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Iron conservation by reduction of metalloenzyme inventories in the marine diazotroph Crocosphaera watsonii.

Abstract：

:The marine nitrogen fixing microorganisms (diazotrophs) are a major source of nitrogen to open ocean ecosystems and are predicted to be limited by iron in most marine environments. Here we use global and targeted proteomic analyses on a key unicellular marine diazotroph Crocosphaera watsonii to reveal large scale diel changes in its proteome, including substantial variations in concentrations of iron metalloproteins involved in nitrogen fixation and photosynthesis, as well as nocturnal flavodoxin production. The daily synthesis and degradation of enzymes in coordination with their utilization results in a lowered cellular metalloenzyme inventory that requires ∼40% less iron than if these enzymes were maintained throughout the diel cycle. This strategy is energetically expensive, but appears to serve as an important adaptation for confronting the iron scarcity of the open oceans. A global numerical model of ocean circulation, biogeochemistry and ecosystems suggests that Crocosphaera's ability to reduce its iron-metalloenzyme inventory provides two advantages: It allows Crocosphaera to inhabit regions lower in iron and allows the same iron supply to support higher Crocosphaera biomass and nitrogen fixation than if they did not have this reduced iron requirement.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Saito MA,Bertrand EM,Dutkiewicz S,Bulygin VV,Moran DM,Monteiro FM,Follows MJ,Valois FW,Waterbury JB

doi

10.1073/pnas.1006943108

subject

Has Abstract

pub_date

2011-02-08 00:00:00

pages

2184-9

issue

6

eissn

0027-8424

issn

1091-6490

pii

1006943108

journal_volume

108

pub_type

杂志文章

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