当前位置： SCI文献检索 > MICROBIOLOGY AND IMMUNOLOGY期刊下所有文献 > Mycoplasma pneumoniae infection induces a neutrophil-derived antimicrobial peptide, cathelin-related antimicrobial peptide.

Mycoplasma pneumoniae infection induces a neutrophil-derived antimicrobial peptide, cathelin-related antimicrobial peptide.

Abstract：

:In innate immunity, cationic antimicrobial peptides including cathelin-related antimicrobial peptide (CRAMP) are known to play critical roles in protecting the host from infection by invasive microbes, including Gram-positive and -negative bacteria. However, little is known about the interactions between CRAMP and mycoplasmas. In the present study, the antimicrobial activity of CRAMP against M. pneumoniae and the expression of CRAMP in bronchoalveolar lavage fluid (BALF) of M. pneumoniae-infected mice was examined. CRAMP at 10-20 μg/mL reduced the growth of two strains of M. pneumoniae by 100 to 1000-fold. The amount of CRAMP in the BALF of M. pneumoniae-infected mice was 20∼25 ng/mL by ELISA. The presence of mature CRAMP in BALF was observed by Western blotting. Neutrophils in BALF showed a fair amount of CRAMP in their cytoplasm by immunofluorescence. Furthermore, the addition of M. pneumoniae resulted in the release of a large amount of CRAMP from neutrophils induced by thioglycolate. These results suggest that CRAMP from neutrophils may play an important role in protection against M. pneumoniae infection.

journal_name

Microbiol Immunol

journal_title

Microbiology and immunology

authors

Tani K,Shimizu T,Kida Y,Kuwano K

doi

10.1111/j.1348-0421.2011.00353.x

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

582-8

issue

8

eissn

0385-5600

issn

1348-0421

journal_volume

55

pub_type

杂志文章

相关文献

MICROBIOLOGY AND IMMUNOLOGY文献大全
  • Expression of the colH gene encoding Clostridium histolyticum collagenase in Bacillus subtilis and its application to enzyme purification.

    abstract：:The colH gene encoding 116-kDa collagenase of Clostridium histolyticum (cColH) was cloned into an Escherichia coli-Bacillus subtilis shuttle vector to develop a method for purification of recombinant collagenase (rColH). When plasmid pJCM310 containing the colH gene was introduced into B. subtilis DB104 and the transf...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1996.tb01161.x

    authors： Jung CM,Matsushita O,Katayama S,Minami J,Ohhira I,Okabe A

    更新日期：1996-01-01 00:00:00

  • Fate of Legionella pneumophila in macrophages of C57BL/6 chronic granulomatous disease mice.

    abstract：:We compared the intracellular survival and growth of Legionella pneumophila Philadelphia-1 in peritoneal macrophages obtained from A/J, C57BL/6, and X-linked chronic granulomatous disease (CGD) mice produced from C57BL/6 strain. The initial killing was observed in A/J and C57BL/6 macrophages at 2, 4 and 6 hr after in ...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2001.tb02655.x

    authors： Saito M,Kajiwara H,Miyamoto H,Yoshida S

    更新日期：2001-01-01 00:00:00

  • Evaluation of the biofilm-forming ability and genetic typing for clinical isolates of Pseudomonas aeruginosa by enterobacterial repetitive intergenic consensus-based PCR.

    abstract：:Biofilm formation is an important phenotype associated with chronic Pseudomonas aeruginosa infections. In the present study, a total of 48 P. aeruginosa strains isolated from clinical specimens were examined for their biofilm-forming ability using a microtiter plate method. The different biofilm-forming abilities were...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2005.tb03702.x

    authors： Yang W,Shi L,Jia WX,Yin X,Su JY,Kou Y,Yi X,Shinoda S,Miyoshi S

    更新日期：2005-01-01 00:00:00

  • The role of p38 mitogen-activated protein kinase in regulating interleukin-10 gene expression in Burkitt's lymphoma cell lines.

