Hepatic and extrahepatic triglyceride lipase activity in uraemic patients on chronic haemodialysis.

abstract：:The influence of insulin on lipolysis and glucose metabolism in abdominal adipose tissue was studied in situ with the microdialysis technique during a euglycaemic insulin clamp (1 mU kg-1 min-1) in nine cirrhotic patients and 10 controls. The cirrhotic patients displayed a 50% decrease in glucose utilization rate duri...

journal_title：European journal of clinical investigation

authors： Johansson U,Arner P,Bolinder J,Hagström-Toft E,Ungerstedt U,Eriksson LS

更新日期：1993-12-01 00:00:00

abstract：:The serum concentrations of collagen type IV,7S, collagen type IV,nc1, and aminoterminal type III procollagen peptide immunoreactive components were measured by means of specific radioimmunoassays during development of granulation tissue in rats. The results were compared with tissue deposition of basement membranes a...

journal_title：European journal of clinical investigation

authors： Hørslev-Petersen K,Pedersen LR,Bentsen KD,Brocks D,Garbarsch C,Kim KY,Hahn EG,Schuppan D,Lorenzen I

更新日期：1988-08-01 00:00:00

abstract：:The effect of indomethacin (75 mg/day for 3 days) on the response to i.v. angiotensin II was investigated in eight healthy, sodium-repleted, male subjects. Indomethacin reduced the release of aldosterone during the i.v. administration of angiotensin II (5, 10 and 20 ng kg-1 min-1), whereas the pressor response to angi...

journal_title：European journal of clinical investigation

authors： Vierhapper H,Waldhäusl W,Nowotny P

更新日期：1981-04-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia is a common feature of the nephrotic syndrome (NS). From retrospective studies, it has been suggested that aggressive lipid-lowering with low-density lipoprotein apheresis (LDL-A) may not only improve dyslipidemia but also decrease urinary albumin excretion and increase serum levels of albumin...

journal_title：European journal of clinical investigation

authors： Stenvinkel P,Alvestrand A,Angelin B,Eriksson M

更新日期：2000-10-01 00:00:00

abstract：:We investigated the influence of sodium fluoride on polymorphonuclear leukocyte (PMN) adhesiveness in a healthy subject with low serum levels of fluoride. The PMN were separated from venous blood, and the percentages of adhered and unadhered cells were determined in vitro in plastic culture plates. The cells were cult...

journal_title：European journal of clinical investigation

authors： Gómez-Ubric JL,Liébana J,Gutiérrez J,Castillo A

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:A hyaluronan-loading test has been developed for assessment of hyaluronan kinetics and applied in patients with liver and joint diseases. This test describes the metabolic process of hyaluronan but cannot define the specific contribution of different organs. A method for labelling of hyaluronan with the shor...

journal_title：European journal of clinical investigation

authors： Lindqvist U,Westerberg G,Bergström M,Torsteindottir I,Gustafson S,Sundin A,Lööf L,Långström B

更新日期：2000-07-01 00:00:00

abstract：:The pathogenesis of alcoholic fatty liver is unknown, but several causes have been proposed based on biochemical findings. These include the metabolism of alcohol leading to a shift in the cytosolic [NAD+]/ [NADH] ratio to reduction, which in turn causes a direct inhibition of beta-oxidation and enhanced triacylglycer...

journal_title：European journal of clinical investigation

authors： Eaton S,Record CO,Bartlett K

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Glomerulonephritis clusters in families. However, infections are common inducers of glomerulonephritis and may also cluster in families. Studies of adoptees and their biological and adoptive parents may disentangle genetic from environmental causes of familial clustering. This is the first adoption study aim...

journal_title：European journal of clinical investigation

authors： Akrawi DS,Zöller B,Fjellstedt E,Sundquist J,Sundquist K,PirouziFard M

更新日期：2019-08-01 00:00:00

abstract：:Alpha-naphthyl-isothiocyanate (ANIT)-induced intrahepatic cholangitis was associated with significant polyuria in rats. The urine output in the experimental rats was about two and a half to four fold higher than that in the controls. The polyuria was accompanied by polydypsia and disappeared when water intake was limi...

journal_title：European journal of clinical investigation

authors： Tur-Kaspa R,Adler R,Popovtzer MM,Eliakim M

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Although several lines of evidence suggest that hypomagnesaemia is a risk factor for developing type 2 diabetes, there are no studies regarding the association between hypomagnesaemia and the risk for developing impaired fasting glucose (IFG) or impaired glucose tolerance (IGT). Our objective was to examine ...

