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Radiation dose of CT coronary angiography in clinical practice: objective evaluation of strategies for dose optimization.

Abstract：

BACKGROUND:CT coronary angiography (CTCA) is an evolving modality for the diagnosis of coronary artery disease. Radiation burden associated with CTCA has been a major concern in the wider application of this technique. It is important to reduce the radiation dose without compromising the image quality. OBJECTIVES:To estimate the radiation dose of CTCA in clinical practice and evaluate the effect of dose-saving algorithms on radiation dose and image quality. METHODS:Effective radiation dose was measured from the dose-length product in 616 consecutive patients (mean age 58 ± 12 years; 70% males) who underwent clinically indicated CTCA at our institution over 1 year. Image quality was assessed subjectively using a 4-point scale and objectively by measuring the signal- and contrast-to-noise ratios in the coronary arteries. Multivariate linear regression analysis was used to identify factors independently associated with radiation dose. RESULTS:Mean effective radiation dose of CTCA was 6.6 ± 3.3 mSv. Radiation dose was significantly reduced by dose saving algorithms such as 100 kV imaging (-47%; 95% CI, -44% to -50%), prospective gating (-35%; 95% CI, -29% to -40%) and ECG controlled tube current modulation (-23%; 95% CI, -9% to -34%). None of the dose saving algorithms were associated with a significant reduction in mean image quality or the frequency of diagnostic scans (P = non-significant for all comparisons). CONCLUSION:Careful application of radiation-dose saving algorithms in appropriately selected patients can reduce the radiation burden of CTCA significantly, without compromising the image quality.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Yerramasu A,Venuraju S,Atwal S,Goodman D,Lipkin D,Lahiri A

doi

10.1016/j.ejrad.2011.02.040

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

1555-61

issue

7

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(11)00225-7

journal_volume

81

pub_type

杂志文章

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