Effect of insulin analogues on 3t3-l1 adipogenesis and lipolysis.

abstract：:Thyroid hormones occasionally appear less effective when administered alone to patients with panhypopituitarism, and manifestations suggestive of hypothyroidism have been reported in patients suffering from untreated Addison's disease. In the latter condition, thyrotropin secretion is increased: this occurs already af...

journal_title：European journal of clinical investigation

authors： De Nayer P,Dozin B,Vandeput Y,Bottazzo FC,Crabbe J

更新日期：1987-04-01 00:00:00

abstract：:Moderate and progressive hypertension was produced experimentally in rats by progressive aortic constriction. The progression of the stenosis was assessed by the differences of pressure across the stenosis. Haemodynamic studies were performed 15, 30 and 60 days after the ligature was placed or after sham operation. Fi...

journal_title：European journal of clinical investigation

authors： Martín-Paredero V,Casado S,López-Novoa JM

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Previous studies revealed that patients with Takotsubo syndrome (TTS) have a higher mortality rate than the general population and a comparable mortality to acute coronary syndrome (ACS). Repolarisation abnormalities, namely T-wave amplitude, may provide incremental prognostic information, in addition to tra...

journal_title：European journal of clinical investigation

authors： Gietzen T,El-Battrawy I,Lang S,Zhou XB,Ansari U,Behnes M,Borggrefe M,Akin I

更新日期：2019-04-01 00:00:00

abstract：:In eleven patients with chronic renal insufficiency treated by intermittent haemodialysis and in ten normal subjects, hepatic and extrahepatic triglyceride lipase activity of post heparin plasma was selectively measured, utilizing the different sensitivity of both enzymes to inhibition by protamine sulphate. In uraemi...

journal_title：European journal of clinical investigation

authors： Bolzano K,Krempler F,Sandhofer F

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:In obese subjects, chronic low-grade inflammation contributes to an increased risk of metabolic abnormalities, which are reversed by weight loss. Sustained weight loss, however, is difficult to achieve and more insight into dietary approaches on anti-inflammatory responses in obese subjects is needed. In thi...

journal_title：European journal of clinical investigation

authors： Jellema A,Plat J,Mensink RP

更新日期：2004-11-01 00:00:00

abstract：:Flow cytometry was used to study phagocytic function and release of reactive oxygen intermediates (ROI) following phagocytosis by granulocytes in 14 patients (six female, eight male) with gram-negative septicaemia prior to, during, and after therapy compared with a group of healthy controls. Phagocytic capacity was as...

journal_title：European journal of clinical investigation

authors： Wenisch C,Parschalk P,Hasenhündl M,Griesmacher A,Graninger W

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:The importance of ascorbate on the production of extracellular matrix proteins (as elastin and collagens) is now well documented, but no studies have been published concerning its effects on fibronectin biosynthesis. Fibronectin is important for cell attachment and for proliferation. MATERIALS AND METHODS:T...

journal_title：European journal of clinical investigation

authors： Péterszegi G,Dagonet FB,Labat-Robert J,Robert L

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Abscess formation is a common bacterial infection and requires an immediate antimicrobial approach for apposite treatment. Delay in patient treatment is usually a common feature, as the bacterial identification of clinical samples is based on the culture, which is a time-consuming exercise. The current study...

journal_title：European journal of clinical investigation

authors： Garg M,Misra MK,Chawla S,Prasad KN,Roy R,Gupta RK

更新日期：2003-06-01 00:00:00

abstract：:Whether leptin levels are related to insulin sensitivity or subject to acute regulation by insulin is not known. In 12 obese [body mass index (BMI) = 34.0 +/- 1.5 kg m-2] and 12 lean (BMI = 22.2 +/- 0.6 kg m-2) non-diabetic subjects, plasma leptin concentrations were measured in the fasting state and during 2 hours of...

journal_title：European journal of clinical investigation

authors： Muscelli E,Camastra S,Masoni A,Baldi S,Sironi AM,Natali A,Ferrannini E

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Cardiovascular patients suffer from reduced blood flow leading to ischaemia and impaired tissue metabolism. Unfortunately, an increasing group of elderly patients cannot be treated with current revascularization methods. Thus, new treatment strategies are urgently needed. Hypoxia-inducible factors (HIFs) upr...

journal_title：European journal of clinical investigation

authors： Niemi H,Honkonen K,Korpisalo P,Huusko J,Kansanen E,Merentie M,Rissanen TT,André H,Pereira T,Poellinger L,Alitalo K,Ylä-Herttuala S