journal_title：European journal of clinical investigation

authors： Guerrero-Romero F,Rascón-Pacheco RA,Rodríguez-Morán M,de la Peña JE,Wacher N

更新日期：2008-06-01 00:00:00

abstract：:Insulin resistance has been reported in normal ageing but discrepancies between such studies may be related to compounding factors such as body composition and exercise patterns. We employed a two-step hyperinsulinaemic euglycaemic clamp to assess peripheral and hepatic tissue insulin sensitivity and glucose recycling...

journal_title：European journal of clinical investigation

authors： Broughton DL,James OW,Alberti KG,Taylor R

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:In obese subjects, chronic low-grade inflammation contributes to an increased risk of metabolic abnormalities, which are reversed by weight loss. Sustained weight loss, however, is difficult to achieve and more insight into dietary approaches on anti-inflammatory responses in obese subjects is needed. In thi...

journal_title：European journal of clinical investigation

authors： Jellema A,Plat J,Mensink RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Diabetes dramatically increases the risk of cardiovascular complications and mortality. Hydrogen sulphide plays an important role in reducing oxidative stress. Several studies demonstrated that hydrogen sulphide protects islet beta cells from oxidant stress damage and decreases apoptosis. The aim of...

journal_title：European journal of clinical investigation

authors： Dorofeyeva N,Drachuk K,Rajkumar R,Sabnis O,Sagach V

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The use of Procion orange dye (POD) is one of the most widely accepted techniques to assess sarcolemmal damage. This phenomenon has been related to functional adaptation in skeletal muscles. The POD method includes intravenous injection of this colorant in vivo, enabling its identification inside those fibre...

journal_title：European journal of clinical investigation

authors： Palacio J,Gāldiz JB,Alvarez FJ,Orozco-Levi M,Lloreta J,Gea J

更新日期：2002-06-01 00:00:00

abstract：:We have examined the impact of race and positive family history of type 2 diabetes on glucose/insulin dynamics and the two components of glucose disposal in healthy, first-degree relatives of black and white American patients with type 2 diabetes mellitus who are at a greater risk from the disease and their healthy co...

journal_title：European journal of clinical investigation

authors： Osei K,Cottrell DA

更新日期：1994-12-01 00:00:00

abstract：:Although in therapeutic use for more than a century, the mode of cellular action of organic nitrates remains incompletely understood. Despite ample experimental evidence from animal studies to show that nitrates are metabolized to NO in the vascular smooth muscle, direct demonstration of such an activity in human vasc...

journal_title：European journal of clinical investigation

authors： Feelisch M,Brands F,Kelm M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Gastrointestinal symptoms are common on acute exposure to high-altitude (HA). Underlying mechanisms are not understood, but vascular shunting away from the gut could be responsible. Therefore, blood flow in the superior mesenteric artery (SMA) and hepatic portal vein (HPV) was examined at sea level (SL) and ...

journal_title：European journal of clinical investigation

authors： Kalson NS,Hext F,Davies AJ,Chan CW,Wright AD,Imray CH,Birmingham Medical Research Expeditionary Society.

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Burnout represents a syndrome that is related to demanding job characteristics combined with the absence of resources or motivational job characteristics. The aim of this position study was to present strategies that individuals use to minimize burnout and its unfavourable effects. MATERIALS AND METHODS:The...

journal_title：European journal of clinical investigation

authors： Demerouti E

更新日期：2015-10-01 00:00:00

abstract：:The contribution of the kinetics of exogeneous and endogenous lipoproteins in determining the level of triglyceride in fasting plasma was assessed in a group of 19 normolipidaemic and hypertriglyceridaemic subjects. From data derived during a 9-h infusion of [15N]-glycine, we have assessed very low density lipoprotein...

journal_title：European journal of clinical investigation

authors： Cortner JA,Le NA,Coates PM,Bennett MJ,Cryer DR

更新日期：1992-03-01 00:00:00

abstract：INTRODUCTION:Smoking is associated with dyslipidaemia, particularly raised plasma triglycerides and reduced high-density lipoprotein (HDL)-cholesterol and a delayed clearance of triglyceride in fat tolerance tests. The aim of this study was to investigate whether these phenomena could be explained by a reduced lipoprot...

