Burkholderia pseudomallei-induced expression of a negative regulator, sterile-alpha and Armadillo motif-containing protein, in mouse macrophages: a possible mechanism for suppression of the MyD88-independent pathway.

abstract：:Peptidoglycan from a Staphylococcus epidermidis strain, isolated from a patient with septicemia, was preincubated with human serum. This mixture was then investigated for its potency to induce tumor necrosis factor (TNF) secretion by human blood monocytes. TNF was measured in the supernatants by using a bioassay and/o...

journal_title：Infection and immunity

authors： Mattsson E,Rollof J,Verhoef J,Van Dijk H,Fleer A

更新日期：1994-09-01 00:00:00

abstract：:The antiphagocytic effect of the Staphylococcus aureus capsule is known to be related to its ability to interfere with opsonization by normal human serum. In this study, evidence is presented with isolated cell surface components which indicates that the capsule hinders opsonization by masking cell wall peptidoglycan....

journal_title：Infection and immunity

authors： Wilkinson BJ,Peterson PK,Quie PG

更新日期：1979-02-01 00:00:00

abstract：:Rabbit endogenous pyrogens were of about the same molecular size, but showed considerable heterogeneity of their isoelectric points. We attempted to show that this heterogeneity was attributable to variable glycosylation of a single polypeptide chain. When peritoneal exudate cells were stimulated to make pyrogens in t...

journal_title：Infection and immunity

authors： Murphy PA,Cebula TA,Windle BE

更新日期：1981-10-01 00:00:00

abstract：:Escherichia coli D2 (serotype 07:H-) that was isolated from a child with diarrhea hybridized with an F1845 DNA probe used to detect diffuse adherence. Strain D2 adhered to tissue culture cells (HeLa and HEp-2 cells) in a clustered pattern but did not autoagglutinate on the cell surface and induced the elongation of mi...

journal_title：Infection and immunity

authors： Yamamoto T,Kaneko M,Changchawalit S,Serichantalergs O,Ijuin S,Echeverria P

更新日期：1994-07-01 00:00:00

abstract：:Bordetella pertussis fimbriae are composed of a major subunit, Fim2 or Fim3, and the minor subunit FimD. Using immunoelectron microscopy, we provide evidence that FimD is located at the fimbrial tip. The role of FimD in colonization of the mouse respiratory tract was studied by using two fimbrial mutants: a mutant com...

journal_title：Infection and immunity

authors： Geuijen CA,Willems RJ,Bongaerts M,Top J,Gielen H,Mooi FR

更新日期：1997-10-01 00:00:00

abstract：:Conidia ingested by resident macrophages had an enhanced percentage of transformation to yeast cells compared with those in culture medium without macrophages. The yeast cells subsequently grew intracellularly by budding. Macrophages treated with cytokines from antigen-stimulated spleen cells from immunized mice signi...

journal_title：Infection and immunity

authors： Cano LE,Brummer E,Stevens DA,Restrepo A

更新日期：1992-05-01 00:00:00

abstract：:Previous work in our laboratory has shown that corticosterone increases the susceptibility of macrophages from Bcgs mice to the growth of Mycobacterium avium. The innate antimycobacterial activity of macrophages from Bcgr mice was not affected by corticosterone. In contrast to the differential effect of corticosterone...

journal_title：Infection and immunity

authors： Brown DH,LaFuse W,Zwilling BS

更新日期：1995-08-01 00:00:00

abstract：:Epitope mapping of outer surface protein C (OspC) by using sera from patients with neuroborreliosis led to the identification of one single major immunodominant epitope within the C-terminal 10 amino acid residues. Peptide binding studies and alanine replacement scanning of the C-terminal decapeptide, PVVAESPKKP, reve...

journal_title：Infection and immunity

authors： Mathiesen MJ,Holm A,Christiansen M,Blom J,Hansen K,Ostergaard S,Theisen M

更新日期：1998-09-01 00:00:00

abstract：:Whooping cough results from infection of the respiratory tract with Bordetella pertussis, and the secreted adenylate cyclase toxin (ACT) is essential for the bacterium to establish infection. Despite extensive study of the mechanism of ACT cytotoxicity and its effects over a range of concentrations in vitro, ACT has n...

journal_title：Infection and immunity

authors： Eby JC,Gray MC,Warfel JM,Paddock CD,Jones TF,Day SR,Bowden J,Poulter MD,Donato GM,Merkel TJ,Hewlett EL

更新日期：2013-05-01 00:00:00

abstract：:Intravenous injection of rat anti-mouse gamma interferon (IFN-gamma) monoclonal antibody as well as rabbit anti-mouse tumor necrosis factor (TNF) antibody into mice which had received a sublethal infection with Listeria monocytogenes cells resulted in acceleration of listeriosis. Endogenous IFN-gamma seemed to be prod...

