Abstract:
OBJECTIVE:To assess computed tomography (CT) evaluation of mediastinal nodes in non-small cell lung cancer to predict metastatic involvement by measurement of their axis and surface area in the coronal plane, as compared to standard short-axis measures in the axial plane. METHODS:Evaluation of mediastinal nodes was retrospectively performed on CT scans of 100 patients before thoracotomy. In all patients, mediastinal dissection was performed in the appropriate stations (n=264) according to the side (59 right, 41 left) of the tumor. Measurements of short axis and surface area of the largest node in each dissected station were performed on axial and coronal planes. RESULTS:By using the standard threshold of axial short axis ≥10 mm, sensitivity and specificity were 25% and 98%, respectively. Areas under receiver operating characteristic curves were 0.828 and 0.821 for axial short axis and axial surface area data. For comparison, areas under receiver operating characteristic curves were 0.843 and 0.845 for coronal short axis and coronal surface area data, respectively. So, for a specificity of 98%, sensitivity was 29% for coronal short axis ≥11 mm and 33% for coronal surface area ≥123 mm(2). When using axial short axis ≥10 mm or coronal surface area ≥120 mm(2), sensitivity was 45%, whereas specificity remained at 96%. CONCLUSION:Coronal measurements of mediastinal nodes give a slightly albeit non-significant improvement of diagnostic accuracy over axial ones. If both axial short axis and coronal surface area are taken into account, accuracy is improved.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Guinet C,Rousset P,Bobbio A,Alifano M,Damotte D,Régnard JF,Buy JNdoi
10.1016/j.ejrad.2011.06.015subject
Has Abstractpub_date
2012-09-01 00:00:00pages
2440-3issue
9eissn
0720-048Xissn
1872-7727pii
S0720-048X(11)00554-7journal_volume
81pub_type
临床试验,杂志文章abstract::In order to adequately visualize the ossicles and other fine structures in the middle ear, sophisticated radiological methods are essential. The temporal bone has been studied with hypocycloidal tomography using conventional films and xerotomography in 60 patients with cholesteatoma. In 53 of the patients xerotomograp...
journal_title:European journal of radiology
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pub_type: 临床试验,杂志文章
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