Dual energy computed tomography analysis in cancer patients: What factors affect iodine concentration in contrast enhanced studies?

Abstract:

PURPOSE:The aim of the study is to explore the patient's and scan's parameters that affect the iodine concentration in the abdomen using dual energy computed tomography (DECT) in an oncologic population. METHOD:This is a retrospective study with consecutive patients with different cancers who underwent a single-source DECT (ssDECT) examinations at our institution between years 2015 and 2017. On axial IODINE images, the radiologist manually drew a circular ROI along the inner contour of the aorta. Mean iodine concentration and ROI areas were recorded. Body mass index for every patient was recorded. Descriptive statistics were summarized for iodine concentration and patient/scan characteristics. Linear regression was used to examine associations between iodine concentration in aorta and studied characteristics. Statistical significance was set at a p value < 0.05. RESULTS:The univariate analysis, showed a statistically significant association between iodine concentration within the aorta and the area of ROI (Estimated Coefficient β: -0.013), the rate of injection (Estimated Coefficient β: 2.09), the acquisition time (Estimated Coefficient β: -0.195). In multivariable analysis iodine concentration in the aorta increased with higher rate of injection (4 ml/sec), smaller ROI area and lower BMI. CONCLUSION:Our results showed how iodine concentration is highly dependent on some intrinsic and extrinsic parameters of the examination. These parameters should be taken into account since lower concentration of iodine decrease contrast-to-noise ratio, and in longitudinal follow up studies, they would affect iodine quantitive assessments in cancer patients with frequent chemotherapy-induced variations in BMI and cardiac function.

journal_name

Eur J Radiol

authors

Corrias G,Sawan P,Mahmood U,Zheng J,Capanu M,Salvatore M,Spinato G,Saba L,Mannelli L

doi

10.1016/j.ejrad.2019.108698

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

108698

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(19)30348-1

journal_volume

120

pub_type

杂志文章
  • Screening US and CT for blunt abdominal trauma: a retrospective study.

    abstract:OBJECTIVE:To assess the accuracy of screening US and CT in patients with blunt abdominal trauma admitted to the trauma centre of our General Hospital. MATERIALS AND METHOD:The abdominal US reports of 864 primary trauma patients (139 with major and 725 with minor injuries) and 162 CT reports of a subgroup of the same s...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2005.02.001

    authors: Marco GG,Diego S,Giulio A,Luca S

    更新日期:2005-10-01 00:00:00

  • Depiction of normal gastrointestinal anatomy with MDCT: comparison of low- and high-attenuation oral contrast media.

    abstract:PURPOSE:To compare low- and high-attenuation oral contrast media for depiction of normal gastrointestinal anatomy with multidetector-row computed tomography (MDCT). MATERIALS AND METHODS:A prospective, randomized study of 90 consecutive patients without known or suspected gastrointestinal disease was conducted after t...

    journal_title:European journal of radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ejrad.2007.05.015

    authors: Erturk SM,Mortelé KJ,Oliva MR,Ichikawa T,Silverman SG,Cantisani V,Pagliara E,Ros PR

    更新日期:2008-04-01 00:00:00

  • Synthesized image processing in clinical neurosurgery.

    abstract::In an effort to achieve efficient image management in clinical neurosurgery utilizing a local image filing system (EFPACS, Fuji Electric Co., Ltd), adequate image-processing and display techniques were developed. One is a method whereby the anatomical location of the thalamic and basal ganglion lesions is determined b...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/0720-048x(90)90092-p

    authors: Kikuchi K,Kowada M,Ogayama H,Sasanuma J,Watanabe K

    更新日期:1990-01-01 00:00:00

  • Percutaneous sclerotherapy of a giant benign renal cyst with alcohol.

