Abstract：
:Dengue virus nonstructural protein 1 (NS1) is a glycoprotein involved in viral RNA replication. NS1 associates with host cell proteins and can be found in lipid raft domains on the host cell surface, suggesting an involvement in signal transduction events. In this work, we observed that NS1 expression in HepG2 cells increases nuclear translocation of NF-κB p65 protein, which was paralleled by DNA-protein complex formation. Luciferase assays showed an increase in NF-κB transcriptional activities in NS1-expressing cells when compared to parental cells. NS1 may enhance NF-κB function in host cells and contribute to the pathogenesis of dengue.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Silva BM,Sousa LP,Gomes-Ruiz AC,Leite FG,Teixeira MM,da Fonseca FG,Pimenta PF,Ferreira PC,Kroon EG,Bonjardim CAdoi
10.1007/s00705-011-0969-0subject
Has Abstractpub_date
2011-07-01 00:00:00pages
1275-9issue
7eissn
0304-8608issn
1432-8798journal_volume
156pub_type
杂志文章abstract：:Chimeric plant viruses are emerging as promising vectors for use in innovative vaccination strategies. In this context, cucumber mosaic virus (CMV) has proven to be a suitable carrier of the hepatitis C virus (HCV)-derived R9 mimotope. In the present work, a new chimeric CMV, expressing on its surface the HCV-derived ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0916-7
更新日期：2007-01-01 00:00:00
abstract：:In order to determine the prevalence of multiple infections with hepatitis viruses in chronic HBsAg carriers in Naples, to assess the interaction between HBV, HDV and HCV infections and to evaluate the influence of multiple virus hepatitis infections on the clinical presentation, we studied 198 HBsAg chronic carriers ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050090
更新日期：1997-01-01 00:00:00
abstract：:The gene coding for the nucleocapsid protein NP of the influenza A virus recombinant strain 413 1,1 was characterized biochemically by molecular hybridization and fingerprint analysis. The data presented suggest that this NP gene has evolved by intracistronic recombination between NP genes of virus N and the fowl plag...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322701
更新日期：1980-01-01 00:00:00
abstract：:The first sporadic cases of Fujian/411/02-lineage viruses were recorded in Finland in winter 2001-2002. The first protracted but low-intensity outbreak occurred here during the first half of 2003, and the second outbreak early in autumn 2003, after detection of sporadic influenza A cases in the summer. The calculated ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0635-5
更新日期：2006-02-01 00:00:00
abstract：:We have studied the biological and molecular characteristics of a MNSV isolate collected in Spain (MNSV-Malpha5) and generated a full-length cDNA clone from which infectious RNA transcripts can be produced. The host range of MNSV-Malpha5 appeared to be limited to cucurbits and did not differ from that of MNSV-Dutch [4...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0927-y
更新日期：2003-03-01 00:00:00
abstract：:Here, we report a novel member of the genus Polerovirus, zucchini aphid-borne yellows virus (ZABYV), which was identified in zucchini grown for seed production in the Xinjiang Uygur Autonomous Region, China. The complete nucleotide sequence of the ZABYV genome was determined and found to be 5,792 nucleotides in length...
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doi：10.1007/s00705-019-04217-w
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abstract：:Fragaria (strawberry) and Rubus species (blackberry, wild blackberry, red raspberry and black raspberry) were thought to be infected with distinct isolates of Tobacco streak virus (TSV). Employing serology and nucleic acid hybridization it has been shown that these isolates form a cluster distinct from other strains o...
journal_title：Archives of virology
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doi：10.1007/s00705-004-0330-y
更新日期：2004-10-01 00:00:00
abstract：:The temperature sensitivity of herpes simplex virus type 1 (HSV-1) was assessed in primary cultures of mouse central nervous system (MNS) cells and mouse embryo cells (MEC). Infectious yields were determined and the ultrastructural morphogenesis of HSV-1 particles was compared following incubation at 37 or 40.5 degree...
journal_title：Archives of virology
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doi：10.1007/BF01309574
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pub_type： 杂志文章
doi：10.1007/s00705-020-04780-7
更新日期：2020-11-01 00:00:00
abstract：:The present study confirms that herpesviruses (LF) previously isolated from testes and buffy coat cells of male turkeys with semen abnormalities establish a latent infection in testicular cells. These experiments also present the first evidence that these herpesviruses are harbored latently in cells of spinal ganglia....