    abstract：:In malignant B lymphoma cells interleukin-10 (IL-10) expression is frequently upregulated. This effect is thought to support to the malignant transformation of these cells and to be a potential target for pharmacotherapy. To define better the mechanism for upregulation of the IL-10 gene, we tested the association betw...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2007.tb03885.x

    authors： Horie K,Ohashi M,Satoh Y,Sairenji T

    更新日期：2007-01-01 00:00:00

  • Antigenic analysis of flaviviruses with monoclonal antibodies against Negishi virus.

    abstract：:Twelve monoclonal antibodies against Negishi virus were obtained and characterized by hemagglutination inhibition (HI) and neutralization (NT) tests using five flaviviruses isolated in the pan-Pacific region. The reaction pattern of the antibodies showed that Negishi virus was most closely related to Langat virus, fol...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1984.tb00758.x

    authors： Furuta I,Takashima I,Arikawa J,Hashimoto N

    更新日期：1984-01-01 00:00:00

  • Pathogenicity of Bacteroides fragilis group in rat intra-abdominal abscesses.

    abstract：:Attempts were made to study the pathogenicity of some strains of Bacteroides fragilis group in the rat intra-abdominal abscess model. Multiple intraabdominal abscesses were produced in 50 to 70% of animals when an inoculum containing 10(9) CFU/ml of any of the five species of Bacteroides fragilis group was injected. R...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1992.tb02108.x

    authors： Jotwani R,Gupta U,Watanabe K,Ueno K

    更新日期：1992-01-01 00:00:00

  • Characterization of a toxin-deficient Clostridium perfringens strain, KZ1340.

    abstract：:Clostridium perfringens KZ1340, previously classified as Clostridium plagarum, is an isolate from Antarctic soil, and was identified as an alpha-, theta-, and kappa-toxin non-producing variant. On Southern hybridization, the variant was found to be defective in the pfoA (theta-toxin) gene, but the plc (alpha-toxin) an...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1996.tb03329.x

    authors： Shimizu T,Ohtani K,Ba-Thein W,Inui S,Nakamura S,Hayashi H

    更新日期：1996-01-01 00:00:00

  • Distribution of human rotaviruses, especially G9 strains, in Japan from 1996 to 2000.

    abstract：:A 4-year (1996-2000) survey of rotavirus infection involving 2,218 diarrheal fecal specimens of children collected from five regions of Japan was conducted. A total of 642 (28.9%) specimens were found to be rotavirus positive. A changed prevalence pattern of rotavirus G serotype was found with an increase of G9 and G2...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2003.tb03422.x

    authors： Zhou Y,Li L,Okitsu S,Maneekarn N,Ushijima H

    更新日期：2003-01-01 00:00:00

  • Regulation of NF-kappaB signaling by decoy oligodeoxynucleotides.

    abstract：:The nuclear factor-kappa B (NF-kappaB) plays a critical role in regulating expression of genes responsible for a wide range of cellular processes, including innate and adoptive immune responses, and pathways related to cell survival and proliferation. Based on its property as a transcription factor, NF-kappaB has been...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1348-0421.2006.tb03827.x

    authors： Isomura I,Morita A

    更新日期：2006-01-01 00:00:00

  • Variation in virulence of Coxsackie virus B3 in the hearts of mice. I. Comparison of mortality and virus growth in the heart and other organs.

    abstract：:Virulence of Coxsackie virus B3 (CB3) was compared in mice between strain SK-74 isolated from a patient and strain T-70 isolated from a healthy child as well as between prototype strain Nancy and its mouse-passaged derivative strain PMH. Strain SK-74 showed a high mortality (40-80%), while strain T-70 did not induce d...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1983.tb03588.x

    authors： Komatsu T,Hashimoto I,Kohara T

    更新日期：1983-01-01 00:00:00

  • Herpes simplex virus US3 protein kinase regulates host responses and determines neurovirulence.

