Abstract：
:Inpp5f-v3 is a transcriptional variant of Inpp5f (inositol polyphosphate-5-phosphatase F) and locates in distal mouse chromosome 7. It is a paternally expressed imprinted gene in mouse. In this study, we examined the spatiotemporal patterns of Inpp5f-v3 gene during the mouse development. The northern blotting analysis revealed that only one transcript approx 2.7 kb of Inpp5f-v3 was detected in brain. The signals were only observed in brain by the whole-mount in situ hybridization at embryonic day 11.5 (E11.5). The results of quantitative real-time PCR (QRT-PCR) showed that the expression of Inpp5f-v3 increased gradually from the E11.5 to E17.5 and reached the highest at E17.5, then decreased at E18.5 during the brain development. Inpp5f-v3 gene was strongly expressed in the cerebral cortex, olfactory bulb, external germinal layer of cerebellum and ventricular zone (Vz) during the embryonic development (E15.5-E19.5), whereas the expression increased in the olfactory bulb and the cerebellum after birth by using in situ hybridization. The results also demonstrated that the expression of Inpp5f-v3 gene mainly located in olfactory bulb and hippocampus at postnatal day 7 (P7) and adulthood. These results suggest that Inpp5f-v3 is specifically expressed in mouse brain, and may function in the development of mouse brain.
journal_name
J Mol Histoljournal_title
Journal of molecular histologyauthors
Yan C,Hongjuan H,Yanjiang X,Zhengbin H,Kai L,Fengwei Z,Jing H,Qiong Wdoi
10.1007/s10735-011-9321-ysubject
Has Abstractpub_date
2011-04-01 00:00:00pages
167-73issue
2eissn
1567-2379issn
1567-2387journal_volume
42pub_type
杂志文章abstract：:The accurately establishment of the eruptive pathway is of vital importance. The mechanisms governing tooth eruption pathway remain little known. This study is to elucidate the roles of Semaphorin 3A (Sema 3A) in mouse tooth eruptive pathway. C57BL/6 mice (11-13 and 15-17 days after birth) were chosen to observe erupt...
journal_title：Journal of molecular histology
pub_type： 杂志文章
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更新日期：2019-10-01 00:00:00
abstract：:Elevated expression of CXCL9 has been shown to involve in the infiltration of inflammatory cells and liver damage after Hepatitis B virus (HBV) infection. However, whether and by what underlying mechanism does CXCL9 play a role in HBV infection associated hepatocellular carcinoma (HCC) invasion ability remain unclear....
journal_title：Journal of molecular histology
pub_type： 杂志文章
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更新日期：2014-12-01 00:00:00
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journal_title：Journal of molecular histology
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doi：10.1007/s10735-013-9490-y
更新日期：2013-06-01 00:00:00
abstract：:Immunohistochemical and fluorescent in situ hybridization (FISH) assays are useful diagnostic methods for the identification of bacteria on formalin fixed paraffin embedded histological sections. To validate an anti-bacterial antibody or an oligonucleotide probe and to ensure fidelity during subsequent analyses, suita...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-008-9173-2
更新日期：2008-08-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1023/b:hijo.0000021089.75408.7c
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abstract：:Objective Oligodendroglial tumors with a loss of heterozygosity of 1p (LOH1p) appear to have a better prognosis than oligodendrogliomas without LOH. Previously, we reported glucose uptake in low-grade oligodendroglial tumors to be related to LOH 1p status. Here, we performed an immunohistochemical study of the common ...