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Although both strength training (ST) and endurance training (ET) seem to be beneficial in type 2 diabetes mellitus (T2D), little is known about post-exercise glucose profiles. The objective of the study was to report changes in blood glucose (BG) values after a 4-month ET and ST programme now that a device f...

journal_title：European journal of clinical investigation

authors： Cauza E,Hanusch-Enserer U,Strasser B,Kostner K,Dunky A,Haber P

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Carotid intima-media thickness and carotid plaque are well-established imaging markers used to capture different stages of the atherosclerotic disease process. We aimed to quantify to which extent carotid intima-media thickness predicts incidence of first-ever carotid plaque. MATERIALS AND METHODS:Two indep...

journal_title：European journal of clinical investigation

authors： Tschiderer L,Klingenschmid G,Seekircher L,Willeit P

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Although several lines of evidence suggest that hypomagnesaemia is a risk factor for developing type 2 diabetes, there are no studies regarding the association between hypomagnesaemia and the risk for developing impaired fasting glucose (IFG) or impaired glucose tolerance (IGT). Our objective was to examine ...

journal_title：European journal of clinical investigation

authors： Guerrero-Romero F,Rascón-Pacheco RA,Rodríguez-Morán M,de la Peña JE,Wacher N

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:  Cirrhotic patients are at considerable risk for bacterial infections, possibly through increased intestinal permeability and bacterial overgrowth. Proton pump inhibitors (PPIs) may increase infection risk. We aimed to explore the potential association between PPI use and bacterial infection risk in cirrhot...

journal_title：European journal of clinical investigation

authors： van Vlerken LG,Huisman EJ,van Hoek B,Renooij W,de Rooij FW,Siersema PD,van Erpecum KJ

更新日期：2012-07-01 00:00:00

abstract：:The collagenolytic activities were assayed in fibroblast cultures established from ten keratoconus and six control corneal explants. The assays included those for both type I and type IV collagenase. The amount of free, directly assayable type I collagenase was highly increased in the media of keratoconus primary cell...

journal_title：European journal of clinical investigation

authors： Ihalainen A,Salo T,Forsius H,Peltonen L

更新日期：1986-02-01 00:00:00

abstract：:The classical view of aldosterone actions via the mineralocorticoid receptor (MR) limited to control of fluid balance and blood pressure homoeostasis has been progressively overcome by clinical and experimental evidence emphasizing the pleiotropic role of MR activation in the pathogenesis of cardiovascular disease. Cl...

journal_title：European journal of clinical investigation

authors： Galuppo P,Bauersachs J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Four peptide hormones of a family of six hormones, i.e. atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-natriuretic peptide (CNP), long acting natriuretic peptide (LANP), vessel dilator and kaliuretic peptide, significantly decrease the number of adenocarcinoma cells in culture. The pres...

journal_title：European journal of clinical investigation

authors： Vesely BA,Song S,Sanchez-Ramos J,Fitz SR,Alli AA,Solivan SM,Gower WR Jr,Vesely DL

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Although the incidence of co-existent pulmonary tuberculosis (PTB) and lung cancer in China is increasing, risk factors related to its development are still poorly understood. We aimed to investigate which clinical factors were associated with the odds of co-existent PTB and lung cancer (PTB-lung cancer) cas...

journal_title：European journal of clinical investigation

authors： Zheng L,Yin J,Wang S,Jiang H,Hu P,Kang Z,Lv P,Li W,Cai C

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Metastatic pheochromocytomas (PCs) and paragangliomas (PGLs) are rare neuroendocrine tumours with a strong genetic background. DESIGN:We searched the PubMed database through February 2015 to identify studies characterizing metastatic PCs/PGLs as well as currently established and evolving therapies. RESULTS...

journal_title：European journal of clinical investigation

authors： Angelousi A,Kassi E,Zografos G,Kaltsas G

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Irisin, a novel myokine, has been shown to increase following vigorous exercise, with studies suggesting that it mediates some of the beneficial effects of exercise. Irisin might play a role in 'browning' of white adipocytes, thus increasing energy expenditure. The role of irisin in exercise and energy expen...

journal_title：European journal of clinical investigation

authors： Al-Daghri NM,Alokail MS,Rahman S,Amer OE,Al-Attas OS,Alfawaz H,Tripathi G,Sabico S,Chrousos GP,McTernan PG,Piya MK

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Clusterin (Apolipoprotein J), a plasma protein with cytoprotective and complement-inhibiting activities, localizes in the infarcted heart during myocardial infarction (MI). Recently, we have shown a protective effect of exogenous clusterin in vitro on ischaemically challenged cardiomyocytes independent of co...

