Abstract:
OBJECTIVES:We aimed to study the ability of contrast enhanced MRI at 1.5 T and 11C-acetate PET/CT, both individually and using fused data, to detect localized prostate cancer. METHODS:Thirty-six men with untreated prostate cancer and negative for metastatic disease on pelvic CT and bone scan were prospectively enrolled. A pelvic 11C-acetate PET/CT scan was performed in all patients, and a contrast enhanced MRI scan in 33 patients (6 examinations using both endorectal coil and surface coils, and 27 examinations using surface coils only). After the imaging studies 10 patients underwent prostatectomy and 26 were treated by image guided external beam radiation treatment. Image fusion of co-registered PET and MRI data was performed based on anatomical landmarks visible on CT and MRI using an advanced in-house developed software package. PET/CT, MRI and fused PET/MRI data were evaluated visually and compared with biopsy findings on a lobar level, while a sextant approach was used for patients undergoing prostatectomy. RESULTS:When using biopsy samples as method of reference, the sensitivity, specificity and accuracy for visual detection of prostate cancer on a lobar level by contrast enhanced MRI was 85%, 37%, 73% and that of 11C-acetate PET/CT 88%, 41%, 74%, respectively. Fusion of PET with MRI data increased sensitivity, specificity and accuracy to 90%, 72% and 85%, respectively. CONCLUSIONS:Fusion of sequentially obtained PET/CT and MRI data for the localization of prostate cancer is feasible and superior to the performance of each individual modality alone.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Jambor I,Borra R,Kemppainen J,Lepomäki V,Parkkola R,Dean K,Alanen K,Arponen E,Nurmi M,Aronen HJ,Minn Hdoi
10.1016/j.ejrad.2011.12.043subject
Has Abstractpub_date
2012-11-01 00:00:00pages
2966-72issue
11eissn
0720-048Xissn
1872-7727pii
S0720-048X(12)00024-1journal_volume
81pub_type
杂志文章abstract:PURPOSE:To evaluate the radiologic and clinicopathologic factors in radiologic-pathologic discordance (false-negative results) in breast cancer patients who demonstrate radiologic complete response (rCR) in MR imaging after neoadjuvant chemotherapy (NAC). METHOD:Our institutional review board approved this retrospecti...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.06.017
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:We investigated whether the prerequisite of the maximum slope and deconvolution methods are satisfied in pancreatic perfusion CT and whether the measured parameters between these algorithms are correlated. METHODS:We examined nine beagles injected with iohexol (200 mgI kg(-1)) at 5.0 ml s(-1). The abdominal ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.06.016
更新日期:2011-01-01 00:00:00
abstract::Pelvic fractures are common in polytrauma and continue to pose a difficult management dilemma for even the most experienced clinicians. Due to the high energy mechanisms involved, there are often multiple other injuries and many specialists may be involved. Deriving an effective management strategy relies on early dia...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2010.01.025
更新日期:2010-04-01 00:00:00
abstract::Real-time elastography (RTE) performed during endoscopic ultrasound (EUS) is a relatively new technique which allows the evaluation of tissue stiffness, with the intent of better characterising lesions during EUS examinations. The aim of this comprehensive review was to describe the technique of RTE-EUS, as well as th...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2013.03.023
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:To evaluate the value of a vessel removal algorithm in segmentation of subsolid nodules by comparing the software solid component measurement on CT, before and after vessel removal, with the measurement of the invasive component on pathology in lung adenocarcinomas manifesting as subsolid nodules. MATERIALS AN...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.01.016
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:Image-guided percutaneous biopsy is the recommended initial diagnostic procedure for suspicious mammographic lesions. This study was conducted to determine the accuracy of the Intact(®) breast lesion excision system (BLES) and to identify predictive factors for complete excision and underestimation. MATERIAL...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.01.049
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:Acute appendicitis is known for one of the most common cause of acute abdomen. However, it is still challenging to clearly distinguish complicated from uncomplicated appendicitis preoperatively. We investigated the association between right hydronephrosis and complicated appendicitis compared with other compu...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109241
