Abstract:
OBJECTIVE:To prospectively evaluate the diagnostic efficacy of conventional ultrasound (US), contrast-enhanced US (CEUS), the combined use of two modalities, and magnetic resonance imaging (MRI) in the differentiation of focal solid breast lesions. MATERIALS AND METHODS:61 patients with BI-RADS category 3-5 breast lesions detected at conventional US underwent CEUS and MRI. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic performance of conventional US, CEUS, combination of two modalities and MRI for discrimination between benign and malignant breast lesions. RESULTS:Tissue specimens of 61 breast lesions were obtained either from surgical resection (n=46) or from needle biopsy (n=15). Histopathologic diagnosis revealed 28 benign and 33 malignant lesions. The diagnostic performance of conventional US and CEUS in differentiating benign from malignant breast lesions showed no significant difference (P=0.741). The combination of two modalities significantly improved the diagnostic accuracy compared with either conventional US or CEUS alone (P=0.031 and P=0.012, respectively). The area under the ROC curve (A(z)) value for the combined use of two modalities for discrimination between benign and malignant breast lesions was 0.94, and that for MRI was 0.91, whereas no statistical difference was found between them (P=0.296). CONCLUSION:The combined use of conventional US and CEUS has a better diagnostic performance than either method alone and displays good agreement with MRI in the differentiation capability for benign and malignant breast lesions.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Du J,Wang L,Wan CF,Hua J,Fang H,Chen J,Li FHdoi
10.1016/j.ejrad.2012.09.004subject
Has Abstractpub_date
2012-12-01 00:00:00pages
3890-9issue
12eissn
0720-048Xissn
1872-7727pii
S0720-048X(12)00418-4journal_volume
81pub_type
杂志文章abstract::Ultrasonography (US) is a readily available non-invasive tool useful for the detection of musculoskeletal and soft tissue masses. Although X-Ray is often the first imaging study for evaluating both bone and soft tissue lesions, and magnetic resonance imaging and computed tomography are mandatory in lesions staging, US...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
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更新日期:2017-05-01 00:00:00
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
pub_type: 杂志文章
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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journal_title:European journal of radiology
pub_type: 杂志文章,随机对照试验
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更新日期:2011-12-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章,meta分析,评审
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journal_title:European journal of radiology
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journal_title:European journal of radiology
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更新日期:2011-09-01 00:00:00
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journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2012.10.029
更新日期:2013-03-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:1995-07-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2002-06-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.10.013
更新日期:2013-03-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00
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journal_title:European journal of radiology
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journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2006.08.027
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Biopsy of the musculoskeletal system is useful in the management of bone lesions particularly in oncology but they are often challenging procedures with a significant risk of complications. Computed tomography (CT)-guided needle biopsies may decrease these risks but doubts still exist about their diagnosti...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.06.055
更新日期:2011-01-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章,多中心研究
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更新日期:2020-05-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.11.008
更新日期:2011-12-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2009.02.011
更新日期:2009-06-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.12.048
更新日期:2012-02-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.02.040
更新日期:2012-07-01 00:00:00