Abstract:
BACKGROUND:Coronary atherosclerosis has traditionally been proposed to be associated with several cardiovascular risk factors and anthropometric measures. However, clinical data regarding the independent value of visceral adipose tissue in addition to such traditional predictors remains obscure. MATERIALS AND METHODS:We subsequently studied 719 subjects (age: 48.1±8.3 years, 25% females) who underwent multidetector computed tomography (MDCT) for coronary calcium score (CCS) quantification. Baseline demographic data and anthropometric measures were taken with simultaneous body fat composition estimated. Visceral adipose tissue of pericardial and thoracic peri-aortic fat was quantified by MDCT using TeraRecon Aquarius workstation (San Mateo, CA). Traditional cardiovascular risk stratification was calculated by metabolic (NCEP ATP III) and Framingham (FRS) scores and high-sensitivity CRP (Hs-CRP) was taken to represent systemic inflammation. The independent value of visceral adipose tissue to systemic inflammation and CCS was assessed by utilizing multivariable regression analysis. RESULTS:Of all subjects enrolled in this study, the mean values for pericardial and peri-aortic adipose tissue were 74.23±27.51 and 7.23±3.69ml, respectively. Higher visceral fat quartile groups were associated with graded increase of risks for cardiovascular diseases. Both adipose burdens strongly correlated with anthropometric measures including waist circumference, body weight and body mass index (all p<0.001). In addition, both visceral amount correlates well with ATP and FRS scores, all lipid profiles and systemic inflammation marker in terms of Hs-CRP (all p<0.001). After adjustment for baseline variables, both visceral fat were independently related to Hs-CRP levels (all p<0.05), but only pericardial fat exerted independent role in coronary calcium deposit. CONCLUSION:Both visceral adipose tissues strongly correlated with systemic inflammation beyond traditional cardiovascular risks and anthropometric measures, though only pericardial fat exerted independent role in coronary calcium deposit. Our data suggested that visceral adipose tissue may thus contribute to systemic inflammation and play an independent role in the pathogenesis of atherosclerosis.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Yun CH,Lin TY,Wu YJ,Liu CC,Kuo JY,Yeh HI,Yang FS,Chen SC,Hou CJ,Bezerra HG,Hung CL,Cury RCdoi
10.1016/j.ejrad.2011.01.035subject
Has Abstractpub_date
2012-04-01 00:00:00pages
749-56issue
4eissn
0720-048Xissn
1872-7727pii
S0720-048X(11)00064-7journal_volume
81pub_type
杂志文章abstract:OBJECTIVE:To determine whether CT features can predict the pathological tumor grades of pancreatic neuroendocrine tumors (PanNETs) according to the recent WHO classification. MATERIALS AND METHODS:In all, 28 patients with histologically confirmed PanNETs underwent preoperative contrast CT examinations. Thirteen tumors...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.05.005
更新日期:2015-08-01 00:00:00
abstract::The authors report a case of thrombosis of the distal end of an enlarged right posterior epidural vein. The patient had a markedly narrow lumbar canal due to 1.5 spondylolisthesis. The dilated vein and the thrombosis were displayed by computed tomography but remained unrecognized until surgery. Pathogenesis of this co...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
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abstract::The recent advent of multislice-scanning is the first real quantum leap in computed tomography since the introduction of spiral CT in the early 90s. We discuss basic theoretical considerations important for the design of multislice scanners. Then, specific issues, like the design of the detector and spiral interpolati...
journal_title:European journal of radiology
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更新日期:1999-08-01 00:00:00
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journal_title:European journal of radiology
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abstract::The purpose of this study was to evaluate by CT the usefulness of the non-distension of the stomach in determining invasion of the gastric cancer into perigastric space and adjacent organs. Forty-eight patients with pathologically proved gastric cancer were studied by conventional CT. Patients were examined using two ...
journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:1998-11-01 00:00:00
abstract:INTRODUCTION:Transplant renal artery (RA) stenosis (TRAS) is the most frequent posttransplantation vascular complication. Contrast enhanced magnetic resonance (CeMRA) angiography has been established as the preferred imaging technique for the evaluation of TRAS because it does not require the use of iodinated contrast ...
journal_title:European journal of radiology
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2013-10-01 00:00:00
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journal_title:European journal of radiology
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更新日期:2001-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.04.009
更新日期:2010-07-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.12.019
更新日期:2015-04-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.11.035
更新日期:2013-12-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章,评审
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更新日期:2015-11-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2012-07-01 00:00:00
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更新日期:2006-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.09.030
更新日期:2010-01-01 00:00:00
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journal_title:European journal of radiology
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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更新日期:2011-02-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章,评审
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更新日期:2010-03-01 00:00:00
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journal_title:European journal of radiology
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更新日期:2011-03-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.05.040
更新日期:2014-09-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/0720-048x(90)90057-i
更新日期:1990-11-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:To examine the efficacy of qualitative shear wave elastography (SWE) in the classification and evaluation of solid breast masses, and to compare this method with conventional ultrasonograghy (US), quantitative SWE parameters and qualitative SWE classification proposed before. METHODS:From April 2015 to Marc...
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更新日期:2017-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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更新日期:2017-01-01 00:00:00