    abstract::We report a case of giant, benign renal cyst that was treated with percutaneous aspiration and sclerotherapy using 95% alcohol. A seven French catheter was inserted into the cyst under ultrasonographic and fluoroscopic guidance, and was then left in place to drain the cyst contents. Approximately 4 l of fluid was drai...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/s0720-048x(01)00280-7

    authors: Bozkurt FB,Boyvat F,Tekin I,Aytekin C,Coskun M,Ozkardes H

    更新日期:2001-10-01 00:00:00

  • Digital chest radiography--comparing two types of CRT monitors in a ROC experiment with a chest phantom.

    abstract::Two principally different 1000-line CRT (cathode ray tube) monitors connected to a digital image intensifier system for chest radiography were compared in terms of image quality and viewing comfort. Image quality was assessed by means of ROC analysis. Five observers tried to find simulated pathology positioned over th...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/0720-048x(96)00750-4

    authors: Kheddache S,Angelhed JE,Månsson LG,Denbratt L,Gottfridsson B,Olmarker A

    更新日期:1996-06-01 00:00:00

  • Combined pre-treatment MRI and 18F-FDG PET/CT parameters as prognostic biomarkers in patients with cervical cancer.

    abstract:OBJECTIVE:To determine the associations of quantitative parameters derived from multiphase contrast-enhanced magnetic resonance imaging (CE-MRI), diffusion-weighted (DW) MRI and 18F-fluorodeoxyglucose (18F-FDG) positron-emission tomography/computed tomography (PET/CT) with clinico-histopathological prognostic factors, ...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2014.03.024

    authors: Miccò M,Vargas HA,Burger IA,Kollmeier MA,Goldman DA,Park KJ,Abu-Rustum NR,Hricak H,Sala E

    更新日期:2014-07-01 00:00:00

  • Spiral CT: thoracic applications.

    abstract::Volumetric CT data acquisition has had a major impact on the practice of computed tomography. This article reviews the current state of knowledge of the applications of this technique to the chest disease summarising its clinical impact on the assessment of lung and airways diseases, mediastinal abnormalities (excludi...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0720-048x(98)00007-2

    authors: Padhani AR

    更新日期:1998-08-01 00:00:00

  • Differentiation of primary central nervous system lymphoma from high-grade glioma and brain metastasis using arterial spin labeling and dynamic contrast-enhanced magnetic resonance imaging.

    abstract:BACKGROUND AND PURPOSE:Conventional magnetic resonance imaging (MRI) is sometimes difficult to distinguish primary central nervous system lymphoma (PCNSL) from other malignant brain tumors effectively. The study aimed to evaluate the diagnostic performance of arterial spin labeling (ASL) and dynamic contrast-enhanced (...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2019.01.008

    authors: Xi YB,Kang XW,Wang N,Liu TT,Zhu YQ,Cheng G,Wang K,Li C,Guo F,Yin H

    更新日期:2019-03-01 00:00:00

  • Mammography with and without radiolucent positioning sheets: Comparison of projected breast area, pain experience, radiation dose and technical image quality.

    abstract:PURPOSE:To compare projected breast area, image quality, pain experience and radiation dose between mammography performed with and without radiolucent positioning sheets. METHODS:184 women screened in the Dutch breast screening programme (May-June 2012) provided written informed consent to have one additional image ta...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2015.07.005

    authors: Timmers J,Voorde MT,Engen RE,Landsveld-Verhoeven Cv,Pijnappel R,Greve KD,Heeten GJ,Broeders MJ

    更新日期:2015-10-01 00:00:00

  • A correlative study of aortic valve rotation angle and thoracic aortic sizes using ECG gated CT angiography.

    abstract:OBJECTIVE:Various degrees of aortic valve rotation may be seen in individuals with no history of congenital cardiovascular malformations, but its association with aortic sizes has not been studied. METHODS:Gated computed tomographic (CT angiograms in 217 patients were studied (66.7±15; 22-97 years old)). Aortic diamet...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2017.01.009

    authors: Saremi F,Cen S,Tayari N,Alizadeh H,Emami A,Lin L,Fleischman F

    更新日期:2017-04-01 00:00:00

  • Awareness of radiation protection and dose levels of imaging procedures among medical students, radiography students, and radiology residents at an academic hospital: Results of a comprehensive survey.

