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Imaging after vascular gene therapy.

Abstract：

:Targets for cardiovascular gene therapy currently include limiting restenosis after balloon angioplasty and stent placement, inhibiting vein bypass graft intimal hyperplasia/stenosis, therapeutic angiogenesis for cardiac and lower-limb ischemia, and prevention of thrombus formation. While catheter angiography is still standard method to follow-up vascular gene transfer, other modern imaging techniques, especially intravascular ultrasound (IVUS), magnetic resonance (MR), and positron emission tomography (PET) imaging provide complementary information about the therapeutic effect of vascular gene transfer in humans. Although molecular imaging of therapeutic gene expression in the vasculatures is still in its technical development phase, it has already offered basic medical science an extremely useful in vivo evaluation tool for non- or minimally invasive imaging of vascular gene therapy.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Manninen HI,Yang X

doi

10.1016/j.ejrad.2005.03.019

keywords:

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

165-70

issue

2

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(05)00126-9

journal_volume

56

pub_type

杂志文章,评审

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