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:To study MRI findings of abdominal wall edema (AWE) in acute pancreatitis as well as correlations between AWE and the severity of acute pancreatitis according to the MR severity index (MRSI) and the Acute Physiology And Chronic Healthy Evaluation III (APACHE III) scoring system. MATERIALS AND METHODS:A total...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.04.005
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:To elucidate the utility of PROPELLER for motion artefact reduction on shoulder MRI and to examine the influence of streak artefacts on diagnosis of clinical images. METHODS:15 healthy volunteers and 48 patients underwent shoulder MRI with/without PROPELLER (coronal oblique proton density-fast spin echo [PD...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2016.07.008
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:To develop and evaluate the performance of a fully-automated convolutional neural network (CNN)-based algorithm to evaluate hepatobiliary phase (HBP) adequacy of gadoxetate disodium (EOB)-enhanced MRI. Secondarily, we explored the potential of the proposed CNN algorithm to reduce examination length by applying ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.108837
更新日期:2020-03-01 00:00:00
abstract::Teleradiology is probably the most successful eHealth service available today. Its business model is based on the remote transmission of radiological images (e.g. X-ray and CT-images) over electronic networks, and on the interpretation of the transmitted images for diagnostic purpose. Two basic service models are comm...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.10.018
更新日期:2010-01-01 00:00:00
abstract::A total of 7 healthy volunteers and 31 patients have been examined clinically, by MRI, TRS, and biopsy. In those patients with established carcinoma, a CT examination was also performed. For the MRI study, a superconducting MR 2000 imager (Picker International) operated at 0.15 T was used with multiplanar SE and IR se...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract::The new American Thoracic Society/European Respiratory Society (ATS/ERS) update to the multidisciplinary classification of idiopathic interstitial pneumonias (IIPs) defines both rare IIPs and rare histologic patterns of IIPs. Although these diseases are rare, each has some distinguishing imaging and pathologic charact...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.11.032
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The management of community-acquired pneumonia (CAP) depends, in part, on the identification of the causative agents. The objective of this study was to determine the potential of thin-section computed tomography (CT) in differentiating bacterial and non-bacterial pneumonia. PATIENTS AND METHO...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.08.004
更新日期:2009-12-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the computed tomography (CT) features of 2-5 cm gastric gastrointestinal stromal tumors (GISTs), schwannomas and leimyomas which have close relationship with malignancy evaluation and differential diagnosis. METHOD:Seventy-six patients with pathologically confirmed ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.108783
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To ascertain the role of respiratory-gated PET/CT with (18)F-fluorodeoxyglucose ((18)F-FDG) for accurate diagnosis of liver metastasis. MATERIALS AND METHODS:Forty patients with suspected liver metastasis underwent conventional whole-body PET/CT scan initially, followed by respiratory-gated PET/CT scan coverin...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.05.019
更新日期:2013-10-01 00:00:00
abstract:AIM:Positron emission tomography (PET) using F18-flurodeoxy-glucose (FDG) has been widely used for reflecting cellular metabolism. However, the feasibility of FDG PET in the diagnosis of hepatocellular carcinoma (HCC) is limited. The aim of the study was to assess the ability of FDG PET (PET/CT) in the detection of ext...
journal_title:European journal of radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ejrad.2011.08.004
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:The aim of this systematic review was to compare the diagnostic accuracy, subjective image quality and clinical consequences of 3D-fluoroscopy with standard imaging modalities (2D-fluoroscopy, X-ray or CT) during reduction and fixation of intra-articular upper and lower extremity fractures. METHODS:A system...