    abstract:PURPOSE:To evaluate the awareness of radiation protection issues and the knowledge of dose levels of imaging procedures among medical students, radiology residents, and radiography students at an academic hospital. MATERIAL AND METHODS:A total of 159 young doctors and students (including 60 radiology residents, 56 med...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2016.10.033

    authors: Faggioni L,Paolicchi F,Bastiani L,Guido D,Caramella D

    更新日期:2017-01-01 00:00:00

  • Intravoxel incoherent motion diffusion-weighted MRI in patients with breast cancer: Correlation with tumor stroma characteristics.

    abstract:PURPOSE:To determine whether imaging parameters derived from intravoxel incoherent motion (IVIM) diffusion weighted imaging (DWI) vary according to tumor-stroma ratio(TSR) or dominant stroma type of breast cancer. METHODS:We prospectively enrolled 77 patients with breast cancer who underwent IVIM DWI on a 3.0 T MR sca...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2019.108686

    authors: Li Y,Wang Z,Chen F,Qin X,Li C,Zhao Y,Yan C,Wu Y,Hao P,Xu Y

    更新日期:2019-11-01 00:00:00

  • Upper tract urothelial cancer.

    abstract::While urothelial carcinoma is a very common tumor, involvement of the upper tract is relatively uncommon. Consequently, there are no consensus imaging recommendations for upper tract disease. CT urography is the dominant imaging modality for the upper tract, but despite its excellent performance characteristics and be...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejrad.2017.10.021

    authors: Froemming A,Potretzke T,Takahashi N,Kim B

    更新日期:2018-01-01 00:00:00

  • Computed tomography fluoroscopy-guided cutting needle biopsy of pulmonary nodules ≤8 mm: A retrospective study including 117 nodules.

    abstract:PURPOSE:To evaluate the diagnostic yield and safety of computed tomography (CT) fluoroscopy-guided cutting needle biopsy (CNB) for pulmonary nodules ≤ 8 mm. METHOD:Data of CT fluoroscopy-guided CNB for pulmonary nodules ≤ 8 mm performed in a single institution were retrospectively analyzed. One hundred and seventeen b...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2020.108903

    authors: Zhao Y,Matsui Y,Hiraki T,Iguchi T,Tomita K,Uka M,Gobara H,Toyooka S,Kanazawa S

    更新日期:2020-04-01 00:00:00

  • Juxta-adrenal schwannoma: dynamic multi-slice CT and MRI findings.

    abstract:BACKGROUND:We retrospectively analyzed the MSCT and MRI findings of three cases of juxta-adrenal schwannoma and reviewed literature. METHODS AND RESULTS:Three patients were male, and showed no signs for endocrine activity. The three cases of juxta-adrenal schwannoma were all well-circumscribed, oval masses with cystic...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2011.01.082

    authors: Liu QY,Gao M,Li HG,Lin XF,Huang SQ,Liang BL

    更新日期:2012-04-01 00:00:00

  • The prognostic value of multidetector CT features in predicting overall survival outcomes in patients with pancreatic neuroendocrine tumors.

    abstract:PURPOSE:To assess the prognostic value of multidetector CT in predicting overall survival outcomes in patients with pancreatic neuroendocrine tumors (PNETs). METHOD:Seventy-one patients pathologically diagnosed with PNETs were retrospectively included. The clinical and imaging information was evaluated by two radiolog...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2020.108847

    authors: Yang B,Chen HY,Zhang XY,Pan Y,Lu YF,Yu RS

    更新日期:2020-03-01 00:00:00

  • Assessment of ameloblastomas using MRI and dynamic contrast-enhanced MRI.

    abstract::We retrospectively evaluated magnetic resonance images (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) of ameloblastomas. MRI and DCE-MRI were performed for 10 ameloblastomas. We obtained the following results from the MRI and DCE-MRI. (a) Ameloblastomas can be divided into solid and cystic portions on the basis of ...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2005.01.006

    authors: Asaumi J,Hisatomi M,Yanagi Y,Matsuzaki H,Choi YS,Kawai N,Konouchi H,Kishi K