journal_title：European journal of clinical investigation

authors： Freeman DJ,Caslake MJ,Griffin BA,Hinnie J,Tan CE,Watson TD,Packard CJ,Shepherd J

更新日期：1998-07-01 00:00:00

abstract：:During chronic high-altitude (HA) exposure, basal and exercise-induced noradrenaline (NA) increases do not parallel blood pressure (BP) changes observed; unlike beta-adrenergic receptors, to our knowledge no data are available on alpha-receptors. We studied platelet alpha 2- and leucocyte beta-receptors and basal cate...

journal_title：European journal of clinical investigation

authors： Zaccaria M,Borea PA,Opocher G,Ponchia A,Varani K,Fraccarollo D,Scandellari C

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Chronic lung diseases contribute significantly to the morbidity and mortality of the population. There are few effective treatments for many chronic lung diseases, and even fewer therapies that can arrest or reverse the progress of the disease. DESIGN:In this review, we present the current state of regenera...

journal_title：European journal of clinical investigation

authors： Anversa P,Perrella MA,Kourembanas S,Choi AM,Loscalzo J

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The detection of important immunocompetence-like features on endocrine steroid cells raises questions about direct intercellular communication between the adrenal and immune systems. This article summarizes our recent work and new data on immune-adrenal interactions. MATERIALS AND METHODS:RT-PCR and immunoh...

journal_title：European journal of clinical investigation

authors： Marx C,Bornstein SR,Wolkersdörfer GW

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia is a relatively uncommon but severe side-effect of heparin therapy. Heparin-induced IgG antibody has been elucidated to be the main isotype and the most pathogenic antibody in the pathophysiology. As affected patients are at high risk of developing thrombotic events, confirma...

journal_title：European journal of clinical investigation

authors： Wang LC,Huhle G,Malsch R,Hoffmann V,Song XL,Harenberg J

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Studies evaluating the relationship between soluble transferrin receptor (sTfR), a biomarker inversely related to body iron stores, and risk of type 2 diabetes mellitus (T2DM) are scarce and inconclusive. Furthermore, sTfR concentrations have been observed to be significantly higher in obese than in nonobese...

journal_title：European journal of clinical investigation

authors： Fernández-Cao JC,Arija V,Aranda N,Basora J,Diez-Espino J,Estruch R,Fitó M,Corella D,Salas-Salvadó J

更新日期：2017-03-01 00:00:00

abstract：:To examine the possible effects of hyperoxalaemia on anaerobic metabolism and erythrocyte pyruvate kinase activity, we induced a rise in plasma oxalate in 11 dialysis patients by the oral administration of ascorbic acid, 500 mg day-1 for 3 weeks. Blood samples were taken from the same antecubital vein before and after...

journal_title：European journal of clinical investigation

authors： Tomson CR,Channon SM,Ward MK,Laker MF

更新日期：1990-08-01 00:00:00

abstract：:Plasma glucose concentration is the best predictor for the development of non-insulin-dependent diabetes mellitus (NIDDM). However, obesity is also a recognized risk factor for development of the disease, and is easier to track over time. Thus obesity could be of considerable clinical importance as a predictor of diab...

journal_title：European journal of clinical investigation

authors： Ferrannini E,Camastra S

更新日期：1998-09-01 00:00:00

abstract：:Total serum haemolytic complement activity, plasma fibrinogen, erythrocyte sedimentation rate and other biological values in forty-three patients with Hodgkin's disease were correlated with results of staging. A highly significant increase (P=10(-5)) of the mean total serum haemolytic complement activity was found in ...

journal_title：European journal of clinical investigation

authors： Wagener DJ,Haanen C

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Immunosuppression associated with surgery may predispose to increased tumour growth or recurrence. Lymphocytes are central components of the immune network, signalling specific and non-specific responses in tumour immunosurveillance. This study was therefore designed to compare the effects of minimally invas...

journal_title：European journal of clinical investigation

authors： Leaver HA,Craig SR,Yap PL,Walker WS

更新日期：2000-03-01 00:00:00

abstract：:Lipid and carbohydrate metabolism variables were studied in twenty-eight patients with chronic renal failure (mean GFR 7.7 +/- 2.5 ml/min) and uraemic symptoms. 71% of the patients had hypertriglyceridaemia (greater than or equal to 2.2 mmol/l). Total serum cholesterol was normal while VLDL cholesterol was high and al...

journal_title：European journal of clinical investigation

authors： Attman PO,Gustafson A

更新日期：1979-08-01 00:00:00