journal_title：Infection and immunity

authors： Nakane A,Minagawa T,Kohanawa M,Chen Y,Sato H,Moriyama M,Tsuruoka N

更新日期：1989-11-01 00:00:00

abstract：:We have focused on regions of staphylococcal enterotoxin C1 (SEC1) causing immunomodulation. N-terminal deletion mutants lacking residues 6 through 13 induced T-cell proliferation similar to that induced by native toxin. However, mutants with residues deleted between positions 19 and 33, although nonmitogenic themselv...

journal_title：Infection and immunity

authors： Hoffmann ML,Jablonski LM,Crum KK,Hackett SP,Chi YI,Stauffacher CV,Stevens DL,Bohach GA

更新日期：1994-08-01 00:00:00

abstract：:Salmonella enterica serovar Typhimurium employs two different type III secretion systems (TTSS) encoded within Salmonella pathogenicity islands 1 and 2 (SPI1 and SPI2) for targeting of effector proteins into the cytosol of eukaryotic cells during different stages of the infection cycle. The SPI1 TTSS translocates viru...

journal_title：Infection and immunity

authors： Panthel K,Meinel KM,Domènech VE,Retzbach H,Igwe EI,Hardt WD,Rüssmann H

更新日期：2005-01-01 00:00:00

abstract：:Escherichia coli O157:H7 is an important pathogen of humans. Cattle are most frequently identified as the primary source of infection, and therefore, reduction in E. coli O157:H7 prevalence in cattle by vaccination represents an attractive strategy for reducing the incidence of human disease. H7 flagella have been imp...

journal_title：Infection and immunity

authors： McNeilly TN,Naylor SW,Mahajan A,Mitchell MC,McAteer S,Deane D,Smith DG,Low JC,Gally DL,Huntley JF

更新日期：2008-06-01 00:00:00

abstract：:Adhesion of Trichomonas vaginalis is believed to be dependent on four adhesion proteins, which are thought to bind to vaginal epithelial cells in a specific manner with a ligand-receptor type of interaction. However, the specific receptors on the host cell have not yet been identified. In this work, the ability of the...

journal_title：Infection and immunity

authors： Addis MF,Rappelli P,Fiori PL

更新日期：2000-07-01 00:00:00

abstract：:Restoration of the ability of hypogammaglobulinemic serum to support opsonophagocytosis and intracellular killing of Bacteroides fragilis and Bacteroides thetaiotaomicron by human polymorphonuclear leukocytes was achieved by supplementation with normal human immunoglobulin M, but not with normal human immunoglobulin G...

journal_title：Infection and immunity

authors： Bjornson AB,Bjornson HS,Kitko BP

更新日期：1980-05-01 00:00:00

abstract：:Natural antibodies are those immunoglobulin molecules found in mammalian serum that arise in the absence of exposure to environmental pathogens and may comprise an early host defense against invading pathogens. The spirochete Borrelia burgdorferi first encounters natural antibodies when its arthropod vector, Ixodes sc...

journal_title：Infection and immunity

authors： Belperron AA,Bockenstedt LK

更新日期：2001-10-01 00:00:00

abstract：:Mice immunized intravenously 10 days earlier (but not those immunized 2 months earlier) with an attenuated Salmonella typhimurium SL3261 aroA live vaccine and tested for delayed-type hypersensitivity by injection of crude Salmonella extracts in the footpad can die within 24 to 48 h of an unexplained allergic reaction....

journal_title：Infection and immunity

authors： Mastroeni P,Villarreal-Ramos B,Harrison JA,Demarco de Hormaeche R,Hormaeche CE

更新日期：1994-06-01 00:00:00

abstract：:The Yersinia enterocolitica gsrA gene is a stress protein gene which was originally identified as essential for protecting cells under both extracellular environmental stress and intracellular stress in macrophages due to phagocytosis. The gsrA gene was shown to be a member of the htrA class of genes and to possess a ...

journal_title：Infection and immunity

authors： Yamamoto T,Hanawa T,Ogata S,Kamiya S

更新日期：1997-06-01 00:00:00

abstract：:The immune response of humans and mice to temperature-specific, plasmid- or chromosome-encoded proteins of yersinia pestis and Yersinia enterocolitica was investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting. Extracts from Y. pestis and Y. enterocolitica strains with and witho...

journal_title：Infection and immunity

authors： Mazza G,Karu AE,Kingsbury DT

更新日期：1985-06-01 00:00:00

abstract：:CD14, the leukocyte receptor for lipopolysaccharide (LPS), is important in the response of human polymorphonuclear leukocytes (PMNs) to infection with gram-negative bacteria. The level of CD14 on the PMN surface increases after exposure to some inflammatory stimuli such as N-formyl-methionyl-leucyl-phenylalanine (fMLP...

