KDM3A confers metastasis and chemoresistance in epithelial ovarian cancer.

abstract：:Angiotensin II (Ang II) has been reported to cause podocyte apoptosis in rats both in vivo and in vitro studies. However, the underlying mechanisms are poorly understood. In the present study, we investigated the role of the nonreceptor tyrosine kinase c-Abl in Ang II-induced podocyte apoptosis. Male Sprague-Dawley ra...

journal_title：Journal of molecular histology

authors： Chen X,Ren Z,Liang W,Zha D,Liu Y,Chen C,Singhal PC,Ding G

更新日期：2013-10-01 00:00:00

abstract：:Epidermal adult stem cells (EpiASCs) have the potential for unlimited proliferation and differentiation, however, the ability of these stem cells to activate corneal genetic programs in response to corneal stroma stimulation needs to be further validated. Herein, a feasible strategy was developed to reconstruct the da...

journal_title：Journal of molecular histology

authors： Zhang P,Ma XY,Huang DT,Yang XY

更新日期：2020-06-01 00:00:00

abstract：:Five subtypes of dopamine receptor exist in two subfamilies: two D(1)-like (D(1) and D(5)) and three D(2)-like (D(2), D(3) and D(4)). We produced novel monoclonal antibodies against all three D(2)-like receptors and used them to localize receptors in Ntera-2 (NT-2) cells, the human neuronal precursor cell line. Most o...

journal_title：Journal of molecular histology

authors： Wolstencroft EC,Simic G,thi Man N,Holt I,Lam le T,Buckland PR,Morris GE

更新日期：2007-08-01 00:00:00

abstract：:Nel-like molecule-1 (NELL-1) is a novel highly specific growth factor that can induce osteoblast differentiation and bone formation as well as odontoblast differentiation. Recent studies have suggested that NELL-1 can synergistically increase bone formation and regeneration with bone morphogenetic protein 2 (BMP2) and...

journal_title：Journal of molecular histology

authors： Wu J,Wang Q,Han Q,Zhu H,Li M,Fang Y,Wang X

更新日期：2019-06-01 00:00:00

abstract：:Diabetic nephropathy (DN), a serious complication of hyperglycemia, is one of the most common causes of end-stage renal disease (ESRD). Glomerular podocyte injury is a major mechanism that leads to DN. However, the mechanisms underlying podocyte injury are ambiguous. In this study, we sought to investigate the contrib...

journal_title：Journal of molecular histology

authors： Wang X,Liu Q,Kong D,Long Z,Guo Y,Wang S,Liu R,Hai C

更新日期：2020-10-01 00:00:00

abstract：:Vesicular monoamine transporter 2 (VMAT2) is expressed in pancreatic beta cells and has recently been proposed as a target for measurement of beta cell mass in vivo. We questioned, (1) What proportion of beta cells express VMAT2? (2) Is VMAT2 expressed by other pancreatic endocrine or non-endocrine cells? (3) Is the r...

journal_title：Journal of molecular histology

authors： Saisho Y,Harris PE,Butler AE,Galasso R,Gurlo T,Rizza RA,Butler PC

更新日期：2008-10-01 00:00:00

abstract：:Aquaporins (AQPs), the rapid transition pores for water molecules, play an important role in maintenance of intracellular water balance. Studies showed that AQPs were also involved in occurrence, development, invasion and metastasis of tumors. In this study, we aimed to explore the distribution and expression differen...

journal_title：Journal of molecular histology

authors： Ma J,Zhou C,Yang J,Ding X,Zhu Y,Chen X

更新日期：2016-04-01 00:00:00

abstract：:Wnt signaling plays important roles in skeletal development. However, the activation and function of canonical Wnt signaling in joint development remains unclear. We analyzed the lineage identity and developmental changes of the Wnt-responsive cells during synovial joint formation as well as adulthood in the Wnt signa...

journal_title：Journal of molecular histology

authors： Yamagami T,Molotkov A,Zhou CJ

更新日期：2009-08-01 00:00:00

abstract：:Chronic stress is regarded as a significant factor in the etiology of the many diseases. Numerous methods have been developed through which the effect of chronic stress is examined. The aim of this study is to demonstrate the new experimental model for analysis of immuno-suppression induced by chronic restraint stress...

journal_title：Journal of molecular histology

authors： Smieško G,Banović P,Gusman V,Simin V,Cimpean AM,Lalošević D

更新日期：2020-08-01 00:00:00

abstract：:Elevated expression of CXCL9 has been shown to involve in the infiltration of inflammatory cells and liver damage after Hepatitis B virus (HBV) infection. However, whether and by what underlying mechanism does CXCL9 play a role in HBV infection associated hepatocellular carcinoma (HCC) invasion ability remain unclear....

