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Local thermal ablation of renal cell carcinoma.

Abstract：

PURPOSE:With evolving local thermal ablation technology, the clinical application of thermal ablation has been actively investigated in the treatment for renal cell carcinoma. We review the evolution and current status of radiofrequency ablation and microwave ablation for renal cell carcinoma. MATERIALS AND METHODS:All articles published in English on radiofrequency ablation or microwave ablation as a treatment for renal cell carcinoma were identified with a MEDLINE® and PubMed® search from 1990 to 2010. RESULTS:Local thermal ablation has several advantages, including keeping more normal renal units, relatively simple operation, easy tolerance, fewer complications, a shorter hospitalization and convalescence period. Long-term data has determined radiofrequency ablation is responsible for poor surgical candidates with renal cell carcinoma, however, tumor size, location and shape might affect the efficacy of radiofrequency ablation. Microwave ablation can induce large ablation volumes and yield good local tumor control. Associated complications appear to be low. CONCLUSIONS:Local ablative approaches seem to represent an attractive alternative to extirpative surgery for the treatment of small renal neoplasms in select patients. Potential developments include concepts to improve the accuracy and effectiveness of thermal ablation by improving the guiding, monitoring capabilities and detection capacity of multi-center lesions to provide at least equivalent cancer control to conventional surgery.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Feng B,Liang P

doi

10.1016/j.ejrad.2010.12.056

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

437-40

issue

3

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(10)00681-9

journal_volume

81

pub_type

杂志文章,评审

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