journal_title:European journal of radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ejrad.2012.06.021
更新日期:2012-12-01 00:00:00
abstract::In the present study ultrasonography observed the tail of the pancreas more frequently through the spleen than by any other approach. If the splenic approach fails, examination through the fluid-filled stomach may be tried. ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract:OBJECTIVES:To investigate whether a dose reduction of Gadobutrol for renal magnetic resonance angiography (MRA) at 7 Tesla (T) is feasible while preserving diagnostic image quality. METHODS:Ten healthy volunteers were enrolled for a renal MRA on a 7T scanner. Fast low angle shot (FLASH) MRA data sets were obtained uti...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2016.11.007
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To analyze the impact of tube potential and iodine concentration on the visibility of calcified plaques in coronary computed tomography angiography (cCTA). METHODS & MATERIALS:164 consecutive patients (65.9 % men and a mean age of 57.1 ± 11.3 years) with suspected coronary artery disease underwent calcium scor...
journal_title:European journal of radiology
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doi:10.1016/j.ejrad.2020.109276
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:To prospectively evaluate the clinical value of real-time ultrasonography (US)-computed tomography (CT)/magnetic resonance imaging (MRI) fusion imaging for percutaneous needle biopsy of focal liver lesions (FLLs), and to compare its biopsy success rate with that of conventional US-guided biopsy in a propensi...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.04.002
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:The purpose of this retrospective study was to determine what gives rise to the periportal free air, and ligamentum teres and falciform ligament signs on CT in patients with gastrointestinal (GI) tract perforation, and whether these specific air distributions can play a clinically meaningful role in the diagnos...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.07.033
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To examine factors associated with one step surgery in case of non-palpable breast cancer. MATERIALS AND METHODS:Clinical data of 152 consecutively diagnosed patients with breast cancer were analyzed retrospectively. Preoperative diagnostic findings were divided in subgroups: mammographically visible mass/micr...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.02.033
更新日期:2007-12-01 00:00:00
abstract::Although magnetic resonance imaging has become the dominant modality for cross-sectional musculo-skeletal imaging, the widespread availability, speed, and versatility of computed tomography (CT) continue to make it a mainstay of emergency room (ER) diagnostic imaging. Pelvic ring and acetabular fractures occur as the ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2003.11.019
更新日期:2004-04-01 00:00:00
abstract:PURPOSE:To assess the utility of a 2D dynamic HASTE sequence in assessment of cervical spine flexion-extension, specifically (1) comparing dynamic spondylolisthesis to radiographs and (2) assessing dynamic contact upon or deformity of the cord. METHODS:Patients with a dynamic flexion-extension sagittal 2D HASTE sequen...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.109447
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Standard stroke CT protocols start with non-enhanced CT followed by perfusion-CT (PCT) and end with CTA. We aimed to evaluate the influence of the sequence of PCT and CTA on quantitative perfusion parameters, venous contrast enhancement and examination time to save critical time in the therapeutic window in s...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.01.011
更新日期:2013-06-01 00:00:00
abstract::MR imaging directly shows integrity of spinal cord, and provides sensitive assessments of structurally important soft tissue investments of the vertebral column. High-resolution images should be acquired in at least two planes, with T1 and fluid sensitive sequences. In the acute and subacute settings, MR may be used t...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/s0720-048x(03)00201-8
更新日期:2003-10-01 00:00:00
abstract::NMR examinations were performed on a total of 109 patients using a resistive magnet. In 67 patients various organs and tissues of the face and neck the trunk and the limbs were evaluated in axial, sagittal and coronal planes. The use of more than one sequence time is essential for adequate representation of the anatom...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:
更新日期:1983-02-01 00:00:00
abstract:OBJECTIVES:To investigate the time-course of late gadolinium enhancement of infarcted myocardium using gadobenate dimeglumine at different dosages and administration regimens. MATERIALS AND METHODS:After institutional review board approval and informed consent, we studied 13 patients (aged 63±11 years) with chronic my...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.06.040
更新日期:2011-10-01 00:00:00