    abstract：:The US3 of HSV encodes a serine/threonine protein kinase that is highly conserved among members of the alphaherpesviruses. It is an accessory gene that is not required for viral replication in cultured cells but appears essential for viral survival in humans. Although accumulating in vitro evidence suggested that the ...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1348-0421.2012.00461.x

    authors： Mori I

    更新日期：2012-06-01 00:00:00

  • Inhibitory effects of soluble MD-2 and soluble CD14 on bacterial growth.

    abstract：:The effects of the soluble forms of the endotoxin receptor molecules sMD-2 and sCD14 on bacterial growth were studied. When Escherichia coli and Bacillus subtilis were incubated at 37 degrees C for 18 hr with either sMD-2 or sCD14, growth of these bacteria was significantly inhibited as evaluated by viable cell counts...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2009.00186.x

    authors： Ohnishi T,Muroi M,Tanamoto K

    更新日期：2010-02-01 00:00:00

  • Immune responses against allogeneic and syngeneic tumors in aged C57BL/6 mice.

    abstract：:Aged C57BL/6 (B6) mice could reject allogeneic BALB/c RL male 1 tumor as efficiently as young B6 mice. However, in vitro analysis showed impaired generation of cytotoxic T cell response in aged B6 mice against allogeneic tumor. The reaction could be augmented by the addition of recombinant interleukin-2 (rIL-2). Enzym...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2002.tb02728.x

    authors： Win S,Uenaka A,Nakayama E

    更新日期：2002-01-01 00:00:00

  • Participation of macrophages in enhanced in vitro immune interferon (IFN gamma) production with mouse spleen cells.

    abstract：:IFN gamma production in cultures of spleen cells obtained from mice sensitized with TH69, a live Streptococcus faecalis preparation, was examined to determine how macrophages participate. It was demonstrated that sensitized spleen macrophages participated in enhanced IFN gamma production by T cells at an early stage (...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1984.tb00759.x

    authors： Yamaguchi T,Kuroda Y,Yokoyama T,Saito M,Ebina T,Hoshino F,Ishida N

    更新日期：1984-01-01 00:00:00

  • In vitro susceptibility of 7.5-kb common plasmid-free Chlamydia trachomatis strains.

    abstract：:Using a new plaque cloning technique, we obtained unique Chlamydia trachomatis strains which were confirmed to be free of the 7.5-kb common plasmid and glycogen in inclusions. The in vitro susceptibility of these strains to various chemotherapeutic agents was tested by comparison with their parent strains and clinical...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2000.tb02493.x

    authors： Miyashita N,Matsumoto A,Matsushima T

    更新日期：2000-01-01 00:00:00

  • Development of reference material with assigned value for human T-cell leukemia virus type 1 quantitative PCR in Japan.

    abstract：:Quantitative PCR (qPCR) of human T-cell leukemia virus type 1 (HTLV-1) provirus is used for HTLV-1 testing and for assessment of risk of HTLV-1-related diseases. In this study, a reference material was developed for standardizing HTLV-1 qPCR. Freeze-dried TL-Om1 cells diluted with Jurkat cells were prepared and an ass...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/1348-0421.12644

    authors： Kuramitsu M,Okuma K,Nakashima M,Sato T,Sasaki D,Hasegawa H,Umeki K,Kubota R,Sasada K,Sobata R,Matsumoto C,Kaneko N,Tezuka K,Matsuoka S,Utsunomiya A,Koh KR,Ogata M,Ishitsuka K,Taki M,Nosaka K,Uchimaru K,Iwanaga M

    更新日期：2018-10-01 00:00:00

  • Clinical and bacteriological profiles of patients with typhoid fever treated during 1975-1998 in the Tokyo Metropolitan Komagome Hospital.

    abstract：:Patients with typhoid fever presenting to the Tokyo Metropolitan Komagome Hospital during the period 1975-1998 were retrospectively investigated. All cases were diagnosed by a positive culture for Salmonella typhi in either of their clinical specimens. Of the total number of 130 patients, 57% contracted the disease ab...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2000.tb02536.x

    authors： Hoshino Y,Masuda G,Negishi M,Ajisawa A,Imamura A,Hachimori K,Takayama N,Yamaguchi T,Kimura M

