Abstract:
OBJECTIVES:We investigated the role of novel intra-abdominal parameters measured by computed tomography (CT) in the prediction of clinical outcomes in acute pancreatitis (AP). METHODS:Patients with AP underwent an abdominal CT scan on admission to define different intra-abdominal parameters (abdominal circumference, peritoneal cavity circumference, intraabdominal visceral fat area, and subcutaneous fat area) at the L2-L3 level using the open-source image analysis software Osirix Lite v.11.0.4 to predict clinical outcomes. RESULTS:Eighty patients with AP were analyzed. Peritoneal cavity circumference (PCC) was the only variable independently associated with outcomes. PCC showed an area under ROC for prediction of severity in AP of 0.830. A PCC ≥ 85 cm increased the risk of severity of AP (RR 15.7), persistent systemic inflammatory response syndrome (RR 9.3), acute peripancreatic fluid collection (RR 6.4), necrotizing pancreatitis (RR 21.50), and mortality (RR 2.4). We found a 4.7-fold increase in the risk of developing severe AP for each 10 cm increase in PCC. CONCLUSIONS:PCC measurement at the L2-L3 level using a non-enhanced abdominal CT scan on admission in patients with AP is useful in the early prediction of severity, persistent systemic inflammatory response syndrome, local complications, and mortality.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Monreal-Robles R,Kohn-Gutiérrez AE,Sordia-Ramírez J,Zúñiga-Segura JA,Palafox-Salinas JA,de la Rosa-Pacheco S,Elizondo-Riojas G,González-González JAdoi
10.1016/j.ejrad.2020.109327subject
Has Abstractpub_date
2020-11-01 00:00:00pages
109327eissn
0720-048Xissn
1872-7727pii
S0720-048X(20)30516-7journal_volume
132pub_type
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