journal_title：Journal of molecular histology

authors： Lan X,Xiao F,Ding Q,Liu J,Liu J,Li J,Zhang J,Tian DA

更新日期：2014-12-01 00:00:00

abstract：:Heparan sulfate proteoglycans (HSPGs) are complex and labile macromolecular moieties on the surfaces of cells that control the activities of a range of extracellular proteins, particularly those driving growth and regeneration. Here, we examine the biosynthesis of heparan sulfate (HS) sugars produced by cultured MC3T3...

journal_title：Journal of molecular histology

authors： Nurcombe V,Goh FJ,Haupt LM,Murali S,Cool SM

更新日期：2007-10-01 00:00:00

abstract：:Alveolar macrophages (AMs) play a vital role in lung immunity. The recent studies demonstrated that potassium channels were associated with macrophage functions, such as activation, migration and cytokines secretion. However, less is known regarding the expression and function of ERG channels in AMs. Our study showed ...

journal_title：Journal of molecular histology

authors： Dong H,Ji Z,Liu M,Wang Y,Bai X,Wang T,Liu Z,Wu Y,Zhang B,Luo Y,Li Z,Dong M

更新日期：2013-02-01 00:00:00

abstract：:Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme that processes blocked 3' ends of DNA breaks. Functional loss of Tdp1 causes spinocerebellar ataxia with axonal neuropathy type 1 (SCAN1). Based on the prominent cytoplasmic expression of Tdp1 in the neurons presumably affected in SCAN1, we hypothesized tha...

journal_title：Journal of molecular histology

authors： Fam HK,Chowdhury MK,Walton C,Choi K,Boerkoel CF,Hendson G

更新日期：2013-08-01 00:00:00

abstract：:Quantitative immunogold procedure was used to study the distribution of molecular components of interendothelial junctions in blood-brain barrier (BBB) microvessels of scrapie infected SJL/J hyperglycemic mice showing obesity and reduced glucose tolerance. Samples of brain (fronto-parietal cerebral cortex and thalamo-...

journal_title：Journal of molecular histology

authors： Vorbrodt AW,Dobrogowska DH,Tarnawski M,Meeker HC,Carp RI

更新日期：2006-01-01 00:00:00

abstract：:In the original publication of the article, two errors were made in describing the equations for Tc. ...

journal_title：Journal of molecular histology

authors： Harris L,Zalucki O,Piper M

更新日期：2018-08-01 00:00:00

abstract：:Spatio-temporal immunolocalizations of cytokeratin 8 (CK8), vimentin, syndecan-1 and Ki-67 were analyzed in ten human incisors and canine tooth germs between the 7th and 20th developmental weeks. CK8 expression was mild to moderate in the epithelial tooth parts, while it shifted from absent or mild in its mesenchymal ...

journal_title：Journal of molecular histology

authors： Kero D,Kalibovic Govorko D,Vukojevic K,Cubela M,Soljic V,Saraga-Babic M

更新日期：2014-12-01 00:00:00

abstract：:Histochemical and morphological research increasingly relies upon quantification of complex biological systems. For such investigations to be meaningful, quantification techniques must meet the seemingly conflicting requirements of being theoretically robust, yet sufficiently practical to facilitate widespread applica...

journal_title：Journal of molecular histology

authors： Hart AM,Terenghi G

更新日期：2004-08-01 00:00:00

abstract：:Zinc is a vital co-factor for insulin metabolism in the pancreatic β-cell, involved in synthesis, maturation, and crystallization. Two families of zinc transporters, namely SLC30A (ZNT) and SLC39A (ZIP) are involved in maintaining cellular zinc homeostasis in mammalian cells. Single nuclear polymorphisms or mutations ...

journal_title：Journal of molecular histology

authors： Cai Y,Kirschke CP,Huang L

更新日期：2018-04-01 00:00:00

abstract：:With the marker of Paneth cells-lysozyme, secretory component (SC) immunoreactivity was demonstrated exclusively in Paneth cells of rat small intestine. The other types of epithelial cells (columnar, goblet, endocrine) were negative. On electron microscopic level, many SC-positive colloidal gold particles were found i...

journal_title：Journal of molecular histology

authors： Tang QJ,Tao KZ,Yun-Liu,Sun XJ,Geng MY,Jiang CL

更新日期：2005-06-01 00:00:00

abstract：:Microscopy is advancing at a rapid pace, enabling high-speed, high-resolution analyses to be conducted in a wide range of cellular contexts. For example, the capacity to quickly capture high-resolution images from multiple optical sections over multiple channels with confocal microscopy has allowed researchers to gain...