journal_title：Infection and immunity

authors： Rodeberg DA,Morris RE,Babcock GF

更新日期：1997-11-01 00:00:00

abstract：:The gene encoding the 35-kDa immunogenic Treponema pallidium subsp. pallidum (T. pallidum) membrane protein C, TmpC, was cloned, sequenced, and expressed in Escherichia coli. The deduced amino acid sequence carries on N-terminal signal sequence with a four-amino-acid motif, which is characteristic for bacterial lipopr...

journal_title：Infection and immunity

authors： Schouls LM,van der Heide HG,van Embden JD

更新日期：1991-10-01 00:00:00

abstract：:Studies were performed to determine the optimal sites for primary isolation of Mycoplasma pulmonis from the respiratory system of laboratory rats. In a preliminary study, a group of 42 rats was cultured for respiratory M. pulmonis at several sites. Tracheal washes yielded the highest number of positive cultures (61.9%...

journal_title：Infection and immunity

authors： Lentsch RH,Wagner JE,Owens DR

更新日期：1979-11-01 00:00:00

abstract：:Surface layer proteins (SLPs) are essential for induction of abortion by Campylobacter fetus subsp. fetus in experimentally challenged ewes. These proteins are encoded by multiple sap genes and vary in size and antigenicity. The role of SLP antigenic variation during experimental ovine infection was investigated. Foll...

journal_title：Infection and immunity

authors： Grogono-Thomas R,Blaser MJ,Ahmadi M,Newell DG

更新日期：2003-01-01 00:00:00

abstract：:Antibodies against mumps virus have been studied by using immunoglobulin class-specific indicators labeled with (125)I in the radioimmunoassay (RIA) procedure. The immunoglobulins in paired acute and convalescent sera were allowed to react with mumps virus in a solid-phase RIA system. Class-specific immunoglobulin ind...

journal_title：Infection and immunity

authors： Daugharty H,Warfield DT,Hemingway WD,Casey HL

更新日期：1973-03-01 00:00:00

abstract：:Variable subregions within the variant surface glycoprotein (VSG) coat displayed by African trypanosomes are predicted sites for T- and B-cell recognition. Hypervariable subregion 1 (HV-1) is localized to an internal amphipathic alpha helix in VSG monomers and may have evolved due to selective pressure by host T-cell ...

journal_title：Infection and immunity

authors： Dagenais TR,Demick KP,Bangs JD,Forest KT,Paulnock DM,Mansfield JM

更新日期：2009-01-01 00:00:00

abstract：:Mice were infected with 170 Trichinella spiralis larvae, and their blood clearance of carbon particles was studied 4, 7, 13, 32, and 135 days later and compared with that of noninfected control mice. Clearance in mice with a 4-day-old infection was comparable to that in the controls; clearances in mice with 7- and 13-...

journal_title：Infection and immunity

authors： Barriga OO

更新日期：1980-12-01 00:00:00

abstract：:During a Plasmodium chabaudi infection in interleukin-10 (IL-10) knockout mice, there is greater parasite sequestration, more severe cerebral edema, and a high frequency of cerebral hemorrhage compared with infection of C57BL/6 mice. Anti-tumor necrosis factor alpha treatment ameliorated both cerebral edema and hemorr...

journal_title：Infection and immunity

authors： Sanni LA,Jarra W,Li C,Langhorne J

更新日期：2004-05-01 00:00:00

abstract：:The immunogenicity of a single dose of a whole-cell vaccine of inactivated Borrelia burgdorferi HSF (human spinal fluid isolate) was evaluated. Syrian hamsters were vaccinated subcutaneously and challenged by the intraperitoneal injection of 1,000 50% infectious doses of B. burgdorferi HSF 30 or 90 days postvaccinatio...

journal_title：Infection and immunity

authors： Johnson RC,Kodner C,Russell M

更新日期：1986-12-01 00:00:00

abstract：:Differences in susceptibility to persistent cryptosporidial infection between two strains of adult athymic nude mice prompted us to investigate the immune mechanism(s) that may control resistance to infection in these T-cell-deficient mice. We studied fecal oocyst shedding, serum and fecal parasite-specific antibody r...

journal_title：Infection and immunity

authors： Adjei AA,Jones JT,Riggs MW,Enriquez FJ

更新日期：1999-08-01 00:00:00

abstract：:Candida albicans is a ubiquitous mucosal commensal that is normally prevented from causing acute or chronic invasive disease. Neutrophils contribute to protection in oral infection but exacerbate vulvovaginal candidiasis. To dissect the role of neutrophils during mucosal candidiasis, we took advantage of a new, transp...

journal_title：Infection and immunity

authors： Gratacap RL,Scherer AK,Seman BG,Wheeler RT

更新日期：2017-08-18 00:00:00