Abstract:
OBJECTIVE:To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). METHODS:Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software. RESULTS:Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p<0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5-59.9], 20.3 [16.2-25.9] and 14.0 [11.2-17.7], respectively, all p<0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3-168.4], 138.7 [90.6-191.7], 147.0 [100.7-183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1-144.6], 110.2 [63.8-166.6], 115.9 [81.7-164.2], respectively, p<0.05 all). High-attenuation non-calcified volumes (90-129 HU) yielded similar values with FBP and HIR (p=0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30-89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p=0.22 and p=0.67, respectively). CONCLUSIONS:IMR improves image quality of coronary CTA and decreases calcified plaque volumes.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Károlyi M,Szilveszter B,Kolossváry M,Takx RA,Celeng C,Bartykowszki A,Jermendy ÁL,Panajotu A,Karády J,Raaijmakers R,Giepmans W,Merkely B,Maurovich-Horvat Pdoi
10.1016/j.ejrad.2016.12.012subject
Has Abstractpub_date
2017-02-01 00:00:00pages
83-89eissn
0720-048Xissn
1872-7727pii
S0720-048X(16)30402-8journal_volume
87pub_type
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