journal_title：Journal of molecular histology

authors： Davila RA,Harkins D,Currey L,Fraser J,Bowles J,Piper M

更新日期：2019-12-01 00:00:00

abstract：:MicroRNAs are small noncoding RNAs involved in various biological processes. We characterized the expression of miR-344-3p during mouse embryonic development. At E9.5-E10.5 and E15.5, in situ hybridization detected strong miR-344-3p signal in the central nervous system, including the cerebral cortex, hindbrain, cerebe...

journal_title：Journal of molecular histology

authors： Liu Q,He H,Zeng T,Huang Z,Fan T,Wu Q

更新日期：2014-08-01 00:00:00

abstract：:Tissue microarrays have become an essential tool in translational pathology. They are used to confirm results from other experimental platforms, such as expression microarrays, as well as a primary tool to explore the expression profile of proteins by immunohistochemical analysis. Tissue microarrays are routinely used...

journal_title：Journal of molecular histology

authors： Chung JY,Braunschweig T,Tuttle K,Hewitt SM

更新日期：2007-05-01 00:00:00

abstract：:The neurovascular structures in the cranial dura mater have been studied with various histological techniques in the past years. In order to obtain a proper approach to reveal the detailed structures, different labeling methods for the cranial vessels and nerve fibers were tested in this study. Firstly, the labeling c...

journal_title：Journal of molecular histology

authors： Wang J,Xu D,Cui J,Wang S,She C,Wang H,Wu S,Zhang J,Zhu B,Bai W

更新日期：2020-10-01 00:00:00

abstract：:During their commitment and differentiation toward the osteoblast lineage, mesenchymal stem cells secrete a unique extracellular matrix (ECM) that contains large quantities of glycosaminoglycans (GAGs). Proteoglycans (PGs) are major structural and functional components of the ECM and are composed of a core protein to ...

journal_title：Journal of molecular histology

authors： Grünert M,Dombrowski C,Sadasivam M,Manton K,Cool SM,Nurcombe V

更新日期：2007-10-01 00:00:00

abstract：:During human pregnancy the placenta produces a variety of proteins like steroid hormones and their receptors that are responsible for the establishment and ongoing of the feto-placental unit. Inhibins are dimeric glycoproteins, composed of an alpha-subunit and one of two possible beta-subunits (beta (A) or beta (B)). ...

journal_title：Journal of molecular histology

authors： Mylonas I,Schiessl B,Jeschke U,Vogl J,Makrigiannakis A,Kuhn C,Kunze S,Schulze S,Kainer F,Friese K

更新日期：2006-01-01 00:00:00

abstract：:Recent studies have shown that chronic endothelial dysfunction can impair multiple aspects of renal physiology and, in turn, contribute to renal fibrosis. Sphingosine 1-phosphate (S1P) has been highlighted as an endothelial barrier-stabilizing mediator. The aim of our study was to investigate the effect of FTY720, an ...

journal_title：Journal of molecular histology

authors： Ni H,Chen J,Pan M,Zhang M,Zhang J,Chen P,Liu B

更新日期：2013-12-01 00:00:00

abstract：:The accurately establishment of the eruptive pathway is of vital importance. The mechanisms governing tooth eruption pathway remain little known. This study is to elucidate the roles of Semaphorin 3A (Sema 3A) in mouse tooth eruptive pathway. C57BL/6 mice (11-13 and 15-17 days after birth) were chosen to observe erupt...

journal_title：Journal of molecular histology

authors： Yu X,Zheng F,Du Y,Tang K,Wang W,Zhang S

更新日期：2019-10-01 00:00:00

abstract：:Soluble epoxide hydrolase (sEH) is a bifunctional enzyme with a C-terminal epoxide hydrolase activity and an N-terminal phosphatase activity. Arachidonic acid epoxides, previously suggested to be involved in apoptosis, oncogenesis and cell proliferation, are generated by cytochrome P450 epoxygenases and are good subst...

journal_title：Journal of molecular histology

authors： Enayetallah AE,French RA,Grant DF

更新日期：2006-05-01 00:00:00

abstract：:Neutrotrophins are increasingly appreciated as potential modulators of neuronal function in the adult central nervous system (CNS). To describe the neurotrophin environment within the adult CNS, mRNA and protein expression patterns of neurotrophins-3 and -4 and of brain-derived neurotrophin were investigated in adult ...

journal_title：Journal of molecular histology

authors： Riley CP,Cope TC,Buck CR

更新日期：2004-11-01 00:00:00

abstract：:E3 ubiquitin ligases regulate a variety of biological processes through the ubiquitin-proteasome system, together with ubiquitin activating enzyme E1 and ubiquitin-conjugating enzyme E2. Previous studies have demonstrated that zinc and ring finger 3 (ZNRF3), which belongs to the E3 ubiquitin ligases family is involved...

journal_title：Journal of molecular histology

authors： Zhou Y,Lan J,Wang W,Shi Q,Lan Y,Cheng Z,Guan H

更新日期：2013-10-01 00:00:00