    更新日期:2005-10-01 00:00:00

  • Measurement of single kidney contrast media clearance by multiphasic spiral computed tomography: preliminary results.

    abstract:OBJECTIVE:We present preliminary results of a new method (hereinafter called 'CT-clearance') to measure single kidney contrast media clearance by performing multiphasic helical CT of the kidneys. CT-clearance was calculated according to an extension of the Patlak-Plot. In contrast to prior investigators, who repeatedly...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/s0720-048x(01)00323-0

    authors: Hackstein N,Puille MF,Bak BH,Scharwat O,Rau WS

    更新日期:2001-09-01 00:00:00

  • Post-mortem virtual estimation of free abdominal blood volume.

    abstract:PURPOSE:The purpose of this retrospective study was to examine the reliability of virtually estimated abdominal blood volume using segmentation from postmortem computed tomography (PMCT) data. MATERIALS AND METHODS:Twenty-one cases with free abdominal blood were investigated by PMCT and autopsy. The volume of the bloo...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2011.09.014

    authors: Ampanozi G,Hatch GM,Ruder TD,Flach PM,Germerott T,Thali MJ,Ebert LC

    更新日期:2012-09-01 00:00:00

  • Lymphatic interventions for isolated, iatrogenic chylous ascites: A multi-institution experience.

    abstract:OBJECTIVES:Lymphangiography and thoracic duct embolization are established treatments for post-surgical chylothorax. There is only limited experience in their application to treat post-surgical chylous ascites. A multi-center analysis of the technical and clinical success of lymphangiography and lymphatic interventions...

    journal_title:European journal of radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ejrad.2018.10.019

    authors: Majdalany BS,Khayat M,Downing T,Killoran TP,El-Haddad G,Khaja MS,Saad WA

    更新日期:2018-12-01 00:00:00

  • Diagnostic value of MRI in comparison to scintigraphy, PET, MS-CT and PET/CT for the detection of metastases of bone.

    abstract::The initial localization of metastases in the bone in patients with solid tumors has a relatively good prognosis in comparison with visceral metastasization. The early detection of bone marrow metastases allows for a rapid initiation of therapy and a subsequent reduction in the morbidity rate. Modern MRI is superior t...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejrad.2005.01.016

    authors: Ghanem N,Uhl M,Brink I,Schäfer O,Kelly T,Moser E,Langer M

    更新日期:2005-07-01 00:00:00

  • Evaluation of fatty pancreas by proton density fat fraction using 3-T magnetic resonance imaging and its association with pancreatic cancer.

    abstract:PURPOSE:To evaluate whether pancreatic magnetic resonance imaging-proton density fat fraction (MRI-PDFF) correlates with histological pancreatic fat fraction and its possible usefulness as a biomarker of pancreatic cancer compared with pancreatic index (PI) using computed tomography (CT number of the pancreas divided b...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2019.06.024

    authors: Fukui H,Hori M,Fukuda Y,Onishi H,Nakamoto A,Ota T,Ogawa K,Ninomiya K,Tatsumi M,Osuga K,Yamada D,Eguchi H,Miyoshi E,Tomiyama N

    更新日期:2019-09-01 00:00:00

  • Magnetic resonance imaging of intracranial atherosclerosis: Comparison of ex vivo 3T MRI and histologic findings.

    abstract:PURPOSE:Imaging the lipid-rich necrotic core (LRNC) is very important when evaluating the response of lipid-lowering therapy. The purpose of this study was to assess ex vivo LRNC of intracranial atherosclerosis using 3T MRI. MATERIALS AND METHODS:Thirty-one atherosclerotic lesions from 17 specimens were analyzed (basi...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2017.10.013

    authors: Chung GH,Kwak HS,Hwang SB,Noh SJ

    更新日期:2017-12-01 00:00:00

  • The Chiari III malformation: an unusual and asymptomatic variant in an 11-year old child.