    更新日期：2000-01-01 00:00:00

  • Heterologous expression of a gene of Magnaporthe oryzae chrysovirus 1 strain A disrupts growth of the human pathogenic fungus Cryptococcus neoformans.

    abstract：:Magnaporthe oryzae chrysovirus 1 strain A (MoCV1-A) is the causal agent of growth repression and attenuated virulence (hypovirulence) of the rice blast fungus, M. oryzae. We have previously reported that heterologous expression of MoCV1-A ORF4 in Saccharomyces cerevisiae results in growth defects, a large central vacu...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/1348-0421.12148

    authors： Urayama S,Fukuhara T,Moriyama H,Toh-E A,Kawamoto S

    更新日期：2014-05-01 00:00:00

  • Complete genome sequence and characterization of virulence genes in Lancefield group C Streptococcus dysgalactiae isolated from farmed amberjack (Seriola dumerili).

    abstract：:Lancefield group C Streptococcus dysgalactiae causes infections in farmed fish. Here, the genome of S. dysgalactiae strain kdys0611, isolated from farmed amberjack (Seriola dumerili) was sequenced. The complete genome sequence of kdys0611 consists of a single chromosome and five plasmids. The chromosome is 2,142,780 b...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/1348-0421.12716

    authors： Nishiki I,Yoshida T,Fujiwara A

    更新日期：2019-07-01 00:00:00

  • Experimental candida-induced arteritis in mice. Relation to arteritis in the mucocutaneous lymph node syndrome.

    abstract：:An extract of Candida albicans isolated from a patient with typical mucocutaneous lymph node syndrome (MCLS) can produce coronary arteritis in a mouse when injected intraperitoneally. An unusual feature of this arteritis is that it is granulomatous, shows no fibrinoid change and is confined to the coronary arteries. T...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1979.tb02815.x

    authors： Murata H

    更新日期：1979-01-01 00:00:00

  • Distribution of indigenous Lactobacilli in the digestive tract of conventional and gnotobiotic rats.

    abstract：:Distribution of indigenous lactobacilli in the gastrointestinal tracts of rats was investigated at the species level. The indigenous lactobacilli isolated from conventional rats were divided into three groups, Lactobacillus acidophilus and its related strains, L. fermentum, and L. murini. Localization of the Lactobaci...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1977.tb00280.x

    authors： Watanabe T,Morotomi M,Suegara N,Kawai Y,Mutai M

    更新日期：1977-01-01 00:00:00

  • Molecular epidemiology of rabies in Vietnam.

    abstract：:The present study was done to determine the molecular epidemiology of rabies virus (RV) in Vietnam. The nucleoprotein (N) and glycoprotein (G) genes of RVs were amplified from the brains of ten rabid dogs of Ho Chi Minh City, Vietnam. The nucleotide sequences of these genes were compared with those of other Asian stra...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2007.tb03979.x

    authors： Yamagata J,Ahmed K,Khawplod P,Mannen K,Xuyen DK,Loi HH,Dung NV,Nishizono A

    更新日期：2007-01-01 00:00:00

  • Surface characteristics of gram-negative and gram-positive bacteria in an atomic force microscope image.

    abstract：:Bacterial images can be obtained rather easily with an atomic-force microscope (AFM) in the magnification range of 5,000 to 30,000 times without any pretreatment of the specimens for such observations as chemical fixation, dehydration or staining. The bacterial shapes or the presence of flagella can be clearly recogni...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1998.tb02266.x

    authors： Umeda A,Saito M,Amako K

    更新日期：1998-01-01 00:00:00

  • Enhancement of Newcastle disease virus-induced fusion of mouse L cells by sodium vanadate.