journal_title：Journal of molecular histology
pub_type： 杂志文章
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更新日期：2008-10-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
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更新日期：2020-10-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-016-9671-6
更新日期：2016-06-01 00:00:00
abstract：:Stromal cells in the peripheral zone (PZ) of the prostate from older males (PZ-old) could significantly promote Prostate cancer (PCa) growth compared with stromal cells from young males (PZ-young). But the mechanism is still unknown. In the co-culture system with PZ-old cells, Pc3/Du145 cells showed advanced prolifera...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-016-9679-y
更新日期：2016-06-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-019-09810-6
更新日期：2019-04-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-019-09823-1
更新日期：2019-06-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-020-09918-0
更新日期：2020-12-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-017-9753-0
更新日期：2018-04-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-013-9486-7
更新日期：2013-06-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-017-9731-6
更新日期：2017-12-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/10.1007/s10735-004-1318-3
更新日期：2004-06-01 00:00:00
abstract：:Prostate cancer is the most common cancer in American men and the second leading cause of cancer deaths in this group. Both growth hormone (GH) and the inflammatory cytokine interleukin 6 (IL-6) have been implicated in prostate cancer progression. Studies in other systems have shown that an increase in GH results in a...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-006-9027-8
更新日期：2006-01-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
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更新日期：2004-05-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-009-9218-1
更新日期：2009-04-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 撤回出版物,收录出版
doi：10.1007/s10735-015-9642-3
更新日期：2016-04-01 00:00:00
abstract：:Submandibular gland (SMG) autotransplantation is an effective therapy for treating severe dry eye syndrome. However, epiphora occurs in more than 40% of patients 6 months after operation. We previously found that muscarinic acetylcholine receptor (mAChR) plays a crucial role in regulating SMG secretion partially throu...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-016-9709-9
更新日期：2017-04-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-019-09829-9
更新日期：2019-08-01 00:00:00
abstract：:Alveolar macrophages (AMs) play a vital role in lung immunity. The recent studies demonstrated that potassium channels were associated with macrophage functions, such as activation, migration and cytokines secretion. However, less is known regarding the expression and function of ERG channels in AMs. Our study showed ...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-012-9458-3
更新日期：2013-02-01 00:00:00
abstract：:Selective cyclooxygenase-2 non-steroidal anti-inflammatory drugs are known to inhibit bone repair, especially when long-term administration is required due to chronicle inflammatory diseases. In order to evaluate the action of this drug in bone repair during short-term administration, 48 rats underwent surgical bone d...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-008-9176-z
更新日期：2008-08-01 00:00:00
abstract：:The natriuretic peptide (NP) system comprises of three ligands, the Atrial Natriuretic Peptide (ANP), Brain Natriuretic peptide (BNP) and C-type Natriuretic peptide (CNP), and three natriuretic peptide receptors, NPRA, NPRB and NPRC. Here we present a comprehensive study of the natriuretic peptide system in healthy mu...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-019-09849-5
更新日期：2020-02-01 00:00:00
abstract：:p53 plays a pivotal role in the prevention of human tumor formation. p73 and p63 are new members of the p53 tumor suppressor family, which are becoming increasingly recognized as important players in human tumorigenesis. However, the roles of these proteins are not well elucidated in extrahepatic bile duct (EBD) carci...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-007-9084-7
更新日期：2007-06-01 00:00:00
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journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-013-9521-8
更新日期：2013-12-01 00:00:00
abstract：:Soluble epoxide hydrolase (sEH) is a bifunctional enzyme with a C-terminal epoxide hydrolase activity and an N-terminal phosphatase activity. Arachidonic acid epoxides, previously suggested to be involved in apoptosis, oncogenesis and cell proliferation, are generated by cytochrome P450 epoxygenases and are good subst...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-006-9050-9
更新日期：2006-05-01 00:00:00
abstract：:MI-ER1 is a novel transcriptional regulator that plays a critical role in embryonic development and is differentially expressed in breast carcinoma. The MI-ER1 protein sequence is highly conserved among species, with 95% identity between mouse and humans and 72% between Xenopus and mouse. There are two major protein i...
journal_title：Journal of molecular histology
pub_type： 杂志文章
doi：10.1007/s10735-007-9116-3
更新日期：2008-02-01 00:00:00