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doi：10.1007/BF01311163
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pub_type： 杂志文章
doi：10.1007/s00705-008-0111-0
更新日期：2008-01-01 00:00:00
abstract：:Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070038
更新日期：2000-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0679-z
更新日期：2010-07-01 00:00:00
abstract：:For selecting the neutralizing monoclonal antibodies (N-MAbs) directed to VP4 of rotavirus strain K8, which has unique VP4 neutralization epitopes, we prepared several reassortant viruses by mixed infection of two different strains K8 (serotype 1) and P (serotype 3) in vitro: three reassortant clones having VP4 of K8 ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316751
更新日期：1991-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01318146
更新日期：1975-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050020
更新日期：2000-01-01 00:00:00
abstract：:Hepatitis B virus (HBV) infection has a major effect on health care systems, with about one-third of the world's population currently infected with the virus. There is an effective vaccine against HBV, which contains a recombinant "surface antigen" produced in an expression vector. Vaccination has proved to be success...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0206-7
更新日期：2008-01-01 00:00:00
abstract：:Sixteen patients with symptoms typical for Ockelbo disease (rash, arthralgia, fever) were enrolled in a 2 1/2 year study, during which clinical symptoms were recorded and ELISA was employed to study specific IgM, IgG and IgG subclass development. Initially, all patients presented with rash and arthralgia, and five pat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01379107
更新日期：1994-01-01 00:00:00
abstract：:African swine fever virus (ASFV) was detected in wild boar in eastern Poland in early 2014. So far, 65 cases of ASFV infection in wild boar have been recognised. The methods used for ASFV detection included highly specific real-time PCR with a universal probe library (UPL), enzyme-linked immunosorbent assay (ELISA), a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2650-5
更新日期：2016-01-01 00:00:00
abstract：:The diagnosis of cytomegalovirus retinitis (CMV-R) is difficult and usually based on clinical criteria or invasive diagnostic procedures. The purpose of this study was to investigate a possible association between CMV-R and specific anti-CMV antibodies in tears. Paired tear and serum samples were obtained from 96 indi...
journal_title：Archives of virology
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doi：10.1007/s00705-006-0813-0
更新日期：2006-12-01 00:00:00
abstract：:Zika virus (ZIKV) has been endemic in Southeast Asian countries for several years, but the presence of the virus has not been associated with significant outbreaks of infection unlike other countries around the world where the Asian lineage ZIKV was introduced recently. However, few studies have been undertaken using ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-04137-1
更新日期：2019-03-01 00:00:00
abstract：:The taxonomy of herpesviruses has been updated by the International Committee on Taxonomy of Viruses (ICTV). The former family Herpesviridae has been split into three families, which have been incorporated into the new order Herpesvirales. The revised family Herpesviridae retains the mammal, bird and reptile viruses, ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0278-4
更新日期：2009-01-01 00:00:00
abstract：:The gene encoding the capsid protein of a genogroup I Norwalk-like virus (NLV) (Hu/NLV/Stav/95/Nor) was cloned and expressed in insect cells using a baculovirus vector. The His-tagged recombinant capsid protein (rStav) was antigenic and immunogenic, showed an apparent molecular weight of approximately 68 kD in protein...
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pub_type： 杂志文章
doi：10.1007/s007050050665
更新日期：2000-01-01 00:00:00
abstract：:Morbillivirus infection of marine mammals has been documented across all of the world's oceans. Whilst infection is generally demonstrated using a variety of histopathological and serological techniques, where possible, the use of molecular techniques is being used to enable accurate genetic typing of virus strains th...
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更新日期：2011-10-01 00:00:00
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doi：10.1007/BF01309701
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abstract：:The Sindbis replicon expression system was used to express La Crosse (LAC) virus envelope glycoprotein genes in both mammalian and mosquito cell culture. Replicon expressed LAC proteins had correct molecular mass (Mr) and were antigenically similar to wild type LAC envelope proteins. In addition, LAC G1 and G2 protein...
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pub_type： 杂志文章
doi：10.1007/s007050050381
更新日期：1998-01-01 00:00:00
abstract：:Chikungunya fever is self-limiting. However, neurological and hemorrhagic complications have been seen in recent outbreaks. The clinical manifestations of this disease are similar to those of dengue virus infection, indicating the need for differential diagnosis in areas such as India, which are endemic for both virus...
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更新日期：2015-10-01 00:00:00
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更新日期：2019-05-01 00:00:00
abstract：:A simultaneous decay of the expression of Im 140 kDa, Im 150 kDa and Im 160 kDa high MW membrane antigens, concomitant with the cell proliferation arrest, was observed during erythropoietin induced differentiation of ts 34 AEV-transformed erythroid cells cultivated at the restrictive temperature. Expression of embryo-...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310975
更新日期：1987-01-01 00:00:00
