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Sonography-guided percutaneous microwave ablation of intrahepatic primary cholangiocarcinoma.

Abstract：

OBJECTIVE:To evaluate the efficacy and safety of sonography-guided percutaneous microwave ablation of intrahepatic primary cholangiocarcinoma. MATERIALS AND METHODS:From May 2006 to March 2010, 15 patients (11 men, 4 women; mean age, 57.4 years) with 24 histologically proven intrahepatic primary cholangiocarcinoma lesions (mean tumor size, 3.2±1.9 cm; range, 1.3-9.9 cm) were treated with microwave ablation. RESULTS:Thirty-eight sessions were performed for 24 nodules in 15 patients. The follow-up period was 4-31 months (mean, 12.8±8.0 months). The ablation success rate, the technique effectiveness rate, and the local tumor progression rate were 91.7% (22/24), 87.5% (21/24), and 25% (6/24) respectively according to the results of follow-up. The cumulative overall 6, 12, 24 month survival rates were 78.8%, 60.0%, and 60.0%, respectively. Major complication occurred including liver abscess in two patients (13.3%) and needle seeding in one patient (6.7%). Both complications were cured satisfied with antibiotic treatment combined to catheter drainage for abscess and resection for needle seeding. The minor complications and side effects were experienced by most patients which subsided with supportive treatment. CONCLUSION:Microwave ablation can be used as a safe and effective technique to treat intrahepatic primary cholangiocarcinoma.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Yu MA,Liang P,Yu XL,Cheng ZG,Han ZY,Liu FY,Yu J

doi

10.1016/j.ejrad.2011.01.014

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

548-52

issue

2

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(11)00043-X

journal_volume

80

pub_type

杂志文章

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