Action of 6-(p-hydroxyphenylazo)-uracil on bacteriophage IG 1.

Abstract:

:IG 1, a temperate phage of Bacillus subtilis, is strongly induced from its lysogens by 6-(p-hydroxyphenylazo)-uracil, an azopyrimidine known as selectively inhibiting the B. subtilis DNA polymerase III. IG 1 phages originated either by induction or infection multiply, abundantly, in the presence of that azopyrimidine, in spite of the drastic decline of cell viability. Chloramphenicol completely suppresses the induction effect and also blocks the formation of spontaneously induced phage particles.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Fernandes RM,de Lencastre H,Archer LJ

doi

10.1007/BF01316671

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

177-81

issue

3-4

eissn

0304-8608

issn

1432-8798

journal_volume

113

pub_type

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