    abstract::Chiari III malformation is an extremely rare condition, and is characterized by the hindbrain herniation into a low occipital or high cervical encephalocele together with the pathologic and imaging features of the Chiari II malformation. In this report, an unusual variant of the Chiari III malformation was diagnosed i...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/s0720-048x(01)00334-5

    authors: Sirikci A,Bayazit YA,Bayram M

    更新日期:2001-09-01 00:00:00

  • Magnetic resonance imaging in the evaluation of the gastric emptying and antral motion: feasibility and reproducibility of a fast not invasive technique.

    abstract:PURPOSE:The aim of this study was to evaluate reproducibility of a fast MRI protocol to measure gastric emptying and motility of the gastric antrum. METHODS AND MATERIALS:Gastric emptying and antral speed were measured in 12 type 1 diabetic patients (mean age 43 years) and 9 healthy volunteers (mean age 31 years). Sub...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2009.04.071

    authors: Carbone SF,Tanganelli I,Capodivento S,Ricci V,Volterrani L

    更新日期:2010-08-01 00:00:00

  • Prediction of muscle invasion of bladder cancer: A comparison between DKI and conventional DWI.

    abstract:OBJECTIVES:To prospectively compare the diagnostic efficacy of conventional diffusion-weighted imaging (DWI) and diffusion kurtosis imaging (DKI) in differentiating between muscle-invasive bladder cancer (MIBC) and non-muscle-invasive bladder cancer (NMIBC). METHODS:Multiple b value DWIs were performed using a 3-T mag...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2021.109522

    authors: Li Q,Cao B,Tan Q,Liu K,Jiang S,Zhou J

    更新日期:2021-01-06 00:00:00

  • Renal MDCT.

    abstract::Multidetector CT has expanded the utility of CT by improving longitudinal resolution and acquisition speed. Applications include diagnosis of renal vascular and parenchymal injuries, renal tumor diagnosis and staging, the emerging field of CT urography and CT angiography. This summary review illustrates MDCT approache...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0720-048x(03)00003-2

    authors: Foley WD

    更新日期:2003-03-01 00:00:00

  • Influence of fluid-attenuated inversion-recovery on stroke apparent diffusion coefficient measurements and its clinical application.

    abstract:BACKGROUND AND PURPOSE:The application of a fluid-attenuated inversion-recovery pulse with a conventional diffusion-weighted MRI sequence (FLAIR DWI) decreases the partial volume effects from cerebrospinal fluid on apparent diffusion coefficient (ADC) measurements. For this reason, FLAIR DWI may be more useful in the e...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2009.11.029

    authors: Ni JM,Mogensen MA,Chen ZA,Shuang C,Shen TZ,Huang G

    更新日期:2010-08-01 00:00:00

  • Permeability to macromolecular contrast media quantified by dynamic MRI correlates with tumor tissue assays of vascular endothelial growth factor (VEGF).

    abstract:PURPOSE:To correlate dynamic MRI assays of macromolecular endothelial permeability with microscopic area-density measurements of vascular endothelial growth factor (VEGF) in tumors. METHODS AND MATERIAL:This study compared tumor xenografts from two different human cancer cell lines, MDA-MB-231 tumors (n=5), and MDA-MB...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2011.07.016

    authors: Cyran CC,Sennino B,Fu Y,Rogut V,Shames DM,Chaopathomkul B,Wendland MF,McDonald DM,Brasch RC,Raatschen HJ

    更新日期:2012-05-01 00:00:00

  • Clinical utility of real-time ultrasound-multimodality fusion guidance for percutaneous biopsy of focal liver lesions.

    abstract:OBJECTIVES:To prospectively evaluate the clinical value of real-time ultrasonography (US)-computed tomography (CT)/magnetic resonance imaging (MRI) fusion imaging for percutaneous needle biopsy of focal liver lesions (FLLs), and to compare its biopsy success rate with that of conventional US-guided biopsy in a propensi...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2018.04.002

    authors: Ahn SJ,Lee JM,Chang W,Lee SM,Kang HJ,Yang HK,Han JK

    更新日期:2018-06-01 00:00:00