    abstract：:Sodium vanadate enhanced Newcastle disease virus (NDV)-induced cell fusion in L cells, and there was a direct correlation between the degree of cell fusion and the dose of vanadate added. When anti-F protein of NDV monospecific antiserum was added to the culture fluid of L cells infected with NDV, the enhancement of c...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1984.tb02948.x

    authors： Yamamoto F,Fujioka H,Iinuma M,Takano M,Maeno K,Nagai Y,Ito Y

    更新日期：1984-01-01 00:00:00

  • Molecular ratio between borna disease viral-p40 and -p24 proteins in infected cells determined by quantitative antigen capture ELISA.

    abstract：:We developed the antigen capture enzyme-linked immunosorbent assay (ELISA) systems for quantification of Borna disease virus (BDV) major antigens, p40 and p24. Using these ELISAs, we quantified the two proteins in various BDV-infected materials, including the cell lysates and culture supernatants as well as the homoge...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2000.tb02561.x

    authors： Watanabe M,Zhong Q,Kobayashi T,Kamitani W,Tomonaga K,Ikuta K

    更新日期：2000-01-01 00:00:00

  • Detection of human cytomegalovirus DNA in breast milk by means of polymerase chain reaction.

    abstract：:Three hundred and twenty-five breast milk samples were examined for the occurrence of human cytomegalovirus (HCMV) by cell culture method. Virus was isolated from the milk in 1 of 177 samples collected within 6 days after delivery, 2 of 115 samples collected during the period of 7 days to 1 month after delivery, 10 of...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1994.tb01862.x

    authors： Hotsubo T,Nagata N,Shimada M,Yoshida K,Fujinaga K,Chiba S

    更新日期：1994-01-01 00:00:00

  • Virulence of representative Japanese Francisella tularensis and immunologic consequences of infection in mice.

    abstract：:Francisella tularensis, which causes tularemia, is widely distributed in the Northern hemisphere. F. tularensis strains isolated in Japan are genetically unique from non-Japanese strains; however, their phenotypic properties have not been well studied. Thus, mice were infected with representative Japanese strains of F...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/1348-0421.12363

    authors： Hotta A,Fujita O,Uda A,Yamamoto Y,Sharma N,Tanabayashi K,Yamada A,Morikawa S

    更新日期：2016-03-01 00:00:00

  • Delayed HIV-1 infection of CD4+ T lymphocytes from therapy-naïve patients demonstrated by quantification of HIV-1 DNA copy numbers.

    abstract：:Measuring the amount of HIV-1 DNA in infected cells is important to estimate the size of the viral reservoir in patients. However, the clinical impact of the intracellular viral DNA level remains unclear. The present study examines the clinical significance of the HIV-1 DNA level in peripheral CD4+ T lymphocytes from ...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.2004.tb03603.x

    authors： Wada K,Nagai H,Hagiwara T,Ibe S,Utsumi M,Kaneda T

    更新日期：2004-01-01 00:00:00

  • Inherited deficiency of the seventh component of complement associated with meningococcal meningitis: lack of serum bactericidal activity against Neisseria meningitidis in a girl with C7 deficiency and HLA studies of a C7-deficient Japanese family.

    abstract：:An 8-year-old girl with meningococcal meningitis lacked serum complement activity. The seventh component of complement (C7) could not be detected in her serum by either functional or immunochemical analysis. The levels of the other components were within the normal range. Her serum complement activity was restored by ...

    journal_title：Microbiology and immunology

    pub_type： 杂志文章

    doi：10.1111/j.1348-0421.1986.tb00953.x

    authors： Miyake T,Ohta K,Kawamori J,Hirao T,Akagaki Y,Inai S

    更新日期：1986-01-01 00:00:00

  • In vivo safety assessment of two Bifidobacterium longum strains.

    abstract：:Bifidobacteria are important members of the intestinal microbiota and are considered to contribute to maintaining health. However, the level of bifidobacteria colonising the intestine of elderly subjects tends to be lower than in younger adults. Therefore, two Bifidobacterium longum strains, isolated from healthy elde...

    journal_title：Microbiology and immunology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1348-0421.2003.tb03464.x

    authors： Mäkeläinen H,Tahvonen R,Salminen S,Ouwehand AC

    更新日期：2003-01-01 00:00:00