日期：1993-10-15 00:00:00

  • Cryptographic hashing using chaotic hydrodynamics.

    abstract：:Fluids may store and manipulate information, enabling complex applications ranging from digital logic gates to algorithmic self-assembly. While controllable hydrodynamic chaos has previously been observed in viscous fluids and harnessed for efficient mixing, its application to the manipulation of digital information h...

    journal_title：Proceedings of the National Academy of Sciences of the United States of America

    pub_type： 杂志文章

    doi：10.1073/pnas.1721852115

    authors： Gilpin W

    更新日期：2018-05-08 00:00:00