Thrombocytopenic thrombotic purpura: severe clinic with no CT, minor MRI, but a SPECT correlate.

Abstract:

:A 28-year-old woman with primarily therapy refractory TTP was followed neuroradiologically over 6 months. Despite pronounced neurological and neuropsychiatric symptoms including hemiparesis and aphasia she had unremarkable CT scans on two occasions. Three MRI exams showed no correlate for her neurological symptoms except a small petechial cortical hemorrhage in the right parietooccipital gyrus which may account for her TTP-related anxiety disorder. A cerebral HMPAO-SPECT showed long-standing right-sided hypoperfusion compatible with residual vasculature changes. The possible causes for the clinico-neuroradiological discrepancies are discussed in view of the literature.

journal_name

Eur J Radiol

authors

Baron Y,Bargemann T,Harten P,Gutschmidt HJ

doi

10.1016/s0720-048x(98)00088-6

keywords:

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

56-62

issue

1

eissn

0720-048X

issn

1872-7727

pii

S0720048X98000886

journal_volume

31

pub_type

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