journal_title：European journal of clinical investigation

authors： Van Dijk A,Vermond RA,Krijnen PA,Juffermans LJ,Hahn NE,Makker SP,Aarden LA,Hack E,Spreeuwenberg M,van Rossum BC,Meischl C,Paulus WJ,Van Milligen FJ,Niessen HW

更新日期：2010-10-01 00:00:00

abstract：:Critical illness is an aetiologically and clinically heterogeneous syndrome that is characterised by organ failure and immune dysfunction. Mortality in critically ill patients is driven by inflammation-associated organ damage and a profound vulnerability to nosocomial infection. Both factors are influenced by the acti...

journal_title：European journal of clinical investigation

authors： Wood AJT,Vassallo A,Summers C,Chilvers ER,Conway-Morris A

更新日期：2018-12-01 00:00:00

abstract：:The developmental aspects of characteristic intestinal lipoprotein synthesis, chlomicrons (CM), very low density lipoproteins (VLDL) and high density lipoproteins (HDL), are unknown. Our objective was to determine the ontogeny of intestinal lipid and lipoprotein synthesis in both the jejunum and the ileum. Explants of...

journal_title：European journal of clinical investigation

authors： Mehran M,Thibault L,Russo P,Garofalo C,Levy E

更新日期：1992-02-01 00:00:00

abstract：:Adequate pregnancy care of women with systemic lupus erythematosus (SLE) rests on three pillars: a coordinated medical-obstetrical care, an agreed and well-defined management protocol and a good neonatal unit. Pregnancy should be planned following a preconceptional visit for counselling. Women with severe active disea...

journal_title：European journal of clinical investigation

authors： Ruiz-Irastorza G,Khamashta MA

更新日期：2011-06-01 00:00:00

abstract：:The release of PGI2-like activity into the circulation in response to cholinergic agonists and modification of this response by beta-adrenergic antagonists was investigated in anaesthetized cats and healthy humans. Antiaggregatory activity in the arterial blood was continuously assayed by measuring platelet aggregatio...

journal_title：European journal of clinical investigation

authors： Swies J,Radomski M,Dembińska-Kieć A,Korbut R,Gryglewski RJ,Brandt R,Nowak J

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Minimal lipoprotein(a) [Lp(a)] target values are advocated for high-risk cardiovascular patients. We investigated the prognostic value of Lp(a) in the acute setting of patients with acute coronary syndromes (ACS). MATERIALS AND METHODS:Plasma levels of Lp(a) were collected at time of angiography from 1711 p...

journal_title：European journal of clinical investigation

authors： Gencer B,Rigamonti F,Nanchen D,Vuilleumier N,Kern I,Aghlmandi S,Klingenberg R,Räber L,Auer R,Carballo D,Carballo S,Heg D,Windecker S,Lüscher TF,Matter CM,Rodondi N,Mach F

更新日期：2019-07-01 00:00:00

abstract：:Deoxyribonucleic acid synthesis requires adequate cellular concentrations of the four deoxyribonucleoside triphosphates. Using a sensitive enzymic assay, we have measured the concentrations (pools) of these compounds in human bone marrow cells and in lymphocytes. The mean concentrations (pmol/10(6) cells) in normal hu...

journal_title：European journal of clinical investigation

authors： Tattersall MH,Lavoie A,Ganeshaguru K,Tripp E,Hoffbrand AV

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:Preliminary data suggest that serum uric acid (SUA) could be involved in the prognosis of chronic heart failure (HF). The aim of our study was to test the relationship between SUA and left ventricular ejection fraction (EF%) in a cohort of elderly hypertensive outpatients with chronic HF. DESIGN:We consecut...

journal_title：European journal of clinical investigation

authors： Borghi C,Cosentino ER,Rinaldi ER,Cicero AF

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Buerger's disease (BD) is a segmental occlusive vascular disease. The aim of this study was to detect functional changes in brachial artery and asymptomatic morphological changes in extra-cranial carotid arteries not affected by the disease process and to assess markers of inflammation and endothelial damage...

journal_title：European journal of clinical investigation

authors： Joras M,Poredos P,Fras Z

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The use of Procion orange dye (POD) is one of the most widely accepted techniques to assess sarcolemmal damage. This phenomenon has been related to functional adaptation in skeletal muscles. The POD method includes intravenous injection of this colorant in vivo, enabling its identification inside those fibre...

journal_title：European journal of clinical investigation

authors： Palacio J,Gāldiz JB,Alvarez FJ,Orozco-Levi M,Lloreta J,Gea J

更新日期：2002-06-01 00:00:00